ErbB receptors and the development of the nervous system

Experimental Cell Research

Volumn 315, Issue 4, 2009, Pages 611-618

  Birchmeier, Carmen ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

ErbB receptors; Nervous system development; Neural crest; Nrg1; Schizophrenia

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; NEU DIFFERENTIATION FACTOR; ONCOPROTEIN;

ANIMAL; CELL MOTION; CLASSIFICATION; GROWTH, DEVELOPMENT AND AGING; HUMAN; MENTAL DISEASE; METABOLISM; NERVOUS SYSTEM; PATHOPHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CELL MOVEMENT; HUMANS; MENTAL DISORDERS; NERVOUS SYSTEM; NEUREGULIN-1; ONCOGENE PROTEINS V-ERBB; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 62649106306     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2008.10.035     Document Type: Review

References (70)

1. B. Vennstrom, J.M. Bishop, Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus, Cell 28 (1982) 135-143.
2. J. Downward, Y. Yarden, E. Mayes, G. Scrace, N. Totty, P. Stockwell, A. Ullrich, J. Schlessinger, M.D. Waterfield, Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences, Nature 307 (1984) 521-527.
3. A. Buonanno, G.D. Fischbach, Neuregulin and ErbB receptor signaling pathways in the nervous system, Curr. Opin. Neurobiol. 11 (2001) 287-296.
4. Y. Yarden, M.X. Sliwkowski, Untangling the ErbB signalling network, Nat. Rev. Mol. Cell Biol. 2 (2001) 127-137.
5. D.L. Falls, Neuregulins: functions, forms, and signaling strategies, Exp. Cell Res. 284 (2003) 14-30.
6. D.L. Falls, K.M. Rosen, G. Corfas, W.S. Lane, G.D. Fischbach, ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family, Cell 72 (1993) 801-815.
7. W.E. Holmes, M.X. Sliwkowski, R.W. Akita,W.J. Henzel, J. Lee, J.W. Park, D. Yansura, N. Abadi, H. Raab, G.D. Lewis, et al., Identificationof heregulin, a specific activator of p185erbB2, Science 256 (1992) 1205-1210.
8. M.A. Marchionni, A.D. Goodearl, M.S. Chen, M.O. Bermingham, C. Kirk,M. Hendricks, F. Danehy, D.Misumi, J. Sudhalter, K. Kobayashi, et al., Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system, Nature 362 (1993) 312-318.
9. D. Wen, E. Peles, R. Cupples, S.V. Suggs, S.S. Bacus, Y. Luo, G. Trail, S. Hu, S.M. Silbiger, R.B. Levy, et al., Neu differentiation factor: a transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit, Cell 69 (1992) 559-572.
10. J. Schlessinger, Ligand-induced, receptor-mediated dimerization and activation of EGF receptor, Cell 110 (2002) 669-672.
11. J. Bao, D. Wolpowitz, L.W. Role, D.A. Talmage, Back signaling by the Nrg-1 intracellular domain, J. Cell Biol. 161 (2003) 1133-1141.
12. C.Y. Ni, M.P. Murphy, T.E. Golde, G. Carpenter, gamma-Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase, Science 294 (2001) 2179-2181.
13. S.P. Sardi, J. Murtie, S. Koirala, B.A. Patten, G. Corfas, Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain, Cell 127 (2006) 185-197.
14. D. Meyer, C. Birchmeier, Multiple essential functions of neuregulin in development. Nature 378 (1995) 386-390.
15. K.F. Lee, H. Simon, H. Chen, B. Bates, M.C. Hung, C. Hauser, Requirement for neuregulin receptor erbB2 in neural and cardiac development, Nature 378 (1995) 394-398.
16. A. Citri, K.B. Skaria, Y. Yarden, The deaf and the dumb: the biology of ErbB-2 and ErbB-3, Exp. Cell Res. 284 (2003) 54-65.
17. E. Peles, L.R. Ben, E. Tzahar, N. Liu, D. Wen, Y. Yarden, Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships, EMBO J. 12 (1993) 961-971.
18. K.R. Carraway, L.C. Cantley, A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling, Cell 78 (1994) 5-8.
