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Volumn 10, Issue 12, 2009, Pages 1346-1358

Alpharadin, a 223Ra-based α-particle-emitting pharmaceutical for the treatment of bone metastases in patients with cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; ALPHARADIN RA 223; HEMOGLOBIN; PAMIDRONIC ACID; PLACEBO; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; RADIUM;

EID: 71249088083     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (55)

References (187)
  • 2
    • 0023795019 scopus 로고
    • Migration and phenotypic transformation of osteoclast precursors into mature osteoclasts: The effect of a bisphosphonate
    • 82349
    • 82349 Migration and phenotypic transformation of osteoclast precursors into mature osteoclasts: The effect of a bisphosphonate. Lowik CW, van der Pluij M, van der Weepals LJ, van de Groot HB, Bijvoet OL J BONE MINER RES 1988 3 2 185-192
    • (1988) Bijvoet OL J BONE MINER RES , vol.3 , Issue.2 , pp. 185-192
    • Lowik, C.W.1    Van Der Pluij, M.2    Van Der Weepals, L.J.3    Van De Groot, H.B.4
  • 3
    • 0027532535 scopus 로고
    • Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer
    • 121725 Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer. Yagoda A, Petrylak D CANCER 1993 71 3 1098-1109 (Pubitemid 23049638)
    • (1993) Cancer , vol.71 , Issue.SUPPL.3 , pp. 1098-1109
    • Yagoda, A.1    Petrylak, D.2
  • 8
    • 0027386829 scopus 로고
    • Targeted radionuclide therapy for bone metastases
    • 194395
    • 194395 Targeted radionuclide therapy for bone metastases. Lewington VJ EUR J NUCL MED 1993 20 1 66-74
    • (1993) EUR J NUCL MED , vol.20 , Issue.1 , pp. 66-74
    • Lewington, V.J.1
  • 9
    • 0023063174 scopus 로고
    • 153Sm-EDTMP and 186Re-HEDP as bone therapeutic radiopharmaceuticals
    • 194421
    • 194421 153Sm-EDTMP and 186Re-HEDP as bone therapeutic radiopharmaceuticals. Ketring AR NUCL MED BIOL 1987 14 3 223-232
    • (1987) NUCL MED BIOL , vol.14 , Issue.3 , pp. 223-232
    • Ketring, A.R.1
  • 10
    • 0029125508 scopus 로고
    • Docetaxel
    • 196204
    • 196204 Docetaxel. Cortes JE, Pazdur R J CLIN ONCOL 1995 13 10 2643-2655
    • (1995) J CLIN ONCOL , vol.13 , Issue.10 , pp. 2643-2655
    • Cortes, J.E.1    Pazdur, R.2
  • 11
    • 0023875466 scopus 로고
    • Re-186(Sn) HEDP for treatment of multiple metastatic foci in bone: Human biodistribution and dosimetric studies
    • 216620
    • 216620 Re-186(Sn) HEDP for treatment of multiple metastatic foci in bone: Human biodistribution and dosimetric studies. Maxon HR, Deutsch EA, Thomas SR, Libson K, Lukes SJ, Williams CC, Ali S RADIOLOGY 1988 166 2 501-507
    • (1988) RADIOLOGY , vol.166 , Issue.2 , pp. 501-507
    • Maxon, H.R.1    Deutsch, E.A.2    Thomas, S.R.3    Libson, K.4    Lukes, S.J.5    Williams, C.C.6    Ali, S.7
  • 12
    • 0029782630 scopus 로고    scopus 로고
    • Delay in progression of bone metastases in breast cancer patients treated with intravenous pamidronate: Results from a multinational randomized controlled trial
    • 278014
    • 278014 Delay in progression of bone metastases in breast cancer patients treated with intravenous pamidronate: Results from a multinational randomized controlled trial. Conte PF, Latreille J, Mauriac L, Calabresi R, Santos R, Campos D, Bonneterre J, Francini G, Ford JM J CLIN ONCOL 1996 14 9 2552-2559
    • (1996) J CLIN ONCOL , vol.14 , Issue.9 , pp. 2552-2559
    • Conte, P.F.1    Latreille, J.2    Mauriac, L.3    Calabresi, R.4    Santos, R.5    Campos, D.6    Bonneterre, J.7    Francini, G.8    Ford, J.M.9
  • 13
    • 0030826872 scopus 로고    scopus 로고
    • Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices
    • 359250
    • 359250 Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices. Boissier S, Magnetto S, Frappart L, Cuzin B, Ebetino FH, Delmas PD, Clezardin P CANCER RES 1997 57 18 3890-3894
    • (1997) CANCER RES , vol.57 , Issue.18 , pp. 3890-3894
    • Boissier, S.1    Magnetto, S.2    Frappart, L.3    Cuzin, B.4    Ebetino, F.H.5    Delmas, P.D.6    Clezardin, P.7
  • 16
    • 0022648104 scopus 로고
    • Stimulation of bone-resorption and inhibition of bone-formation in vitro by human-tumor necrosis factors
    • 425483
    • 425483 Stimulation of bone-resorption and inhibition of bone-formation in vitro by human-tumor necrosis factors. Bertolini DR, Nedwin GE, Bringman TS, Smith DD, Mundy GR NATURE 1986 319 6053 516-518
    • (1986) NATURE , vol.319 , Issue.6053 , pp. 516-518
    • Bertolini, D.R.1    Nedwin, G.E.2    Bringman, T.S.3    Smith, D.D.4    Mundy, G.R.5
  • 19
    • 0036060493 scopus 로고    scopus 로고
    • State-of-the-art treatment of metastatic hormonerefractory prostate cancer
    • 503127
    • 503127 State-of-the-art treatment of metastatic hormonerefractory prostate cancer. Goodin S, Rao KV, DiPaola RS ONCOLOGIST 2002 7 4 360-370
    • (2002) ONCOLOGIST , vol.7 , Issue.4 , pp. 360-370
    • Goodin, S.1    Rao, K.V.2    Dipaola, R.S.3
  • 20
    • 0033783227 scopus 로고    scopus 로고
    • Bisphosphonates induce breast cancer cell death in vitro
    • 537259
    • 537259 Bisphosphonates induce breast cancer cell death in vitro. Fromigue O, Lagneaux L, Body JJ J BONE MINER RES 2000 15 11 2211-2221
    • (2000) J BONE MINER RES , vol.15 , Issue.11 , pp. 2211-2221
    • Fromigue, O.1    Lagneaux, L.2    Body, J.J.3
  • 23
    • 35648968713 scopus 로고    scopus 로고
    • A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer
    • 853313
    • 853313 A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer. Carducci MA, Saad F, Abrahamsson PA, Dearnaley DR, Schulman CC, North SA, Sleep DJ, Isaacson JD, Nelson JB CANCER 2007 110 9 1959-1966
    • (2007) CANCER , vol.110 , Issue.9 , pp. 1959-1966
    • Carducci, M.A.1    Saad, F.2    Abrahamsson, P.A.3    Dearnaley, D.R.4    Schulman, C.C.5    North, S.A.6    Sleep, D.J.7    Isaacson, J.D.8    Nelson, J.B.9
  • 25
    • 84883155001 scopus 로고    scopus 로고
    • Cellular effects of ? particle radiation from radium-223: Alpharadin, a new radiopharmaceutical for the treatment of skeletal metastases
    • 896293 April 16
    • 896293 Cellular effects of ? particle radiation from radium-223: Alpharadin, a new radiopharmaceutical for the treatment of skeletal metastases. Dornish M, Heier-Baardson H, Pettersen EO AM ASSOC CANCER RES ANN MEET 2008 99 April 16 Abs 5749
    • (2008) AM ASSOC CANCER RES ANN MEET , vol.99
    • Dornish, M.1    Heier-Baardson, H.2    Pettersen, E.O.3
  • 26
    • 71249155655 scopus 로고    scopus 로고
    • A biodistribution and dosimetry study of therapeutic 223Ra-chloride (Alpharadin) in patients with osteoblastic skeletal metastases secondary to hormone refractory prostate cancer
    • 916972 55th June 18th
    • 916972 A biodistribution and dosimetry study of therapeutic 223Ra-chloride (Alpharadin) in patients with osteoblastic skeletal metastases secondary to hormone refractory prostate cancer. Hindorf C, Flux GD, Lewington V, Aksnes AK, Harris P, Parker C ABS SOC NUCLEAR MED ANN MEET 2008 55th June 18th Abs 576
    • (2008) ABS SOC NUCLEAR MED ANN MEET
    • Hindorf, C.1    Flux, G.D.2    Lewington, V.3    Aksnes, A.K.4    Harris, P.5    Parker, C.6
  • 27
    • 71249148177 scopus 로고    scopus 로고
    • Algeta begins first US clinical trial of Alpharadin in men with advanced prostate cancer
    • 934422 August 12
    • 934422 Algeta begins first US clinical trial of Alpharadin in men with advanced prostate cancer. Algeta ASA PRESS RELEASE 2008 August 12
    • (2008) Algeta ASA PRESS RELEASE
  • 28
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • 945461
    • 945461 Metastasis to bone: Causes, consequences and therapeutic opportunities. Mundy GR NAT REV CANCER 2002 2 8 584-593
    • (2002) NAT REV CANCER , vol.2 , Issue.8 , pp. 584-593
    • Mundy, G.R.1
  • 29
    • 20644447798 scopus 로고    scopus 로고
    • First clinical experience with ?-emitting radium-223 in the treatment of skeletal metastases
    • 976057 Pain palliation was observed in the majority of patients, and BAP levels were decreased by 52.1 and 29.5% from baseline in the prostate and breast cancer groups, respectively. Accumulation of the drug was observed in the bone metastases. Hematological DLTs were not observed
    • 976057 First clinical experience with ?-emitting radium-223 in the treatment of skeletal metastases. Nilsson S, Larsen RH, Fossa SD, Balteskard L, Borch KW, Westlin JE, Salberg G, Bruland OS CLIN CANCER RES 2005 11 12 4451-4459 Pain palliation was observed in the majority of patients, and BAP levels were decreased by 52.1 and 29.5% from baseline in the prostate and breast cancer groups, respectively. Accumulation of the drug was observed in the bone metastases. Hematological DLTs were not observed.
