GSH depletion, protein S-glutathionylation and mitochondrial transmembrane potential hyperpolarization are early events in initiation of cell death induced by a mixture of isothiazolinones in HL60 cells

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1763, Issue 2, 2006, Pages 214-225

  Di Stefano, Anna ^a   Frosali, Simona ^a   Leonini, Alessandra ^a   Ettorre, Anna ^a   Priora, Raffaella ^a   Di Simplicio, Francesca Cherubini ^a   Di Simplicio, Paolo ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

Apoptosis; Caspases; Glutathione; Mitochondrial transmembrane potential; Reactive oxygen species; S glutathionylation

Indexed keywords

2 METHYL 4 ISOTHIAZOLIN 3 ONE; 5 CHLORO 2 METHYL 4 ISOTHIAZOLIN 3 ONE; CASPASE 9; GLUTATHIONE; PROTEIN S; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DEATH; CELL STRAIN HL 60; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYPERPOLARIZATION; PRIORITY JOURNAL;

APOPTOSIS; CASPASE 9; CASPASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLOW CYTOMETRY; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HL-60 CELLS; HUMANS; KINETICS; MEMBRANE POTENTIALS; MITOCHONDRIA; NECROSIS; PRESERVATIVES, PHARMACEUTICAL; REACTIVE OXYGEN SPECIES; SPECTROPHOTOMETRY, ULTRAVIOLET; THIAZOLES;

EID: 33644976378     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2005.12.012     Document Type: Article

References (49)