19. G.D. Plowman, J.M. Green, J.M. Culouscou, G.W. Carlton, V.M. Rothwell, S. Buckley, Heregulin induces tyrosine phosphorylation of HER4/p180erbB4, Nature 366 (1993) 473-475.
20. A.N. Garratt, S. Britsch, C. Birchmeier, Neuregulin, a factor with many functions in the life of a Schwann cell, BioEssays 22 (2000) 987-996.
21. N.M. Le Douarin, S. Creuzet, G. Couly, E. Dupin, Neural crest cell plasticity and its limits, Development 131 (2004) 4637-4650.
22. D.J. Anderson, Cellular and molecular biology of neural crest cell lineage determination, Trends Genet. 13 (1997) 276-280.
23. A.K. Groves, M. Bronner-Fraser, Neural crest diversification, Curr. Top. Dev. Biol. 43 (1999) 221-258.
24. J.F. Crane, P.A. Trainor, Neural crest stem and progenitor cells, Annu. Rev. Cell Dev. Biol. 22 (2006) 267-286.
25. D. Meyer, T. Yamaai, A.N. Garratt, E. Riethmacher-Sonnenberg, D. Kane, L. Theill, C. Birchmeier, Isoform specific expression and function of neuregulin. Development 124 (1997) 3575-3586.
26. S. Britsch, L. Li, S. Kirchhoff, F. Theuring, V. Brinkmann, C. Birchmeier, D. Riethmacher, The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system, Genes Dev. 12 (1998) 1825-1836.
27. K.R. Jessen, R. Mirsky, The origin and development of glial cells in peripheral nerves, Nat. Rev. Neurosci. 6 (2005) 671-682.
28. J.P. Brockes, G.E. Lemke, D.R. Balzer Jr., Purification and preliminary characterization of a glial growth factor from the bovine pituitary, J. Biol. Chem. 255 (1980) 8374-8377.
29. G.E. Lemke, J.P. Brockes, Identification and purification of glial growth factor, J. Neurosci. 4 (1984) 75-83.
30. D. Riethmacher, E. Sonnenberg-Riethmacher, V. Brinkmann, T. Yamaai, G.R. Lewin, C. Birchmeier, Severe neuropathies in mice with targeted mutations in the ErbB3 receptor, Nature 389 (1997) 725-730.
31. Y. Honjo, J. Kniss, J.S. Eisen, Neuregulin-mediated ErbB3 signaling is required for formation of zebrafish dorsal root ganglion neurons, Development 135 (2008) 2615-2625.
32. D.A. Lyons, H.M. Pogoda, M.G. Voas, I.G. Woods, B. Diamond, R. Nix, N. Arana, J. Jacobs, W.S. Talbot, erbb3 and erbb2 are essential for Schwann cell migration and myelination in zebrafish, Curr. Biol. 15 (2005) 513-524.
33. H.H. Donaldson, G.W. Hoke, On the areas of the axis cylinder and medullary sheath as seen in cross sections of the spinal nerves of vertebrates, J. Comp. Neurol. 15 (1905) 1-16.
34. R. Nagarajan, N. Le, H. Mahoney, T. Araki, J. Milbrandt, Deciphering peripheral nerve myelination by using Schwann cell expression profiling, Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 8998-9003.
35. M.H. Verheijen, R. Chrast, P. Burrola,G. Lemke, Local regulation of fat metabolismin peripheral nerves, Genes Dev. 17 (2003) 2450-2464.
36. A.N. Garratt, O. Voiculescu, P. Topilko, P. Charnay, C. Birchmeier, A dual role of erbB2 in myelination and in expansion of the Schwann cell precursor pool, J. Cell Biol. 148 (2000) 1035-1046.
37. G.V. Michailov, M.W. Sereda, B.G. Brinkmann, T.M. Fischer, B. Haug, C. Birchmeier, L. Role, C. Lai, M.H. Schwab, K.A. Nave, Axonal neuregulin-1 regulates myelin sheath thickness, Science 304 (2004) 700-703.
38. C. Taveggia, G. Zanazzi, A. Petrylak, H. Yano, J. Rosenbluth, S. Einheber, X. Xu, R.M. Esper, J.A. Loeb, P. Shrager, M.V. Chao, D.L. Falls, L. Role, J.L. Salzer, Neuregulin-1 type III determines the ensheathment fate of axons, Neuron 47 (2005) 681-694.
39. K. Roy, J.C. Murtie, B.F. El-Khodor, N. Edgar, S.P. Sardi, B.M. Hooks, M. Benoit-Marand, C. Chen, H. Moore, P. O'Donnell, D. Brunner, G. Corfas, Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders, Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 8131-8136.
