Paddling mechanism for the substrate translocation by AAA+ motor revealed by multiscale molecular simulations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 43, 2009, Pages 18237-18242

  Koga, Nobuyasu ^a,b,e   Kameda, Tomoshi ^c   Okazaki, Kei Ichi ^b   Takada, Shoji ^a,b,d  

^a KYOTO UNIVERSITY   (Japan)

^b KOBE UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Coarse grained model; Fully atomistic simulation; HsIU; Molecular dynamics; Multiple basin model

Indexed keywords

ADENOSINE TRIPHOSPHATE; MOLECULAR MOTOR; POLYPEPTIDE; PROTEASOME; SIGNAL PEPTIDE;

ARTICLE; BACTERIUM; CONFORMATIONAL TRANSITION; EUKARYOTIC CELL; EUKARYOTIC SPORE; GENE TRANSLOCATION; MOLECULAR DYNAMICS; MUTATION; PRIORITY JOURNAL; SIMULATION;

COMPUTER SIMULATION; ENDOPEPTIDASE CLP; ESCHERICHIA COLI; MODELS, MOLECULAR; PROTEIN STRUCTURE, QUATERNARY; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 70849108762     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904756106     Document Type: Article

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