1. C. Thompson Apoptosis in pathogenesis and treatment of disease Science 267 1995 1456 1461
2. M.O. Hengartner The biochemistry of apoptosis Nature 407 2000 770 776
3. J.D. Robertson, and S. Orrenius Molecular mechanisms of apoptosis induced by cytotoxic chemicals Crit. Rev. Toxicol. 30 2000 609 627
4. G. Majno, and I. Joris Apoptosis, oncosis, and necrosis. An overview of cell death Am. J. Pathol. 146 1995 3 15
5. G. Denecker, D. Vercammen, W. Declercq, and P. Vandenabeele Apoptotic and necrotic cell death induced by death domain receptors Cell. Mol. Life Sci. 58 2001 356 370
6. A.G. Renehan, C. Booth, and C.S. Potten What is apoptosis, and why is it important? BMJ 322 2001 1536 1538
7. J.F. Kerr, A.H. Wyllie, and A.R. Currie Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics Br. J. Cancer 26 1972 239 257
8. H.M. Ellis, J. Yuan, and H.R. Horvitz Mechanism and functions of cell death Annu. Rev. Cell. Biol. 7 1991 663 693
9. C. Anselmi, A. Ettorre, M. Andreassi, M. Centini, P. Neri, and A. Di Stefano In vitro induction of apoptosis vs..necrosis by widely used preservatives: 2-phenoxyethanol, a mixture of isothiazolinones, imidazolidinyl urea and 1,2-pentanediol Biochem. Pharmacol. 63 2002 437 453
10. J. Chandra, A. Samali, and S. Orrenius Triggering and modulation of apoptosis by oxidative stress Free Radic. Biol. Med. 29 2000 323 333
11. M.A. Davis, J.A. Flaws, M. Young, K. Collins, and N.H. Colburn Effect of ceramide on intracellular glutathione determines apoptotic or necrotic cell death of JB6 tumor cells Toxicol. Sci. 53 2000 48 55
12. A. Ettorre, A. Andreassi, C. Anselmi, P. Neri, L. Andreassi, and A. Di Stefano Involvement of oxidative stress in apoptosis induced by a mixture of isothiazolinones in normal human keratinocytes J. Invest. Dermatol. 121 2003 328 336
13. S. Du, B. McLaughlin, S. Pal, and E. Aizenman In vitro neurotoxicity of methylisothiazolinone, a commonly used industrial and household biocide, proceeds via a zinc and extracellular signal-regulated kinase mitogen-activated protein kinase-dependent pathway J. Neurosci. 22 2002 7408 7416
14. P.J. Collier, A. Ramsey, R.D. Waigh, K.T. Douglas, P. Austin, and P. Gilbert Chemical reactivity of some isothiazolone biocides J. Appl. Bacteriol. 69 1990 578 584
15. R. Alvarez-Sanchez, M. Divkovic, D. Basketter, C. Pease, M. Panico, A. Dell, H. Morris, and J.P. Lepoittevin Effect of glutathione on the covalent binding of the 13C-labeled skin sensitizer 5-chloro-2-methylisothiazol-3-one to human serum albumin: identification of adducts by nuclear magnetic resonance, matrix-assisted laser desorption/ionization mass spectrometry, and nanoelectrospray tandem mass spectrometry Chem. Res. Toxicol. 17 2004 1280 1288
16. B. Gruvemberg, and M. Bruze Can glutathione-containing emollients inactive methylchloroisothiazolinone/methylisothiazolinone Contact Dermatitis 38 1998 261 265
17. K. Xu, and P.J. Thornalley Involvement of glutathione metabolism in the cytotoxicity of the phenethyl isothiocyanate and its cysteine conjugate to human leukaemia cells in vitro Biochem. Pharmacol. 61 2001 165 177
18. M. Merad-Boudia, A. Nicole, D. Santiard-Baron, C. Saille, and I.M. Ceballos-Picot Mitochondria impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells. Relevance to Parkinson's disease Biochem. Pharmacol. 56 1998 645 655
19. R.S. Fernandes, and T. Cotter Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death Biochem. Pharmacol. 48 1994 675 681
20. D. Van de Dobbelsteen, S. Nobel, J. Schlegel, I.A. Cotgreave, S. Orrenius, and A.J. Slater Rapid and specific efflux of reduced glutathione during apoptosis induced by anti-Fas/APO-1 antibody J. Biol. Chem. 271 1996 15420 15427
21. L. Ghibelli, S. Coppola, C. Fanelli, G. Rotilio, P. Civitareale, A.I. Scovassi, and M.R. Ciriolo Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis FASEB J. 13 1999 2031 2036
22. C. Debbasch, P.J. Pisella, M. De Saint Jean, P. Rat, J.M. Warnet, and C. Baudouin Mitochondrial activity and glutathione injury in apoptosis induced by unpreserved and preserved β-blockers on Chang conjunctival cells Investig. Ophthalmol. Vis. Sci. 42 2001 2525 2533
23. F.X. Sureda, C. Gabriel, J. Comas, M. Pallàs, E. Escubedo, J. Camarasa, and A. Camins Evaluation of free radical production, mitochondrial membrane potential and cytoplasmic calcium in mammalian neurons by flow cytometry Brain Res. Protoc. 4 1999 280 287
