Palliative radiotherapy in the treatment of skeletal metastases

European Journal of Pain

Volumn 6, Issue 5, 2002, Pages 323-330

  Saarto, Tiina ^a   Janes, Rita ^a   Tenhunen, Mikko ^a   Kouri, Mauri ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Bone metastases neoplasm; Pain; Palliative care; Radiotherapy

Indexed keywords

SAMARIUM 153; STRONTIUM 89;

BONE METASTASIS; BONE PAIN; CANCER RADIOTHERAPY; COST EFFECTIVENESS ANALYSIS; HUMAN; OSTEOLYSIS; PATHOLOGIC FRACTURE; PRIORITY JOURNAL; REVIEW; SPINAL CORD COMPRESSION;

EID: 0036380479     PISSN: 10903801     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1090-3801(02)00028-9     Document Type: Review

References (38)

1. Andreasson I, Petren-Mallmin M, Strang P, Nilsson S, Nyman R, Hemmingsson A. Diagnostic methods in planning palliation of spinal metastases. Anticancer Res 1990; 10: 731-734.
2. Arcangeli G, Micheli A, Arcangeli G, Giannarelli D, La Pasta O, Tollis A et al. The responsiveness of bone metastases to radiotherapy; The effect of site, histology and radiation dose on pain relief. Radiother Oncol 1989; 14: 95-101.
3. Bendosef E, Porter AT. Radioisotopes in the treatment of bone metastases. Ann Med 1997; 29: 31-35.
4. Bonarico BC, Rubin P. Nonunion of pathologic fracture after radiation therapy. Radiology 1967; 88: 889-898.
5. Cleeland CS, Gonin R, Hatfield AK, Edmonson JH, Blum RH, Stewart JA et al. Pain and its treatment in outpatients with metastatic caner. New Engl J Med 1994; 330(9): 592-596.
6. Coleman RE. Skeletal complications of malignancy. Cancer 1997; 80(Suppl): 1588-1594.
7. Elte JWF, Bijvoet OLM, Cleton FJ, Van Oosterom AT, Sleeboom HP. Osteolytic bone metastases in breast carcinoma pathogenesis, morbidity and bisphosphonate treatment. Eur J Clin Oncol 1996; 22: 493-500.
8. Gainor BJ, Buchert P. Fracture healing in metastatic bone disease. Clin Orthop 1983; 178: 297-302.
9. Galasko CS. Skeletal metastages. Clin Orthop 1986; 210: 18-30.
10. Garmatis CJ, Chu FCH. The effectiveness of radiation therapy in the treatment of bone metastases from breast cancer. Radiology 1978; 126: 235-237.
11. Harrington KD. Impending pathologic fractures from metastatic malignancy: evaluation and management. Instr Course Lect 1986; 35: 357-381.
12. Hoskin PJ. Scientific and clinical aspects of radiotherapy in the relief of bone pain. Cancer Surv 1988; 7: 69-86.
13. Jeremic B, Shibamoto Y, Igrutinovic I. Single 4 Gy re-irradiation for painful bone metastasis following single fraction radiotherapy. Radiother Oncol 1999; 52: 123-127.
14. Kamholz R, Sze G. Current imaging in spinal metastatic disease. Sem Oncol 1991; 18: 158-169.
15. Larue F, Colleau SM, Brasseur L, Cleeland CS. Multicentre study of cancer pain and its treatment in France. Br Med J 1995; 310(6986): 1034-1039.
16. Loblaw DA, Laperriere NJ. Emergency treatment of malignant extradural spinal cord compression: an evidence-based guideline. J Clin Oncol 1998; 16: 1613-1624.
17. Macbeth FR, Wheldon TE, Girling DJ, Stephens RJ, Machin D, Bleehen NM, et al., for the Medical Research Council Lung Cancer Working Party. Radiation myelopathy: estimates of risk in 1048 patients in three randomized trails of palliative radiotherapy for non-small-cell lung cancer. Clin Oncol 1996; 8: 176-181.
18. McQuay HJ, Collins SL, Moore RA. Radiotherapy for painful bone metastases: a systemic review. Clin Oncol 1997; 9: 150-154.
19. Mercadante S. Malignant bone pain: pathophysiology and treatment. Pain 1997; 69: 1-18.
20. Payne R. Mechanisms and management of bone pain. Cancer 1997; 80(Suppl): 1608-1613.
