-
1
-
-
0031759864
-
The HER-2/neu oncogene in breast cancer: Prognostic factor, predictive factor, and target for therapy
-
Ross JS. Fletcher JA. The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Stem Cells 1998; 16 (6): 413-428 (Pubitemid 28524507)
-
(1998)
Stem Cells
, vol.16
, Issue.6
-
-
Ross, J.S.1
Fletcher, J.A.2
-
2
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG, et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987;235(4785): 177-182
-
(1987)
Science
, vol.235
, Issue.4785
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
-
3
-
-
0034773992
-
The EGFR family and its ligands in human cancer: Signalling mechanisms and therapeutic opportunities
-
PII S0959804901002301
-
Yarden Y. The EGFR family and its ligands in human cancer: signalling mechanisms and therapeutic opportunities. Eur J Cancer 2001 ; 37 Suppl. 4: S3-8 (Pubitemid 32938123)
-
(2001)
European Journal of Cancer
, vol.37
, Issue.SUPPL. 4
-
-
Yarden, Y.1
-
5
-
-
0034789517
-
Receptor tyrosine kinase signalling as a target for cancer intervention strategies
-
DOI 10.1677/erc.0.0080161
-
Zwick EJ, Bange J, Ullrich A. Receptor tyrosine kinase signalling as a target for cancer intervention strategies. Endocr Relat Cancer 2001; 8 (3): 161-173 (Pubitemid 32947638)
-
(2001)
Endocrine-Related Cancer
, vol.8
, Issue.3
-
-
Zwick, E.1
Bange, J.2
Ullrich, A.3
-
6
-
-
5644252971
-
Molecular approach to breast cancer treatment
-
DOI 10.1053/j.seminoncol.2004.07.016, PII S009377540400363X
-
Yarden Y, Baselga J, Miles D. Molecular approach to breast cancer treatment. Semin Oncol 2004: 31 (5 Suppl. 10): 6-13 (Pubitemid 39370104)
-
(2004)
Seminars in Oncology
, vol.31
, Issue.SUPPL. 10
-
-
Yarden, Y.1
Baselga, J.2
Miles, D.3
-
8
-
-
2342488965
-
Update on HER-2 as a target for cancer therapy: Intracellular signaling pathways of ErbB2/HER-2 and family members
-
Olayioye MA. Update on HER-2 as a target for cancer therapy: intracellular signaling pathways of ErbB2/HER-2 and family members. Breast Cancer Res 2001; 3 (6): 385-389
-
(2001)
Breast Cancer Res
, vol.3
, Issue.6
-
-
Olayioye, M.A.1
-
9
-
-
0030944455
-
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
-
DOI 10.1093/emboj/16.7.1647
-
Graus-Porta D, Beerli RR. Daly JM, et al. ErbB-2, the preferred hetero- dimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBOJ 1997; 16(7): 1647-1655 (Pubitemid 27151960)
-
(1997)
EMBO Journal
, vol.16
, Issue.7
-
-
Graus-Porta, D.1
Beerli, R.R.2
Daly, J.M.3
Hynes, N.E.4
-
10
-
-
0033608993
-
The erbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors
-
DOI 10.1073/pnas.96.9.4995
-
Klapper LN, Glathe S, Vaisman N, et al. The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors. Proc Natl Acad Sci U S A 1999; 96 (9): 4995-5000 (Pubitemid 29214524)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.9
-
-
Klapper, L.N.1
Glathe, S.2
Vaisman, N.3
Hynes, N.E.4
Andrews, G.C.5
Sela, M.6
Yarden, Y.7
-
11
-
-
0037429779
-
The deaf and the dumb: The biology of ErbB-2 and ErbB-3
-
DOI 10.1016/S0014-4827(02)00101-5
-
Citri A, Skaria KB, Yarden Y. The deaf and the dumb: the biology of ErbB-2 and ErbB-3. Exp Cell Res 2003; 284 (1): 54-65 (Pubitemid 36342255)
-
(2003)
Experimental Cell Research
, vol.284
, Issue.1
-
-
Citri, A.1
Skaria, K.B.2
Yarden, Y.3
-
12
-
-
19444366195
-
Molecular modeling of nearly full-length ErbB2 receptor
-
DOI 10.1529/biophysj.104.046003
-
Bagossi P, Horvath G, Vereb G, et al. Molecular modeling of nearly full-length ErbB2 receptor. Biophys J 2005; 88 (2): 1354-1363 (Pubitemid 40975962)
-
(2005)
Biophysical Journal
, vol.88
, Issue.2
-
-
Bagossi, P.1
Horvath, G.2
Vereb, G.3
Szollosi, J.4
Tozser, J.5
-
13
-
-
10744230127
-
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors
-
DOI 10.1016/S1097-2765(03)00350-2
-
