Activation of the liver X receptor prevents lipopolysaccharide-induced lung injury

Journal of Biological Chemistry

Volumn 284, Issue 44, 2009, Pages 30113-30121

  Gong, Haibiao ^a,c   He, Jinhan ^a   Lee, Jung Hoon ^a   Mallick, Edward ^b   Gao, Xiang ^a   Li, Song ^a   Homanics, Gregg E ^b   Xie, Wen ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c LI COR BIOSCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT ENZYME; GENES ENCODING; HEPATIC FUNCTION; HUMAN LUNG CANCER CELLS; IN-VIVO; ISOFORMS; LIPID HOMEOSTASIS; LIPOPOLYSACCHARIDES; LIVER X RECEPTORS; LUNG INJURY; MOUSE LUNG; PATHOPHYSIOLOGICAL; PULMONARY FUNCTION; REACTIVE OXYGEN SPECIES; STEROL SENSORS; TYPE II; WILD TYPES;

CATALYSTS; CELLS; LIVER; OXYGEN; POLYSACCHARIDES;

ENZYMES;

ANTIOXIDANT; LIPOPOLYSACCHARIDE; LIVER X RECEPTOR; LIVER X RECEPTOR AGONIST; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; MESSENGER RNA; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CONTROLLED STUDY; DNA BINDING; EPITHELIUM CELL; GOLGI COMPLEX; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG CANCER; LUNG FUNCTION; LUNG FUNCTION TEST; LUNG INJURY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ANIMALS; EPITHELIAL CELLS; GENE EXPRESSION; HUMANS; LIPOPOLYSACCHARIDES; LUNG; LUNG INJURY; LUNG NEOPLASMS; MICE; ORPHAN NUCLEAR RECEPTORS; OXIDOREDUCTASES;

MUS;

EID: 71049178598     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.047753     Document Type: Article

References (54)

