Appraisal of anti-inflammatory potential of the clubmoss, Lycopodium clavatum L.

Journal of Ethnopharmacology

Volumn 109, Issue 1, 2007, Pages 146-150

  Orhan, Ilkay ^a   Küpeli, Esra ^a   Şener, Bilge ^a   Yesilada, Erdem ^b  

^a GAZI UNIVERSITY   (Turkey)

^b YEDITEPE UNIVERSITY   (Turkey)

Author keywords

Acetic acid induced increased capillary permeability; Alkaloid; Anti inflammatory; Clubmoss; Lycopodiaceae; Lycopodium clavatum

Indexed keywords

ACETIC ACID; ACETIC ACID ETHYL ESTER; ALKALOID; ANTIINFLAMMATORY AGENT; CHLOROFORM; INDOMETACIN; LYCOPODINE; LYCOPODIUM CLAVATUM EXTRACT; METHANOL; PETROLEUM ETHER; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOASSAY; CAPILLARY PERMEABILITY; CLUBMOSS; CONTROLLED STUDY; DRUG ISOLATION; FRACTIONATION; GAS CHROMATOGRAPHY; LYCOPODIUM; MALE; MASS SPECTROMETRY; MEDICINAL PLANT; MOUSE; NONHUMAN;

ACETIC ACID; ALKALOIDS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CAPILLARY PERMEABILITY; CHROMATOGRAPHY, LIQUID; COLORING AGENTS; EVANS BLUE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; INDOMETHACIN; LYCOPODIUM; MALE; MICE; PLANT EXTRACTS; TURKEY;

LYCOPODIACEAE; LYCOPODIUM CLAVATUM;

EID: 33751402594     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.07.018     Document Type: Article

References (34)

