Ferritin Heavy Chain (FHC) is Up-regulated in Papillomavirus-Associated Urothelial Tumours of the Urinary Bladder in Cattle

Journal of Comparative Pathology

Volumn 142, Issue 1, 2010, Pages 9-18

  Roperto, S ^a   Borzacchiello, G ^a   Brun, R ^a   Costanzo, F ^b   Faniello, M C ^b   Raso, C ^b   Rosati, A ^c   Russo, V ^a   Leonardi, L ^d   Saracino, D ^e   Turco, M C ^c   Urraro, C ^a   Roperto, F ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^c UNIVERSITY OF SALERNO   (Italy)

^d UNIVERSITY OF PERUGIA   (Italy)

^e Azienda Sanitaria Locale (ASL)   (Italy)

Author keywords

cattle; ferritin heavy chain; papillomavirus; urinary bladder; urothelial tumour

Indexed keywords

FERRITIN; FERRITIN HEAVY CHAIN; ONCOPROTEIN; PROTEIN E5; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BLADDER; BOVINE PAPILLOMAVIRUS TYPE 2; CATTLE DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; UPREGULATION; UROGENITAL TRACT TUMOR; VIRUS INFECTION;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CATTLE; CATTLE DISEASES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FERRITINS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOPRECIPITATION; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PAPILLOMAVIRUS INFECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, NUCLEIC ACID; UP-REGULATION; URINARY BLADDER NEOPLASMS;

BOS; BOVINAE; BOVINE PAPILLOMAVIRUS TYPE 2; PAPILLOMAVIRIDAE; PTERIDIUM AQUILINUM;

EID: 71149093113     PISSN: 00219975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcpa.2009.05.009     Document Type: Article

References (47)

