Maintaince of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK

European Journal of Neuroscience

Volumn 30, Issue 11, 2009, Pages 2030-2041

  Kawai, Kumi ^a,b   Itoh, Takayuki ^a,b   Itoh, Aki ^a,b   Horiuchi, Makoto ^a,b   Wakayama, Kouji ^a,b   Bannerman, Peter ^a,b   Garbern, James Y ^c   Pleasure, David ^a,b   Lindsten, Tullia ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SHRINERS HOSPITALS FOR CHILDREN NORTHERN CALIFORNIA   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Apoptosis; Aspartoacylase; Bcl 2 related protein family; Differentiation; Mouse; NG2

Indexed keywords

ASPARTOACYLASE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEOCHONDROITIN SULFATE; ANTIGEN; BAK1 PROTEIN, MOUSE; BAX PROTEIN, MOUSE; CHONDROITIN SULFATE PROTEOGLYCAN 4; GANGLIOSIDE; GANGLIOSIDE A2B5; MESSENGER RNA; MYELIN BASIC PROTEIN; O ANTIGEN; PROTEIN BCL 6; PROTEOGLYCAN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; MOUSE; NERVE FIBER; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STEM CELL; ANIMAL; BRAIN; CELL CULTURE; CELL DEATH; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; METHODOLOGY; MOUSE MUTANT; MYELIN SHEATH; NEWBORN; NICK END LABELING; OPTIC NERVE; PHYSIOLOGY; TIME;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS; APOPTOSIS; AXONS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BRAIN; CELL DEATH; CELL DIFFERENTIATION; CELLS, CULTURED; GANGLIOSIDES; GENE EXPRESSION REGULATION; IN SITU NICK-END LABELING; MICE; MICE, KNOCKOUT; MYELIN BASIC PROTEINS; MYELIN SHEATH; O ANTIGENS; OLIGODENDROGLIA; OPTIC NERVE; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS C-BCL-6; RNA, MESSENGER; STEM CELLS; TIME FACTORS;

EID: 71249156155     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2009.06988.x     Document Type: Article

References (46)