Burgess AW, Cho HS, Eigenbrot C, et al. An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. Mol Cell 2003; 12 (3): 541-552 (Pubitemid 37222478)
-
(2003)
Molecular Cell
, vol.12
, Issue.3
-
-
Burgess, A.W.1
Cho, H.-S.2
Eigenbrot, C.3
Ferguson, K.M.4
Garrett, T.P.J.5
Leahy, D.J.6
Lemmon, M.A.7
Sliwkowski, M.X.8
Ward, C.W.9
Yokoyama, S.10
-
14
-
-
12144266330
-
Hsp90 restrains ErbB-2/HER2 signalling by limiting heterodimer formation
-
DOI 10.1038/sj.embor.7400300
-
Citri A, Gan J, Mosesson Y, et al. Hsp 90 restrains ErbB-2/HER2 signalling by limiting heterodimer formation. EMBO Rep 2004; 5 (12): 1165-1170 (Pubitemid 40103611)
-
(2004)
EMBO Reports
, vol.5
, Issue.12
-
-
Citri, A.1
Gan, J.2
Mosesson, Y.3
Vereb, G.4
Szollosi, J.5
Yarden, Y.6
-
15
-
-
0028168569
-
Insect cell-expressed pl80erbB3 possesses an impaired tyrosine kinase activity
-
Guy PM, Platko JV, Cantley LC, et al. Insect cell-expressed pl80erbB3 possesses an impaired tyrosine kinase activity. Proc Natl Acad Sci U S A 1994; 91 (17): 8132-8136
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, Issue.17
-
-
Guy, P.M.1
Platko, J.V.2
Cantley, L.C.3
-
16
-
-
0038575385
-
Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer
-
DOI 10.1002/path.1370
-
Witton CJ, Reeves JR, Going JJ, et al. Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer. J Pathol 2003: 200 (3): 290-297 (Pubitemid 36827302)
-
(2003)
Journal of Pathology
, vol.200
, Issue.3
-
-
Witton, C.J.1
Reeves, J.R.2
Going, J.J.3
Cooke, T.G.4
Barlett, J.M.S.5
-
17
-
-
33745714207
-
The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells
-
Naresh A, Long W, Vidal GA, et al. The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells. Cancer Res 2006; 66 ( 12): 6412-6420
-
(2006)
Cancer Res
, vol.66
, Issue.12
-
-
Naresh, A.1
Long, W.2
Vidal, G.A.3
-
18
-
-
33846296953
-
A constitutively active ERBB4/HER4 allele with enhanced transcriptional coactivation and cell-killing activities
-
DOI 10.1038/sj.onc.1209794, PII 1209794
-
Vidal GA, Clark DE, Marrero L, et al. A constitutively active ERBB4/HER4 allele with enhanced transcriptional coactivation and cell-killing activities. Oncogene 2007; 26(3): 462-466 (Pubitemid 46122836)
-
(2007)
Oncogene
, vol.26
, Issue.3
-
-
Vidal, G.A.1
Clark, D.E.2
Marrero, L.3
Jones, F.E.4
-
19
-
-
21244487829
-
Presenilin-dependent γ-secretase processing regulates multiple ERBB4/HER4 activities
-
DOI 10.1074/jbc.M412457200
-
Vidal GA, Naresh A, Marrero L, et al. Presenilin-dependent gamma-secretase processing regulates multiple ERBB4/HER4 activities. J Biol Chem 2005; 280(20): 19777-19783 (Pubitemid 41379503)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.20
-
-
Vidal, G.A.1
Naresh, A.2
Marrero, L.3
Jones, F.E.4
-
20
-
-
0035868342
-
Her-2/neu overexpression induces NF-κB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IκB-α that can be inhibited by the tumor suppressor PTEN
-
DOI 10.1038/sj.onc.1204257
-
Pianetti S, Arsura M, Romieu-Mourez R, et al. Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene 2001; 20 (11): 1287-1299 (Pubitemid 32269934)
-
(2001)
Oncogene
, vol.20
, Issue.11
-
-
Pianetti, S.1
Arsura, M.2
Romieu-Mourez, R.3
Coffey, R.J.4
Sonenshein, G.E.5
-
21
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA, et al. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000: 19 (13): 3159-3167
-
(2000)
EMBO J
, vol.19
, Issue.13
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
-
22
-
-
24044520039
-
EGFR gene amplification in breast cancer: Correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations
-
DOI 10.1038/modpathol.3800438
-
Bhargava R, Gerald WL, Li AR, et al. EGFR gene amplification in breast cancer: correlation with epidermal growth factor receptor mRN A and protein expression and HER-2 status and absence of EGFR-activating mutations. Mod Pathol 2005; 18 (8): 1027-1033 (Pubitemid 41224492)
-
(2005)
Modern Pathology
