Quantitative structureactivity relationship (QSAR) studies on a series of 1,3,4-thiadiazole-2-thione derivatives as tumor-associated carbonic anhydrase IX inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 24, Issue 3, 2009, Pages 722-729

  Abdel Hamid, Mohammed K ^a   Abdel Hafez, Atef A ^a   El Koussi, Nawal A ^a   Mahfouz, Nadia M ^a  

^a Assiut University   (Egypt)

Author keywords

1,3,4 Thiadiazole 2 thione; Carbonic anhydrase inhibitors; QSAR analysis; Topological descriptors

Indexed keywords

CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IX; THIADIAZOLE DERIVATIVE; 1,3,4 THIADIAZOLE 2 THIONE; 1,3,4-THIADIAZOLE-2-THIONE; CA9 PROTEIN, HUMAN; CARBONATE DEHYDRATASE; THIOKETONE; TUMOR ANTIGEN; TUMOR MARKER;

ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; DRUG ACTIVITY; ELECTRONICS; HUMAN; INFORMATION; LINEAR REGRESSION ANALYSIS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TUMOR; ALGORITHM; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; IC 50; METABOLISM; NEOPLASM; PATHOLOGY; STATISTICAL MODEL;

TETRA;

ALGORITHMS; ANTIGENS, NEOPLASM; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; HUMANS; INHIBITORY CONCENTRATION 50; LINEAR MODELS; MOLECULAR STRUCTURE; NEOPLASMS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES; THIONES; TUMOR MARKERS, BIOLOGICAL;

EID: 70749090754     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360802361514     Document Type: Article

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