1. Barres, B.A. Raff, M.C. (1999) Axonal control of oligodendrocyte development. J. Cell Biol., 147, 1123 1128.
2. Barres, B.A., Hart, I.K., Coles, H.S., Burne, J.F., Voyvodic, J.T., Richardson, W.D. Raff, M.C. (1992) Cell death and control of cell survival in the oligodendrocyte lineage. Cell, 70, 31 46.
3. Bhat, R.V., Axt, K.J., Fosnaugh, J.S., Smith, K.J., Johnson, K.A., Hill, D.E., Kinzler, K.W. Baraban, J.M. (1996) Expression of the APC tumor suppressor protein in oligodendroglia. Glia, 17, 169 174.
4. Birchmeier, C. (2009) ErbB receptors and the development of the nervous system. Exp. Cell Res., 315, 611 618.
5. Bozzali, M. Wrabetz, L. (2004) Axonal signals and oligodendrocyte differentiation. Neurochem. Res., 29, 979 988.
6. Brunet, A., Datta, S.R. Greenberg, M.E. (2001) Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr. Opin. Neurobiol., 11, 297 305.
7. Burne, J.F., Staple, J.K. Raff, M.C. (1996) Glial cells are increased proportionally in transgenic optic nerves with increased numbers of axons. J. Neurosci., 16, 2064 2073.
8. Calver, A.R., Hall, A.C., Yu, W.P., Walsh, F.S., Heath, J.K., Betsholtz, C. Richardson, W.D. (1998) Oligodendrocyte population dynamics and the role of PDGF in vivo. Neuron, 20, 869 882.
9. Cheng, E.H., Wei, M.C., Weiler, S., Flavell, R.A., Mak, T.W., Lindsten, T. Korsmeyer, S.J. (2001) BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol. Cell, 8, 705 711.
10. Colognato, H., Baron, W., Avellana-Adalid, V., Relvas, J.B., Baron-Van Evercooren, A., Georges-Labouesse, E. ffrench-Constant, C. (2002) CNS integrins switch growth factor signalling to promote target-dependent survival. Nat. Cell Biol., 4, 833 841.
11. 6 integrin-laminin-dependent mechanism. Glia, 36, 281 294.
12. De Louw, A.J., Van Berg De, W.D., De Vente, J., Blanco, C.E., Gavilanes, A.W., Steinbusch, H.P., Steinbusch, H.W., Troost, J. Vles, J.S. (2002) Developmental apoptosis in the spinal cord white matter in neonatal rats. Glia, 37, 89 91.
13. Deckwerth, T.L., Elliott, J.L., Knudson, C.M., Johnson, E.M. Jr., Snider, W.D. Korsmeyer, S.J. (1996) BAX is required for neuronal death after trophic factor deprivation and during development. Neuron, 17, 401 411.
14. Dong, H., Fazzaro, A., Xiang, C., Korsmeyer, S.J., Jacquin, M.F. McDonald, J.W. (2003) Enhanced oligodendrocyte survival after spinal cord injury in Bax-deficient mice and mice with delayed Wallerian degeneration. J. Neurosci., 23, 8682 8691.
15. Fanarraga, M.L., Sommer, I. Griffiths, I.R. (1995) O-2A progenitors of the mouse optic nerve exhibit a developmental pattern of antigen expression different from the rat. Glia, 15, 95 104.
16. Fernandez, P.A., Tang, D.G., Cheng, L., Prochiantz, A., Mudge, A.W. Raff, M.C. (2000) Evidence that axon-derived neuregulin promotes oligodendrocyte survival in the developing rat optic nerve. Neuron, 28, 81 90.
17. Frost, E.E., Buttery, P.C., Milner, R. ffrench-Constant, C. (1999) Integrins mediate a neuronal survival signal for oligodendrocytes. Curr. Biol., 9, 1251 1254.
18. Gavrieli, Y., Sherman, Y. Ben- Sasson, S.A. (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol., 119, 493 501.
19. Green, D.R. (2000) Apoptotic pathways: paper wraps stone blunts scissors. Cell, 102, 1 4.
20. Hershfield, J.R., Madhavarao, C.N., Moffett, J.R., Benjamins, J.A., Garbern, J.Y. Namboodiri, A. (2006) Aspartoacylase is a regulated nuclear-cytoplasmic enzyme. FASEB J., 20, 2139 2141.
21. van Heyningen, P., Calver, A.R. Richardson, W.D. (2001) Control of progenitor cell number by mitogen supply and demand. Curr. Biol., 11, 232 241.
22. Horiuchi, M., Itoh, A., Pleasure, D. Itoh, T. (2006) MEK-ERK signaling is involved in interferon-γ-induced death of oligodendroglial progenitor cells. J. Biol. Chem., 281, 20095 20106.
23. Inman, D.M., Sappington, R.M., Horner, P.J. Calkins, D.J. (2006) Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma. Invest. Ophthalmol. Vis. Sci., 47, 986 996.