1. Chow, C. W., Herrera Abreu, M. T., Suzuki, T., and Downey, G. P. (2003) Am. J. Respir. Cell Mol. Biol. 29, 427-431
2. Rahman, I., Biswas, S. K., Jimenez, L. A., Torres, M., and Forman, H. J. (2005) Antioxid. Redox Signal. 7, 42-59
3. Toyokuni, S., Okamoto, K., Yodoi, J., and Hiai, H. (1995) FEBS Lett. 358, 1-3
4. Nakamura, T., Nakamura, H., Hoshino, T., Ueda, S., Wada, H., and Yodoi, J. (2005) Antioxid. Redox Signal. 7, 60-71
5. Christofidou-Solomidou, M., and Muzykantov, V. R. (2006) Treat Respir. Med. 5, 47-78
6. Rahman, I. (2008) Ther. Adv. Respir. Dis. 2, 351-374
7. Mastruzzo, C., Crimi, N., and Vancheri, C. (2002) Monaldi. Arch. Chest Dis. 57, 173-176
8. Cho, H. Y., Reddy, S. P., and Kleeberger, S. R. (2006) Antioxid. Redox Signal. 8, 76-87
9. Wesselkamper, S. C., McDowell, S. A., Medvedovic, M., Dalton, T. P., Deshmukh, H. S., Sartor, M. A., Case, L. M., Henning, L. N., Borchers, M. T., Tomlinson, C. R., Prows, D. R., and Leikauf, G. D. (2006) Am. J. Respir. Cell Mol. Biol. 34, 73-82
10. Hayes, J. D., and Pulford, D. J. (1995) Crit. Rev. Biochem. Mol. Biol. 30, 445-600
11. Repa, J. J., and Mangelsdorf, D. J. (2002) Nat. Med. 8, 1243-1248
12. Willy, P. J., Umesono, K., Ong, E. S., Evans, R. M., Heyman, R. A., and Mangelsdorf, D. J. (1995) Genes Dev. 9, 1033-1045
13. Gong, H., and Xie, W. (2004) Expert Opin. Ther. Targets 8, 49-54
14. Uppal, H., Saini, S. P., Moschetta, A., Mu, Y., Zhou, J., Gong, H., Zhai, Y., Ren, S., Michalopoulos, G. K., Mangelsdorf, D. J., and Xie, W. (2007) Hepatology 45, 422-432
15. Zhou, J., Febbraio, M., Wada, T., Zhai, Y., Kuruba, R., He, J., Lee, J. H., Khadem, S., Ren, S., Li, S., Silverstein, R. L., and Xie, W. (2008) Gastroenterology 134, 556-567
16. Cummins, C. L., Volle, D. H., Zhang, Y., McDonald, J. G., Sion, B., Lefrançois-Martinez, A. M., Caira, F., Veyssière, G., Mangelsdorf, D. J., and Lobaccaro, J. M. (2006) J. Clin. Invest. 116, 1902-1912
17. Kalaany, N. Y., Gauthier, K. C., Zavacki, A. M., Mammen, P. P., Kitazume, T., Peterson, J. A., Horton, J. D., Garry, D. J., Bianco, A. C., and Mangelsdorf, D. J. (2005) Cell Metab. 1, 231-244
18. Laffitte, B. A., Chao, L. C., Li, J., Walczak, R., Hummasti, S., Joseph, S. B., Castrillo, A., Wilpitz, D. C., Mangelsdorf, D. J., Collins, J. L., Saez, E., and Tontonoz, P. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 5419-5424
19. Repa, J. J., Liang, G., Ou, J., Bashmakov, Y., Lobaccaro, J. M., Shimomura, I., Shan, B., Brown, M. S., Goldstein, J. L., and Mangelsdorf, D. J. (2000) Genes Dev. 14, 2819-2830
20. Tangirala, R. K., Bischoff, E. D., Joseph, S. B., Wagner, B. L., Walczak, R., Laffitte, B. A., Daige, C. L., Thomas, D., Heyman, R. A., Mangelsdorf, D. J., Wang, X., Lusis, A. J., Tontonoz, P., and Schulman, I. G. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 11896-11901
21. Venkateswaran, A., Laffitte, B. A., Joseph, S. B., Mak, P. A., Wilpitz, D. C., Edwards, P. A., and Tontonoz, P. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 12097-12102
22. Joseph, S. B., Castrillo, A., Laffitte, B. A., Mangelsdorf, D. J., and Tontonoz, P. (2003) Nat. Med. 9, 213-219
23. Joseph, S. B., Bradley, M. N., Castrillo, A., Bruhn, K. W., Mak, P. A., Pei, L., Hogenesch, J., O'connell, R. M., Cheng, G., Saez, E., Miller, J. F., and Tontonoz, P. (2004) Cell 119, 299-309
24. Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W., and Roder, J. C. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 8424-8428
25. Homanics, G. E., Ferguson, C., Quinlan, J. J., Daggett, J., Snyder, K., Lagenaur, C., Mi, Z. P., Wang, X. H., Grayson, D. R., and Firestone, L. L. (1997) Mol. Pharmacol. 51, 588-596
