Clostridium septicum alpha-toxin forms pores and induces rapid cell necrosis

Toxicon

Volumn 55, Issue 1, 2010, Pages 61-72

  Knapp, Oliver ^a   Maier, Elke ^b   Ben Mkaddem, Sanae ^c   Benz, Roland ^b   Bens, Marcelle ^c   Chenal, Alexandre ^d   Geny, Blandine ^a   Vandewalle, Alain ^c   Popoff, Michel R ^a  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c INSERM   (France)

^d CNRS   (France)

Author keywords

Alpha toxin; Cell necrosis; Channel formation; Clostridium perfringens; Clostridium septicum; Lipid bilayer; Transepithelial resistance

Indexed keywords

ADENOSINE TRIPHOSPHATE; BACTERIAL TOXIN; CASPASE 3; CLOSTRIDIUM TOXIN; EPSILON TOXIN; ION CHANNEL; POTASSIUM; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE RESISTANCE; CELL PERMEABILIZATION; CELL STRAIN; CHANNEL GATING; CLOSTRIDIUM SEPTICUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; CYTOTOXICITY TEST; DNA FRAGMENTATION; ELECTRIC RESISTANCE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; ION CONDUCTANCE; ION PERMEABILITY; LIPID BILAYER; MONOLAYER CULTURE; NONHUMAN; POTASSIUM CELL LEVEL; POTASSIUM DEPLETION; POTASSIUM TRANSPORT; PRIORITY JOURNAL;

CLOSTRIDIUM PERFRINGENS; CLOSTRIDIUM SEPTICUM;

EID: 70849091488     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.06.037     Document Type: Article

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