1. Aung W., Hasegawa S., Furukawa T., and Saga T. Potential role of ferritin heavy chain in oxidative stress and apoptosis in human mesothelial and mesothelioma cells: implications for asbestos-induced oncogenesis. Carcinogenesis 28 (2007) 2047-2052
2. Borzacchiello G., Iovane G., Marcante M.L., Poggiali F., Roperto F., et al. Presence of bovine papillomavirus type 2 DNA and expression of the viral oncoprotein E5 in naturally occurring urinary bladder tumours in cows. Journal of General Virology 84 (2003) 2921-2926
3. Borzacchiello G., and Roperto F. Bovine papillomaviruses, papillomas and cancer in cattle. Veterinary Research 39 (2008) 45-63
4. Boult J., Roberts K., Brookes M.J., Hughes S., Bury J.P., et al. Overexpression of cellular iron import proteins is associated with malignant progression of esophageal adenocarcinoma. Clinical Cancer Research 14 (2008) 379-387
5. Brookes M.J., Boult J., Roberts K., Cooper B.T., Hotchin N.A., et al. A role for iron in Wnt signalling. Oncogene 27 (2008) 966-975
6. Brookes M.J., Hughes S., Turner F.E., Reynolds G., Sharma N., et al. Modulation of iron transport proteins in human colorectal carcinogenesis. Gut 55 (2006) 1449-1460
7. Bubici C., Papa S., Pham C.G., Zazzeroni F., and Franzoso G. The NF-κB-mediated control of ROS and JNK signaling. Histology and Histopathology 21 (2006) 69-80
8. Campo M.S., Jarrett W.F.H., Barron R.J., O'Neil B.W., and Smith K.T. Association of bovine papillomavirus type 2 and bracken fern with bladder cancer in cattle. Cancer Research 52 (1992) 6898-6904
9. Campo M.S. Animal models of papillomavirus pathogenesis. Virus Research 89 (2002) 249-261
10. Cardoso C.S., Araújo H.C., Cruz E., Afonso A., Mascarenhas C., et al. Haemochromatosis gene (HFE) mutations in viral-associated neoplasia: linkage to cervical cancer. Biochemical and Biophysical Research Communications 341 (2006) 232-238
11. De Domenico I., McVey Ward D., and Kaplan J. Regulation of iron acquisition and storage: consequences for iron-linked disorders. Nature Reviews. Molecular Cell Biology 9 (2008) 72-81
12. Drakesmith H., Chen N., Ledermann H., Screaton G., Townsend A., et al. HIV1 Nef downregulates the hemochromatosis protein HFE, manipulating cellular homeostasis. Proceedings of the National Academy Sciences the United States of America 102 (2005) 11017-11022
13. Drakesmith H., and Prentice A. Viral infection and iron metabolism. Nature Reviews. Microbiology 6 (2008) 541-552
14. Du J., Chen G.G., Vlantis A.C., Xu H., Tsang R.K.Y., et al. The nuclear localization of NF-κB and p53 is positively correlated with HPV16 E7 level in laryngeal squamous cell carcinoma. Journal of Histochemistry and Cytochemistry 53 (2003) 533-539
15. Galaris D., Skiada V., and Barbouti A. Redox signaling and cancer: the role of "labile" iron. Cancer Letters 266 (2008) 21-29
16. Gu J.M., Lim S.O., Oh S.J., Yoon S.M., Seong J.K., et al. HBx modulates iron regulatory protein 1-mediated iron metabolism via reactive oxygen species. Virus Research 133 (2008) 167-177
17. Harrison P.M., and Arosio P. The ferritins: molecular properties, iron storage function and cellular regulation. Biochimica et Biophysica Acta 1275 (1996) 161-203
18. James M.A., Lee J.H., and Klingelhutz A.J. Human papillomavirus type 16 E6 activates NF-κB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner. Journal of Virology 80 (2006) 5301-5307
19. Klaus A., and Birchmeier W. Wnt signaling and its impact on development and cancer. Nature Reviews. Cancer 8 (2008) 387-398
20. Kwak E.L., Larochelle D.A., Beaumont C., Torti S.V., and Torti F.M. Role for NF-kappa B in the regulation of ferritin H by tumour necrosis factor-alpha. Journal of Biological Chemistry 270 (1995) 15285-15293
21. Kwok J.C., and Richardson D.R. The iron metabolism of neoplastic cells: alterations that facilitate proliferation?. Critical Reviews in Oncology/Hematology 42 (2002) 65-78
22. Laham N., and Ehrlich R. Manipulation of iron to determine survival - competition between host and pathogen. Immunology Research 30 (2004) 15-28
23. Lawson D.M., Treffry A., Artymiuk P.J., Harrison P.M., Yewdall S.J., et al. Identification of the ferroxidase centre in ferritin. FEBS Letters 254 (1989) 207-210
24. Li R., Luo C., Mines M., Zhang J., and Fan G.-H. Chemokine CXCL12 induces binding of ferritin heavy chain to the chemokine receptor CXCR4, alters CXCR4 signaling, and induces phosphorylation and nuclear translocation of ferritin heavy chain. Journal of Biological Chemistry 281 (2006) 37616-37727
25. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 (2001) 402-408