40. J. Schmucker, M. Ader, D. Brockschnieder, A. Brodarac, U. Bartsch, D. Riethmacher, erbB3 is dispensable for oligodendrocyte development in vitro and in vivo, Glia 44 (2003) 67-75.
41. C.R. Sussman, T. Vartanian, R.H. Miller, The ErbB4 neuregulin receptor mediates suppression of oligodendrocyte maturation, J. Neurosci. 25 (2005) 5757-5762.
42. C. Taveggia, P. Thaker, A. Petrylak, G.L. Caporaso, A. Toews, D.L. Falls, S. Einheber, J.L. Salzer, Type III neuregulin-1 promotes oligodendrocyte myelination, Glia 56 (2008) 284-293.
43. B.G. Brinkmann, A. Agarwal, M.W. Sereda, A.N. Garratt, T. Müller, W. Wende, R.M. Stassart, S. Nawaz, C. Humml, V. Velanac, K. Radyuschkin, S. Goebbels, T.M. Fischer, R.J. Franklin, C. Lai, H. Ehrenreich, C. Birchmeier, M.H. Schwab, K.A. Nave, Neuregulin-1/ ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system, Proc. Neuron 59 (4) (2008) 581-595.
44. J.Y. Wang, S.J. Miller, D.L. Falls, The N-terminal region of neuregulin isoforms determines the accumulation of cell surface and released neuregulin ectodomain, J. Biol. Chem. 276 (2001) 2841-2851.
45. S. Hippenmeyer, N.A. Shneider, C. Birchmeier, S.J. Burden, T.M. Jessell, S. Arber, A role for neuregulin1 signaling in muscle spindle differentiation, Neuron 36 (2002) 1035-1049.
46. I. Hussain, D. Powell, D.R. Howlett, D.G. Tew, T.D. Meek, C. Chapman, I.S. Gloger, K.E. Murphy, C.D. Southan, D.M. Ryan, T.S. Smith, D.L. Simmons, F.S. Walsh, C. Dingwall, G. Christie, Identification of a novel aspartic protease (Asp 2) as beta-secretase, Mol. Cell. Neurosci. 14 (1999) 419-427.
47. X. Lin, G. Koelsch, S. Wu, D. Downs, A. Dashti, J. Tang, Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein, Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 1456-1460.
48. S. Sinha, I. Lieberburg, Cellular mechanisms of beta-amyloid production and secretion, Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 11049-11053.
49. R. Vassar, B.D. Bennett, S. Babu-Khan, S. Kahn, E.A. Mendiaz, P. Denis, D.B. Teplow, S. Ross, P. Amarante, R. Loeloff, Y. Luo, S. Fisher,J. Fuller, S. Edenson, J. Lile, M.A. Jarosinski, A.L. Biere, E. Curran, T. Burgess, J.C. Louis, F. Collins, J. Treanor, G. Rogers, M. Citron, Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE, Science 286 (1999) 735-741.
50. R. Yan, M.J. Bienkowski, M.E. Shuck, H. Miao, M.C. Tory, A.M. Pauley, J.R. Brashier, N.C. Stratman, W.R. Mathews, A.E. Buhl, D.B. Carter, A.G. Tomasselli, L.A. Parodi, R.L. Heinrikson, M.E. Gurney, Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity, Nature 402 (1999) 533-537.
51. X. Hu, C.W. Hicks,W. He, P.Wong,W.B. Macklin, B.D. Trapp, R. Yan, Bace1 modulates myelination in the central and peripheral nervous system, Nat. Neurosci. 9 (2006) 1520-1525.
52. M. Willem, A.N. Garratt, B. Novak, M. Citron, S. Kaufmann, A. Rittger, B. DeStrooper, P. Saftig, C. Birchmeier, C. Haass, Control of peripheral nerve myelination by the beta-secretase BACE1, Science 314 (2006) 664-666.
53. M. Bjarnadottir, D.L. Misner, S. Haverfield-Gross, S. Bruun, V.G. Helgason, H. Stefansson, A. Sigmundsson, D.R. Firth, B. Nielsen, R. Stefansdottir, T.J. Novak, K. Stefansson, M.E. Gurney, T. Andresson, Neuregulin1 (NRG1) signaling through Fyn modulates NMDA receptor phosphorylation: differential synaptic function in NRG1+/- knock-outs compared with wild-type mice, J. Neurosci. 27 (2007) 4519-4529.
54. P.J. Harrison, A.J. Law, Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology, Biol. Psychiatry 60 (2006) 132-140.
