Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis

Journal of Biological Chemistry

Volumn 284, Issue 46, 2009, Pages 31807-31816

  Henkel, Anne S ^a,b   Elias, Marc S ^a   Green, Richard M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAUSAL RELATIONSHIPS; CHOLESTEROL ACCUMULATION; ESSENTIAL COMPONENT; HEPATIC STEATOSIS; HEPG2 CELLS; HOMOCYSTEINES; HYPERHOMOCYSTEINEMIA; PATHOPHYSIOLOGIC; S-ADENOSYLMETHIONINE; THAPSIGARGINS; UNFOLDED PROTEIN RESPONSE; WEIGHT LOSS;

ECOLOGY; PROTEINS;

NUTRITION;

ALANINE AMINOTRANSFERASE; CYCLOLEUCINE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HOMOCYSTEINE; S ADENOSYLMETHIONINE; SMALL INTERFERING RNA; THAPSIGARGIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DIET SUPPLEMENTATION; FATTY LIVER; GENE EXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN STRUCTURE; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELLS, CULTURED; CHOLINE DEFICIENCY; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; FATTY LIVER; FEMALE; HOMOCYSTEINE; LIVER; LIVER NEOPLASMS; METHIONINE; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; S-ADENOSYLMETHIONINE; UNFOLDED PROTEIN RESPONSE;

MURINAE; MUS;

EID: 70450270564     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.017970     Document Type: Article

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