, vol.18
, Issue.8
-
-
Bhargava, R.1
Gerald, W.L.2
Li, A.R.3
Pan, Q.4
Lal, P.5
Ladanyi, M.6
Chen, B.7
-
24
-
-
0032142749
-
ErbB3 (HER3) interaction with the p85 regulatory subunit of phosphoinositide 3-kinase
-
Hellyer NJ, Cheng K, Koland JG. ErbB3 (HER3) interaction with the p85 regulatory subunit of phosphoinositide 3-kinase. Biochem J 1998; 333 (Pt 3): 757-763 (Pubitemid 28398546)
-
(1998)
Biochemical Journal
, vol.333
, Issue.3
-
-
Hellyer, N.J.1
Cheng, K.2
Koland, J.G.3
-
25
-
-
0030030072
-
ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: Implications for breast cancer
-
Karunagaran D, Tzahar E, Beerli RR, et al. ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer. EMBO J 1996; 15 (2): 254-264 (Pubitemid 26029205)
-
(1996)
EMBO Journal
, vol.15
, Issue.2
-
-
Karunagaran, D.1
Tzahar, E.2
Beerli, R.R.3
Chen, X.4
Graus-Porta, D.5
Ratzkin, B.J.6
Seger, R.7
Hynes, N.E.8
Yarden, Y.9
-
26
-
-
0028823802
-
Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2
-
Beerli RR, Graus-Porta D, Woods-Cook K, et al. Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2. Mol Cell Biol 1995; 15 (12): 6496-6505
-
(1995)
Mol Cell Biol
, vol.15
, Issue.12
-
-
Beerli, R.R.1
Graus-Porta, D.2
Woods-Cook, K.3
-
27
-
-
0034707581
-
ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases
-
DOI 10.1083/jcb.148.2.385
-
Spencer KS, Graus-Porta D, Leng J, et al. ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases. J Cell Biol 2000; 148 (2): 385-397 (Pubitemid 30078250)
-
(2000)
Journal of Cell Biology
, vol.148
, Issue.2
-
-
Spencer, K.S.1
Graus-Porta, D.2
Leng, J.3
Hynes, N.E.4
Klemke, R.L.5
-
28
-
-
0031840484
-
ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner
-
Olayioye MA, Graus-Porta D, Beerli RR, et al. ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner. Mol Cell Biol 1998: 18 (9): 5042-5051 (Pubitemid 28388087)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.9
-
-
Olayioye, M.A.1
Graus-Porta, D.2
Beerli, R.R.3
Rohrer, J.4
Gay, B.5
Hynes, N.E.6
-
29
-
-
0033546315
-
ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases
-
Olayioye MA, Beuvink I, Horsch K, et al. ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases. J Biol Chem 1999; 274 (24): 17209-17218 (Pubitemid 129519056)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.24
-
-
Olayioye, M.A.1
Beuvink, I.2
Horsch, K.3
Daly, J.M.4
Hynes, N.E.5
-
30
-
-
0042307325
-
The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
-
DOI 10.1073/pnas.1537685100
-
Holbro T, Beerli RR, Maurer F, et al. The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc Natl Acad Sci U S A 2003; 100 (15): 8933-8938 (Pubitemid 36899201)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.15
-
-
Holbro, T.1
Beerli, R.R.2
Maurer, F.3
Koziczak, M.4
Barbas III, C.F.5
Hynes, N.E.6
-
31
-
-
0029053716
-
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas
-
Alimandi M, Romano A, Curia MC, et al. Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene 1995: 10(9): 1813-1821
-
(1995)
Oncogene
, vol.10
, Issue.9
-
-
Alimandi, M.1
Romano, A.2
Curia, M.C.3
-
32
-
-
0029804204
-
The relationship between human epidermal growth-like factor receptor expression and cellular transformation in NIH3T3 cells
-
DOI 10.1074/jbc.271.48.30897
-
Cohen BD, Kiener PA, Green JM, et al. The relationship between human epidermal growth-like factor receptor expression and cellular transformation in NIH3T3 cells. J Biol Chem 1996; 271 (48): 30897-30903 (Pubitemid 26404114)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.48
-
-
Cohen, B.D.1
Kiener, P.A.2
Green, J.M.3
Foy, L.4
Perry Fell, H.5
Zhang, K.6
-
33
-
-
0029162564
-
Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3
-
Wallasch C, Weiss FU, Niederfellner G, et al. Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3. EMBO J 1995; 14 (17): 4267-4275
-
(1995)