26. Szarka, R. J., Wang, N., Gordon, L., Nation, P. N., and Smith, R. H. (1997) J. Immunol. Methods 202, 49-57
27. Ritter, C., Andrades, M. E., Reinke, A., Menna-Barreto, S., Moreira, J. C., and Dal-Pizzol, F. (2004) Crit. Care Med. 32, 342-349
28. Bradley, P. P., Priebat, D. A., Christensen, R. D., and Rothstein, G. (1982) J. Invest. Dermatol. 78, 206-209
29. Gong, H., Singh, S. V., Singh, S. P., Mu, Y., Lee, J. H., Saini, S. P., Toma, D., Ren, S., Kagan, V. E., Day, B. W., Zimniak, P., and Xie, W. (2006) Mol. Endocrinol. 20, 279-290
30. Paoletti, F., and Mocali, A. (1990) Methods Enzymol. 186, 209-220
31. Aebi, H. (1984) Methods Enzymol. 105, 121-126
32. Bligh, E. G., and Dyer, W. J. (1959) Can. J. Biochem. Physiol. 37, 911-917
33. Rouser, G., Fkeischer, S., and Yamamoto, A. (1970) Lipids 5, 494-496
34. Zhou, J., Zhai, Y., Mu, Y., Gong, H., Uppal, H., Toma, D., Ren, S., Evans, R. M., and Xie, W. (2006) J. Biol. Chem. 281, 15013-15020
35. Voorhout, W. F., Veenendaal, T., Haagsman, H. P., Weaver, T. E., Whitsett, J. A., van Golde, L. M., and Geuze, H. J. (1992) Am. J. Physiol. 263, L479-L486
36. Jia, L., Xu, M., Zhen, W., Shen, X., Zhu, Y., Wang, W., and Wang, X. (2008) Am. J. Physiol. Cell Physiol. 294, C47-C55
37. Jenkins, J. K., Carey, P. D., Byrne, K., Sugerman, H. J., and Fowler, A. A., 3rd (1991) Am. Rev. Respir. Dis. 143, 155-161
38. Been, J. V., and Zimmermann, L. J. (2007) Eur. J. Pediatr. 166, 889-899
39. Willson, D. F., Chess, P. R., and Notter, R. H. (2008) Pediatr. Clin. North Am. 55, 545-575
40. Kennedy, M. A., Venkateswaran, A., Tarr, P. T., Xenarios, I., Kudoh, J., Shimizu, N., and Edwards, P. A. (2001) J. Biol. Chem. 276, 39438-39447
41. Guo, R. F., and Ward, P. A. (2007) Antioxid. Redox Signal. 9, 1991-2002
42. Lang, J. D., McArdle, P. J., O'Reilly, P. J., and Matalon, S. (2002) Chest 122, 314S-320S
43. Matsukawa, A., Hogaboam, C. M., Lukacs, N. W., Lincoln, P. M., Strieter, R. M., and Kunkel, S. L. (1999) J. Immunol. 163, 6148-6154
44. Wells, C. A., Ravasi, T., Faulkner, G. J., Carninci, P., Okazaki, Y., Hayashizaki, Y., Sweet, M., Wainwright, B. J., and Hume, D. A. (2003) BMC Immunol. 4, 5
45. Castrillo, A., Joseph, S. B., Marathe, C., Mangelsdorf, D. J., and Tontonoz, P. (2003) J. Biol. Chem. 278, 10443-10449
46. Castrillo, A., Joseph, S. B., Vaidya, S. A., Haberland, M., Fogelman, A. M., Cheng, G., and Tontonoz, P. (2003) Mol. Cell 12, 805-816
47. Birrell, M. A., Catley, M. C., Hardaker, E., Wong, S., Willson, T. M., McCluskie, K., Leonard, T., Farrow, S. N., Collins, J. L., Haj-Yahia, S., and Belvisi, M. G. (2007) J. Biol. Chem. 282, 31882-31890
48. Reddy, R. C., Keshamouni, V. G., Jaigirdar, S. H., Zeng, X., Leff, T., Thannickal, V. J., and Standiford, T. J. (2004) Am. J. Physiol. Lung Cell Mol. Physiol. 286, L613-L619
49. Asada, K., Sasaki, S., Suda, T., Chida, K., and Nakamura, H. (2004) Am. J. Respir. Crit. Care Med. 169, 195-200
50. Christensen, P. J., Goodman, R. E., Pastoriza, L., Moore, B., and Toews, G. B. (1999) Am. J. Pathol. 155, 1773-1779
51. Park, E. Y., Cho, I. J., and Kim, S. G. (2004) Cancer Res. 64, 3701-3713
52. Bookout, A. L., Jeong, Y., Downes, M., Yu, R. T., Evans, R. M., and Mangelsdorf, D. J. (2006) Cell 126, 789-799
53. Akiyama, T. E., Sakai, S., Lambert, G., Nicol, C. J., Matsusue, K., Pimprale, S., Lee, Y. H., Ricote, M., Glass, C. K., Brewer, H. B., Jr., and Gonzalez, F. J. (2002) Mol. Cell. Biol. 22, 2607-2619
54. Albers, M., Blume, B., Schlueter, T., Wright, M. B., Kober, I., Kremoser, C., Deuschle, U., and Koegl, M. (2006) J. Biol. Chem. 281, 4920-4930