Neuroprotective effect of 5,7,3′,4′,5′-pentahydroxy dihdroflavanol-3-O-(2″-O-galloyl)-β-d-glucopyranoside, a polyphenolic compound in focal cerebral ischemia in rat

European Journal of Pharmacology

Volumn 626, Issue 2-3, 2010, Pages 205-212

  ArunaDevi, Rathinam ^a   Lata, Suman ^b   Bhadoria, Brijesh K ^b   Ramteke, Vinod D ^a   Kumar, Saurabh ^a   Sankar, Palanisamy ^a   Kumar, Dinesh ^a   Tandan, Surendra K ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

^b INDIAN GRASSLAND AND FODDER RESEARCH INSTITUTE   (India)

Author keywords

Apoptosis; Cyclooxygenase; Focal cerebral ischemia; Free radical; Ischemia reperfusion injury; Nitrite; Oxidative stress; Polyphenolic compound

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 5,7,3',4',5' PENTAHYDROXY DIHDROFLAVANOL 3 O (2'' O GALLOYL) BETA DEXTRO GLUCOPYRASONIDE; CARBONYL DERIVATIVE; CATALASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GLUTAMIC ACID; HYDROGEN PEROXIDE; NEUROPROTECTIVE AGENT; NITRIC OXIDE; NITROGEN; PROSTAGLANDIN SYNTHASE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID BRAIN LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOGEISSUS PENDULA; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; LIPID PEROXIDATION; MEDICINAL PLANT; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BEHAVIOR, ANIMAL; BRAIN EDEMA; BRAIN ISCHEMIA; CEREBRAL INFARCTION; FLAVONOIDS; GLUCOSIDES; GLUTAMIC ACID; HYDROGEN PEROXIDE; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PHENOLS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, WISTAR; TIME FACTORS;

EID: 70649106885     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.09.038     Document Type: Article

References (46)