    • (2005) CLIN CANCER RES , vol.11 , Issue.12 , pp. 4451-4459
    • Nilsson, S.1    Larsen, R.H.2    Fossa, S.D.3    Balteskard, L.4    Borch, K.W.5    Westlin, J.E.6    Salberg, G.7    Bruland, O.S.8
  • 30
    • 0037315930 scopus 로고    scopus 로고
    • Targeting of osseous sites with ?-emitting 223Ra: Comparison with the ?-emitter 89Sr in mice
    • 976058
    • 976058 Targeting of osseous sites with ?-emitting 223Ra: Comparison with the ?-emitter 89Sr in mice. Henriksen G, Fisher DR, Roeske JC, Bruland OS, Larsen RH J NUCL MED 2003 44 2 252-259
    • (2003) J NUCL MED , vol.44 , Issue.2 , pp. 252-259
    • Henriksen, G.1    Fisher, D.R.2    Roeske, J.C.3    Bruland, O.S.4    Larsen, R.H.5
  • 31
    • 0034768348 scopus 로고    scopus 로고
    • 223Ra for endoradiotherapeutic applications prepared from an immobilized 227Ac/227Th source
    • 976059
    • 976059 223Ra for endoradiotherapeutic applications prepared from an immobilized 227Ac/227Th source. Henriksen G, Alstad J, Hoff P, Larsen RH RADIOCHIMICA ACTA 2001 89 10 661-666
    • (2001) RADIOCHIMICA ACTA , vol.89 , Issue.10 , pp. 661-666
    • Henriksen, G.1    Alstad, J.2    Hoff, P.3    Larsen, R.H.4
  • 32
    • 0036606104 scopus 로고    scopus 로고
    • Significant antitumor effect from bone-seeking, ?-particle-emitting 223Ra demonstrated in an experimental skeletal metastases model
    • 976065 Bone marrow retention was low compared with bone matrix retention
    • 976065 Significant antitumor effect from bone-seeking, ?-particle-emitting 223Ra demonstrated in an experimental skeletal metastases model. Henriksen G, Breistol K, Bruland OS, Fodstad O, Larsen RH CANCER RES 2002 62 11 3120-3125 Bone marrow retention was low compared with bone matrix retention.
    • (2002) CANCER RES , vol.62 , Issue.11 , pp. 3120-3125
    • Henriksen, G.1    Breistol, K.2    Bruland, O.S.3    Fodstad, O.4    Larsen, R.H.5
  • 34
    • 33750701925 scopus 로고    scopus 로고
    • Bone-seeking radium-223 adjuvant to external beam radiotherapy demonstrates significant decline in bone-alkaline phosphatase and PSA in patients with hormone refractory prostate cancer (HRPC)
    • 976072
    • 976072 Bone-seeking radium-223 adjuvant to external beam radiotherapy demonstrates significant decline in bone-alkaline phosphatase and PSA in patients with hormone refractory prostate cancer (HRPC). Nilsson S, Franzen L, Tyrrell C, Blom R, Tennvall J, Lennernas B, Yachnin J, Johannessen DC, Sokal M, Bruland OS ASCO PROSTATE CANCER SYMP 2006 Abs 215
    • (2006) ASCO PROSTATE CANCER SYMP
    • Nilsson, S.1    Franzen, L.2    Tyrrell, C.3    Blom, R.4    Tennvall, J.5    Lennernas, B.6    Yachnin, J.7    Johannessen, D.C.8    Sokal, M.9    Bruland, O.S.10
  • 36
    • 71249135266 scopus 로고    scopus 로고
    • Radium-223 in the treatment of metastatic hormone refractory prostate cancer (HRPC): Results from a randomized, placebo-controlled, phase II study
    • 976075
    • 976075 Radium-223 in the treatment of metastatic hormone refractory prostate cancer (HRPC): Results from a randomized, placebo-controlled, phase II study. Nilsson S, Franzen L, Tyrrell C, Blom R, Tennvall J, Lennernas B, Johannessen DC, Sokal M, Parker C, Bruland OS J CLIN ONCOL 2007 25 18 Suppl Abs 5071
    • (2007) Bruland OS J CLIN ONCOL , vol.25 , Issue.18 SUPPL.
    • Nilsson, S.1    Franzen, L.2    Tyrrell, C.3    Blom, R.4    Tennvall, J.5    Lennernas, B.6    Johannessen, D.C.7    Sokal, M.8    Parker, C.9
  • 39
    • 71249101681 scopus 로고    scopus 로고
    • Algeta completes comprehensive phase II clinical program with Alpharadin for treating bone metastases in patients with advanced prostate cancer
    • 976410 January 14
    • 976410 Algeta completes comprehensive phase II clinical program with Alpharadin for treating bone metastases in patients with advanced prostate cancer. Algeta ASA PRESS RELEASE 2009 January 14
    • (2009) Algeta ASA PRESS RELEASE
  • 41
    • 71249114854 scopus 로고    scopus 로고
    • Tolerability of a novel bone-seeking radionuclide - The ? emitter radium-223 - In patients with skeletal metastases from breast and prostate cancer
    • 978475
    • 978475 Tolerability of a novel bone-seeking radionuclide - the ? emitter radium-223 - in patients with skeletal metastases from breast and prostate cancer. Nilsson S, Balteskard L, Fossa SD, Westlin J-E, Borch K, Larsen RH, Bruland OS EUR J CANCER 2003 1 5 Abs 543
    • (2003) EUR J CANCER , vol.1 , Issue.5
    • Nilsson, S.1    Balteskard, L.2    Fossa, S.D.3    Westlin, J.-E.4    Borch, K.5    Larsen, R.H.6    Bruland, O.S.7
  • 42
    • 71249149005 scopus 로고    scopus 로고
    • Clinical development of bone-seeking 223Ra (Alpharadin): Current status
    • 1015816 June 14
    • 1015816 Clinical development of bone-seeking 223Ra (Alpharadin): Current status. Bruland O ABS SOC NUCLEAR MED ANN MEET 2009 June 14 Abs 35
    • (2009) ABS SOC NUCLEAR MED ANN MEET
    • Bruland, O.1
  • 46
    • 0345161422 scopus 로고    scopus 로고
    • The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogencontaining bisphosphonates
    • 1050612
    • 1050612 The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogencontaining bisphosphonates. van beek E, Lowik C, van der Pluijm G, Papapoulos S J BONE MINER RES 1999 14 5 722-729
    • (1999) J BONE MINER RES , vol.14 , Issue.5 , pp. 722-729
    • Van Beek, E.1    Lowik, C.2    Van Der Pluijm, G.3    Papapoulos, S.4
  • 47
    • 71249125372 scopus 로고    scopus 로고
    • A double-blind, randomised dose-response phase II, multicentre study of radium-223 for the palliation of painful bone metastases in castration refractory prostate cancer patients
    • 1051182
    • 1051182 A double-blind, randomised dose-response phase II, multicentre study of radium-223 for the palliation of painful bone metastases in castration refractory prostate cancer patients. Nilsson S, Strang P, Franzen L, Olivier P, Pecking A, Staffurth J, Vasanthan S, Andersson C, Bruland OS, Aksnes AK EJC SUPPL 2009 7 2 Abs P-7011
    • (2009) EJC SUPPL , vol.7 , Issue.2
    • Nilsson, S.1    Strang, P.2    Franzen, L.3    Olivier, P.4    Pecking, A.5    Staffurth, J.6    Vasanthan, S.7    Andersson, C.8    Bruland, O.S.9    Aksnes, A.K.10
  • 48
    • 71249139037 scopus 로고    scopus 로고
    • ?-Emitting radium-223: Two years follow up from a randomized phase II study in patients with bone metastases from hormone refractory prostate cancer
    • 1051184
    • 1051184 ?-Emitting radium-223: Two years follow up from a randomized phase II study in patients with bone metastases from hormone refractory prostate cancer. Nilsson S, Franzen L, Parker C, Bolstad B, Ramdahl T, Thuresson M, Bruland O EJC SUPPL 2009 7 2 Abs P-7018
    • (2009) EJC SUPPL , vol.7 , Issue.2
    • Nilsson, S.1    Franzen, L.2    Parker, C.3    Bolstad, B.4    Ramdahl, T.5    Thuresson, M.6    Bruland, O.7
  • 49
    • 71249134569 scopus 로고    scopus 로고
    • A double blind, randomised, dose finding, phase II, multicentre study of radium-223 for the treatment of patients with metastatic castration-refractory prostate cancer (CRPC): EudraCT number: 2005-003680-3722
    • 1051186
    • 1051186 A double blind, randomised, dose finding, phase II, multicentre study of radium-223 for the treatment of patients with metastatic castration-refractory prostate cancer (CRPC): EudraCT number: 2005-003680-3722 Parker C, Hoskin P, Pascoe S, Chodack A, O'Sullivan JM, Germa JR, Lokna A EJC SUPPL 2009 7 2 Abs O-7003
    • (2009) EJC SUPPL , vol.7 , Issue.2
    • Parker, C.1    Hoskin, P.2    Pascoe, S.3    Chodack, A.4    O'Sullivan, J.M.5    Germa, J.R.6    Lokna, A.7
  • 50
    • 0032434119 scopus 로고    scopus 로고
    • Palliative therapy with bone seeking radiopharmaceuticals
    • 1053621
    • 1053621 Palliative therapy with bone seeking radiopharmaceuticals. McEwan AJB CANCER BIOTHER RADIOPHARM 1998 13 6 413-426
    • (1998) CANCER BIOTHER RADIOPHARM , vol.13 , Issue.6 , pp. 413-426