26. Lopez-Beltran A., Sauter G., Gasser T., Hartmann A., Schmitz-Dräger B.J., et al. Infiltrating urothelial carcinoma. In: Eble J.N., Sauter G., Epstein J.L., and Sesterhenn I.A. (Eds). Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs (2004), IARC Press, Lyon 93-109
27. Newlands C., Houston D.M., and Vasconcelos D.Y. Hyperferritinemia associated with malignant histiocytosis in a dog. Journal of the American Veterinary Medical Association 205 (1994) 849-851
28. Orino K., Harada S., Natsuhori M., Takehara K., and Watanabe K. Kinetic analysis of bovine spleen apoferritin and recombinant H and L chain homopolymers: iron uptake suggests early stage H chain ferroxidase activity and second stage L chain cooperation. Biometals 17 (2004) 29-134
29. Orino K., and Watanabe K. Molecular, physiological and clinical aspects of the iron storage protein ferritin. Veterinary Journal 178 (2008) 191-201
30. Otten N., von Tscharner C., Lazary S., Antczak D.F., and Gerber H. DNA of bovine papillomavirus type 1 and 2 in equine sarcoids: PCR detection and direct sequencing. Archives of Virology 132 (1993) 121-131
31. Pamukcu A.M., Price J.M., and Bryan G.T. Naturally occurring and bracken fern-induced bovine urinary bladder tumours. Veterinary Pathology 13 (1976) 110-122
32. Pham C.G., Bubici C., Zazzeroni F., Papa S., Jones J., et al. Ferritin heavy chain upregulation by NF-κB inhibits TNFα-induced apoptosis by suppressing reactive oxygen species. Cell 119 (2004) 529-542
33. Recalcati S., Invernizzi P., Arosio P., and Cairo G. New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity. Journal of Autoimmunity 30 (2008) 84-89
34. Reis K., Hälldin J., Fernaeus S., Pettersson C., and Land T. NADPH oxidase inhibitor diphenyliodonium abolishes lipopolysaccharide-induced down-regulation of transferring receptor expression in N2a and BV-2 cells. Journal of Neuroscience Research 84 (2006) 1047-1052
35. Richardson D.R., Kalinowski D.S., Jansson P.J., and Lovejoy D.B. Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents. Biochimica et Biophysica Acta (2008) 10.1016/jbbagen.2008.04.003
36. Roperto S., Ambrosio V., Borzacchiello G., Galati P., Russo V., et al. Bovine papillomavirus type-2 (BPV-2) infection and expression of uroplakin IIIb, a novel urothelial cell marker, in urinary bladder tumours of cows. Veterinary Pathology 42 (2005) 812-818
37. Roperto S., Borzacchiello G., Casellato R., Galati P., Russo V., et al. Sialic acid and GM3 ganglioside expression in papillomavirus-associated urinary bladder tumours of cattle with chronic enzootic haematuria. Journal of Comparative Pathology 132 (2007) 87-93
38. Roperto S., Brun R., Paolini F., Urraro C., Russo V., et al. Detection of bovine papillomavirus type 2 (BPV-2) in the peripheral blood of cattle with urinary bladder tumours: possible biological role. Journal of General Virology 89 (2008) 3027-3033
39. Ryder E.F., and Robakiewicz P. Statistics for the molecular biologist: group comparisons. Current Protocols in Molecular Biology A. 3I Suppl. 67 (1998) 1-22
40. Sammarco M.C., Ditch S., Banerjee A., and Grabczyk E. Ferritin L and H subunits are differentially regulated on a post-transcriptional level. Journal of Biological Chemistry 283 (2008) 4578-4587
41. Sauter G., Algaba F., Amin M.B., Busch C., Cheville J., et al. Non-invasive urothelial tumours. In: Eble J.N., Sauter G., Epstein J.I., and Sesterhenn I.A. (Eds). Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs (2004), IARC Press, Lyon 110-112
42. Thompson K.J., Fried M.G., Ye Z., Boyer P., and Connor R.J. Regulation, mechanisms and proposed function of ferritin translocation to cell nuclei. Journal of Cell Science 115 (2002) 2165-2177
43. Torti F.M., and Torti S.V. Regulation of ferritin genes and protein. Blood 99 (2002) 3505-3516
44. Tsirimonaki E., Ullah R., Marchetti B., Ashrafi G.H., McGarry L., et al. Similarities and differences between the E5 oncoproteins of bovine papillomaviruses type 1 and type 4: cytoskeleton, motility and invasiveness in E5-transformed bovine and mouse cells. Virus Research 115 (2006) 158-168
45. Tsuji Y. JunD activates transcription of the human ferritin H gene through an antioxidant response element during oxidative stress. Oncogene 24 (2005) 7567-7578
46. Vet J.A.M., van Moorselaar R.J.A., Debruyne F.M.J., and Schalken J.A. Differential expression of ferritin heavy chain in a rat transitional carcinoma progression model. Biochimica et Biophysica Acta 1360 (1997) 39-44
47. Zandman-Goddard G., and Shoenfeld Y. Ferritin in autoimmune diseases. Autoimmunity Reviews 6 (2007) 457-463