Mice lacking mPGES-1 are resistant to lithium-induced polyuria

American Journal of Physiology - Renal Physiology

Volumn 297, Issue 6, 2009, Pages

  Jia, Zhanjun ^a   Wang, Haiping ^a   Yang, Tianxin ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Acquired nephrogenic diabetes insipidus; AQP2; Collecting duct; PGE2

Indexed keywords

CYCLIC AMP; CYCLOOXYGENASE 2; LITHIUM CHLORIDE; MESSENGER RNA; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; SODIUM POTASSIUM CHLORIDE COTRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KIDNEY CORTEX; KIDNEY MEDULLA; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYURIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; URINARY EXCRETION;

EID: 71449091915     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00117.2009     Document Type: Article

References (61)

1. Anderson RJ, Berl T, McDonald KM, Schrier RW. Prostaglandins: effects on blood pressure, renal blood flow, sodium and water excretion. Kidney Int 10: 205-215, 1976.
2. Bedford JJ, Leader JP, Walker RJ. Aquaporin expression in normal human kidney and in renal disease. J Am Soc Nephrol 14: 2581-2587, 2003. (Pubitemid 37169343)
3. Bendz H, Aurell M. Drug-induced diabetes insipidus: incidence, prevention and management. Drug Saf 21: 449-456, 1999. (Pubitemid 30021101)
4. Boton R, Gaviria M, Batlle DC. Prevalence, pathogenesis, and treatment of renal dysfunction associated with chronic lithium therapy. Am J Kidney Dis 10: 329-345, 1987. (Pubitemid 17161686)
5. Breyer MD, Breyer RM. Prostaglandin E receptors and the kidney. Am J Physiol Renal Physiol 279: F12-F23, 2000.
6. Cheng X, Zhang H, Lee HL, Park JM. Cyclooxygenase-2 inhibitor preserves medullary aquaporin-2 expression and prevents polyuria after ureteral obstruction. J Urol 172: 2387-2390, 2004. (Pubitemid 39507536)
7. Christensen BM, Kim YH, Kwon TH, Nielsen S. Lithium treatment induces a marked proliferation of primarily principal cells in rat kidney inner medullary collecting duct. Am J Physiol Renal Physiol 291: F39-F48, 2006. (Pubitemid 43945934)
8. Christensen BM, Marples D, Kim YH, Wang W, Frokiaer J, Nielsen S. Changes in cellular composition of kidney collecting duct cells in rats with lithium-induced NDI. Am J Physiol Cell Physiol 286: C952-C964, 2004. (Pubitemid 38543824)
9. Christensen S, Kusano E, Yusufi AN, Murayama N, Dousa TP. Pathogenesis of nephrogenic diabetes insipidus due to chronic administration of lithium in rats. J Clin Invest 75: 1869-1879, 1985.
10. Cogan E, Abramow M. Inhibition by lithium of the hydroosmotic action of vasopressin in the isolated perfused cortical collecting tubule of the rabbit. J Clin Invest 77: 1507-1514, 1986. (Pubitemid 16047095)
11. 2, forskolin, and cholera toxin interactions in modulating NaCl transport in mouse mTALH. Am J Physiol Renal Fluid Electrolyte Physiol 247: F784-F792, 1984.
12. 1 on the permeability response of the isolated collecting tubule to vasopressin, adenosine 3′,5′- monophosphate, and theophylline. J Clin Invest 47: 1154-1161, 1968.
13. 2 inhibits AVP-induced water flow in cortical collecting ducts by protein kinase C activation. Am J Physiol Renal Fluid Electrolyte Physiol 259: F318-F325, 1990.
14. 2 inhibits sodium transport in rabbit cortical collecting duct by increasing intracellular calcium. J Clin Invest 87: 1992-1998, 1991.
15. 2 receptors modulate water and sodium transport in rabbit cortical collecting duct. Am J Physiol Renal Fluid Electrolyte Physiol 265: F643-F650, 1993.
16. Herschman HR. Prostaglandin synthase 2. Biochim Biophys Acta 1299: 125-140, 1996.
17. Jania LA, Chandrasekharan S, Backlund MG, Foley NA, Snouwaert J, Wang IM, Clark P, Audoly LP, Koller BH. Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis. Prostaglandins Other Lipid Mediat 88: 73-81, 2009.
18. Jania LA, Chandrasekharan S, Backlund MG, Foley NA, Snouwaert J, Wang IM, Clark P, Audoly LP, Koller BH. Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E(2) biosynthesis. Prostaglandins Other Lipid Mediat 88: 73-81, 2009.