    • McEwan, A.J.B.1
  • 51
    • 0037058653 scopus 로고    scopus 로고
    • The role of androgens and the androgen receptor in prostate cancer
    • 1053631
    • 1053631 The role of androgens and the androgen receptor in prostate cancer. Debes JD, Tindall DJ CANCER LETT 2002 187 1-2 1-7
    • (2002) CANCER LETT , vol.187 , Issue.1-2 , pp. 1-7
    • Debes, J.D.1    Tindall, D.J.2
  • 52
    • 0036755408 scopus 로고    scopus 로고
    • Chemotherapy for prostate cancer
    • 1053632
    • 1053632 Chemotherapy for prostate cancer. Gilligan T, Kantoff PW UROLOGY 2002 60 3A 94-100
    • (2002) UROLOGY , vol.60 , Issue.3 A , pp. 94-100
    • Gilligan, T.1    Kantoff, P.W.2
  • 53
    • 0026508582 scopus 로고
    • Metastatic bone disease: Clinical and therapeutic aspects
    • 1053634
    • 1053634 Metastatic bone disease: Clinical and therapeutic aspects. BODY JJ BONE 1992 13 S57-S62
    • (1992) BONE , vol.13
    • Body, J.J.1
  • 54
    • 0022476370 scopus 로고
    • Skeletal metastases
    • 1053635
    • 1053635 Skeletal metastases. Galasko CS CLIN ORTHOP 1986 210 18-30
    • (1986) CLIN ORTHOP , vol.210 , pp. 18-30
    • Galasko, C.S.1
  • 55
    • 0019981235 scopus 로고
    • Chemotherapy of metastatic cancer in bone
    • 1053636
    • 1053636 Chemotherapy of metastatic cancer in bone. Bhardwaj S, Holland JF CLIN ORTHOP 1982 169 28-37
    • (1982) CLIN ORTHOP , vol.169 , pp. 28-37
    • Bhardwaj, S.1    Holland, J.F.2
  • 57
    • 0025969367 scopus 로고
    • Bone metastases: Pathophysiology and management policy
    • 1053638
    • 1053638 Bone metastases: Pathophysiology and management policy. Nielsen OS, Munro AJ, Tannock IF J CLIN ONCOL 1991 9 3 509-524
    • (1991) J CLIN ONCOL , vol.9 , Issue.3 , pp. 509-524
    • Nielsen, O.S.1    Munro, A.J.2    Tannock, I.F.3
  • 58
    • 0033579957 scopus 로고    scopus 로고
    • Over-production of parathyroid hormone-related peptide results in increased osteolytic skeletal metastasis by prostate ancer cells in vivo
    • 1053640
    • 1053640 Over-production of parathyroid hormone-related peptide results in increased osteolytic skeletal metastasis by prostate ancer cells in vivo. Rabbani SA, Gladu J, Harakidas P, Jamison B, Goltzman D INT J CANCER 1999 80 2 257-264
    • (1999) INT J CANCER , vol.80 , Issue.2 , pp. 257-264
    • Rabbani, S.A.1    Gladu, J.2    Harakidas, P.3    Jamison, B.4    Goltzman, D.5
  • 59
    • 0027253667 scopus 로고
    • Bone destruction in cancer
    • 1053641
    • 1053641 Bone destruction in cancer. Ross Garrett I SEMIN ONCOL 1993 20 3 Suppl 2 4-9
    • (1993) SEMIN ONCOL , vol.20 , Issue.3 SUPPL. 2 , pp. 4-9
    • Ross Garrett, I.1
  • 60
    • 0032510163 scopus 로고    scopus 로고
    • Production of interleukin-11 in bone-derived endothelial cells and its role in the formation of osteolytic bone metastasis
    • 1053642
    • 1053642 Production of interleukin-11 in bone-derived endothelial cells and its role in the formation of osteolytic bone metastasis. Zhang Y, Fujita N, Oh-hara T, Morinaga Y, Nakagawa T, Yamada M, Tsuruo T ONCOGENE 1998 16 6 693-703
    • (1998) ONCOGENE , vol.16 , Issue.6 , pp. 693-703
    • Zhang, Y.1    Fujita, N.2    Oh-Hara, T.3    Morinaga, Y.4    Nakagawa, T.5    Yamada, M.6    Tsuruo, T.7
  • 61
    • 0023525654 scopus 로고
    • Bone metastases: Pathogenesis, treatment, and rationale for use of resorption inhibitors
    • 1053646
    • 1053646 Bone metastases: Pathogenesis, treatment, and rationale for use of resorption inhibitors. Scher HI, Yagoda A AM J MED 1987 82 2A 6-28
    • (1987) AM J MED , vol.82 , Issue.2 A , pp. 6-28
    • Scher, H.I.1    Yagoda, A.2
  • 63
    • 0021988069 scopus 로고
    • Adhesion, chemotaxis, and aggregation of walker carcinosarcoma cells in response to products of resorbing bone
    • 1053652
    • 1053652 Adhesion, chemotaxis, and aggregation of walker carcinosarcoma cells in response to products of resorbing bone. Magro C, Orr FW, Manishen WJ, Sivananthan K, Mokashi SS J NATL CANCER INST 1985 74 4 829-838
    • (1985) J NATL CANCER INST , vol.74 , Issue.4 , pp. 829-838
    • Magro, C.1    Orr, F.W.2    Manishen, W.J.3    Sivananthan, K.4    Mokashi, S.S.5
  • 64
    • 0019857559 scopus 로고
    • The cellular basis of metastatic bone-disease in patients with lung-cancer
    • 1053654
    • 1053654 The cellular basis of metastatic bone-disease in patients with lung-cancer. Cramer SF, Fried L, Carter KJ CANCER 1981 48-12 2649-2660
    • (1981) CANCER , vol.48 , Issue.12 , pp. 2649-2660
    • Cramer, S.F.1    Fried, L.2    Carter, K.J.3
  • 65
    • 0021061694 scopus 로고
    • Association of increased cyclic adenosine 3'-5'-monophosphate content in cultured human-breast cancer-cells and release of hydrolytic enzymes and bone-resorbing activity
    • 1053659
    • 1053659 Association of increased cyclic adenosine 3'-5'-monophosphate content in cultured human-breast cancer-cells and release of hydrolytic enzymes and bone-resorbing activity. Eilon G, Mundy GR CANCER RES 1983 43 12 5792-5794
    • (1983) CANCER RES , vol.43 , Issue.12 , pp. 5792-5794
    • Eilon, G.1    Mundy, G.R.2
  • 66
    • 0019350348 scopus 로고
    • Relation of osteoclast activating factor production to extent of bone-disease in multiple-myeloma
    • 1053664
    • 1053664 Relation of osteoclast activating factor production to extent of bone-disease in multiple-myeloma. Durie BG, Salmon SE, Mundy GR BR J HAEMATOL 1981 47 1 21-30
    • (1981) BR J HAEMATOL , vol.47 , Issue.1 , pp. 21-30
    • Durie, B.G.1    Salmon, S.E.2    Mundy, G.R.3
  • 67
  • 68
    • 0018395185 scopus 로고
    • Carcinoma of the breast associated with hyper-calcemia and the presence of parathyroid hormone-like substances in the tumor
    • 1053669
    • 1053669 Carcinoma of the breast associated with hyper-calcemia and the presence of parathyroid hormone-like substances in the tumor. Hirshorn JE, Vrhovsek E, Posen S J CLIN ENDOCRINOL METAB 1979 48 2 217-221
    • (1979) J CLIN ENDOCRINOL METAB , vol.48 , Issue.2 , pp. 217-221
    • Hirshorn, J.E.1    Vrhovsek, E.2    Posen, S.3
  • 69
    • 0021956021 scopus 로고
    • Effect of growth-factors on bone cell replication and differentiation
    • 1053671
    • 1053671 Effect of growth-factors on bone cell replication and differentiation. Canalis E CLIN ORTHOP 1985 193 246-263
    • (1985) CLIN ORTHOP , vol.193 , pp. 246-263
    • Canalis, E.1
  • 70
    • 0031021526 scopus 로고    scopus 로고
    • Correlation between bone metabolic markers and bone scan in prostatic cancer
    • 1053676
    • 1053676 Correlation between bone metabolic markers and bone scan in prostatic cancer. Maeda H, Koizumi M, Yoshimura K, Yamauchi T, Kawai T, Ogata E J UROL 1997 157 2 539-543
    • (1997) J UROL , vol.157 , Issue.2 , pp. 539-543
    • Maeda, H.1    Koizumi, M.2    Yoshimura, K.3    Yamauchi, T.4    Kawai, T.5    Ogata, E.6
  • 71
    • 0034659963 scopus 로고    scopus 로고
    • Biochemical markers and skeletal metastases
    • 1053677
    • 1053677 Biochemical markers and skeletal metastases. Demers LM, Costa L, Lipton A CANCER 2000 88 12 2919-2926
    • (2000) CANCER , vol.88 , Issue.12 , pp. 2919-2926
    • Demers, L.M.1    Costa, L.2    Lipton, A.3
  • 72
    • 0035010803 scopus 로고    scopus 로고
    • Metastatic bone disease: Clinical features, pathophysiology and treatment strategies
    • 1053679
    • 1053679 Metastatic bone disease: Clinical features, pathophysiology and treatment strategies. Coleman RE CANCER TREAT REV 2001 27 3 165-176
    • (2001) CANCER TREAT REV , vol.27 , Issue.3 , pp. 165-176
    • Coleman, R.E.1
  • 73
    • 0035425227 scopus 로고    scopus 로고
    • Biology of osteoclast activation in cancer
    • 1053682
    • 1053682 Biology of osteoclast activation in cancer. Roodman GD J CLIN ONCOL 2001 19 15 3562-3571
    • (2001) J CLIN ONCOL , vol.19 , Issue.15 , pp. 3562-3571
    • Roodman, G.D.1
  • 74
    • 0027127997 scopus 로고
    • Spinal cord compression from epidural metastases
