Astaxanthin inhibits H2O2-mediated apoptotic cell death in mouse neural progenitor cells via modulation of p38 and MEK signaling pathways

Journal of Microbiology and Biotechnology

Volumn 19, Issue 11, 2009, Pages 1355-1363

  Kim, Jeong Hwan ^a   Choi, Woobong ^a   Lee, Jong Hwan ^a   Jeon, Sung Jong ^a   Choi, Yung Hyun ^a   Kim, Byung Woo ^a   Chang, Hyo Ihl ^b   Nam, Soo Wan ^a  

^a Dong Eui University   (South Korea)

^b Korea University   (South Korea)

Author keywords

Antioxidant; Apoptotic cell death; Astaxanthin; H2O2; Mouse neural progenitor cells

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENOSINE TRIPHOSPHATE; ASTAXANTHIN; CASPASE; CYTOCHROME C; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; CASPASE 3; CASPASE 9; ENZYME INHIBITOR; FLAVONOID; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; OXIDIZING AGENT; PYRIDINE DERIVATIVE; XANTHOPHYLL;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MODULATION; MOUSE; NERVE CELL CULTURE; NERVE CELL GROWTH; NERVE CELL NECROSIS; NEURAL STEM CELL; NEUROPROTECTION; NONHUMAN; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CULTURE TECHNIQUE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHYSIOLOGY; SPINAL CORD; STEM CELL;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 9; CELL CULTURE TECHNIQUES; ENZYME INHIBITORS; FLAVONOIDS; HYDROGEN PEROXIDE; IMIDAZOLES; MAP KINASE KINASE KINASES; MICE; OXIDANTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; SIGNAL TRANSDUCTION; SPINAL CORD; STEM CELLS; XANTHOPHYLLS;

EID: 71549114866     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.0906.06003     Document Type: Article

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