Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity

Vaccine

Volumn 28, Issue 1, 2009, Pages 243-255

  Luo, Dongjiao ^a,b   Xue, Feng ^a   Ojcius, David M ^c   Zhao, Jinfang ^a   Mao, Yafei ^a   Li, Liwei ^a   Lin, Xuai ^a   Yan, Jie ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b HANGZHOU NORMAL UNIVERSITY   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Immunoprotection; Leptospira; Lipoproteins

Indexed keywords

ANTISERUM; BACTERIAL ANTIGEN; BACTERIAL VACCINE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LEPTOSPIRA INTERROGANS VACCINE; OUTER MEMBRANE PROTEIN LIPL32; UNCLASSIFIED DRUG;

AGGLUTINATION TEST; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ANTIGEN DETECTION; ANTIGEN SPECIFICITY; ARTICLE; BACTERIAL GENE; BACTERIAL OUTER MEMBRANE; BACTERIAL STRAIN; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE SEQUENCE; GENUS; HUMAN; IMMUNOGENICITY; INFECTION PREVENTION; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; MICROSCOPY; MOLECULAR TYPING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ALIGNMENT; SEROTYPE;

AGGLUTINATION TESTS; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; CROSS REACTIONS; DNA, BACTERIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GUINEA PIGS; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LEPTOSPIRA; LEPTOSPIROSIS; LIPOPROTEINS; MOLECULAR SEQUENCE DATA; PHYLOGENY; SEQUENCE ALIGNMENT;

EID: 70649088857     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.09.089     Document Type: Article

References (63)