    • 1053684
    • 1053684 Spinal cord compression from epidural metastases. Byrne TN N ENGL J MED 1992 327 9 614-619
    • (1992) N ENGL J MED , vol.327 , Issue.9 , pp. 614-619
    • Byrne, T.N.1
  • 75
    • 0032512905 scopus 로고    scopus 로고
    • Bone metastases - The clinical problem
    • 1053685
    • 1053685 Bone metastases - The clinical problem. Rubens RD EUR J CANCER 1998 34 2 210-213
    • (1998) EUR J CANCER , vol.34 , Issue.2 , pp. 210-213
    • Rubens, R.D.1
  • 76
    • 0025679358 scopus 로고
    • Cancer pain relief and palliative care
    • 1053686 Report of a WHO expert committee
    • 1053686 Cancer pain relief and palliative care. Report of a WHO expert committee. World Health Organization WHO TECH REP SER 1990 804 1-75
    • (1990) World Health Organization WHO TECH REP ser , vol.804 , pp. 1-75
  • 77
    • 0026576839 scopus 로고
    • Cancer pain: Pathophysiology and syndromes
    • 1053687
    • 1053687 Cancer pain: Pathophysiology and syndromes. Portenoy RK LANCET 1992 339 8800 1026-1031
    • (1992) LANCET , vol.339 , Issue.8800 , pp. 1026-1031
    • Portenoy, R.K.1
  • 78
    • 0028086057 scopus 로고
    • Management of cancer of the prostate
    • 1053692
    • 1053692 Management of cancer of the prostate. Catalona WJ N ENGL J MED 1994 331 15 996-1004
    • (1994) N ENGL J MED , vol.331 , Issue.15 , pp. 996-1004
    • Catalona, W.J.1
  • 81
    • 0141688330 scopus 로고    scopus 로고
    • Randomized, double-blind, controlled trial of mitoxantrone/prednisone and clodronate versus mitoxantrone/ prednisone and placebo in patients with hormone-refractory prostate cancer and pain
    • 1053707
    • 1053707 Randomized, double-blind, controlled trial of mitoxantrone/prednisone and clodronate versus mitoxantrone/ prednisone and placebo in patients with hormone-refractory prostate cancer and pain. Ernst DS, Tannock IF, Winquist EW, Venner PM, Reyno L, Moore MJ, Chi K, Ding K, Elliott C, Parulekar W J CLIN ONCOL 2003 21 17 3335-3342
    • (2003) J CLIN ONCOL , vol.21 , Issue.17 , pp. 3335-3342
    • Ernst, D.S.1    Tannock, I.F.2    Winquist, E.W.3    Venner, P.M.4    Reyno, L.5    Moore, M.J.6    Chi, K.7    Ding, K.8    Elliott, C.9    Parulekar, W.10
  • 82
    • 0030861185 scopus 로고    scopus 로고
    • Randomized comparison of total androgen blockade alone versus combined with weekly epirubicin in advanced prostate cancer
    • 1053720
    • 1053720 Randomized comparison of total androgen blockade alone versus combined with weekly epirubicin in advanced prostate cancer. Pummer K, Lehnert M, Stettner H, Hubmer G EUR UROL 1997 32 Suppl 3 81-85
    • (1997) EUR UROL , vol.32 , Issue.SUPPL. 3 , pp. 81-85
    • Pummer, K.1    Lehnert, M.2    Stettner, H.3    Hubmer, G.4
  • 83
    • 33846515135 scopus 로고    scopus 로고
    • Weekly docetaxel and epirubicin in treatment of advanced hormone-refractory prostate cancer
    • 1053727
    • 1053727 Weekly docetaxel and epirubicin in treatment of advanced hormone-refractory prostate cancer. Petrioll R, Paolelli L, Francini E, Manganelli A, Salvestrini F, Francini G UROLOGY 2007 69 1 142-146
    • (2007) UROLOGY , vol.69 , Issue.1 , pp. 142-146
    • Petrioll, R.1    Paolelli, L.2    Francini, E.3    Manganelli, A.4    Salvestrini, F.5    Francini, G.6
  • 84
    • 56249147452 scopus 로고    scopus 로고
    • The role of doxorubicin and epirubicin in the treatment of patients with metastatic hormone-refractory prostate cancer
    • 1053728
    • 1053728 The role of doxorubicin and epirubicin in the treatment of patients with metastatic hormone-refractory prostate cancer. Petrioli R, Fiaschi AI, Francini E, Pascucci A, Francini G CANCER TREAT REV 2008 34 8 710-718
    • (2008) CANCER TREAT REV , vol.34 , Issue.8 , pp. 710-718
    • Petrioli, R.1    Fiaschi, A.I.2    Francini, E.3    Pascucci, A.4    Francini, G.5
  • 87
    • 0033956932 scopus 로고    scopus 로고
    • Paclitaxel versus doxorubicin as first-line singleagent chemotherapy for metastatic breast cancer: A European Organization for Research and Treatment of Cancer randomized study with cross-over
    • 1053761
    • 1053761 Paclitaxel versus doxorubicin as first-line singleagent chemotherapy for metastatic breast cancer: A European Organization for Research and Treatment of Cancer randomized study with cross-over. Paridaens R, Biganzoli L, Bruning P, Klijn JGM, Gamucci T, Houston S, Coleman R, Schachter J, Van Vreckem A, Sylvester R, Awada A et al J CLIN ONCOL 2000 18 4 724-733
    • (2000) J CLIN ONCOL , vol.18 , Issue.4 , pp. 724-733
    • Paridaens, R.1    Biganzoli, L.2    Bruning, P.3    Klijn, J.G.M.4    Gamucci, T.5    Houston, S.6    Coleman, R.7    Schachter, J.8    Van Vreckem, A.9    Sylvester, R.10    Awada, A.11
  • 88
    • 0037441856 scopus 로고    scopus 로고
    • Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: An intergroup trial (E1193)
    • 1053774
    • 1053774 Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: An intergroup trial (E1193). Sledge GW, Neuberg D, Bernardo P, Ingle JN, Martino S, Rowinsky EK, Wood WC J CLIN ONCOL 2003 21 4 588-592
    • (2003) J CLIN ONCOL , vol.21 , Issue.4 , pp. 588-592
    • Sledge, G.W.1    Neuberg, D.2    Bernardo, P.3    Ingle, J.N.4    Martino, S.5    Rowinsky, E.K.6    Wood, W.C.7
  • 89
    • 0030860617 scopus 로고    scopus 로고
    • Docetaxel as single-agent therapy in metastatic breast cancer: Clinical efficacy
    • 1053787
    • 1053787 Docetaxel as single-agent therapy in metastatic breast cancer: Clinical efficacy. Valero V SEMIN ONCOL 1997 24 4 S11-S18
    • (1997) SEMIN ONCOL , vol.24 , Issue.4
    • Valero, V.1
  • 91
    • 0036302586 scopus 로고    scopus 로고
    • Phase II study of weekly docetaxel in patients with metastatic breast cancer
    • 1053979
    • 1053979 Phase II study of weekly docetaxel in patients with metastatic breast cancer. Aihara T, Kim Y, Takatsuka Y ANN ONCOL 2002 13 2 286-292
    • (2002) ANN ONCOL , vol.13 , Issue.2 , pp. 286-292
    • Aihara, T.1    Kim, Y.2    Takatsuka, Y.3
  • 92
    • 0030838804 scopus 로고    scopus 로고
    • Bisphosphonates and breast carcinoma
    • 1053983
    • 1053983 Bisphosphonates and breast carcinoma. Lipton A CANCER 1997 80 8 1668-1673
    • (1997) CANCER , vol.80 , Issue.8 , pp. 1668-1673
    • Lipton, A.1
  • 93
    • 0030931858 scopus 로고    scopus 로고
    • Bisphosphonates induce apoptosis in human myeloma cell lines: A novel anti-tumour activity
    • 1053987
    • 1053987 Bisphosphonates induce apoptosis in human myeloma cell lines: A novel anti-tumour activity. Shipman CM, Rogers MJ, Apperley JF, Graham R, Russell G, Croucher PI BR J HAEMATOL 1997 98 3 665-672
    • (1997) BR J HAEMATOL , vol.98 , Issue.3 , pp. 665-672
    • Shipman, C.M.1    Rogers, M.J.2    Apperley, J.F.3    Graham, R.4    Russell, G.5    Croucher, P.I.6
  • 94
    • 0035917560 scopus 로고    scopus 로고
    • The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: Evidence for synergy with paclitaxel
    • 1054005
    • 1054005 The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: Evidence for synergy with paclitaxel. Jagdev SP, Coleman RE, Shipman CM, Rostami-H A, Croucher PI BR J CANCER 2001 84 8 1126-1134
    • (2001) BR J CANCER , vol.84 , Issue.8 , pp. 1126-1134
    • Jagdev, S.P.1    Coleman, R.E.2    Shipman, C.M.3    Rostami-H, A.4    Croucher, P.I.5
  • 95
    • 0030176390 scopus 로고    scopus 로고
    • Effects of oral clodronate on bone mineral density in patients with relapsing breast cancer
    • 1054007
    • 1054007 Effects of oral clodronate on bone mineral density in patients with relapsing breast cancer. Rizzoli R, Forni M, Schaad MA, Slosman DO, Sappino AP, Garcia J, Bonjour JP BONE 1996 18 6 531-537
    • (1996) BONE , vol.18 , Issue.6 , pp. 531-537
    • Rizzoli, R.1    Forni, M.2    Schaad, M.A.3    Slosman, D.O.4    Sappino, A.P.5    Garcia, J.6    Bonjour, J.P.7
  • 98
    • 0036138734 scopus 로고    scopus 로고
