Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria

Malaria Journal

Volumn 8, Issue 1, 2009, Pages

  Naka, Izumi ^a   Nishida, Nao ^b   Patarapotikul, Jintana ^c   Nuchnoi, Pornlada ^c   Tokunaga, Katsushi ^b   Hananantachai, Hathairad ^c   Tsuchiya, Naoyuki ^a   Ohashi, Jun ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; CYTOKINE;

ARTICLE; CHROMOSOME 5Q; GENE CLUSTER; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HAPLOTYPE; HUMAN; INFECTION SENSITIVITY; MAJOR CLINICAL STUDY; MALARIA; PLASMODIUM FALCIPARUM; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; THAILAND; ADOLESCENT; ADULT; ANIMAL; CHROMOSOME 5; FEMALE; GENETIC PREDISPOSITION; GENETICS; MALARIA FALCIPARUM; MALE; MULTIGENE FAMILY;

ADOLESCENT; ADULT; ANIMALS; CHROMOSOMES, HUMAN, PAIR 5; CYTOKINES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; INTERLEUKIN-13; MALARIA, FALCIPARUM; MALE; MULTIGENE FAMILY; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; THAILAND; YOUNG ADULT;

EID: 70450265563     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-8-232     Document Type: Article

References (26)

1. Linkage and association between Plasmodium falciparum blood infection levels and chromosome 5q31-q33. L Flori B Kumulungui C Aucan C Esnault AS Traore F Fumoux P Rihet, Genes Immun 2003 4 265 268 10.1038/sj.gene.6363960 12761562
2. Linkage analysis of blood Plasmodium falciparum levels: interest of the 5q31-q33 chromosome region. A Garcia S Marquet B Bucheton D Hillaire M Cot N Fievet AJ Dessein L Abel, Am J Trop Med Hyg 1998 58 705 709 9660449 (Pubitemid 28307384)
3. Malaria in humans: Plasmodium falciparum blood infection levels are linked to chromosome 5q31-q33. P Rihet Y Traore L Abel C Aucan T Traore-Leroux F Fumoux, Am J Hum Genet 1998 63 498 505 10.1086/301967 9683598 (Pubitemid 30418631)
4. Genetic determination and linkage mapping of Plasmodium falciparum malaria related traits in Senegal. A Sakuntabhai R Ndiaye I Casademont C Peerapittayamongkol C Rogier P Tortevoye A Tall R Paul C Turbpaiboon W Phimpraphi JF Trape A Spiegel S Heath O Mercereau-Puijalon A Dieye C Julier, PLoS ONE 2008 3 2000 10.1371/journal.pone.0002000 18431485
5. Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. S Marquet L Abel D Hillaire H Dessein J Kalil J Feingold J Weissenbach AJ Dessein, Nat Genet 1996 14 181 184 10.1038/ng1096-181 8841190
6. Genes at human chromosome 5q31.1 regulate delayed-type hypersensitivity responses associated with Leishmania chagasi infection. SM Jeronimo AK Holst SE Jamieson R Francis DR Martins FL Bezerra NA Ettinger ET Nascimento GR Monteiro HG Lacerda EN Miller HJ Cordell P Duggal TH Beaty JM Blackwell ME Wilson, Genes Immun 2007 8 539 551 10.1038/sj.gene.6364422 17713557
7. A single-nucleotide substitution from C to T at position -1055 in the IL-13 promoter is associated with protection from severe malaria in Thailand. J Ohashi I Naka J Patarapotikul H Hananantachai S Looareesuwan K Tokunaga, Genes Immun 2003 4 528 531 10.1038/sj.gene.6364010 14551608
8. Further development of multiplex single nucleotide polymorphism typing method, the DigiTag2 assay. N Nishida T Tanabe M Takasu A Suyama K Tokunaga, Anal Biochem 2007 364 78 85 10.1016/j.ab.2007.02.005 17359929
9. Linkage disequilibrium structure of the 5q31-33 region in a Thai population. P Nuchnoi J Ohashi I Naka D Nacapunchai K Tokunaga N Nishida J Patarapotikul, J Hum Genet 2008 53 850 856 10.1007/s10038-008-0309-8 18574552
10. Haploview: analysis and visualization of LD and haplotype maps. JC Barrett B Fry J Maller MJ Daly, Bioinformatics 2005 21 263 265 10.1093/bioinformatics/bth457 15297300