24. J. Treumer, and G. Valet Flow-cytometric determination of glutathione alterations in vital cells by o-phthaldialdehyde (OPT) staining Exp. Cell Res. 163 1986 518 524
25. W. Gorczyca, M.R. Melamed, and Z. Darzynkiewicz Analysis of apoptosis by flow cytometry M.J. Jaroszeski R. Heller Flow Cytometry Protocols Methods in Molecular Biology vol. 91 1998 Umana Press Inc Totowa, NJ 217 238
26. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
27. M.A. Mansoor, A.M. Svardal, and P.M. Ueland Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma Anal. Biochem. 200 1992 218 229
28. G.E. Glock, and P. McLean Further studies on the properties and assay of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase of rat liver Biochem. J. 55 1953 400 408
29. I. Carlberg, and B. Mannervik Glutathione reductase Methods Enzymol. 113 1985 484 490
30. W.H. Habig, M.J. Pabst, and W.B. Jakoby Glutathione S-transferases. The first enzymatic step in mercapturic acid formation J. Biol. Chem. 249 1974 7130 7139
31. A. Wendel Glutathione peroxidase Methods Enzymol. 77 1981 325 333
32. P. Li, D. Nijhawan, I. Budihardjo, SM. Srinivasula, M. Ahmad, E.S. Alnemri, and X. Wang Cytochrome c and dATP-dependent formation of APAF-1/caspase-9 complex initiates an apoptotic protease cascade Cell 91 1997 479 489
33. S. Frosali, P. Di Simplicio, S. Perrone, D. Di Giuseppe, M. Longini, D. Tanganelli, and G. Buonocore Glutathione recycling and antioxidant enzyme activities in erythrocytes of term and preterm newborns at birth. Biol. Neonate 85 2004 188 194
34. P. Di Simplicio, F. Franconi, S. Frosali, and D. Di Giuseppe Thiolation and nitrosation of cysteines in biological fluids and cells Amino Acids 25 2003 323 339
35. P. Di Simplicio, M.G. Cacace, L. Lusini, F. Giannerini, D. Giustarini, and R. Rossi Role of protein-SH groups in redox homeostasis-The erythrocyte as a model system Arch. Biochem. Biophys. 335 1998 145 152
36. A.B. Law, N.J. Moss, E.S. Lashen, and C.G. Kathon A new single-component, broad spectrum preservative system for cosmetics and toiletries J.J. Kabara Cosmetics and Drug Preservation, Principles and Practice 1984 Marcel Dekker New York 533 557
37. E.J. Primka, and J.S. Taylor Three cases of contact allergy after chemical burns from methylchloroisothiazolinone/methylisothiazolinone: one with concomitant allergy to methyldibromoglutaronitrile/phenoxyethanol Am. J. Contact Dermat. 8 1997 43 46
38. J.M. Esteve, J. Mompo, J. Garcia de la Asuncion, J. Sastre, M. Asensi, J. Boix, J.R. Vina, J. Vina, and F.V. Pallardo Oxidative damage to mitochondrial DNA and glutathione oxidation in apoptosis: studies in vivo and in vitro FASEB J. 13 1999 1055 1064
39. L. Ghibelli, C. Fanelli, G. Rotilio, E. Lafavia, S. Coppola, C. Colussi, P. Civitareale, and M.R. Ciriolo Rescue of cells from apoptosis by inhibition of active GSH extrusion FASEB J. 1998 479 486
40. N. Sato, S. Iwata, K. Nakamura, T. Hori, K. Mori, and J. Yodoi Thiol-mediated redox regulation of apoptosis. Possible roles of cellular thiols other than glutathione in T cell apoptosis J. Immunol. 154 1995 3194 3203
41. A. Perl, P. Gergely, G. Nagy, A. Koncz, and K. Banki Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity Trends Immunol. 25 2004 360 367
42. K. Banki, E. Hutter, N.J. Gonchoroff, and A. Perl Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signalling J. Immunol. 162 1999 1466 1479
43. P.X. Petit, S.A. Susin, N. Zamzami, B. Mignotte, and G. Kroemer Mitochondria and programmed cell death: back to the future FEBS Lett. 396 1996 7 13
44. T. Dandrea, E. Bajak, L. Warngard, and I.A. Cotgreave Protein S-glutathionylation correlates to selective stress gene expression and cytoprotection Arch. Biochem. Biophys. 406 2002 241 252
45. Y.W. Know, H. Masutani, H. Nakamura, Y. Ishii, and J. Yodoi Redox regulation of cell growth and cell death Biol. Chem. 384 2003 991 996
46. C.A. Chrestensen, D.W. Starke, and J.J. Mieyal Acute cadmium exposure inactivates thioltransferase (Glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis J. Biol. Chem. 275 2000 26556 26565
47. B.R. Alexander An assessment of the comparative sensitization potential of some common isothiazolinones Contact Dermatitis 46 2002 191 196
48. M.B. Hampton, and S. Orrenius Dual regulation of caspase activity by hydrogen peroxide: implication for apoptosis FEBS Lett. 414 1997 552 556
49. C.S.I. Nobel, M. Kimland, D.W. Nicholson, S. Orrenius, and A.F.G. Slater Disulfiram is a potent inhibitor of proteases of the caspase family Chem. Res. Toxicol. 10 1997 1319 1324