    • Bisphosphonates suppress bone resorption by a direct effect on early osteoclast precursors without affecting the osteoclastogenic capacity of osteogenic cells: The role of protein geranylgeranylation in the action of nitrogen-containing bisphosphonates on osteoclast precursors
    • 1054021
    • 1054021 Bisphosphonates suppress bone resorption by a direct effect on early osteoclast precursors without affecting the osteoclastogenic capacity of osteogenic cells: The role of protein geranylgeranylation in the action of nitrogen-containing bisphosphonates on osteoclast precursors. Van Beek ER, Lowik CWGM, Papapoulos SE BONE 2002 30 1 64-70
    • (2002) BONE , vol.30 , Issue.1 , pp. 64-70
    • Van Beek, E.R.1    Cwgm, L.2    Papapoulos, S.E.3
  • 101
    • 0035148170 scopus 로고    scopus 로고
    • Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5-year results of a randomized controlled trial
    • 1054026
    • 1054026 Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5-year results of a randomized controlled trial. Saarto T, Blomqvist C, Virkkunen P, Elomaa I J CLIN ONCOL 2001 19 1 10-17
    • (2001) J CLIN ONCOL , vol.19 , Issue.1 , pp. 10-17
    • Saarto, T.1    Blomqvist, C.2    Virkkunen, P.3    Elomaa, I.4
  • 102
    • 0036393344 scopus 로고    scopus 로고
    • Ibandronate in the treatment of prostate cancer associated painful osseous metastases
    • 1054049
    • 1054049 Ibandronate in the treatment of prostate cancer associated painful osseous metastases. Heidenreich A, Elert A, Hofmann R PROSTATE CANCER PROSTATIC DIS 2002 5 3 231-235
    • (2002) PROSTATE CANCER PROSTATIC DIS , vol.5 , Issue.3 , pp. 231-235
    • Heidenreich, A.1    Elert, A.2    Hofmann, R.3
  • 103
    • 33646869430 scopus 로고    scopus 로고
    • Effect of zoledronic acid on pain associated with bone metastasis in patients with prostate cancer
    • DOI 10.1093/annonc/mdl041
    • 1054051 Effect of zoledronic acid on pain associated with bone metastasis in patients with prostate cancer. Weinfurt KP, Anstrom KJ, Castel LD, Schulman KA, Saad F ANN ONCOL 2006 17 6 986-989 (Pubitemid 43778991)
    • (2006) Annals of Oncology , vol.17 , Issue.6 , pp. 986-989
    • Weinfurt, K.P.1    Anstrom, K.J.2    Castel, L.D.3    Schulman, K.A.4    Saad, F.5
  • 104
    • 0018252833 scopus 로고
    • The role of radiotherapy in management of metastatic bone disease
    • 1054109
    • 1054109 The role of radiotherapy in management of metastatic bone disease. Kumar PP, Bahrassa F, Espinoza MC J NATL MED ASSOC 1978 70 12 909-911
    • (1978) J NATL MED ASSOC , vol.70 , Issue.12 , pp. 909-911
    • Kumar, P.P.1    Bahrassa, F.2    Espinoza, M.C.3
  • 105
    • 0017836127 scopus 로고
    • Effectiveness of radiation-therapy in treatment of bone metastases from breast-cancer
    • 1054110
    • 1054110 Effectiveness of radiation-therapy in treatment of bone metastases from breast-cancer. Garmatis CJ, Chu FC RADIOLOGY 1978 126 1 235-237
    • (1978) RADIOLOGY , vol.126 , Issue.1 , pp. 235-237
    • Garmatis, C.J.1    Chu, F.C.2
  • 106
    • 0019983721 scopus 로고
    • Radiation-therapy for bone metastasis
    • 1054112
    • 1054112 Radiation-therapy for bone metastasis. Schocker JD, Brady LW CLIN ORTHOP 1982 169 38-43
    • (1982) CLIN ORTHOP , vol.169 , pp. 38-43
    • Schocker, J.D.1    Brady, L.W.2
  • 107
    • 0019972743 scopus 로고
    • The palliation of symptomatic osseous metastases: Final results of the study by the Radiation Therapy Oncology Group
    • 1054117
    • 1054117 The palliation of symptomatic osseous metastases: Final results of the study by the Radiation Therapy Oncology Group. Tong D, Gillick L, Hendrickson FR CANCER 1982 50 5 893-899
    • (1982) CANCER , vol.50 , Issue.5 , pp. 893-899
    • Tong, D.1    Gillick, L.2    Hendrickson, F.R.3
  • 110
    • 0036380479 scopus 로고    scopus 로고
    • Palliative radiotherapy in the treatment of skeletal metastases
    • 1054141
    • 1054141 Palliative radiotherapy in the treatment of skeletal metastases. Saarto T, Janes R, Tenhunen M, Kouri M EUR J PAIN 2002 6 5 323-330
    • (2002) EUR J PAIN , vol.6 , Issue.5 , pp. 323-330
    • Saarto, T.1    Janes, R.2    Tenhunen, M.3    Kouri, M.4
  • 111
    • 0031281360 scopus 로고    scopus 로고
    • Pain relief and quality of life following radiotherapy for bone metastases: A randomised trial of two fractionation schedules
    • 1054148
    • 1054148 Pain relief and quality of life following radiotherapy for bone metastases: A randomised trial of two fractionation schedules. Gaze MN, Kelly CG, Kerr GR, Cull A, Cowie VJ, Gregor A, Howard GCW, Rodger A RADIOTHER ONCOL 1997 45 2 109-116
    • (1997) RADIOTHER ONCOL , vol.45 , Issue.2 , pp. 109-116
    • Gaze, M.N.1    Kelly, C.G.2    Kerr, G.R.3    Cull, A.4    Cowie, V.J.5    Gregor, A.6    Howard, G.C.W.7    Rodger, A.8
  • 112
    • 0031745945 scopus 로고    scopus 로고
    • Randomized trial of single dose versus fractionated palliative radiotherapy of bone metastases
    • 1054149
    • 1054149 Randomized trial of single dose versus fractionated palliative radiotherapy of bone metastases. Nielsen OS, Bentzen SM, Sandberg E, Gadeberg CC, Timothy AR RADIOTHER ONCOL 1998 47 3 233-240
    • (1998) RADIOTHER ONCOL , vol.47 , Issue.3 , pp. 233-240
    • Nielsen, O.S.1    Bentzen, S.M.2    Sandberg, E.3    Gadeberg, C.C.4    Timothy, A.R.5
  • 113
    • 0029133334 scopus 로고
    • Single-dose radiotherapy (6 Gy): Palliation in painful bone metastases
    • 1054150
    • 1054150 Single-dose radiotherapy (6 Gy): Palliation in painful bone metastases. Uppelschoten JM, Wanders SL, de Jong JM RADIOTHER ONCOL 1995 36 3 198-202
    • (1995) RADIOTHER ONCOL , vol.36 , Issue.3 , pp. 198-202
    • Uppelschoten, J.M.1    Wanders, S.L.2    De Jong, J.M.3
  • 114
    • 0021986652 scopus 로고
    • Reanalysis of the RTOG study of the palliation of symptomatic osseous metastasis
    • 1054151
    • 1054151 Reanalysis of the RTOG study of the palliation of symptomatic osseous metastasis. Blitzer PH CANCER 1985 55 7 1468-1472
    • (1985) CANCER , vol.55 , Issue.7 , pp. 1468-1472
    • Blitzer, P.H.1
  • 115
    • 0032410013 scopus 로고    scopus 로고
    • Radiation therapy in the management of symptomatic bone metastases: The effect of total dose and histology on pain relief and response duration
    • 1054157
    • 1054157 Radiation therapy in the management of symptomatic bone metastases: The effect of total dose and histology on pain relief and response duration. Arcangeli G, Giovinazzo G, Saracino B, D'Angelo L, Giannarelli D, Arcangeli G, Micheli A INT J RADIAT ONCOL BIOL PHYS 1998 42 5 1119-1126
    • (1998) INT J RADIAT ONCOL BIOL PHYS , vol.42 , Issue.5 , pp. 1119-1126
    • Arcangeli, G.1    Giovinazzo, G.2    Saracino, B.3    D'Angelo, L.4    Giannarelli, D.5    Arcangeli, G.6    Micheli, A.7
  • 116
    • 0032970560 scopus 로고    scopus 로고
    • Bone metastasis: Review and critical analysis of random allocation trials of local field treatment
    • 1054160
    • 1054160 Bone metastasis: Review and critical analysis of random allocation trials of local field treatment. Ratanatharathorn V, Powers WE, Moss WT, Perez CA INT J RADIAT ONCOL BIOL PHYS 1999 44 1 1-18
    • (1999) INT J RADIAT ONCOL BIOL PHYS , vol.44 , Issue.1 , pp. 1-18
    • Ratanatharathorn, V.1    Powers, W.E.2    Moss, W.T.3    Perez, C.A.4
  • 117
    • 0024514412 scopus 로고
    • Half-body irradiation for treatment of widely metastatic adenocarcinoma of the prostate
    • 1054162
    • 1054162 Half-body irradiation for treatment of widely metastatic adenocarcinoma of the prostate. Kuban DA, Delbridge T, el-Mahdi AM, Schellhammer PF J UROL 1989 141 3 572-574
    • (1989) J UROL , vol.141 , Issue.3 , pp. 572-574
    • Kuban, D.A.1    Delbridge, T.2    El-Mahdi, A.M.3    Schellhammer, P.F.4
  • 118
    • 0022618134 scopus 로고
    • Single-dose half-body irradiation for palliation of multiple bone metastases from solid tumors
    • 1054164 Final Radiation Therapy Oncology Group report.
