Boosting with a DNA vaccine expressing ESAT-6 (DNAE6) obliterates the protection imparted by recombinant BCG (rBCGE6) against aerosol Mycobacterium tuberculosis infection in guinea pigs

Vaccine

Volumn 28, Issue 1, 2009, Pages 63-70

  Dey, Bappaditya ^a   Jain, Ruchi ^a   Khera, Aparna ^a   Rao, Vivek ^a,b   Dhar, Neeraj ^a,c   Gupta, Umesh D ^d   Katoch, V M ^d   Ramanathan, V D ^e   Tyagi, Anil K ^a  

^a UNIVERSITY OF DELHI   (India)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c EPFL   (Switzerland)

^d NATIONAL JALMA INSTITUTE FOR LEPROSY AND OTHER MYCOBACTERIAL DISEASES   (India)

^e NATIONAL INSTITUTE FOR RESEARCH IN TUBERCULOSIS   (India)

Author keywords

ESAT 6; Prime boost vaccination; Tuberculosis

Indexed keywords

BCG VACCINE; DNA VACCINE; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; INTERLEUKIN 10; RECOMBINANT BCG E6; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BCG VACCINATION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFICACY; FEMALE; GUINEA PIG; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOLOGY; LUNG TUBERCULOSIS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; SCORING SYSTEM;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BCG VACCINE; FEMALE; GUINEA PIGS; IMMUNIZATION, SECONDARY; INTERFERON-GAMMA; LUNG; MICE; MICE, INBRED BALB C; MYCOBACTERIUM TUBERCULOSIS; SPLEEN; TUBERCULOSIS, PULMONARY; VACCINES, DNA;

EID: 70849119370     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.09.121     Document Type: Article

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