1. Bharti A.R., Nally J.E., Ricaldi J.N., Matthias M.A., Diaz M.M., Lovett M.A., et al. Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis 3 12 (2003) 757-771
2. McBride A.J., Athanazio D.A., Reis M.G., and Ko A.I. Leptospirosis. Curr Opin Infect Dis 18 5 (2005) 376-386
3. Levett P.N. Leptospirosis. Clin Microbiol Rev 14 2 (2001) 296-326
4. Viriyakosol S., Matthias M.A., Swancutt M.A., Kirkland T.N., and Vinetz J.M. Toll-like receptor 4 protects against lethal Leptospira interrogans serovar icterohaemorrhagiae infection and contributes to in vivo control of leptospiral burden. Infect Immun 74 2 (2006) 887-895
5. Sehgal S.C., Sugunan A.P., and Vijayachari P. Outbreak of leptospirosis after the cyclone in Orissa. Natl Med J India 15 1 (2002) 22-23
6. Barcellos C., and Sabroza P.C. The place behind the case: leptospirosis risks and associated environmental conditions in a flood-related outbreak in Rio de Janeiro. Cad Saude Publica 17 Suppl. (2001) 59-67
7. Fuortes L., and Nettleman M. Leptospirosis: a consequence of the Iowa flood. Iowa Med 84 10 (1994) 449-450
8. Faine S., Adher B., Bloin C., and Perolat P. Leptospira and leptospirosis. 2nd ed. (1999), MedSci, Melbourne, Australia
9. Sejvar J., Bancroft E., Winthrop K., Bettinger J., Bajani M., Bragg S., et al. Leptospirosis in "Eco-Challenge" athletes, Malaysian Borneo, 2000. Emerg Infect Dis 9 6 (2003) 702-707
10. Bolin C.A., Cassells J.A., Zuerner R.L., and Trueba G. Effect of vaccination with a monovalent Leptospira interrogans serovar hardjo type hardjo-bovis vaccine on type hardjo-bovis infection of cattle. Am J Vet Res 52 10 (1991) 1639-1643
11. Samina I., Brenner J., Moalem U., Berenstein M., Cohen A., and Peleg B.A. Enhanced antibody response in cattle against Leptospira hardjo by intradermal vaccination. Vaccine 15 12-13 (1997) 1434-1436
12. Chapman A.J., Faine S., and Adler B. Antigens recognized by the human immune response to vaccination with a bivalent hardjo/Pomona leptospiral vaccine. FEMS Microbiol Immunol 2 2 (1990) 111-118
13. Campagnolo E.R., Warwick M.C., Marx Jr. H.L., Cowart R.P., Donnell Jr. H.D., Bajani M.D., et al. Analysis of the 1998 outbreak of leptospirosis in Missouri in humans exposed to infected swine. J Am Vet Med Assoc 216 5 (2000) 676-682
14. Venkataraman K.S., and Nedunchelliyan S. Epidemiology of an outbreak of leptospirosis in man and dog. Comp Immunol Microbiol Infect Dis 15 4 (1992) 243-247
15. Cullen P.A., Haake D.A., and Adler B. Outer membrane proteins of pathogenic spirochetes. FEMS Microbiol Rev 28 3 (2004) 291-318
16. Haake D.A., and Matsunaga J. Characterization of the leptospiral outer membrane and description of three novel leptospiral membrane proteins. Infect Immun 70 9 (2002) 4936-4945
17. Cullen P.A., Cordwell S.J., Bulach D.M., Haake D.A., and Adler B. Global analysis of outer membrane proteins from Leptospira interrogans serovar Lai. Infect Immun 70 5 (2002) 2311-2318
18. Gebriel A.M., Subramaniam G., and Sekaran S.D. The detection and characterization of pathogenic Leptospira and the use of OMPs as potential antigens and immunogens. Trop Biomed 23 2 (2006) 194-207
19. Cullen P.A., Cu X., Matsunaga J., Sanchez Y., Ko A.I., Haake D.A., et al. Sufaceome of Leptospira spp. Infect Immun 73 8 (2005) 4853-4863
20. Cullen P.A., Haake D.A., Bulach D.M., Zuerner R.L., and Adler B. LipL21 is a novel surface-exposed lipoprotein of pathogenic Leptospira species. Infect Immun 71 5 (2003) 2414-2421
21. Haake D.A., Chao G., Zuerner R.L., Barnett J.K., Barnett D., Mazel M., et al. The leptospiral major outer membrane protein LipL32 is a lipoprotein expressed during mammalian infection. Infect Immun 68 4 (2000) 2276-2285
22. Haake D.A., Martinich C., Summers T.A., Shang E.S., Pruetz J.D., McCoy A.M., et al. Characterization of leptospiral outer membrane and lipoprotein LipL36: downregulation associated with late-log-phase growth and mammalian infection. Infect Immun 66 4 (1998) 1579-1587