    • 1054164 Single-dose half-body irradiation for palliation of multiple bone metastases from solid tumors. Final Radiation Therapy Oncology Group report. Salazar OM, Rubin P, Hendrickson FR, Komaki R, Poulter C, Newall J, Asbell SO, Mohiuddin M, Vaness J CANCER 1986 58 1 29-36
    • (1986) CANCER , vol.58 , Issue.1 , pp. 29-36
    • Salazar, O.M.1    Rubin, P.2    Hendrickson, F.R.3    Komaki, R.4    Poulter, C.5    Newall, J.6    Asbell, S.O.7    Mohiuddin, M.8    Vaness, J.9
  • 120
    • 0023014511 scopus 로고
    • Impending pathologic fractures from metastatic malignancy: Evaluation and management
    • 1054174
    • 1054174 Impending pathologic fractures from metastatic malignancy: Evaluation and management. Harrington KD INSTR COURSE LECT 1986 35 357-381
    • (1986) INSTR COURSE LECT , vol.35 , pp. 357-381
    • Harrington, K.D.1
  • 121
    • 0026825722 scopus 로고
    • Metastatic bone disease: Current concepts of clinicopathophysiology and modern surgical treatment
    • 1054180
    • 1054180 Metastatic bone disease: Current concepts of clinicopathophysiology and modern surgical treatment. Sim FH, Frassica FJ, Frassica DA ANN ACAD MED SINGAPORE 1992 21 2 274-279
    • (1992) ANN ACAD MED SINGAPORE , vol.21 , Issue.2 , pp. 274-279
    • Sim, F.H.1    Frassica, F.J.2    Frassica, D.A.3
  • 122
    • 0020613175 scopus 로고
    • Fracture-healing in metastatic bone-disease
    • 1054181
    • 1054181 Fracture-healing in metastatic bone-disease. Gainor BJ, Buchert P CLIN ORTHOP 1983 178 297-302
    • (1983) CLIN ORTHOP , vol.178 , pp. 297-302
    • Gainor, B.J.1    Buchert, P.2
  • 124
    • 0034036898 scopus 로고    scopus 로고
    • Cavity theory applied to the dosimetry of systemic radiotherapy of bone metastases
    • 1054183
    • 1054183 Cavity theory applied to the dosimetry of systemic radiotherapy of bone metastases. Breen SL, Battista JJ PHYS MED BIOL 2000 45 4 879-896
    • (2000) PHYS MED BIOL , vol.45 , Issue.4 , pp. 879-896
    • Breen, S.L.1    Battista, J.J.2
  • 125
    • 84873753506 scopus 로고
    • The use of radioactive phosphorus in the treatment of carcinoma of the breast with widespread metastases to bone
    • 1054186
    • 1054186 The use of radioactive phosphorus in the treatment of carcinoma of the breast with widespread metastases to bone. Friedell HL, Storaasli JP AM J ROENTGENOL 1950 64 4 559-575
    • (1950) AM J ROENTGENOL , vol.64 , Issue.4 , pp. 559-575
    • Friedell, H.L.1    Storaasli, J.P.2
  • 126
    • 0027270333 scopus 로고
    • The treatment of painful osseous metastases with phosphorus-32-labeled phosphates
    • 1054189
    • 1054189 The treatment of painful osseous metastases with phosphorus-32-labeled phosphates. Silberstein EB SEMIN ONCOL 1993 20 3 10-21
    • (1993) SEMIN ONCOL , vol.20 , Issue.3 , pp. 10-21
    • Silberstein, E.B.1
  • 127
    • 0032588599 scopus 로고    scopus 로고
    • Relative efficacy of 32P and 89Sr in palliation in skeletal metastases
    • 1054191
    • 1054191 Relative efficacy of 32P and 89Sr in palliation in skeletal metastases. Nair N J NUCL MED 1999 40 2 256-261
    • (1999) J NUCL MED , vol.40 , Issue.2 , pp. 256-261
    • Nair, N.1
  • 128
    • 0018181321 scopus 로고
    • Palliative radiotherapy with strontium-89 in case of extended formation of skeleton metastases
    • 1054198
    • 1054198 Palliative radiotherapy with strontium-89 in case of extended formation of skeleton metastases. Kutzner J, Grimm W, Hahn K STRAHLENTHERAPIE 1978 154 5 317-322
    • (1978) STRAHLENTHERAPIE , vol.154 , Issue.5 , pp. 317-322
    • Kutzner, J.1    Grimm, W.2    Hahn, K.3
  • 129
    • 0022374032 scopus 로고
    • Strontium-89 therapy for the pain of osseous metastases
    • 1054202
    • 1054202 Strontium-89 therapy for the pain of osseous metastases. Silberstein EB, Williams C J NUCL MED 1985 26 4 345-348
    • (1985) J NUCL MED , vol.26 , Issue.4 , pp. 345-348
    • Silberstein, E.B.1    Williams, C.2
  • 131
    • 0023117505 scopus 로고
    • Strontium-89 therapy: Strontium kinetics and dosimetry in two patients treated for metastasising osteosarcoma
    • 1054206
    • 1054206 Strontium-89 therapy: Strontium kinetics and dosimetry in two patients treated for metastasising osteosarcoma. Blake GM, Zivanovic MA, McEwan AJ, Condon BR, Ackery DM BR J RADIOL 1987 60 711 253-259
    • (1987) BR J RADIOL , vol.60 , Issue.711 , pp. 253-259
    • Blake, G.M.1    Zivanovic, M.A.2    McEwan, A.J.3    Condon, B.R.4    Ackery, D.M.5
  • 132
    • 0025781809 scopus 로고
    • A prospective, randomised double-blind crossover study to examine the efficacy of strontium-89 in pain palliation in patients with advanced prostate cancer metastatic to bone
    • 1054213
    • 1054213 A prospective, randomised double-blind crossover study to examine the efficacy of strontium-89 in pain palliation in patients with advanced prostate cancer metastatic to bone. Lewington VJ, McEwan AJ, Ackery DM, Bayly RJ, Keeling DH, Macleod PM, Porter AT, Zivanovic MA EUR J CANCER 1991 27 8 954-958
    • (1991) EUR J CANCER , vol.27 , Issue.8 , pp. 954-958
    • Lewington, V.J.1    McEwan, A.J.2    Ackery, D.M.3    Bayly, R.J.4    Keeling, D.H.5    MacLeod, P.M.6    Porter, A.T.7    Zivanovic, M.A.8
  • 133
    • 0028377317 scopus 로고
    • Systemic radionuclide therapy of bone metastases with strontium-89
    • 1054215
    • 1054215 Systemic radionuclide therapy of bone metastases with strontium-89. Porter AT, Davis LP ONCOLOGY-NY 1994 8 2 93-96
    • (1994) ONCOLOGY-NY , vol.8 , Issue.2 , pp. 93-96
    • Porter, A.T.1    Davis, L.P.2
  • 134
    • 0029154728 scopus 로고
    • Strontium-89 therapy for the palliation of pain due to osseous metastases
    • 1054216
    • 1054216 Strontium-89 therapy for the palliation of pain due to osseous metastases. Robinson RG, Preston DF, Schiefelbein M, Baxter KG JAMA-J AM MED ASSOC 1995 274 5 420-424
    • (1995) JAMA-J AM MED ASSOC , vol.274 , Issue.5 , pp. 420-424
    • Robinson, R.G.1    Preston, D.F.2    Schiefelbein, M.3    Baxter, K.G.4
  • 137
  • 138
    • 0043236317 scopus 로고    scopus 로고
    • Therapeutic efficiency of rhenium-188-HEDP in human prostate cancer skeletal metastases
    • DOI 10.1038/sj.bjc.6601158
    • 1054222 Therapeutic efficiency of rhenium-188-HEDP in human prostate cancer skeletal metastases. Liepe K, Kropp J, Runge R, Kotzerke J BR J CANCER 2003 89 4 625-629 (Pubitemid 37076163)
    • (2003) British Journal of Cancer , vol.89 , Issue.4 , pp. 625-629
    • Liepe, K.1    Kropp, J.2    Runge, R.3    Kotzerke, J.4
  • 139
    • 0033626273 scopus 로고    scopus 로고
    • 99mTc (V)DMSA quantitatively predicts 188Re(V)DMSA distribution in patients with prostate cancer metastatic to bone
    • 1054230
    • 1054230 99mTc(V)DMSA quantitatively predicts 188Re(V)DMSA distribution in patients with prostate cancer metastatic to bone. Blower PJ, Kettle AG, O'Doherty MJ, Coakley AJ, Knapp FF EUR J NUCL MED 2000 27 9 1405-1409
    • (2000) EUR J NUCL MED , vol.27 , Issue.9 , pp. 1405-1409
    • Blower, P.J.1    Kettle, A.G.2    O'Doherty, M.J.3    Coakley, A.J.4    Knapp, F.F.5
  • 140
    • 0024803298 scopus 로고
    • A phase i study of samarium-153 ethylenediaminetetramethylene phosphonate therapy for disseminated skeletal metastases
    • 1054231
    • 1054231 A phase I study of samarium-153 ethylenediaminetetramethylene phosphonate therapy for disseminated skeletal metastases. Turner JH, Claringbold PG, Hetherington EL, Sorby P, Martindale AA J CLIN ONCOL 1989 7 12 1926-1931
    • (1989) J CLIN ONCOL , vol.7 , Issue.12 , pp. 1926-1931
    • Turner, J.H.1    Claringbold, P.G.2    Hetherington, E.L.3    Sorby, P.4    Martindale, A.A.5
  • 141
    • 0026750068 scopus 로고
    • Samarium-153-EDTMP: Pharmacokinetic, toxicity and pain response using an escalating dose schedule in treatment of metastatic bone cancer
    • 1054234
    • 1054234 Samarium-153-EDTMP: Pharmacokinetic, toxicity and pain response using an escalating dose schedule in treatment of metastatic bone cancer. Farhanghi M, Holmes RA, Volkert WA, Logan KW, Singh A J NUCL MED 1992 33 8 1451-1458
