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Volumn 10, Issue , 2009, Pages

An empirical Bayesian approach for model-based inference of cellular signaling networks

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE MARKOV CHAIN MONTE CARLO; CELLULAR SIGNALING NETWORKS; COMPLICATED STRUCTURES; CONVERGENCE CRITERION; EPIDERMAL GROWTH FACTORS; POSTERIOR DISTRIBUTIONS; PRIMARY RAT HEPATOCYTES; SIGNAL TRANSDUCTION MECHANISM;

EID: 71049127915     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-10-371     Document Type: Article
Times cited : (54)

References (57)
  • 2
    • 0036729047 scopus 로고    scopus 로고
    • Can a biologist fix a radio?--Or, what I learned while studying apoptosis
    • 10.1016/S1535-6108(02)00133-2, 12242150
    • Lazebnik Y. Can a biologist fix a radio?--Or, what I learned while studying apoptosis. Cancer Cell 2002, 2:179-183. 10.1016/S1535-6108(02)00133-2, 12242150.
    • (2002) Cancer Cell , vol.2 , pp. 179-183
    • Lazebnik, Y.1
  • 3
    • 39749086288 scopus 로고    scopus 로고
    • Integrative mathematical oncology
    • 10.1038/nrc2329, 18273038
    • Anderson AR, Quaranta V. Integrative mathematical oncology. Nat Rev Cancer 2008, 8(3):227-234. 10.1038/nrc2329, 18273038.
    • (2008) Nat Rev Cancer , vol.8 , Issue.3 , pp. 227-234
    • Anderson, A.R.1    Quaranta, V.2
  • 4
    • 84890058821 scopus 로고    scopus 로고
    • Signaling Networks and Mathematics
    • 10.1126/scisignal.143eg7, 18957689
    • Yaffe MB. Signaling Networks and Mathematics. Sci Signal 2008, 1:eg7. 10.1126/scisignal.143eg7, 18957689.
    • (2008) Sci Signal , vol.1
    • Yaffe, M.B.1
  • 5
    • 24944499257 scopus 로고    scopus 로고
    • Lexicography of kinetic modeling of complex reaction networks
    • Broadbelt LJ, Pfaendtner J. Lexicography of kinetic modeling of complex reaction networks. AIChE J 2005, 51:2112-2121.
    • (2005) AIChE J , vol.51 , pp. 2112-2121
    • Broadbelt, L.J.1    Pfaendtner, J.2
  • 6
    • 0004134359 scopus 로고    scopus 로고
    • Washington, DC: National Academies Press
    • National Research Council (US) Committee on Learning, Research, Practice and Education How people learn: brain, mind, experience, and school 2000, Washington, DC: National Academies Press.
    • (2000) How people learn: brain, mind, experience, and school
  • 7
    • 46349105936 scopus 로고    scopus 로고
    • Optimization in computational systems biology
    • Banga JR. Optimization in computational systems biology. BMC Sys Bio 2008, 2:47.
    • (2008) BMC Sys Bio , vol.2 , pp. 47
    • Banga, J.R.1
  • 10
    • 34250658998 scopus 로고    scopus 로고
    • Bayesian methods in bioinformatics and computational systems biology
    • 10.1093/bib/bbm007, 17430978
    • Wilkinson DJ. Bayesian methods in bioinformatics and computational systems biology. Briefings in Bioinformatics 2007, 8(2):109-116. 10.1093/bib/bbm007, 17430978.
    • (2007) Briefings in Bioinformatics , vol.8 , Issue.2 , pp. 109-116
    • Wilkinson, D.J.1
  • 11
    • 32444440370 scopus 로고    scopus 로고
    • Bayesian parameter estimation with informative priors for nonlinear systems
    • Coleman MC, Block DE. Bayesian parameter estimation with informative priors for nonlinear systems. AIChE J 2006, 52(2):651-667.
    • (2006) AIChE J , vol.52 , Issue.2 , pp. 651-667
    • Coleman, M.C.1    Block, D.E.2
  • 12
    • 40749094910 scopus 로고    scopus 로고
    • Bayesian ranking of biochemical system models
    • 10.1093/bioinformatics/btm607, 18057018
    • Vyshemirsky V, Girolami MA. Bayesian ranking of biochemical system models. Bioinformatics 2008, 24(6):833-839. 10.1093/bioinformatics/btm607, 18057018.
