Detecting association in a case-control study while correcting for population stratification

Genetic Epidemiology

Volumn 20, Issue 1, 2001, Pages 4-16

  Reich, David E ^a   Goldstein, David B ^b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Association studies; Case control studies; Population stratification; SNPs; X2 test

Indexed keywords

ARTICLE; CASE CONTROL STUDY; GENE FREQUENCY; GENETIC MARKER; GENOTYPE; POPULATION GENETICS; QUANTITATIVE GENETICS; STATISTICS;

CASE-CONTROL STUDIES; CHROMOSOME MAPPING; ETHNIC GROUPS; GENE FREQUENCY; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION BIAS;

EID: 0035185344     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2272(200101)20:1<4::AID-GEPI2>3.0.CO;2-T     Document Type: Article

References (13)

1. Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci
2. Genomic control for association studies
3. The transmission/disequilibrium test: History, subdivision, and admixture
4. A discordant-sibship test for disequilibrium and linkage: No need for parental data
5. Gene genealogies and the coalescent process
6. Genetic dissection of complex traits
7. Use of unlinked genetic markers to detect population stratification in association studies
8. Statistical properties of two tests that use multilocus data sets to detect population expansions
9. The future of genetic studies of complex human diseases
10. The future of genetic case-control studies
11. A sibship test for linkage in the presence of association: The sib transmission/disequilibrium test