24. Itoh, T., Beesley, J., Itoh, A., Cohen, A.S., Kavanaugh, B., Coulter, D.A., Grinspan, J.B. Pleasure, D. (2002) AMPA glutamate receptor-mediated calcium signaling is transiently enhanced during development of oligodendrocytes. J. Neurochem., 81, 390 402.
25. Itoh, T., Itoh, A. Pleasure, D. (2003) Bcl-2-related protein family gene expression during oligodendroglial differentiation. J. Neurochem., 85, 1500 1512.
26. Knudson, C.M., Tung, K.S., Tourtellotte, W.G., Brown, G.A. Korsmeyer, S.J. (1995) Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science, 270, 96 99.
27. Laursen, L.S. ffrench-Constant, C. (2007) Adhesion molecules in the regulation of CNS myelination. Neuron Glia Biol., 3, 367 375.
28. Lindsten, T., Ross, A.J., King, A., Zong, W.X., Rathmell, J.C., Shiels, H.A., Ulrich, E., Waymire, K.G., Mahar, P., Frauwirth, K., Chen, Y., Wei, M., Eng, V.M., Adelman, D.M., Simon, M.C., Ma, A., Golden, J.A., Evan, G., Korsmeyer, S.J., MacGregor, G.R. Thompson, C.B. (2000) The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues. Mol. Cell, 6, 1389 1399.
29. Lindsten, T., Golden, J.A., Zong, W.X., Minarcik, J., Harris, M.H. Thompson, C.B. (2003) The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool. J. Neurosci., 23, 11112 11119.
30. Lindsten, T., Zong, W.X. Thompson, C.B. (2005) Defining the role of the Bcl-2 family of proteins in the nervous system. Neuroscientist, 11, 10 15.
31. Madhavarao, C.N., Moffett, J.R., Moore, R.A., Viola, R.E., Namboodiri, M.A. Jacobowitz, D.M. (2004) Immunohistochemical localization of aspartoacylase in the rat central nervous system. J. Comp. Neurol., 472, 318 329.
32. McBride, C.B., McPhail, L.T., Vanderluit, J.L., Tetzlaff, W. Steeves, J.D. (2003) Caspase inhibition attenuates transection-induced oligodendrocyte apoptosis in the developing chick spinal cord. Mol. Cell. Neurosci., 23, 383 397.
33. McKinnon, R.D., Waldron, S. Kiel, M.E. (2005) PDGF α-receptor signal strength controls an RTK rheostat that integrates phosphoinositol 3′-kinase and phospholipase Cγ pathways during oligodendrocyte maturation. J. Neurosci., 25, 3499 3508.
34. Miller, R.H. (2002) Regulation of oligodendrocyte development in the vertebrate CNS. Prog. Neurobiol., 67, 451 467.
35. Nave, K.A. Trapp, B.D. (2008) Axon-glial signaling and the glial support of axon function. Annu. Rev. Neurosci., 31, 535 561.
36. Nishiyama, A., Komitova, M., Suzuki, R. Zhu, X. (2009) Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity. Nat. Rev. Neurosci., 10, 9 22.
37. Polito, A. Reynolds, R. (2005) NG2-expressing cells as oligodendrocyte progenitors in the normal and demyelinated adult central nervous system. J. Anat., 207, 707 716.
38. Puthalakath, H. Strasser, A. (2002) Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ., 9, 505 512.
39. See, J.M. Grinspan, J.B. (2009) Sending mixed signals: bone morphogenetic protein in myelination and demyelination. J. Neuropathol. Exp. Neurol., 68, 595 604.
40. Stallcup, W.B. (2002) The NG2 proteoglycan: past insights and future prospects. J. Neurocytol., 31, 423 435.
41. Tansey, F.A. Cammer, W. (1991) A pi form of glutathione-S-transferase is a myelin- and oligodendrocyte-associated enzyme in mouse brain. J. Neurochem., 57, 95 102.
42. Trapp, B.D., Nishiyama, A., Cheng, D. Macklin, W. (1997) Differentiation and death of premyelinating oligodendrocytes in developing rodent brain. J. Cell Biol., 137, 459 468.
43. Vartanian, T., Fischbach, G. Miller, R. (1999) Failure of spinal cord oligodendrocyte development in mice lacking neuregulin. Proc. Natl Acad. Sci. USA, 96, 731 735.
44. Wang, S., Sdrulla, A., Johnson, J.E., Yokota, Y. Barres, B.A. (2001) A role for the helix-loop-helix protein Id2 in the control of oligodendrocyte development. Neuron, 29, 603 614.
45. Wei, M.C., Zong, W.X., Cheng, E.H., Lindsten, T., Panoutsakopoulou, V., Ross, A.J., Roth, K.A., MacGregor, G.R., Thompson, C.B. Korsmeyer, S.J. (2001) Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science, 292, 727 730.
46. White, F.A., Keller- Peck, C.R., Knudson, C.M., Korsmeyer, S.J. Snider, W.D. (1998) Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J. Neurosci., 18, 1428 1439.