    • (2008) Bioinformatics , vol.24 , Issue.6 , pp. 833-839
    • Vyshemirsky, V.1    Girolami, M.A.2
  • 13
    • 34249856850 scopus 로고    scopus 로고
    • Bayesian model-based inference of transcription factor activity
    • 1892071, 17493251, 10.1186/1471-2105-8-S2-S2
    • Rogers S, Khanin R, Girolami M. Bayesian model-based inference of transcription factor activity. BMC Bioinformatics 2007, 8(Suppl 2):S2. 1892071, 17493251, 10.1186/1471-2105-8-S2-S2.
    • (2007) BMC Bioinformatics , vol.8 , Issue.SUPPL 2
    • Rogers, S.1    Khanin, R.2    Girolami, M.3
  • 14
    • 0037168597 scopus 로고    scopus 로고
    • An ensemble method for identifying regulatory circuits with special reference to the qa gene cluster of Neurospora crassa
    • 139242, 12477937, 10.1073/pnas.262658899
    • Battogtokh D, Asch DK, Case ME, Arnold J, Schuttler HB. An ensemble method for identifying regulatory circuits with special reference to the qa gene cluster of Neurospora crassa. Proc Natl Acad Sci USA 2002, 99(26):16904-16909. 139242, 12477937, 10.1073/pnas.262658899.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.26 , pp. 16904-16909
    • Battogtokh, D.1    Asch, D.K.2    Case, M.E.3    Arnold, J.4    Schuttler, H.B.5
  • 15
    • 42749109054 scopus 로고    scopus 로고
    • Statistical mechanical approaches to models with many poorly known parameters
    • Brown KS, Sethna JP. Statistical mechanical approaches to models with many poorly known parameters. Phys Rev E 2003, 68(2):021904.
    • (2003) Phys Rev E , vol.68 , Issue.2 , pp. 021904
    • Brown, K.S.1    Sethna, J.P.2
  • 16
    • 58149142997 scopus 로고    scopus 로고
    • Approximate Bayesian computation scheme for parameter inference and model selection in dynamical systems
    • Toni T, Welch D, Strelkowa N, Ipsen A, Stumpf MPH. Approximate Bayesian computation scheme for parameter inference and model selection in dynamical systems. Journal of the Royal Society Interface 2009, 6(31):187-202.
    • (2009) Journal of the Royal Society Interface , vol.6 , Issue.31 , pp. 187-202
    • Toni, T.1    Welch, D.2    Strelkowa, N.3    Ipsen, A.4    Stumpf, M.P.H.5
  • 17
  • 18
    • 0033570090 scopus 로고    scopus 로고
    • Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor
    • 10.1074/jbc.274.42.30169, 10514507
    • Kholodenko BN, Demin OV, Moehren G, Hoek JB. Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor. J Biol Chem 1999, 274:30169-30181. 10.1074/jbc.274.42.30169, 10514507.
    • (1999) J Biol Chem , vol.274 , pp. 30169-30181
    • Kholodenko, B.N.1    Demin, O.V.2    Moehren, G.3    Hoek, J.B.4
  • 19
    • 0036212767 scopus 로고    scopus 로고
    • Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors
    • 10.1038/nbt0402-370, 11923843
    • Schoeberl B, Eichler-Jonsson C, Gilles ED, Muller G. Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors. Nat Biotechnol 2002, 20(4):370-375. 10.1038/nbt0402-370, 11923843.
    • (2002) Nat Biotechnol , vol.20 , Issue.4 , pp. 370-375
    • Schoeberl, B.1    Eichler-Jonsson, C.2    Gilles, E.D.3    Muller, G.4
  • 20
    • 0041843750 scopus 로고    scopus 로고
    • An Integrated Model of Epidermal Growth Factor Receptor Trafficking and Signal Transduction
    • 1303198, 12885624, 10.1016/S0006-3495(03)74516-0
    • Resat H, Ewald JA, Dixon DA, Wiley HS. An Integrated Model of Epidermal Growth Factor Receptor Trafficking and Signal Transduction. Biophys J 2003, 85:730-743. 1303198, 12885624, 10.1016/S0006-3495(03)74516-0.