19. Jensen BL, Kurtz A. Differential regulation of renal cyclooxygenase mRNA by dietary salt intake. Kidney Int 52: 1242-1249, 1997. (Pubitemid 27496053)
20. 2 protects against angiotensin II-induced hypertension via inhibition of oxidative stress. Hypertension 52: 952-959, 2008.
21. Jia Z, Zhang A, Zhang H, Dong Z, Yang T. Deletion of microsomal prostaglandin E synthase-1 increases sensitivity to salt loading and angiotensin II infusion. Circ Res 99: 1243-1251, 2006. (Pubitemid 44808661)
22. Johnston HH, Herzog JP, Lauler DP. Effect of prostaglandin E1 on renal hemodynamics, sodium and water excretion. Am J Physiol 213: 939-946, 1967.
23. Khanna A. Acquired nephrogenic diabetes insipidus. Semin Nephrol 26: 244-248, 2006.
24. Kim GH, Choi NW, Jung JY, Song JH, Lee CH, Kang CM, Knepper MA. Treating lithium-induced nephrogenic diabetes insipidus with a COX-2 inhibitor improves polyuria via upregulation of AQP2 and NKCC2. Am J Physiol Renal Physiol 294: F702-F709, 2008.
25. Kim YH, Kwon TH, Christensen BM, Nielsen J, Wall SM, Madsen KM, Frøkiær J, Nielsen S. Altered expression of renal acid-base transporters in rats with lithium-induced NDI. Am J Physiol Renal Physiol 285: F1244-F1257, 2003. (Pubitemid 37421060)
26. Klein JD, Gunn RB, Roberts BR, Sands JM. Down-regulation of urea transporters in the renal inner medulla of lithium-fed rats. Kidney Int 61: 995-1002, 2002.
27. Kotnik P, Nielsen J, Kwon TH, Krzisnik C, Frøkiær J, Nielsen S. Altered expression of COX-1, COX-2, and mPGES in rats with nephrogenic and central diabetes insipidus. Am J Physiol Renal Physiol 288: F1053-F1068, 2005. (Pubitemid 40569771)
28. + transporters in rats with lithium-induced NDI. Am J Physiol Renal Physiol 279: F552-F564, 2000.
29. Lam SS, Kjellstrand C. Emergency treatment of lithium-induced diabetes insipidus with nonsteroidal anti-inflammatory drugs. Ren Fail 19: 183-188, 1997. (Pubitemid 27082317)
30. Li Y, Shaw S, Kamsteeg EJ, Vandewalle A, Deen PM. Development of lithium-induced nephrogenic diabetes insipidus is dissociated from adenylyl cyclase activity. J Am Soc Nephrol 17: 1063-1072, 2006.
31. Lovgren AK, Kovarova M, Koller BH. cPGES/p23 is required for glucocorticoid receptor function and embryonic growth but not prostaglandin E2 synthesis. Mol Cell Biol 27: 4416-4430, 2007. (Pubitemid 46906565)
32. Marples D, Christensen S, Christensen EI, Ottosen PD, Nielsen S. Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla. J Clin Invest 95: 1838-1845, 1995.
33. Martinez EJ, Sinnott JTt Rodriguez-Paz G, Oehler RL. Lithium-induced nephrogenic diabetes insipidus treated with indomethacin. South Med J 86: 971-973, 1993. (Pubitemid 23246394)
34. Murakami M, Kudo I. Prostaglandin E synthase: a novel drug target for inflammation and cancer. Curr Pharm Des 12: 943-954, 2006.
35. 2 excretion is associated with postobstructive polyuria in human congenital hydronephrosis. J Am Soc Nephrol 15: 2705-2712, 2004.
36. 2 synthetic enzyme, are peri-natally lethal. Biochem Biophys Res Commun 362: 387-392, 2007.
37. Nally JV, Rutecki GW, Ferris TF. The acute effect of lithium on renal renin and prostaglandin E synthesis in the dog. Circ Res 46: 739-744, 1980. (Pubitemid 11213017)
38. Nejsum LN, Zelenina M, Aperia A, Frøkiær J, Nielsen S. Bidirectional regulation of AQP2 trafficking and recycling: involvement of AQP2-S256 phosphorylation. Am J Physiol Renal Physiol 288: F930-F938, 2005. (Pubitemid 40569759)
39. Nielsen J, Hoffert JD, Knepper MA, Agre P, Nielsen S, Fenton RA. Proteomic analysis of lithium-induced nephrogenic diabetes insipidus: mechanisms for aquaporin 2 down-regulation and cellular proliferation. Proc Natl Acad Sci USA 105: 3634-3639, 2008. (Pubitemid 351723604)
40. Nielsen J, Kwon TH, Christensen BM, Frøkiær J, Nielsen S. Dysregulation of renal aquaporins and epithelial sodium channel in lithium-induced nephrogenic diabetes insipidus. Semin Nephrol 28: 227-244, 2008. (Pubitemid 351749751)