    • (1992) J NUCL MED , vol.33 , Issue.8 , pp. 1451-1458
    • Farhanghi, M.1    Holmes, R.A.2    Volkert, W.A.3    Logan, K.W.4    Singh, A.5
  • 142
    • 0026862881 scopus 로고
    • Samarium-153-labelled EDTMP for bone metastases from cancer of the prostate
    • 1054235
    • 1054235 Samarium-153-labelled EDTMP for bone metastases from cancer of the prostate. Sandeman TF, Budd RS, Martin JJ CLIN ONCOL-UK 1992 4 3 160-164
    • (1992) CLIN ONCOL-UK , vol.4 , Issue.3 , pp. 160-164
    • Sandeman, T.F.1    Budd, R.S.2    Martin, J.J.3
  • 144
    • 0033061339 scopus 로고    scopus 로고
    • Multicentre trial on the efficacy and toxicity of single-dose samarium-153-ethylene diamine tetramethylene phosphonate as a palliative treatment for painful skeletal metastases in China
    • 1054242
    • 1054242 Multicentre trial on the efficacy and toxicity of single-dose samarium-153-ethylene diamine tetramethylene phosphonate as a palliative treatment for painful skeletal metastases in China. Tian JH, Zhang JM, Hou QT, Oyang QH, Wang JM, Luan ZS, Chuan L, He YJ EUR J NUCL MED 1999 26 1 2-7
    • (1999) EUR J NUCL MED , vol.26 , Issue.1 , pp. 2-7
    • Tian, J.H.1    Zhang, J.M.2    Hou, Q.T.3    Oyang, Q.H.4    Wang, J.M.5    Luan, Z.S.6    Chuan, L.7    He, Y.J.8
  • 145
    • 0034659856 scopus 로고    scopus 로고
    • Samarium Sm-153 lexidronam for the palliation of bone pain associated with metastases
    • 1054243
    • 1054243 Samarium Sm-153 lexidronam for the palliation of bone pain associated with metastases. Serafini AN CANCER 2000 88 12 2934-2939
    • (2000) CANCER , vol.88 , Issue.12 , pp. 2934-2939
    • Serafini, A.N.1
  • 146
    • 0036319351 scopus 로고    scopus 로고
    • Samarium-153-EDTMP bone uptake rate and its relation to therapeutic effect
    • 1054246
    • 1054246 Samarium-153-EDTMP bone uptake rate and its relation to therapeutic effect. Li L, Liang ZL, Deng HF, Kuang AR, Tan TZ, Luo SZ CHIN MED J (ENGL) 2002 115 7 1096-1098
    • (2002) CHIN MED J (ENGL) , vol.115 , Issue.7 , pp. 1096-1098
    • Li, L.1    Liang, Z.L.2    Deng, H.F.3    Kuang, A.R.4    Tan, T.Z.5    Luo, S.Z.6
  • 147
    • 0027166189 scopus 로고
    • Absorbed dose calculations in Haversian canals for several ?-emitting radionuclides
    • 1054247
    • 1054247 Absorbed dose calculations in Haversian canals for several ?-emitting radionuclides. Akabani G J NUCL MED 1993 34 8 1361-1366
    • (1993) J NUCL MED , vol.34 , Issue.8 , pp. 1361-1366
    • Akabani, G.1
  • 149
    • 0018184798 scopus 로고
    • Mean skeletal dose factors for ?-particle emitters in human bone. Part I: Volume-seeking radionuclides
    • 1054256
    • 1054256 Mean skeletal dose factors for ?-particle emitters in human bone. Part I: Volume-seeking radionuclides. Spiers FW, Beddoe AH, Whitwell JR BR J RADIOL 1978 51 608 622-627
    • (1978) BR J RADIOL , vol.51 , Issue.608 , pp. 622-627
    • Spiers, F.W.1    Beddoe, A.H.2    Whitwell, J.R.3
  • 150
    • 0026482280 scopus 로고
    • Radiopharmaceuticals for palliation of metastatic osseous lesions: Biologic and physical background
    • 1054260
    • 1054260 Radiopharmaceuticals for palliation of metastatic osseous lesions: Biologic and physical background. Hosain F, Spencer RP SEMIN NUCL MED 1992 22 1 11-16
    • (1992) SEMIN NUCL MED , vol.22 , Issue.1 , pp. 11-16
    • Hosain, F.1    Spencer, R.P.2
  • 151
    • 0026725284 scopus 로고
    • Dose estimation in strontium-89 radiotherapy of metastatic prostatic carcinoma
    • 1054261
    • 1054261 Dose estimation in strontium-89 radiotherapy of metastatic prostatic carcinoma. Breen SL, Powe JE, Porter AT J NUCL MED 1992 33 7 1316-1323
    • (1992) J NUCL MED , vol.33 , Issue.7 , pp. 1316-1323
    • Breen, S.L.1    Powe, J.E.2    Porter, A.T.3
  • 152
    • 0020077001 scopus 로고
    • Phosphate homeostasis and hypophosphatemia
    • 1054265
    • 1054265 Phosphate homeostasis and hypophosphatemia. Stoff JS AM J MED 1982 72 3 489-495
    • (1982) AM J MED , vol.72 , Issue.3 , pp. 489-495
    • Stoff, J.S.1
  • 154
    • 0032054461 scopus 로고    scopus 로고
    • Overview of nuclides for bone pain palliation
    • 1054269
    • 1054269 Overview of nuclides for bone pain palliation. Atkins HL APPL RADIAT ISOT 1998 49 4 277-283
    • (1998) APPL RADIAT ISOT , vol.49 , Issue.4 , pp. 277-283
    • Atkins, H.L.1
  • 155
    • 0024803298 scopus 로고
    • A phase i study of samarium-153 ethylenediaminetetramethylene phosphonate therapy for disseminated skeletal metastases
    • 1054271
    • 1054271 A phase I study of samarium-153 ethylenediaminetetramethylene phosphonate therapy for disseminated skeletal metastases. Turner JH, Claringbold PG, Hetherington EF, Sorby PF, Martindale AA J CLIN ONCOL 1989 7 12 1926-1931
    • (1989) J CLIN ONCOL , vol.7 , Issue.12 , pp. 1926-1931
    • Turner, J.H.1    Claringbold, P.G.2    Hetherington, E.F.3    Sorby, P.F.4    Martindale, A.A.5
  • 159
    • 0042887586 scopus 로고    scopus 로고
    • Repeated bone-targeted therapy for hormonerefractory prostate carcinoma: Randomized phase II trial with the new, high-energy radiopharmaceutical rhenium-188 hydroxyethylidenediphosphonate
    • 1054277
    • 1054277 Repeated bone-targeted therapy for hormonerefractory prostate carcinoma: Randomized phase II trial with the new, high-energy radiopharmaceutical rhenium-188 hydroxyethylidenediphosphonate. Palmedo H, Manka-Waluch A, Albers P, Schmidt-Wolf IGH, Reinhardt M, Ezziddin S, Joe A, Roedel R, Fimmers R, Knapp FF, Guhlke S et al J CLIN ONCOL 2003 21 15 2869-2875
    • (2003) J CLIN ONCOL , vol.21 , Issue.15 , pp. 2869-2875
    • Palmedo, H.1    Manka-Waluch, A.2    Albers, P.3    Schmidt-Wolf, I.G.H.4    Reinhardt, M.5    Ezziddin, S.6    Joe, A.7    Roedel, R.8    Fimmers, R.9    Knapp, F.F.10    Guhlke, S.11
  • 161
    • 0017888775 scopus 로고
    • Use of radium-224 in the treatment of ankylosing spondylitis and rheumatoid synovitis
    • 1054280
    • 1054280 Use of radium-224 in the treatment of ankylosing spondylitis and rheumatoid synovitis. Bertrand A, Legras B, Martin J HEALTH PHYS 1978 35 1 57-60
    • (1978) HEALTH PHYS , vol.35 , Issue.1 , pp. 57-60
    • Bertrand, A.1    Legras, B.2    Martin, J.3
  • 162
    • 44849138772 scopus 로고    scopus 로고
    • Increased risk of myeloid leukaemia in patients with ankylosing spondylitis following treatment with radium-224
    • 1054282
    • 1054282 Increased risk of myeloid leukaemia in patients with ankylosing spondylitis following treatment with radium-224. Wick RR, Nekolla EA, Gaubitz M, Schulte TL RHEUMATOLOGY 2008 47 6 855-859
    • (2008) RHEUMATOLOGY , vol.47 , Issue.6 , pp. 855-859
    • Wick, R.R.1    Nekolla, E.A.2    Gaubitz, M.3    Schulte, T.L.4
  • 164
    • 0036152138 scopus 로고    scopus 로고
    • Effects of low-dose cisplatin on 89Sr therapy for painful bone metastases from prostate cancer: A randomized clinical trial
    • 1054284
    • 1054284 Effects of low-dose cisplatin on 89Sr therapy for painful bone metastases from prostate cancer: A randomized clinical trial. Sciuto R, Festa A, Rea S, Pasqualoni R, Bergomi S, Petrilli G, Maini CL J NUCL MED 2002 43 1 79-86
    • (2002) J NUCL MED , vol.43 , Issue.1 , pp. 79-86
    • Sciuto, R.1    Festa, A.2    Rea, S.3    Pasqualoni, R.4    Bergomi, S.5    Petrilli, G.6    Maini, C.L.7
  • 166
    • 0036204649 scopus 로고    scopus 로고
    • Strontium-89 (Metastron) and the bisphosphonate olpadronate reduce the incidence of spinal cord compression in patients with hormone-refractory prostate cancer metastatic to the skeleton
    • 1054289
    • 1054289 Strontium-89 (Metastron) and the bisphosphonate olpadronate reduce the incidence of spinal cord compression in patients with hormone-refractory prostate cancer metastatic to the skeleton. Soerdjbalie-Maikoe V, Pelger RCM, Nijeholt GABL, Arndt JW, Zwinderman AH, Papapoulos SE, Hamdy NAT EUR J NUCL MED MOL IMAGING 2002 29 4 494-498
    • (2002) EUR J NUCL MED MOL IMAGING , vol.29 , Issue.4 , pp. 494-498