    • (2003) Biophys J , vol.85 , pp. 730-743
    • Resat, H.1    Ewald, J.A.2    Dixon, D.A.3    Wiley, H.S.4
  • 21
    • 32044469862 scopus 로고    scopus 로고
    • A Network Model of Early Events in Epidermal Growth Factor Receptor Signaling That Accounts for Combinatorial Complexity
    • 10.1016/j.biosystems.2005.06.014, 16233948
    • Blinov ML, Faeder JR, Goldstein B, Hlavacek WS. A Network Model of Early Events in Epidermal Growth Factor Receptor Signaling That Accounts for Combinatorial Complexity. Biosystems 2006, 83:136-151. 10.1016/j.biosystems.2005.06.014, 16233948.
    • (2006) Biosystems , vol.83 , pp. 136-151
    • Blinov, M.L.1    Faeder, J.R.2    Goldstein, B.3    Hlavacek, W.S.4
  • 22
    • 36248988538 scopus 로고    scopus 로고
    • Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses
    • Birtwistle MR, Hatakeyama M, Yumoto N, Ogunnaike BA, Hoek JB, Kholodenko BN. Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses. Mol Sys Bio 2007, 3:144., http://www.biomedcentral.com/pubmed/18004277
    • (2007) Mol Sys Bio , vol.3 , pp. 144
    • Birtwistle, M.R.1    Hatakeyama, M.2    Yumoto, N.3    Ogunnaike, B.A.4    Hoek, J.B.5    Kholodenko, B.N.6
  • 23
    • 0037453510 scopus 로고    scopus 로고
    • Assembly of Cell Regulatory Systems Through Protein Interaction Domains
    • 10.1126/science.1083653, 12702867
    • Pawson T, Nash P. Assembly of Cell Regulatory Systems Through Protein Interaction Domains. Science 2003, 300:445-452. 10.1126/science.1083653, 12702867.
    • (2003) Science , vol.300 , pp. 445-452
    • Pawson, T.1    Nash, P.2
  • 24
    • 0031190827 scopus 로고    scopus 로고
    • Mechanism Reduction during Computer Generation of Compact Reaction Models
    • Klinke DJ, Broadbelt LJ. Mechanism Reduction during Computer Generation of Compact Reaction Models. AIChE J 1997, 43:1828-1837.
    • (1997) AIChE J , vol.43 , pp. 1828-1837
    • Klinke, D.J.1    Broadbelt, L.J.2
  • 25
    • 0033167178 scopus 로고    scopus 로고
    • Construction of a Mechanistic Model of Fischer-Tropsch Synthesis on Ni(111) and Co(0001) Surfaces
    • Klinke DJ, Broadbelt LJ. Construction of a Mechanistic Model of Fischer-Tropsch Synthesis on Ni(111) and Co(0001) Surfaces. Chem Eng Sci 1999, 54:3379-3389.
    • (1999) Chem Eng Sci , vol.54 , pp. 3379-3389
    • Klinke, D.J.1    Broadbelt, L.J.2
  • 27
    • 30544449081 scopus 로고    scopus 로고
    • A quantitative protein interaction network for the ErbB receptors using protein microarrays
    • 10.1038/nature04177, 16273093
    • Jones RB, Gordus A, Krall JA, MacBeath G. A quantitative protein interaction network for the ErbB receptors using protein microarrays. Nature 2006, 439:168-174. 10.1038/nature04177, 16273093.
    • (2006) Nature , vol.439 , pp. 168-174
    • Jones, R.B.1    Gordus, A.2    Krall, J.A.3    MacBeath, G.4
  • 28
    • 43949125837 scopus 로고    scopus 로고
    • A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R
    • 10.1039/b801018h, 18493663
    • Kaushansky A, Gordus A, Chang B, Rush J, MacBeath G. A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R. Molecular Biosystems 2008, 4(6):643-653. 10.1039/b801018h, 18493663.