23. Shang E.S., Summers T.A., and Haake D.A. Molecular cloning and sequence analysis of the gene encoding LipL41, a surface-exposed lipoprotein of pathogenic Leptospira species. Infect Immun 64 6 (1996) 2322-2330
24. Matsunaga J., Young T.A., Barnett J.K., Barnett D., Bolin C.A., and Haake D.A. Novel 45-kilodalton leptospiral protein that is processed to a 31-kilodalton growth-phase-regulated peripheral membrane protein. Infect Immun 70 1 (2002) 323-334
25. Matsunaga J., Werneid K., Zuerner R.L., Frank A., and Haake D.A. LipL46 is a novel surface-exposed lipoprotein expressed during leptospiral dissemination in the mammalian host. Microbiology 152 Pt (12) (2006) 3777-3786
26. Hoke D.E., Egan S., Cullen P.A., and Adler B. LipL32 is an extracellular matrix-interacting protein of Leptospira spp. and Pseudoalteromonas tunicata. Infect Immun 76 5 (2008) 2063-2069
27. Murray G.L., Srikram A., Hoke D.E., Wunder Jr. E.A., Henry R., Lo M., et al. Major surface protein LipL32 is not required for either acute or chronic infection with Leptospira interrogans. Infect Immun 77 3 (2009) 952-958
28. Hauk P., Macedo F., Romero E.C., Vasconcellos S.A., de Morais Z.M., Barbosa A.S., et al. In LipL32, the major leptospiral lipoprotein, the C terminus is the primary immunogenic domain and mediates interaction with collagen IV and plasma fibronectin. Infect Immun 76 6 (2008) 2642-2650
29. Haake D.A., Mazel M.K., McCoy A.M., Milward F., Chao G., Matsunaga J., et al. Leptospiral outer membrane proteins OmpL1 and LipL41 exhibit synergistic immunoprotection. Infect Immun 67 12 (1999) 6572-6582
30. Kobayashi Y. Clinical observation and treatment of leptospirosis. J Infect Chemother 7 2 (2001) 59-68
31. Dai B. Advances in research on leptospira and human leptospirosis in China. Chin Med Sci J 7 4 (1992) 239-243
32. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., and Higgins D.G. The Clustsal X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25 24 (1997) 4876-4882
33. Kumar S., Tamura K., and Nei M. MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment. Brief Bioinform 5 2 (2004) 150-163
34. Jameson B.A., and Wolf H. The antigenic index: a novel algorithm for predicting antigenic determinants. Comput Appl Biosci 4 1 (1988) 181-186
35. Lilie H., Schwarz E., and Rudolph R. Advances in refolding of proteins produced in E. coli. Curr Opin Biotechnol 9 5 (1998) 497-501
36. Singh S.M., and Panda A.K. Solubilization and refolding of bacterial inclusion body proteins. J Biosci Bioeng 99 4 (2005) 303-310
37. Zhang X.Y., Yu Y., He P., Zhang Y.X., Hu B.Y., Yang Y., et al. Expression and comparative analysis of genes encoding outer membrane proteins LipL21, LipL32 and OmpL1 in epidemic leptospires. Acta Biochim Biophys Sin 37 10 (2005) 649-656
38. Lewis S.M., and Osei-Bimpong A. Haemoglobinometry in general practice. Clin Lab Haematol 25 6 (2003) 343-346
39. Wild C.J., Greenlee J.J., Bolin C.A., Barnett J.K., Haake D.A., and Cheville N.E. An improved immunohistochemical diagnostic technique for canine leptospirosis using antileptospiral antibodies on renal tissue. J Vet Diagn Invest 14 1 (2002) 20-24
40. Wright C.L., and Kelly J.K. The use of routine special stains for upper gastrointestinal biopsies. Am J Surg Pathol 30 3 (2006) 357-361
41. Langston C.E., and Heuter K.J. Leptospirosis: a re-emerging zoonotic disease. Vet Clin North Am Small Anim Pract 33 4 (2003) 791-807
42. Sonrier C., Branger C., Michel V., Ruvoen-Clouet N., Ganiere J.P., and Andre-Fontaine G. Evidence of cross-protection within Leptospira interrogans in an experimental model. Vaccine 19 1 (2000) 86-94
43. Thongboonkerd V. Proteomics in leptospirosis research: towards molecular diagnostics and vaccine development. Expert Rev Mol Diagn 8 1 (2008) 53-61
44. Wang Z., Jin L., and Wegrzyn A. Leptospirosis vaccines. Microb Cell Fact 6 1 (2007) 39