    • Soerdjbalie-Maikoe, V.1    Pelger, R.C.M.2    Gabl, N.3    Arndt, J.W.4    Zwinderman, A.H.5    Papapoulos, S.E.6    Hamdy, N.A.T.7
  • 167
    • 0027314987 scopus 로고
    • Strontium-89 as an adjuvant to external beam radiation improves pain relief and delays disease progression in advanced prostate cancer: Results of a randomized controlled trial
    • 1054290
    • 1054290 Strontium-89 as an adjuvant to external beam radiation improves pain relief and delays disease progression in advanced prostate cancer: Results of a randomized controlled trial. Porter AT, McEwan AJ SEMIN ONCOL 1993 20 3 38-43
    • (1993) SEMIN ONCOL , vol.20 , Issue.3 , pp. 38-43
    • Porter, A.T.1    McEwan, A.J.2
  • 168
    • 0038503580 scopus 로고    scopus 로고
    • Role of strontium-89 as adjuvant to palliative external beam radiotherapy is questionable: Results of a double-blind randomized study
    • 1054291
    • 1054291 Role of strontium-89 as adjuvant to palliative external beam radiotherapy is questionable: Results of a double-blind randomized study. Smeland S, Erikstein B, Aas M, Skovlund E, Hess SL, Fossa SD INT J RADIAT ONCOL BIOL PHYS 2003 56 5 1397-1404
    • (2003) INT J RADIAT ONCOL BIOL PHYS , vol.56 , Issue.5 , pp. 1397-1404
    • Smeland, S.1    Erikstein, B.2    Aas, M.3    Skovlund, E.4    Hess, S.L.5    Fossa, S.D.6
  • 169
    • 12444308202 scopus 로고    scopus 로고
    • Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts
    • 1054292
    • 1054292 Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts. Fizazi K, Yang J, Peleg S, Sikes CR, Kreimann EL, Daliani D, Olive M, Raymond KA, Janus TJ, Logothetis CJ, Karsenty G et al CLIN CANCER RES 2003 9 7 2587-2597
    • (2003) CLIN CANCER RES , vol.9 , Issue.7 , pp. 2587-2597
    • Fizazi, K.1    Yang, J.2    Peleg, S.3    Sikes, C.R.4    Kreimann, E.L.5    Daliani, D.6    Olive, M.7    Raymond, K.A.8    Janus, T.J.9    Logothetis, C.J.10    Karsenty, G.11
  • 171
    • 0037025352 scopus 로고    scopus 로고
    • Transforming growth factor-? stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways
    • 1054295
    • 1054295 Transforming growth factor-? stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways. Kakonen SM, Selander KS, Chirgwin JM, Yin JJ, Burns S, Rankin WA, Grubbs BG, Dallas M, Cui Y, Guise TA J BIOL CHEM 2002 277 27 24571-24578
    • (2002) J BIOL CHEM , vol.277 , Issue.27 , pp. 24571-24578
    • Kakonen, S.M.1    Selander, K.S.2    Chirgwin, J.M.3    Yin, J.J.4    Burns, S.5    Rankin, W.A.6    Grubbs, B.G.7    Dallas, M.8    Cui, Y.9    Guise, T.A.10
  • 172
    • 0028799675 scopus 로고
    • Stimulation of endosteal bone formation by systemic injections of recombinant basic fibroblast growth factor in rats
    • 1054296
    • 1054296 Stimulation of endosteal bone formation by systemic injections of recombinant basic fibroblast growth factor in rats. Nakamura T, Hanada K, Tamura M, Shibanushi T, Nigi H, Tagawa M, Fukumoto S, Matsumoto T ENDOCRINOLOGY 1995 136 3 1276-1284
    • (1995) ENDOCRINOLOGY , vol.136 , Issue.3 , pp. 1276-1284
    • Nakamura, T.1    Hanada, K.2    Tamura, M.3    Shibanushi, T.4    Nigi, H.5    Tagawa, M.6    Fukumoto, S.7    Matsumoto, T.8
  • 173
    • 0036638837 scopus 로고    scopus 로고
    • Epidermal growth factor receptor modulation of radiation response: Preclinical and clinical development
    • 1054299
    • 1054299 Epidermal growth factor receptor modulation of radiation response: Preclinical and clinical development. Harari PM, Huang SM SEMIN RADIAT ONCOL 2002 12 3 21-26
    • (2002) SEMIN RADIAT ONCOL , vol.12 , Issue.3 , pp. 21-26
    • Harari, P.M.1    Huang, S.M.2
  • 174
    • 0842265380 scopus 로고    scopus 로고
    • Radiosensitization following EGFR signaling inhibition by erlotinib (Tarceva)
    • 1054302
    • 1054302 Radiosensitization following EGFR signaling inhibition by erlotinib (Tarceva). Chinnaiyan P, Huang S, Armstrong E, Harari PM INT J RADIAT ONCOL BIOL PHYS 2003 57 2 Suppl S294
    • (2003) INT J RADIAT ONCOL BIOL PHYS , vol.57 , Issue.2 SUPPL.
    • Chinnaiyan, P.1    Huang, S.2    Armstrong, E.3    Harari, P.M.4
  • 177
    • 0001368319 scopus 로고
    • Biological investigation with radioactive calcium and strontium. Preliminary report on the use of radioactive strontium in the treatment of metastatic bone cancer
    • 1055004
    • 1055004 Biological investigation with radioactive calcium and strontium. Preliminary report on the use of radioactive strontium in the treatment of metastatic bone cancer. Pecher P UNIV CALIFORNIA PUBLICATIONS PHARMACOL 1942 2 117-149
    • (1942) UNIV CALIFORNIA PUBLICATIONS PHARMACOL , vol.2 , pp. 117-149
    • Pecher, P.1
  • 178
    • 4043067462 scopus 로고    scopus 로고
    • Comparative clinical efficacy and safety of phosphorus-32 and strontium-89 in the palliative treatment of metastatic bone pain: Results of an IAEA coordinated research Project
    • 1055033
    • 1055033 Comparative clinical efficacy and safety of phosphorus-32 and strontium-89 in the palliative treatment of metastatic bone pain: Results of an IAEA coordinated research Project. Fettich J, Padhy A, Nair N, Morales R,Tamumihardja M, Riccabonna G, Nair G WORLD J NUCLEAR MED 2003 2 226-231
    • (2003) WORLD J NUCLEAR MED , vol.2 , pp. 226-231
    • Fettich, J.1    Padhy, A.2    Nair, N.3    Morales, R.4    Tamumihardja, M.5    Riccabonna, G.6    Nair, G.7
  • 180
    • 0022897120 scopus 로고
    • Iodine-131-labeled diphosphonates for palliative treatment of bone metastases: II. Preliminary clinical results with iodine-131 BDP3
    • 1055052 Iodine-131-labeled diphosphonates for palliative treatment of bone metastases: II. Preliminary clinical results with iodine-131 BDP3. Eisenhut M, Berberich R, Kimmig B, Oberhausen E J NUCL MED 1986 27 8 1255-1261 (Pubitemid 17030120)
    • (1986) Journal of Nuclear Medicine , vol.27 , Issue.8 , pp. 1255-1261
    • Eisenhut, M.1    Berberich, R.2    Kimmig, B.3    Oberhausen, E.4
  • 181
    • 0033774529 scopus 로고    scopus 로고
    • Treatment of bone metastases of prostate cancer with strontium-89 chloride: Efficacy in relation to the degree of bone involvement
    • 1055065
    • 1055065 Treatment of bone metastases of prostate cancer with strontium-89 chloride: Efficacy in relation to the degree of bone involvement. Kraeber-Bodere F, Campion L, Rousseau C, Bourdin S, Chatal JF, Resche I EUR J NUCL MED 2000 27 10 1487-1493
    • (2000) EUR J NUCL MED , vol.27 , Issue.10 , pp. 1487-1493
    • Kraeber-Bodere, F.1    Campion, L.2    Rousseau, C.3    Bourdin, S.4    Chatal, J.F.5    Resche, I.6
  • 182
    • 0034922587 scopus 로고    scopus 로고
    • A multicentre observational study of radionuclide therapy in patients with painful bone metastases of prostate cancer
    • DOI 10.1007/s002590100533
    • 1055067 A multicentre observational study of radionuclide therapy in patients with painful bone metastases of prostate cancer. Dafermou A, Colamussi P, Giganti M, Cittanti C, Bestagno M, Piffanelli A EUR J NUCL MED 2001 28 7 788-798 (Pubitemid 32662540)
    • (2001) European Journal of Nuclear Medicine , vol.28 , Issue.7 , pp. 788-798
    • Dafermou, A.1    Colamussi, P.2    Giganti, M.3    Cittanti, C.4    Bestagno, M.5    Piffanelli, A.6
  • 185
    • 0017281151 scopus 로고
    • Chemotherapy of advanced carcinoma of the prostate with 5-fluorouracil, cyclophosphamide and adriamycin
    • 1055309
    • 1055309 Chemotherapy of advanced carcinoma of the prostate with 5-fluorouracil, cyclophosphamide and adriamycin. Merrin C, Etra W, Wajsman Z, Baumgartner G, Murphy G J UROL 1976 115 1 86-88
    • (1976) J UROL , vol.115 , Issue.1 , pp. 86-88
    • Merrin, C.1    Etra, W.2    Wajsman, Z.3    Baumgartner, G.4    Murphy, G.5
  • 187
    • 71249083594 scopus 로고    scopus 로고
    • 1056922 COMPANY COMMUNICATION Algeta ASA November 06
    • 1056922 Drug development update: Alpharadin. COMPANY COMMUNICATION Algeta ASA 2009 November 06
    • (2009) Drug Development Update: Alpharadin


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