Reduced P-selectin expression on circulating platelets after prolonged cold preservation in renal transplantation

Clinical Transplantation

Volumn 17, Issue 5, 2003, Pages 444-450

  Scheinichen, Dirk ^a   Meyer zu Vilsendorf, Andreas ^a   Weißig, Annette ^a   Bornscheuer, Albrecht ^a   Becker, Thomas ^a   Juettner, Bjoern ^a   Mahr, Karl Heinz ^a   Heine, Joern ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Cold ischemia; Flow cytometry; Kidney transplantation; Leukocyte platelet complexes; Platelet activation

Indexed keywords

CYCLOSPORIN; FIBRINOGEN RECEPTOR; PADGEM PROTEIN; STEROID;

ADULT; ARTICLE; BLEEDING TENDENCY; CELL INTERACTION; CLINICAL ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYOPRESERVATION; ENDOTHELIUM CELL; FEMALE; FLOW CYTOMETRY; GRAFT PRESERVATION; GRAFT SURVIVAL; GRANULOCYTE; HUMAN; INFLAMMATION; KIDNEY FAILURE; KIDNEY GRAFT; KIDNEY ISCHEMIA; KIDNEY TRANSPLANTATION; LEUKOCYTE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REPERFUSION INJURY; THROMBOCYTE; THROMBOCYTE DYSFUNCTION; TIME; UREMIA; VOLUNTEER;

ANTIGENS, CD45; BLOOD PLATELETS; COLD; FEMALE; FLOW CYTOMETRY; HUMANS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; LEUKOCYTES; MALE; MIDDLE AGED; ORGAN PRESERVATION; P-SELECTIN; PEPTIDE FRAGMENTS; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PLATELET MEMBRANE GLYCOPROTEIN IIB; TIME FACTORS;

EID: 0141955823     PISSN: 09020063     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0012.2003.00073.x     Document Type: Article

References (12)

1. Bazilinski N, Shaykh M, Dunea G, et al. Inhibition of platelet function by uremic middle molecules. Nephron 1985: 40: 423.
2. Sreedhara R, Itagaki I, Hakim RM. Uremic platelets have decreased shear-induced platelet aggregation mediated by decreased availability of glycoprotein IIb-IIIa receptors. Am J Kidney Dis 1996: 27: 355.
3. Gawaz MP, Mujais SK, Schmidt B, Gurland HJ. Platelet-leukocyte aggregation during hemodialysis. Kidney Int 1994: 46: 489.
4. Diaz-Ricart M, Estebanell E, Cases A, et al. Abnormal platelet cytoskeletal assembly in hemodialyzed patients results in deficient tyrosine phosphorylation signaling. Kidney Int 2000: 57: 1905.
5. Reverter JC, Escolar G, Sanz C, et al. Platelet activation during hemodialysis measured through exposure of p-selectin: analysis by flow cytometric and ultrastructural techniques. J Lab Clin Med 1994: 124: 79.
6. Ojo AO, Wolfe RA, Held PJ, Port FK, Schmouder RL. Delayed graft function: risk factors and implications for renal allograft survival. Transplantation 1997: 63: 968.
7. Koo DDH, Welsh KI, Roake JA, Morris PJ, Fuggle SV. Ischemia/reperfusion injury in human kidney transplantation. An immunohistochemical analysis of changes after reperfusion. Am J Pathol 1998: 153: 557.
8. Kozek-Langenecker SA, Masaki T, Mohammad H, Green W, Mohammad SF, Cheung A. Fibrinogen fragments and platelet dysfunction in uremia. Kidney Int 1999: 56: 299.
9. Nakamura Y, Tomura S, Tachibana K, Chida Y, Marumo F. Enhanced fibrinolytic activity during the course of hemodialysis. Clin Nephrol 1992: 38: 90.
10. Singbartl K, Forlow SB, Ley K. Platelet, but not endothelial, P-selectin is critical for neutrophil-mediated acute postischemic renal failure. FASEB: 2001: 2337.
11. Fuller T, Sattler B, Binder L, Vetterlein F, Ringe B, Lorf T. Reduction of severe ischemia/reperfusion injury in rat kidney grafts by a soluble p-selectin glycoprotein ligand. Transplantation 2000: 27: 216.
12. Peters MJ, Dixon G, Kotowicz KT, Hatch DJ, Heyderman RS, Klein NJ. Circulating platelet-neutrophil complexes represent a subpopulation of activated neutrophils primed for adhesion, phagocytosis and intracellular killing. Br J Haematol 1999: 106: 391.