11. The Mre11 complex: at the crossroads of dna repair and checkpoint signalling. D D'Amours SP Jackson, Nat Rev Mol Cell Biol 2002 3 317 327 10.1038/nrm805 11988766
12. The cellular response to DNA double-strand breaks: defining the sensors and mediators. JH Petrini TH Stracker, Trends Cell Biol 2003 13 458 462 10.1016/S0962-8924(03)00170-3 12946624
13. The MRN complex: coordinating and mediating the response to broken chromosomes. M van den Bosch RT Bree NF Lowndes, EMBO Rep 2003 4 844 849 10.1038/sj.embor.embor925 12949583
14. Nibrin functions in Ig class-switch recombination. S Kracker Y Bergmann I Demuth PO Frappart G Hildebrand R Christine ZQ Wang K Sperling M Digweed A Radbruch, Proc Natl Acad Sci USA 2005 102 1584 1589 10.1073/pnas.0409191102 15668383
15. The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions. M Yabuki MM Fujii N Maizels, Nat Immunol 2005 6 730 736 10.1038/ni1215 15937485
16. TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. D Kwiatkowski AV Hill I Sambou P Twumasi J Castracane KR Manogue A Cerami DR Brewster BM Greenwood, Lancet 1990 336 1201 1204 10.1016/0140-6736(90)92827-5 1978068
17. Coordinate regulation of the IL-4, IL-13, and IL-5 cytokine cluster in Th2 clones revealed by allelic expression patterns. BL Kelly RM Locksley, J Immunol 2000 165 2982 2986 10975806
18. Chromatin structure and gene regulation in the immune system. ST Smale AG Fisher, Annu Rev Immunol 2002 20 427 462 10.1146/annurev.immunol.20.100301. 064739 11861609
19. Regulation of the Th2 cytokine locus by a locus control region. GR Lee PE Fields TJ Griffin RA Flavell, Immunity 2003 19 145 153 10.1016/S1074-7613(03) 00179-1 12871646
20. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. T Heinemeyer E Wingender I Reuter H Hermjakob AE Kel OV Kel EV Ignatieva EA Ananko OA Podkolodnaya FA Kolpakov NL Podkolodny NA Kolchanov, Nucleic Acids Res 1998 26 362 367 10.1093/nar/26.1.362 9399875
21. Variants in the 5q31 cytokine gene cluster are associated with psoriasis. M Chang Y Li C Yan KP Callis-Duffin N Matsunami VE Garcia M Cargill D Civello N Bui JJ Catanese MF Leppert GG Krueger AB Begovich SJ Schrodi, Genes Immun 2008 9 176 181 10.1038/sj.gene.6364451 18075513
22. Contribution of functional variation in the IL13 gene to allergy, hay fever and asthma in the NSHD longitudinal 1946 birth cohort. S Black AS Teixeira AX Loh L Vinall JW Holloway R Hardy DM Swallow, Allergy 2009 64 1172 1178 10.1111/j.1398-9995.2009.01988.x 19254294
23. Interleukin-13 promoter gene polymorphism -1112C/T is associated with the systemic form of mastocytosis. B Nedoszytko M Niedoszytko M Lange J van Doormaal J Glen M Zablotna J Renke A Vales F Buljubasic E Jassem J Roszkiewicz P Valent, Allergy 2009 64 287 294 10.1111/j.1398-9995.2008.01827.x 19178408
24. Analysis of polymorphisms in olive pollen allergy: IL13, IL4RA, IL5 and ADRB2 genes. E Llanes J Quiralte E Lopez B Sastre M Chacartegui V del Pozo P Palomino C Lahoz B Cardaba, Int Arch Allergy Immunol 2009 148 228 238 10.1159/000161583 18849614
25. Th2 cell-selective enhancement of human IL13 transcription by IL13-1112C>T, a polymorphism associated with allergic inflammation. L Cameron RB Webster JM Strempel P Kiesler M Kabesch H Ramachandran L Yu DA Stern PE Graves IC Lohman AL Wright M Halonen WT Klimecki D Vercelli, J Immunol 2006 177 8633 8642 17142763
26. An IL-13 promoter polymorphism associated with increased risk of allergic asthma. TC van der Pouw Kraan A van Veen LC Boeije SA van Tuyl ER de Groot SO Stapel A Bakker CL Verweij LA Aarden JS van der Zee, Genes Immun 1999 1 61 65 10.1038/sj.gene.6363630 11197307