45. Priya C.G., Rathinam S.R., and Muthukkaruppan V. Evidence for endotoxin as a causative factor for leptospiral uveitis in humans. Invest Ophthalmol Vis Sci 49 12 (2008) 5419-5424
46. Palaniappan R.U., Ramanujam S., and Chang Y.F. Leptospirosis: pathogenesis, immunity, and diagnosis. Curr Opin Infect Dis 20 3 (2007) 284-292
47. Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N., Wilson P.J., et al. Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis. PLoS ONE 3 2 (2008) e1607
48. Adler B., and Faine S. Serological and protective antibody responses of rabbits to leptospiral antigens. J Med Microbiol 11 4 (1978) 401-409
49. Adler B., and Faine S. A Pomona serogroup-specific, agglutinating antigen in Leptospira, identified by monoclonal antibodies. Pathology 15 3 (1983) 247-250
50. Masuzawa T., Nakamura R., Shimizu T., Iwamoto Y., Morita T., and Yanagihara Y. Immunological characteristics of the glycolipid antigen of Leptospira interrogans serovar lai. Infect Immun 57 8 (1989) 2502-2506
51. Da Silva J.J., Netto B.A., Lilembaum W., Alvim M.E., and De Oliveira A.V. The hemorrhagic syndrome of leptospirosis: an experimental study in guinea pigs. Rev Soc Bras Med Trop 28 3 (1995) 169-177
52. Nally J.E., Chantranuwat C., Wu X.Y., Fishbein M.C., Pereira M.M., Da Silva J.J., et al. Alveolar septal deposition of immunoglobulin and complement parallels pulmonary hemorrhage in a guinea pig model of severe pulmonary leptospirosis. Am J Pathol 164 3 (2004) 1115-1127
53. Lourdault K., Aviat F., and Picardeau M. Use of quantitative real-time PCR for studying the dissemination of Leptospira interrogans in the guinea pig infection model of leptospirosis. J Med Microbiol 58 5 (2009) 648-655
54. Moon J.E., Ellis M.W., Griffith M.E., Hawley J.S., Rivard R.G., McCall S., et al. Efficacy of macrolides and telithromycin against leptospirosis in a hamster model. Antimicrob Agents Chemother 50 6 (2006) 1989-1992
55. Griffith M.E., Moon J.E., Johnson E.N., Clark K.P., Hawley J.S., Hospenthal D.R., et al. Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model. Antimicrob Agents Chemother 51 7 (2007) 2615-2617
56. Jost B.H., Adler B., and Faine S. Experimental immunisation of hamsters with lipopolysaccharide antigens of Leptospira interrogans. J Med Microbiol 29 2 (1989) 115-120
57. Branger C., Chatrenet B., Gauvrit A., Aviat F., Aubert A., Bach J.M., et al. Protection against Leptospira interrogans sensu lato challenge by DNA immunization with the gene encoding hemolysin-associated protein 1. Infect Immun 73 7 (2005) 4062-4069
58. Silva E.F., Medeiros M.A., McBride A.J., Matsunaga J., Esteves G.S., Ramos J.G., et al. The terminal portion of Leptospiral immunoglobulin-like protein LigA confers protective immunity against lethal infection in the hamster model of leptospirosis. Vaccine 25 33 (2007) 6277-6286
59. Dong H.Y., Hu Y., Xue F., Sun D., Ojcius D.M., Mao Y.-F., et al. Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein. BMC Microbiol 8 223 (2008) 223-234
60. Guerreiro H., Croda J., Flannery B., Mazel M., Matsunaga J., Reis M.G., et al. Leptospiral proteins recognized during the humoral immune response to leptospirosis in humans. Infect Immun 69 8 (2001) 4958-4968
61. Palaniappan R.U.M., McDonough S.P., Divers T.J., Chen C.-S., Pan M.-J., Matsumoto M., et al. Immunoprotection of recombinant leptospiral immunoglobulin-like protein A against Leptospira interrogans Serovar Pomona infection. Infect Immun 74 3 (2006) 1745-1750
62. Yan W., Faisal S.M., McDonough S.P., Divers T.J., Barr S.C., Chang C.F., et al. Immunogenicity and protective efficacy of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model. Microbes Infect 11 2 (2009) 230-237
63. Faisal S.M., Yan W., McDonough S.P., and Chang Y.F. Leptospira immunoglobulin-like protein A variable region (LigAvar) incorporated in liposomes and PLGA microspheres produces a robust immune response correlating to protective immunity. Vaccine 27 3 (2009) 378-387