55. O.B. Kwon, M. Longart, D. Vullhorst, D.A. Hoffman, A. Buonanno, Neuregulin-1 reverses long-term potentiation at CA1 hippocampal synapses, J. Neurosci. 25 (2005) 9378-9383.
56. B. Li, R.S. Woo, L. Mei, R. Malinow, The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity, Neuron 54 (2007) 583-597.
57. L.W. Role, D.A. Talmage, Neurobiology: new order for thought disorders, Nature 448 (2007) 263-265.
58. A.J. Law, B.K. Lipska, C.S. Weickert, T.M. Hyde, R.E. Straub, R. Hashimoto, P.J. Harrison, J.E. Kleinman, D.R. Weinberger, Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the disease, Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 6747-6752.
59. H. Stefansson, E. Sigurdsson, V. Steinthorsdottir, S. Bjornsdottir, T. Sigmundsson, S. Ghosh, J. Brynjolfsson, S. Gunnarsdottir, O. Ivarsson, T.T. Chou, O. Hjaltason, B. Birgisdottir, H. Jonsson, V.G. Gudnadottir, E. Gudmundsdottir, A. Bjornsson, B. Ingvarsson, A. Ingason, S. Sigfusson, H. Hardardottir, R.P. Harvey, D. Lai, M. Zhou, D. Brunner, V. Mutel, A. Gonzalo, G. Lemke, J. Sainz, G. Johannesson, T. Andresson, D. Gudbjartsson, A. Manolescu, M.L. Frigge, M.E. Gurney, A. Kong, J.R. Gulcher, H. Petursson, K. Stefansson, Neuregulin 1 and susceptibility to schizophrenia, Am. J. Hum. Genet. 71 (2002) 877-892.
60. A.V. Savonenko, T. Melnikova, F.M. Laird, K.A. Stewart, D.L. Price, P.C. Wong, Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice, Proc. Natl. Acad. Sci. U.S.A. 105 (2008) 5585-5590.
61. J.C. Montero, L. Yuste, E. Diaz-Rodriguez, A. Esparis-Ogando, A. Pandiella, Differential shedding of transmembrane neuregulin isoforms by the tumor necrosis factor-alpha-converting enzyme, Mol. Cell. Neurosci. 16 (2000) 631-648.
62. K. Shirakabe, S. Wakatsuki, T. Kurisaki, A. Fujisawa-Sehara, Roles of Meltrin beta/ADAM19 in the processing of neuregulin, J. Biol. Chem. 276 (2001) 9352-9358.
63. N. Flames, J.E. Long, A.N. Garratt, T.M. Fischer, M. Gassmann, C. Birchmeier, C. Lai, J.L. Rubenstein, O. Marin, Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1, Neuron 44 (2004) 251-261.
64. G. Lopez-Bendito, A. Cautinat, J.A. Sanchez, F. Bielle, N. Flames, A.N. Garratt, D.A. Talmage, L.W. Role, P. Charnay, O. Marin, S. Garel, Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation, Cell 125 (2006) 127-142.
65. M. Gassmann, F. Casagranda, D. Orioli, H. Simon, C. Lai, R. Klein, G. Lemke, Aberrant neural and cardiac development in mice lacking the erbB4 neuregulin receptor, Nature 378 (1995) 390-394.
66. E.S. Anton, H.T. Ghashghaei, J.L. Weber, C. McCann, T.M. Fischer, I.D. Cheung, M. Gassmann, A. Messing, R. Klein, M.H. Schwab, K.C. Lloyd, C. Lai, Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain, Nat. Neurosci. 7 (2004) 1319-1328.
67. P.J. Harrison, Schizophrenia susceptibility genes and their neurodevelopmental implications: focus on neuregulin 1, Novartis Found. Symp. 288 (2007) 246-255 discussion 255-249, 276-281.
68. Y. Liu, B. Ford, M.A. Mann, G.D. Fischbach, Neuregulins increase alpha7 nicotinic acetylcholine receptors and enhance excitatory synaptic transmission in GABAergic interneurons of the hippocampus, J. Neurosci. 21 (2001) 5660-5669.
69. X. Yang, Y. Kuo, P. Devay, C. Yu, L. Role, A cysteine-rich isoform of neuregulin controls the level of expression of neuronal nicotinic receptor channels during synaptogenesis,Neuron 20 (1998) 255-270.
70. Y.J. Chen, M.A. Johnson, M.D. Lieberman, R.E. Goodchild, S. Schobel, N. Lewandowski, G. Rosoklija, R.C. Liu, J.A. Gingrich, S. Small, H. Moore, A.J. Dwork, D.A. Talmage, L.W. Role, Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components, J. Neurosci. 28 (2008) 6872-6883.