41. Nielsen S, Chou CL, Marples D, Christensen EI, Kishore BK, Knepper MA. Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane. Proc Natl Acad Sci USA 92: 1013-1017, 1995.
42. Nielsen S, DiGiovanni SR, Christensen EI, Knepper MA, Harris HW. Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney. Proc Natl Acad Sci USA 90: 11663-11667, 1993. (Pubitemid 24008699)
43. Norregaard R, Jensen BL, Li C, Wang W, Knepper MA, Nielsen S, Frøkiær J. COX-2 inhibition prevents downregulation of key renal water and sodium transport proteins in response to bilateral ureteral obstruction. Am J Physiol Renal Physiol 289: F322-F333, 2005. (Pubitemid 41003662)
44. Paliege A, Mizel D, Medina C, Pasumarthy A, Huang YG, Bachmann S, Briggs JP, Schnermann JB, Yang T. Inhibition of nNOS expression in the macula densa by COX-2-derived prostaglandin E2. Am J Physiol Renal Physiol 287: F152-F159, 2004. (Pubitemid 38780594)
45. Pallone TL, Zhang Z, Rhinehart K. Physiology of the renal medullary microcirculation. Am J Physiol Renal Physiol 284: F253-F266, 2003.
46. Rao R, Hao CM, Breyer MD. Hypertonic stress activates glycogen synthase kinase 3beta-mediated apoptosis of renal medullary interstitial cells, suppressing an NFkappaB-driven cyclooxygenase-2-dependent survival pathway. J Biol Chem 279: 3949-3955, 2004. (Pubitemid 38198978)
47. Rao R, Zhang MZ, Zhao M, Cai H, Harris RC, Breyer MD, Hao CM. Lithium treatment inhibits renal GSK-3 activity and promotes cyclooxygenase 2-dependent polyuria. Am J Physiol Renal Physiol 288: F642-F649, 2005. (Pubitemid 40381730)
48. Rojek A, Nielsen J, Brooks HL, Gong H, Kim YH, Kwon TH, Frøkiær J, Nielsen S. Altered expression of selected genes in kidney of rats with lithium-induced NDI. Am J Physiol Renal Physiol 288: F1276-F1289, 2005. (Pubitemid 40677099)
49. Schneider A, Zhang Y, Zhang M, Lu WJ, Rao R, Fan X, Redha R, Davis L, Breyer RM, Harris R, Guan Y, Breyer MD. Membrane-associated PGE synthase-1 (mPGES-1) is coexpressed with both COX-1 and COX-2 in the kidney. Kidney Int 65: 1205-1213, 2004. (Pubitemid 38406958)
50. Smith WL, Garavito RM, DeWitt DL. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem 271: 33157-33160, 1996.
51. Soodvilai S, Jia Z, Wang MH, Dong Z, Yang T. mPGES-1 deletion impairs diuretic response to acute water loading. Am J Physiol Renal Physiol 296: F1129-F1135, 2009.
52. Soodvilai S, Jia Z, Yang T. Hydrogen peroxide stimulates chloride secretion in primary inner medullary collecting duct cells via mPGES-1-derived PGE2. Am J Physiol Renal Physiol 293: F1571-F1576, 2007. (Pubitemid 350085993)
53. 2 on chloride transport across the rabbit thick ascending limb of Henle. Selective inhibitions of the medullary portion. J Clin Invest 64: 495-502, 1979.
54. 2 across the isolated, perfused rabbit collecting tubule. J Clin Invest 59: 1099-1104, 1977.
55. 2, cAMP, and vasopressin in lithium-induced polyuria. Am J Physiol Regul Integr Comp Physiol 254: R863-R869, 1988.
56. Timmer RT, Sands JM. Lithium intoxication. J Am Soc Nephrol 10: 666-674, 1999.
57. Trebino CE, Stock JL, Gibbons CP, Naiman BM, Wachtmann TS, Umland JP, Pandher K, Lapointe JM, Saha S, Roach ML, Carter D, Thomas NA, Durtschi BA, McNeish JD, Hambor JE, Jakobsson PJ, Carty TJ, Perez JR, Audoly LP. Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase. Proc Natl Acad Sci USA 100: 9044-9049, 2003. (Pubitemid 36899220)
58. Walker RG. Lithium nephrotoxicity. Kidney Int Suppl 42: S93-S98, 1993.
59. Xu D, Rowland SE, Clark P, Giroux A, Cote B, Guiral S, Salem M, Ducharme Y, Friesen RW, Methot N, Mancini J, Audoly L, Riendeau D. MF63 [2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation. J Pharmacol Exp Ther 326: 754-763, 2008.
60. Yang T. Microsomal prostaglandin E synthase-1 and blood pressure regulation. Kidney Int 72: 274-278, 2007. (Pubitemid 47172379)
61. 2 interaction with AVP: effects on AQP2 phosphorylation and distribution. Am J Physiol Renal Physiol 278: F388-F394, 2000.