    • (2008) Molecular Biosystems , vol.4 , Issue.6 , pp. 643-653
    • Kaushansky, A.1    Gordus, A.2    Chang, B.3    Rush, J.4    MacBeath, G.5
  • 29
    • 44849085131 scopus 로고    scopus 로고
    • Modulating Temporal Control of NF-kappaB Activation: Implications for Therapeutic and Assay Selection
    • 2480691, 18281385, 10.1529/biophysj.107.120451
    • Klinke DJ, Ustyugova IV, Brundage K, Barnett JB. Modulating Temporal Control of NF-kappaB Activation: Implications for Therapeutic and Assay Selection. Biophys J 2008, 94(11):4249-4259. 2480691, 18281385, 10.1529/biophysj.107.120451.
    • (2008) Biophys J , vol.94 , Issue.11 , pp. 4249-4259
    • Klinke, D.J.1    Ustyugova, I.V.2    Brundage, K.3    Barnett, J.B.4
  • 31
    • 0037039289 scopus 로고    scopus 로고
    • Temperature dependence of the epidermal growth factor receptor signaling network can be accounted for by a kinetic model
    • 10.1021/bi011506c, 11772030
    • Moehren G, Markevich N, Demin O, Kiyatkin A, Goryanin I, Hoek JB, Kholodenko BN. Temperature dependence of the epidermal growth factor receptor signaling network can be accounted for by a kinetic model. Biochemistry 2002, 41:306-320. 10.1021/bi011506c, 11772030.
    • (2002) Biochemistry , vol.41 , pp. 306-320
    • Moehren, G.1    Markevich, N.2    Demin, O.3    Kiyatkin, A.4    Goryanin, I.5    Hoek, J.B.6    Kholodenko, B.N.7
  • 33
    • 0000863827 scopus 로고
    • The Bayesian Estimation of Common Parameters from Several Responses
    • 10.1093/biomet/52.3-4.355
    • Box GEP, Draper NR. The Bayesian Estimation of Common Parameters from Several Responses. Biometrika 1965, 52:355-365. 10.1093/biomet/52.3-4.355.
    • (1965) Biometrika , vol.52 , pp. 355-365
    • Box, G.E.P.1    Draper, N.R.2
  • 35
    • 77956890234 scopus 로고
    • Monte Carlo sampling methods using Markov chains and their applications
    • Hastings WK. Monte Carlo sampling methods using Markov chains and their applications. Biometrika 1970, 57:97-109.
    • (1970) Biometrika , vol.57 , pp. 97-109
    • Hastings, W.K.1
  • 36
    • 0000954353 scopus 로고    scopus 로고
    • Efficient Metropolis Jumping Rules
    • Oxford University Press, Bernardo BJODAPJM, Smith AFM
    • Gelman A, Roberts GO, Gilks WR. Efficient Metropolis Jumping Rules. Bayesian Statistics 5 1996, 599-607. Oxford University Press, Bernardo BJODAPJM, Smith AFM.
    • (1996) Bayesian Statistics 5 , pp. 599-607
    • Gelman, A.1    Roberts, G.O.2    Gilks, W.R.3
  • 37
    • 34548026526 scopus 로고    scopus 로고
    • Coupling and ergodicity of adaptive Markov chain Monte Carlo algorithms
    • Roberts GO, Rosenthal JS. Coupling and ergodicity of adaptive Markov chain Monte Carlo algorithms. J Appl Prob 2007, 44(2):458-475.
    • (2007) J Appl Prob , vol.44 , Issue.2 , pp. 458-475
    • Roberts, G.O.1    Rosenthal, J.S.2
  • 38
    • 0030539336 scopus 로고    scopus 로고
    • Markov chain Monte Carlo convergence diagnostics: A comparative review
    • Cowles MK, Carlin BP. Markov chain Monte Carlo convergence diagnostics: A comparative review. J Am Stat Assoc 1996, 91(434):883-904.
    • (1996) J Am Stat Assoc , vol.91 , Issue.434 , pp. 883-904
    • Cowles, M.K.1    Carlin, B.P.2
  • 39
    • 71049117627 scopus 로고    scopus 로고
    • Simplification of chemical reaction systems by time-scale analysis
    • Okino MS, Mavrovouniotis ML. Simplification of chemical reaction systems by time-scale analysis. Chem Eng Comm 1999, 176:115-131.
