223Ra for endoradiotherapeutic applications prepared from an immobilized 227Ac/227Th source

Radiochimica Acta

Volumn 89, Issue 37165, 2001, Pages 661-666

  Henriksen, Gjermund ^a,b   Hoff, Per ^a   Alstad, Jorolf ^a   Larsen, Roy H ^a,b  

^a UNIVERSITY OF OSLO   (Norway)

^b ATI AS   (Norway)

Author keywords

223Ra; 227Ac; 227Th; Alpha particle emitter; Radionuclide generator; Targeted radiotherapy

Indexed keywords

ACTINIUM; ACTINIUM 227; ISOTOPE; PHOSPHONIC ACID DERIVATIVE; RADIUM; RADIUM 223; THORIUM; THORIUM 227; UNCLASSIFIED DRUG;

ALPHA RADIATION; ARTICLE; CHROMATOGRAPHY; DRUG SYNTHESIS; HALF LIFE TIME; PURIFICATION; RADIOACTIVITY; RADIOISOTOPE DECAY; RADIOTHERAPY;

EID: 0034768348     PISSN: 00338230     EISSN: None     Source Type: Journal    
DOI: 10.1524/ract.2001.89.10.661     Document Type: Article

References (32)

1. Zalutsky, M. R., Akabani, G., Cokgor, I., Friedman, H. S., Coleman, R. E., Friedman, A. H., McLendon, R. E., Bigner, D. D.: Astatine-211 labeled chimeric anti-tenascin antibody: Phase I trial in brain tumor resection cavity patients. Eur. J. Nuc. Med. 26, 651 (1999).
2. Sgouros, G., Ballangrud, Å. M., Jurcic, J. G., McDevitt, M. R. Humm, J. L., Erdi, Y. E. Mehta, B. M. Finn, R. D. Larson, S. M., Scheinberg, D. A.: Pharmacokinetics and dosimetry of an alpha-particle emitter labeled antibody: Bi-213-HuM195 (anti-CD33) in patients with leukemia. J. Nucl. Med. 40, 1935 (1999).
3. Fisher, D. R., Harty R.: The microdosimetry of lymphocytes irradiated by alpha particles. Int. J. Radiat. Biol. 41, 315 (1982).
4. Humm, J. L., Roeske, J. C., Fisher, D. R., Chen, G. T. Y.: Microdosimetric concepts in radioimmunotherapy. Med. Phys. 20, 535 (1993).
5. Mattes, M. J.: Pharmacokinetics of antibodies and their radiolabels. In: Cancer therapy with radiolabeled antibodies. (Goldenberg, D. M. ed.) CRC Press (1995).
6. Feinendegen, L. E., McClure, J. J.: Alpha emitters for medical therapy-Workshop of the United States department of energy. Radiat. Res. 148, 195 (1997).
7. McDewitt, M. R., Sgouros, G., Finn, R. D. Humm, J. L., Jurcic, J. G., Larson, S. M., Scheinberg D. A.: Radioimmunotherapy with alpha-emitting nuclides. Eur. J. Nucl. Med. 25, 1341 (1998).
8. Garret, R.: Bone destruction in cancer. Semin. Oncol. 72, 3433 (1993).
9. Nielsen, O. S., Munro, A. J., Tannock, I. F.: Bone metastases: Pathophysiology and management policy. J. Clin. Oncol. 9, 509 (1991).
10. Atkins, H. L.: Overview of nuclides for bone palliation. Appl. Radiat. Isot. 49, 277 (1998).
11. Atkins, H. L., Mausner, L. F., Srivastava, S. C., Meinken, G. E., Cabahug, G. E., D'Allesandro, T.: Tin-117m(4+) DTPA for palliation of pain from osseous metastases. A pilot study. J. Nucl. Med. 36, 725 (1995).
12. Hassfjell, S. P., Bruland, Ø. S., Hoff, P.: Bi-212-DOTMP: An alpha particle emitting bone-seeking agent for targeted radiotherapy. Nuc. Med. Biol. 24, 231 (1997).
13. Larsen, R. H., Murud, K. M., Akabani, G., Hoff, P., Bruland, Ø. S., Zalutsky, M. R.: At-211-and I-131-labeled bisphosphonates with high in vivo stability and bone accumulation. J. Nuc. Med. 40, 1197 (1999).
14. Gmelin Handbuch der Anorganischen Chemie. Actinium. Suppl. Vol. 1, Springer Verlag (1981) p. 83.
15. Taylor, D.M.: The metabolism of Actinium in the rat. Health Phys. 19, 411 (1970).
16. Newton, D., Brown D. A.: The long term retention of systemic Protactinium-231 and Actinium-227. Health Phys. 27, 459 (1974).
17. National Institute of Standards and Technology. NIST Technical Note 1297, WECC-Doc. 19–1990 (1990).
18. Burnett, W. C., Yeh, C. C.: Separation of Protactinium from geochemical materials via extraction chromatography. Radioact. Radiochem. 6, 22 (1995).
19. 225Ac. Radiochim. Acta. 79, 141 (1997).
20. Horwitz, E. P., Chiarizia, R., Dietz, M. L., Diamond H.: Separation and preconcentration of actinides from acidic media by extraction chromatography. Anal. Chim. Acta. 281, 361 (1993).
21. Internation Commision on Radiation Protection. ICRP publication 61. Annual limits on intake of radionuclides by workers based on the 1990 recommendation. Pergamon Press (1991).
22. Chiarizia, R., Horwitz, E. P.: Radiolytic stability of some recently developed ion exchange and extraction chromatographic resins containing diphosphonic acid groups. Solvent Extraction Ion. Exch. 18, 109 (2000).
23. Danon, J.: Adsorption of thorium by anion exchange resins from nitric acid media. J. Am. Chem. Soc. 78, 5953 (1956).
24. Faris, J. P., Buchanan, R. F.: Anion exchange characteristics of elements in nitric acid medium. Anal. Chem. 36, 1157 (1964).
25. 227Ac und seine Folgeprodukte. Radiochim. Acta. 9, 181 (1968).
26. Gmelin Handbuch der Anorganischen Chemie. Actinium. Suppl. Vol. 1, Springer Verlag (1981) p. 86, p. 98.
27. 227Ac. Can. J. Chem. 37, 1094 (1959).
28. Burnett, W., Cable, P.: Determination of Radium-228 in natural waters using extraction chromatographic resins. Radioact. Radiochem. 6, 36 (1995).
29. Chiarizia, R., Horwitz, E. P., Rickert, P. G., Herlinger, A. W.: Metal Extraction by alkyl substituted diphosphonic acids. Part I, P,P′-Di(2-ethylhexyl)methanediphosphonic acid. Solvent Extraction Ion. Exch. 14, 773 (1996).
30. Horwitz, E. P., Bloomquist, C. A. A.: Chemical separation for super-heavy element searches in irradiated uranium targets. Inorg. Nucl. Chem. 37, 425 (1975).
31. 224Ra for therapy of ankylosing spondylitis. Health Phys. 35, 21 (1978).
32. Ekström, P., Spanier, L.: The ENSDF radioactivity database for IBM-PC and computer network access. Department of Physics, University of Lund Sweden.