Reduced post-operative neutrophil activation in liver transplant recipients suffering from post-hepatitic cirrhosis

Clinical Transplantation

Volumn 23, Issue 6, 2009, Pages 921-929

  Jüttner, Björn ^a   Younes, Alan ^a   Weißig, Annette ^a   Ahrens, Jörg ^a   Becker, Thomas ^b   Scheinichen, Dirk ^a  

^a Department of Anesthesiology ^*  (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Flow cytometry; Liver transplantation; Neutrophils; Oxidative stress; Respiratory burst

Indexed keywords

BASILIXIMAB; CYCLOSPORIN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; HYDROGEN PEROXIDE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; MYELOPEROXIDASE; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA; PEROXIDASE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENZYME BLOOD LEVEL; FEMALE; GRAFT RECIPIENT; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; LIVER CIRRHOSIS; LIVER DISEASE; LIVER TRANSPLANTATION; MALE; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REPERFUSION; RESPIRATORY BURST; THROMBOCYTE ACTIVATION; BLOOD; COMPARATIVE STUDY; COMPLICATION; FOLLOW UP; HEPATITIS C; MIDDLE AGED; NEUTROPHIL; PHYSIOLOGY; PROGNOSIS; PROSPECTIVE STUDY;

ADULT; FEMALE; FOLLOW-UP STUDIES; HEPATITIS C; HUMANS; HYDROGEN PEROXIDE; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; NEUTROPHIL ACTIVATION; NEUTROPHILS; PEROXIDASE; POSTOPERATIVE PERIOD; PROGNOSIS; PROSPECTIVE STUDIES;

EID: 71149115460     PISSN: 09020063     EISSN: 13990012     Source Type: Journal    
DOI: 10.1111/j.1399-0012.2009.01016.x     Document Type: Article

References (27)

1. Navasa M, Rimola A, Rodés J. Bacterial infections in liver disease. Semin Liver Dis 1997, 17:323.
2. D'Odorico A, Melis A, Baragiotta A, Martines D, Naccarato R, Floreani A. Oxygen-derived free radical production by peripheral blood neutrophils in chronic cholestatic liver diseases. Hepatogastroenterology 1999, 46:1831.
3. Panasiuk A, Wysocka J, Maciorkowska E. Phagocytic and oxidative burst activity of neutrophils in the end stage of liver cirrhosis. World J Gastroenterol 2005, 28:7661.
4. Mookerjee RP, Stadlbauer V, Lidder S. Neutrophil dysfunction in alcoholic hepatitis superimposed on cirrhosis is reversible and predicts the outcome. Hepatology 2007, 46:831.
5. Singh N, Gayowski T, Wagener MM, Marino IR. Increased infections in liver transplant recipients with recurrent hepatitis C virus hepatitis. Transplantation 1996, 61:402.
6. Gabardi S, Kubiak DW, Chandraker AK, Tullius SG. Invasive fungal infections and antifungal therapies in solid organ transplant recipients. Transpl Int 2007, 20:993.
7. Rothe G, Oser A, Valet G. Dihydrorhodamine 123: a new flow cytometric indicator for respiratory burst activity in neutrophil granulocytes. Naturwissenschaften 1988, 75:354.
8. Jüttner B, Gehrmann A, Breitmeier D. Renal transplantation normalized hydrogen peroxide production of neutrophils within the first day. Am J Nephrol 2008, 28:531.
9. Jüttner B, Kröplin J, Coldewey SM. Unsaturated long-chain fatty acids induce the respiratory burst of human neutrophils and monocytes in whole blood. Nutr Metab (Lond) 2008, 5:19.
10. Scheinichen D, zu Vilsendorf AM, Weissig A. Reduced P-selectin expression on circulating platelets after prolonged cold preservation in renal transplantation. Clin Transplant 2003, 17:444.
11. Fiuza C, Salcedo M, Clemente G, Tellado JM. In vivo neutrophil dysfunction in cirrhotic patients with advanced liver disease. J Infect Dis 2000, 182:526.
12. Wang Y, Liu Y, Han R. Hemostatic variation during perioperative period of orthotopic liver transplantation without venovenous bypass. Thromb Res 2008, 122:161.
13. Kóbori L, Sárváry E, Nemes B. The role of oxidative stress and arterial blood supply in the transplanted liver function. Orv Hetil 2003, 144:2219.
14. Brown KE, Brunt EM, Heinecke JW. Immunohistochemical detection of myeloperoxidase and its oxidation products in Kupffer cells of human liver. Am J Pathol 2001, 159:2081.
15. Pesonen EJ, Höckerstedt K, Mäkisalo H. Transhepatic neutrophil and monocyte activation during clinical liver transplantation. Transplantation 2000, 69:1458.
16. Zhao J, Jüttner B, Scheinichen D, Jaeger K, Heine J, Piepenbrock S. Respiratory burst activity of polymorphonuclear cells is dependent on the cell preparation technique. Acta Anaesthesiol Scand 2003, 47:702.
17. Okaya T, Lentsch AB. Cytokine cascades and the hepatic inflammatory response to ischemia and reperfusion. J Invest Surg 2003, 16:141.
18. Inwald DP, Kirkham FJ, Peters MJ. Platelet and leucocyte activation in childhood sickle cell disease: association with nocturnal hypoxaemia. Br J Haematol 2000, 111:474.
19. Peters MJ, Dixon G, Kotowicz KT, Hatch DJ, Heyderman RS, Klein NJ. Circulating platelet-neutrophil complexes represent a subpopulation of activated neutrophils primed for adhesion, phagocytosis and intracellular killing. Br J Haematol 1999, 106:391.
20. Kubala L, Cíz M, Vondrácek J. Peri- and post-operative course of cytokines and the metabolic activity of neutrophils in human liver transplantation. Cytokine 2001, 16:97.
21. Jaeschke H. Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Am J Physiol Gastrointest Liver Physiol 2003, 284:G15.
22. Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest 2003, 111:1805.
23. Pulitanò C, Aldrighetti L, Arru M. Preoperative methylprednisolone administration maintains coagulation homeostasis in patients undergoing liver resection: importance of inflammatory cytokine modulation. Shock 2007, 28:401.
24. Pulitanò C, Guzzetti E, Arru M, Ferla G, Aldrighetti L. In defense of the administration of perioperative steroids in liver transplantation. Liver Transpl 2008, 14:124.
25. Kurokawa T, Nonami T, Kobayashi H. Inhibition by cyclosporine of the production of superoxide radicals. N Engl J Med 1992, 326:840.
26. Krötz F, Keller M, Derflinger S. Mycophenolate acid inhibits endothelial NAD(P)H oxidase activity and superoxide formation by a Rac1-dependent mechanism. Hypertension 2007, 49:201.
27. Garcia-Retortillo M, Forns X, Feliu A. Hepatitis C virus kinetics during and immediately after liver transplantation. Hepatology 2002, 35:680.