    • (1999) Chem Eng Comm , vol.176 , pp. 115-131
    • Okino, M.S.1    Mavrovouniotis, M.L.2
  • 41
    • 84972492387 scopus 로고
    • Inference from Iterative Simulation Using Multiple Sequences
    • Gelman A, Rubin DB. Inference from Iterative Simulation Using Multiple Sequences. Stat Sci 1992, 7(4):457-472.
    • (1992) Stat Sci , vol.7 , Issue.4 , pp. 457-472
    • Gelman, A.1    Rubin, D.B.2
  • 42
    • 0032273615 scopus 로고    scopus 로고
    • General methods for monitoring convergence of iterative simulations
    • Brooks SP, Gelman A. General methods for monitoring convergence of iterative simulations. J Comp Graph Stat 1998, 7(4):434-455.
    • (1998) J Comp Graph Stat , vol.7 , Issue.4 , pp. 434-455
    • Brooks, S.P.1    Gelman, A.2
  • 44
    • 33750374139 scopus 로고    scopus 로고
    • Linking data to models: data regression
    • Jaqaman K, Danuser G. Linking data to models: data regression. Nature Rev Mol Cell Bio 2006, 7:813-819.
    • (2006) Nature Rev Mol Cell Bio , vol.7 , pp. 813-819
    • Jaqaman, K.1    Danuser, G.2
  • 45
    • 0035964187 scopus 로고    scopus 로고
    • Real-time kinetics of ligand/cell surface receptor interactions in living cells: Binding of epidermal growth factor to the epidermal growth factor receptor
    • 10.1021/bi010705t, 11513601
    • Wilkinson JC, Stein RA, Guyer CA, Beechem JM, Staros JV. Real-time kinetics of ligand/cell surface receptor interactions in living cells: Binding of epidermal growth factor to the epidermal growth factor receptor. Biochemistry 2001, 40(34):10230-10242. 10.1021/bi010705t, 11513601.
    • (2001) Biochemistry , vol.40 , Issue.34 , pp. 10230-10242
    • Wilkinson, J.C.1    Stein, R.A.2    Guyer, C.A.3    Beechem, J.M.4    Staros, J.V.5
  • 46
    • 38349190632 scopus 로고    scopus 로고
    • Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system
    • 2224169, 18165319, 10.1073/pnas.0707080105
    • Macdonald JL, Pike LJ. Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system. Proc Natl Acad Sci USA 2008, 105:112-117. 2224169, 18165319, 10.1073/pnas.0707080105.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 112-117
    • Macdonald, J.L.1    Pike, L.J.2
  • 47
    • 58549083142 scopus 로고    scopus 로고
    • Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data
    • Chen WW, Schoeberl B, Jasper PJ, Niepel M, Nielsen UB, Lauffenburger DA, Sorger PK. Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data. Mol Sys Bio 2009, 5:239., http://www.biomedcentral.com/pubmed/19156131
    • (2009) Mol Sys Bio , vol.5 , pp. 239
    • Chen, W.W.1    Schoeberl, B.2    Jasper, P.J.3    Niepel, M.4    Nielsen, U.B.5    Lauffenburger, D.A.6    Sorger, P.K.7
  • 48
    • 33644508366 scopus 로고    scopus 로고
    • Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
    • 1383569, 16467847, 10.1038/sj.emboj.7600991
    • Husebye H, Halaas O, Stenmark H, Tunheim G, Sandanger O, Bogen B, Brech A, Latz E, Espevik T. Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. Embo Journal 2006, 25(4):683-692. 1383569, 16467847, 10.1038/sj.emboj.7600991.