21. Pigott KH, Baddeley H, Maher EJ. Pattern of disease in spinal cord compression on MRI Scan and implications for treatment. Clin Oncol 1994; 6: 7-10.
22. Porter AT, McEwan JB, Powe JE, Reid R, McGowan DG, Lukka H et al. Results of a randomized phase-III trial to evaluate the efficacy of strontium-89 adjuvant to local field external beam irradiation in the management of endocrine resistant meatastatic prostate cancer. Int J Radiat Oncol Biol Phys 1993; 25: 805-813.
23. Poulsen HS, Nielsen OS, Klee M, Rotrh M. Palliative irradiation of bone metastases. Cancer Treat Rev 1989; 16: 41-48.
24. Poulter CA, Cosmatos DH, Rubin P, Urtasun R, Cooper JS, Kuske RR et al. A report of RTOG 8206: a phase III study of whether the addition of single dose hemibody irradiation to standard fractionated local field irradiation is more effective than local field irradiation alone in the treatment of symptomatic osseous metastases. Int J Radiat Oncol Biol Phys 1992; 23: 207-214.
25. Price P, Hoskin PJ, Easton D, Austin D, Palmer G, Yarnold JR. Prospective randomised trial of single and multifraction radiotherapy schedules in the treatment of painful bony metastases. Radiother Oncol 1986; 6: 247-255.
26. Quilty PM, Kirk D, Bolger JJ, Dearnaley DP, Lewington VJ, Mason MD et al. A comparison of the palliative effects of strontium-89 and external beam radiotherapy in metastatic prostate cancer. Radiother Oncol 1994; 31: 33-40.
27. Ratanatharathorn V, Powers WE, Moss WT, Perez CA. Bone Metastasis: review and critical analysis of random allocation trials of local field treatment. Int J Radiat Oncol Biol Phys 1999; 44: 1-18.
28. Rodichok LD, Ruckdeschel JC, Harper GR, Cooper G, Prevosti L, Fernando L et al. Early detection and treatment of spinal epidural metastases: the role of myelography. Ann Neurol 1986; 20: 696-702.
29. Sim FH, Frassica FJ, Frassica DA. Metastatic bone disease: current concepts of clinicopathophysiolgy and modern surgical treatment. Ann Acad Med 1992; 21: 274-279.
30. Salazar OM, Rubin P, Hendrickson FR, Komaki R, Poulter C, Newall J et al. Single-dose half-body irradiation for palliation of multiple bone metastases from solid tumors. Cancer 1986; 58: 29-36.
31. Schultheiss TE, Stephens LC. Permanent radiation myelopathy. Br J Radiol 1992; 65: 737-753.
32. Serafini AN. Samarium Sm-153 lexidronam for the palliation of bone pain associated with metastases. Cancer 2000; 88: 2934-2939.
33. Sorensen PS, Borgesen SE, Rohde K, Rasnusson B, Bach F, Boge-Rasmussen T et al. Metastatic epidural spinal cord compression. Results of treatment and survival. Cancer 1990; 60: 1502-1508.
34. Steenland E, Leer J, van Houwelingen H, Post WJ, van den Hout WB, Kievit J et al. The effect of a single fraction compared to multiple fractions on painful bone metastases: a global analysis of the Dutch bone metastases study. Radiother Oncol 1999; 52: 101-109.
35. The Bone Pain Trial Working Party. 8 Gy single fraction radiotherapy for the treatment of metastatic skeletal pain: randomised comparison with a multifraction schedule over 12 months of patient follow-up. Radiother Oncol 1999; 52: 111-121.
36. Townsend PW, Smalley SR, Cozad SC, Rosenthal HG, Hassanein RES. Role of postoperative therapy after stabilization of fractures caused by metastatic disease. Int J Radiat Oncol Biol Phys 1995; 31: 43-49.
37. Tubiana-Hulin M. Incidence, prevalence and distribution of bone metastases. Bone 1991; 12(Suppl 1): S9-S10.
38. Vainio A, Auvinen A. Prevalence of symptoms among patients with advanced cancer: an international collaborative study. J Pain Symptom Manage 1996; 12: 3-10.