1. Acheson R.M., and Williams D.R.R. Does consumption of fruit and vegetables protect against stroke?. Lancet 1 (1983) 1191-1193
2. Barone F.C., and Feuerstein G.Z. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J. Cereb. Blood Flow. Metab. 19 (1999) 819-834
3. Bederson J.B., Pitts L.H., Germano S.M., Nishimura M.C., Davis R.L., and Bartkowski H. Evaluation of 2, 3, 5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 17 (1986) 1304-1308
4. Bederson J.B., Pitts L.H., Tsuji M., Nishimura M.C., Davis R.L., and Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17 (1986) 472-476
5. Bergmeyer H.U. In: Bergmeyer H.U. (Ed). Methods of Enzymatic Analysis. 3rd Ed Vol. 2 (1983) 165-166
6. Bravo L. Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nutr. Rev. 56 (1998) 317-333
7. Bronner L.L., Kanter D.S., and Manson J.E. Primary prevention of stroke. N. Engl. J. Med. 333 (1995) 1392-1400
8. Cao D.H., Xu J.F., Xue R.H., Zheng W.F., and Liu Z.L. Protective effect of chronic ethyl docosahexaenoate administration on brain injury in ischemic gerbils. Pharmacol. Biochem. Behav. 79 (2004) 651-659
9. Carden D.L., and Granger D.N. Pathophysiology of ischemia-reperfusion injury. J. Pathol. 190 (2000) 255-266
10. Choi-Kwon S., Park K., Lee H., Park M., Lee J., Jeon S., Choe M., and Park K. Temporal changes in cerebral antioxidant enzyme activities after ischemia and reperfusion in a rat focal brain ischemia model: effect of dietary fish oil. Brain Res. 152 (2004) 11-18
11. Cortas N.K., and Wakid N.W. Determination of inorganic nitrate in serum and urine by kinetic cadmium-reduction methods. Chin. Chem. 36 (1990) 1440-1443
12. Danielisová V., Gottlieb M., Némethová M., and Burda J. Activities of endogenous antioxidant enzymes in the cerebrospinal fluid and the hippocampus after transient forebrain ischemia in rat. J. Neurol. Sci. 253 (2007) 61-65
13. De Freitas G.R., and Bogousslavsky J. Primary stroke prevention. Eur. J. Neurol. 8 (2001) 1-15
14. Denizot F., and Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J. Immunol. Methods 22 (1986) 271-277
15. Dormandy T.L. An approach to free radicals in medicine and biology. Acta Physiol. Scand. 492 (1980) 153-168
16. Evans P.H. Free radicals in brain metabolism and pathology. Br. Med. Bull. 49 (1993) 577-587
17. Floyd R.A. Antioxidants, oxidative stress and degenerative neurological disorders. Proc. Soc. Exp. Biol. Med. 222 (1999) 236-245
18. Gao Z., Huang K., Yang X., and Xu H. Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. Biochim. Biophys. Acta 1472 (1999) 643-650
19. Iadecola C., and Alexander M. Cerebral ischemia and inflammation. Curr. Opin. Neurol. 14 (2001) 89-94
20. Irmak M.K., Fadillioglu E., Sogut S., Erdogan H., Gulec M., Ozer M., Yagmurca M., and Gozukara M.E. Effects of caffeic acid phenethyl ester and alpha-tocopherol on reperfusion injury in rat brain. Cell Biochem. Funct. 21 (2003) 283-289
21. Jensen E.V. Sulfhydryl-disulfide interchanges. Science 130 (1959) 1319-1323
22. Joshipura K.J., Ascherio A., Manson J.E., Stampfer M.J., Rimm E.B., Speizer F.E., Hennekens C.H., Spiegelman D., and Willett W.C. Fruit and vegetable intake in relation to risk of ischemic stroke. JAMA 282 (1999) 1233-1239
23. Kabra D., Thiyagarajan M., Kaul C.L., and Sharma S.S. Neuroprotective effect of 4-amino 1, 8-napthalimide, a poly ADP ribose polymerase inhibitor in middle cerebral artery occlusion induced focal cerebral ischemia in rat. Brain Res. Bull. 62 (2004) 425-433
24. Love S. Oxidative stress in brain ischemia. Brain Pathol. 9 (1999) 119-131
25. Nijveldt R.J., van Nood E., van Hoorn D.E.C., Boelens P.G., van Norren K., and van Leeuwen P.A.M. Flavonoids: a review of probable mechanisms of action and potential applications. Am. J. Clin. Nutr. 74 (2001) 418-425
26. Olga O., Monika R., Vladimir S., Michal D., Pavol J., Sofia Z., and Svorad S. Content of protein carbonyl groups in gerbil brain after reversible bilateral carotid occlusion: effect of 2, 3-dihydromelatonin. Neuroendocrinol. Lett. 27 (2006) 156-159
27. Ovbiagele B., Kidwell C.S., Starkman S., and Saver J.L. Neuroprotective agents for the treatment of acute ischemic stroke. Curr. Neurol. Neureactive oxygen speciesci. Rep. 3 (2003) 9-20
28. Oyaizu M. Studies on product of browning reaction prepared from glucose amine. Jap. J. Nutr. 44 (1986) 307-315
29. Paglia O.E., and Valentine W.N. Studies on the quantitative characterization of erythrocyte glutathion peroxidase. J. Lab. Clin. Med. 70 (1967) 158-169
30. Pandey M.M., Govindarajan R., Rawat A.K., and Pushpangadan P. Free radical scavenging potential of Saussurea costus. Acta Pharmacologica 55 (2005) 297-304
31. Parmentier S., Böhme G.A., Lerouet D., Damour D., Stutzmann J.M., Margaill I., and Plotkine M. Selective inhibition of inducible nitric oxide synthase prevents ischaemic brain injury. Br. J. Pharmacol. 127 (1999) 546-552
32. Raghuramulu N., Nair K.M., and Kalyanasundaram S. A Manual of Laboratory Techniques (2003), National Institutes of Nutrition, Hyderabad, India
33. Reiter R.J. Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J. 9 (1995) 526-533
34. Rice-Evans C., Nicholas J., Molwell P., Bramley P., and Pridham J. The relative antioxidant activities of plant-derived polyphenolic flavonoids. Free Radic. Res. 22 (1995) 375-383
35. Rice-Evans C.A., Miller J., and Paganga G. Antioxidant properties of phenolic compounds. Trends Plant Sci. 2 (1997) 152-159
36. Rodrigo J., Fernandez A.P., Serrano J., Peinado M.A., and Martinez A. The role of free radicals in cerebral hypoxia and ischemia. Free Radic. Biol. Med. 39 (2005) 26-50
37. Sedlak J., and Lindsay R.H. Estimation of total, protein-bound and non-protein sulphydryl groups in tissue with Ellman's reagent. Anal. Biochem. 25 (1968) 192-205
38. Shafiq-ur-Rehman. Lead-induced lipid peroxidation in brain. Toxicol. Lett. 21 (1984) 333-337
39. Shieh D.E., Liu L.T., and Lin C.C. Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res. 20 (2000) 2861-2865
40. Shinde V., Dhalwal K., Paradkar A.R., Mahadik K.R., and Kadam S.S. Evaluation of in-vitro antioxidant activity of human placental extract. Pharmacol. online 3 (2006) 172-179
41. Smrcka M., Otevrel F., Kuchickova S., HOrky M., Juran V., Duba M., and Graterol I. Experimental model of reversible focal ischemia in the rat. Scripta Medica, BLNO 74 (2001) 391-398
42. Sun A.Y., and Chen Y.M. Oxidative stress and neurodegenerative disorders. J. Biomed. Sci. 5 (1998) 401-414
43. Vollset S.E., and Bjelke E. Does consumption of fruit and vegetables protect against stroke?. Lancet 8352 (1983) 8742
44. Wang T., Qin L., Liu B., Liu Y., Wilson B., Eling T.E., Langenbach R., Taniura S., and Hong J.S. Role of reactive oxygen species in LPS-induced production of reactive oxygen species and prostaglandin E2 in microglia. J. Neurochem. 88 (2004) 939-947
45. Yazawa K., Kihara T., Shen H., Shimmyo Y., Niidome T., and Sugimoto H. Distinct mechanisms underlie distinct polyphenol-induced neuroprotection. FEBS Lett. 580 (2003) 6623-6628
46. Zhi-Jun Y., Sriranganathan N., Vaught T., Arastu S.K., and Ansar A.S. A dye based lymphocyte proliferation assay that permits multiple immunological analysis: mRNA, cytogenetic, apoptosis, and immunophenotyping studies. J. Immunol. Methods 210 (1997) 25-39