1. Abdel-Halim O.B., Abdel-Fattah H., Halim A.F., and Murakoshi I. Comparative chemical and biological studies of the alkaloidal content of Lygos species and varieties growing in Egypt. Acta Pharmaceutica Hungaria 67 (1997) 241-247
2. Ainge G.D., Lorimer S.D., Gerard P.J., and Ruf L.D. Insecticidal activity of huperzine A from the New Zealand clubmoss, Lycopodium varium. Journal of Agriculture and Food Chemistry 50 (2002) 491-494
3. Ayer W.A. The Lycopodium alkaloids. Natural Product Reports 8 (1991) 455-463
4. Ayer W.A., and Trifonov L.S. Lycopodium alkaloids. In: Cordell G., and Brossi A. (Eds). The Alkaloids: Chemistry and Pharmacology vol. 45 (1985), Academic Press, Orlando, USA 233-266
5. Bai D. Traditional Chinese medicines and new drug development. Pure and Applied Chemistry 65 (1993) 1103-1112
6. Baytop T. Therapy with Medicinal Plants in Turkey (Past and Present). 2nd ed. (1999), Nobel Tip Kitabevleri, Istanbul, Turkey
7. Becker-Witt C., Lüdtke R., Weibhuhn T.E.R., and Willich S.N. Diagnoses and treatment in homeopathic medical practice. Forschung in Komplemantarmedisin Klass Naturheil 11 (2004) 98-103
8. Cheng D.H., Ren H., and Tang X.C. Huperzine A, a novel promising acetylcholinesterase inhibitor. Neuroreport 8 (1996) 97-101
9. Coffey T. The History and Folklore of North American Wild Flowers (1993), Houghton Mifflin Company Press, New York, USA
10. Davis P.H., and Cullen J. Lycopodium L. In: Davis P.H. (Ed). Flora of Turkey and the East Aegean Islands vol. 1 (1984), Edinburg University Press, Edinburg, UK 88-90
11. Duan H.Q., Takaishi Y., Momota H., Ohmoto Y., Taki T., Jia Y.F., and Li D. Immunosuppressive sesquiterpene alkaloids from Tripterygium wilfordii. Journal of Natural Products 64 (2001) 582-587
12. Friese K.H. Homeopathic therapy of otitis media in children. Monats Kinderheil 152 (2004) 734-735
13. Friese K.H., Kruse S., Lüdtke R., and Moeller H. The homeopathic treatment of otitis media in children-comparisons with conventional therapy. International Journal of Clinical and Pharmacological Therapy 35 (1997) 296-301
14. Gebhardt R. Antioxidative, antiproliferative and biochemical effects in HepG2 cells of a homeopathic remedy and its constituent plant tinctures tested separately or in combination. Arzneimittel Forschung/Drug Research 53 (2003) 823-830
15. Gerard R., and MacLean D.B. GC/MS examination of four Lycopodium species for alkaloid content. Phytochemistry 25 (1986) 1143-1150
16. Holdsworth D.K., and Giheno J. A preliminary survey of highland medicinal plants. Science in New Guinea 3 (1975) 191-198
17. Hu T., and Chandler R.F. Obscurinine: a new Lycopodium alkaloid. Tetrahedron Letters 28 (1987) 5993-5996
18. Kulip J. A preliminary survey of traditional medicinal plants in the west coast and interior of Sabah. Journal of Tropical Forest Science 10 (1997) 271-274
19. Küpeli E., Kosar M., Yesilada E., and Baser K.H.C. A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. Life Sciences 72 (2002) 645-652
20. Lawrence G.H.M. Taxonomy of Vascular Plants (1989), MacMillan Publishing Co., New York, USA pp. 337-338
21. Lema W.J., Blakenship J.W., and Malone M.H. Prostaglandin synthetase inhibition by alkaloids of Heimia salicifolia. Journal of Ethnopharmacology 42 (1986) 161-167
22. Liu J.S., and Huang M.F. The alkaloids huperzines C and D and huperzinine from Lycopodiastrum casuarinoides. Phytochemistry 37 (1994) 1759-1761
23. Liu J.S., Zhu Y.L., Yu C.M., Zhou Y.Z., Han Y.Y., Wu F.W., and Qi B.F. The structures of huperzine A and B, two new alkaloids exhibiting marked anticholinesterase activity. Canadian Journal of Chemistry 64 (1986) 837-839
24. Ma X.Q., Jiang S.H., and Zhu D.Y. Alkaloid patterns in Huperzia and some related genera of Lycopodiaceae sensu lato occurring in China and their contribution to classification. Biochemical Systematics and Ecology 26 (1998) 723-728
25. MacLean D.B. Lycopodium alkaloids. In: Brossi A. (Ed). The Alkaloids: Chemistry and Pharmacology vol. 26 (1985), Academic Press, Orlando 241-298
26. Morita H., Hirasawa Y., Shinzato T., and Kobayashi J. New phlegmarane-type, cernuane-type, and quinolizidine alkaloids from two species of Lycopodium. Tetrahedron 60 (2004) 7015-7023
27. Qian B.C., Wang M., Zhou Z.F., Chen K., Zhou R.R., and Chen G.S. Pharmacokinetics of tablet huperzine A in six volunteers. Acta Pharmacologica Sinica 16 (1995) 396-398
28. Sparg S.G., Light M.E., and van Staden J. Biological activities and distribution of plant saponins. Journal of Ethnopharmacology 94 (2004) 219-243
29. Tang X.C. Huperzine A (shuangyiping): a promising drug for Alzheimer's disease. Acta Pharmacologica Sinica 17 (1996) 481-484
30. Vasudeva S.M. Economic importance of pteridophytes. Indian Fern Journal 16 (1999) 130-152
31. Wen D., Liu Y., Li W., and Liu H. Separation methods for antibacterial and antirheumatismal agents in plant medicines. Journal of Chromatography B 812 (2004) 101-117
32. Yesilada E., Tanaka S., Sezik E., and Tabata M. Isolation of anti-inflammatory principle from the fruit juice of Ecbalium elaterium. Journal of Natural Products 51 (1988) 504-508
33. Yin W., Wang T.S., Yin F.Z., and Cai B.C. Analgesic and anti-inflammatory properties of brucine and brucine-N-oxide extracted from seeds of Strychnos nux-vomica. Journal of Ethnopharmacology 88 (2003) 205-214
34. Zhi Q.X., and Xi C.T. Effect of huperzine A, a novel acetylcholinesterase inhibitor, on radial maze performance in rats. Pharmacology Biochemistry and Behavior 51 (1995) 415-429