    • (2006) Embo Journal , vol.25 , Issue.4 , pp. 683-692
    • Husebye, H.1    Halaas, O.2    Stenmark, H.3    Tunheim, G.4    Sandanger, O.5    Bogen, B.6    Brech, A.7    Latz, E.8    Espevik, T.9
  • 49
    • 48649086002 scopus 로고    scopus 로고
    • Separate endocytic pathways regulate IL-5 receptor internalization and signaling
    • 2493073, 18511572, 10.1189/jlb.1207828
    • Lei JT, Martinez-Moczygemba M. Separate endocytic pathways regulate IL-5 receptor internalization and signaling. Journal of Leukocyte Biology 2008, 84(2):499-509. 2493073, 18511572, 10.1189/jlb.1207828.
    • (2008) Journal of Leukocyte Biology , vol.84 , Issue.2 , pp. 499-509
    • Lei, J.T.1    Martinez-Moczygemba, M.2
  • 50
    • 47749089820 scopus 로고    scopus 로고
    • Regulation of TNFR1 and CD95 signalling by receptor compartmentalization
    • 10.1038/nrm2430, 18545270
    • Schutze S, Tchikov V, Schneider-Brachert W. Regulation of TNFR1 and CD95 signalling by receptor compartmentalization. Nature Reviews Molecular Cell Biology 2008, 9(8):655-662. 10.1038/nrm2430, 18545270.
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.8 , pp. 655-662
    • Schutze, S.1    Tchikov, V.2    Schneider-Brachert, W.3
  • 51
    • 0030461226 scopus 로고    scopus 로고
    • Control of EGF receptor signaling by clathrin-mediated endocytosis
    • 10.1126/science.274.5295.2086, 8953040
    • Vieira AV, Lamaze C, Schmid SL. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 1996, 274(5295):2086-2089. 10.1126/science.274.5295.2086, 8953040.
    • (1996) Science , vol.274 , Issue.5295 , pp. 2086-2089
    • Vieira, A.V.1    Lamaze, C.2    Schmid, S.L.3
  • 52
    • 0016355478 scopus 로고
    • A New Look at the Statistical Model Identification
    • Akaike H. A New Look at the Statistical Model Identification. IEEE Trans Automat Control 1974, 19:716-723.
    • (1974) IEEE Trans Automat Control , vol.19 , pp. 716-723
    • Akaike, H.1
  • 53
    • 0018091195 scopus 로고
    • Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations
    • 10.1007/BF01117450, 671222
    • Yamaoka K, Nakagawa T, Uno T. Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations. J Pharmacokinet Biopharm 1978, 6:165-175. 10.1007/BF01117450, 671222.
    • (1978) J Pharmacokinet Biopharm , vol.6 , pp. 165-175
    • Yamaoka, K.1    Nakagawa, T.2    Uno, T.3
  • 54
    • 0023113597 scopus 로고
    • Statistical methods for model discrimination. Applications to gating kinetics and permeation of the acetylcholine receptor channel
    • 1329886, 2435330, 10.1016/S0006-3495(87)83331-3
    • Horn R. Statistical methods for model discrimination. Applications to gating kinetics and permeation of the acetylcholine receptor channel. Biophys J 1987, 51:255-263. 1329886, 2435330, 10.1016/S0006-3495(87)83331-3.
    • (1987) Biophys J , vol.51 , pp. 255-263
    • Horn, R.1
  • 55
    • 0038048325 scopus 로고    scopus 로고
    • Inferring Genetic Networks and Identifying Compound Mode of Action via Expression Profiling
    • 10.1126/science.1081900, 12843395
    • Gardner TS, di Bernardo D, Lorenz D, Collins JJ. Inferring Genetic Networks and Identifying Compound Mode of Action via Expression Profiling. Science 2003, 301:102-105. 10.1126/science.1081900, 12843395.
    • (2003) Science , vol.301 , pp. 102-105
    • Gardner, T.S.1    di Bernardo, D.2    Lorenz, D.3    Collins, J.J.4
  • 56
    • 59049085394 scopus 로고    scopus 로고
    • A network biology approach to aging in yeast
    • 2629491, 19164565, 10.1073/pnas.0812551106
    • Lorenz DR, Cantor CR, Collins JJ. A network biology approach to aging in yeast. Proc Natl Acad Sci USA 2009, 106:1145-1150. 2629491, 19164565, 10.1073/pnas.0812551106.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 1145-1150
    • Lorenz, D.R.1    Cantor, C.R.2    Collins, J.J.3


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