EMBO J
, vol.14
, Issue.17
-
-
Wallasch, C.1
Weiss, F.U.2
Niederfellner, G.3
-
34
-
-
0030064531
-
Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2
-
DOI 10.1074/jbc.271.7.3884
-
Zhang K, Sun J, Liu N, et al. Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 orHER2. J Biol Chem 1996; 271 (7): 3884-3890 (Pubitemid 26065710)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.7
-
-
Zhang, K.1
Sun, J.2
Liu, N.3
Wen, D.4
Chang, D.5
Thomason, A.6
Yoshinaga, S.K.7
-
35
-
-
0025804023
-
Monoclonal antibody therapy of human cancer: Taking the HER2 protooncogene to the clinic
-
Shepard HM. Lewis GD. Sarup JC, et al. Monoclonal antibody therapy of human cancer: taking the HER2 protooncogene to the clinic. J Clin Immunol 1991; 11 (3): 117-127
-
(1991)
J Clin Immunol
, vol.11
, Issue.3
-
-
Shepard, H.M.1
Lewis, G.D.2
Sarup, J.C.3
-
36
-
-
0037434791
-
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
-
DOI 10.1038/nature01392
-
Cho HS, Mason K, Ramyar KX, et al. Structure of the extracellular region of H ER2 alone and in complex with the Herceptin Fab. Nature 2003; 421 (6924): 756-760 (Pubitemid 36227628)
-
(2003)
Nature
, vol.421
, Issue.6924
-
-
Cho, H.-S.1
Mason, K.2
Ramyar, K.X.3
Stanley, A.M.4
Gabelli, S.B.5
Denney Jr., D.W.6
Leahy, D.J.7
-
37
-
-
33746118320
-
Trastuzumab and breast cancer: Developments and current status
-
DOI 10.1007/s10147-006-0575-4
-
Tokunaga E, Oki E, Nishida K, et al. Trastuzumab and breast cancer: devel- opments and current status. Int J Clin Oncol 2006; 11 (3): 199-208 (Pubitemid 44087118)
-
(2006)
International Journal of Clinical Oncology
, vol.11
, Issue.3
-
-
Tokunaga, E.1
Oki, E.2
Nishida, K.3
Koga, T.4
Egashira, A.5
Morita, M.6
Kakeji, Y.7
Maehara, Y.8
-
38
-
-
0026610881
-
Humanization of an anti-p185HER2 antibody for human cancer therapy
-
Carter P, Presta L, Gorman CM. et al. Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc Natl Acad Sci U S A 1992; 89 (10): 4285-4289
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, Issue.10
-
-
Carter, P.1
Presta, L.2
Gorman, C.M.3
-
39
-
-
0034760143
-
Herceptin® alone or in combination with chemotherapy in the treatment of HER2-positive metastatic breast cancer: Pivotal trials
-
Baselga J. Herceptin alone or in combination with chemotherapy in the treatment of HER2-positive metastatic breast cancer: pivotal trials. Oncology 2001; 61 Suppl. 2: 14-21 (Pubitemid 33033420)
-
(2001)
Oncology
, vol.61
, Issue.SUPPL. 2
-
-
Baselga, J.1
-
40
-
-
0035125614
-
Clinical trials of Herceptin (trastuzumab)
-
37 SUPPL.
-
Baselga J. Clinical trials of Herceptin (trastuzumab). Eur J Cancer 2001; 37 Suppl. 1: S18-24
-
(2001)
Eur J Cancer
, vol.1
-
-
Baselga, J.1
-
41
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart MJ, Procter M, Leyland-Jones B, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005; 353(16): 1659-1672
-
(2005)
N Engl J Med
, vol.353
, Issue.16
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
-
42
-
-
64549147357
-
BCIRG 006: Docetaxel and trastuzumab-based regimens improve DFS and OS over AC-T in node positive and high risk node negative HER2 positive early breast cancer patients: quality of life (QOL) at 36 months follow-up [abstract no. 19647]
-
19647 [online] [Accessed2009Oct23]
-
Robert NJ, Eiermann W, Pienkowski T, et al. BCIRG 006: docetaxel and trastuzumab-based regimens improve DFS and OS over AC-T in node positive and high risk node negative HER2 positive early breast cancer patients: quality of life (QOL) at 36 months follow-up [abstract no. 19647]. J Clin Oncol 2007; 25 (18 Suppl.): 719s [online]. Available from URL: http://meeting. ascopubs.org/cgi/content/abstract/25/18-suppl ' 19647 [Accessed 2009 Oct 23]
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 SUPPL.
-
-
Robert, N.J.1
Eiermann, W.2
Pienkowski, T.3
-
44
-
-
33845886440
-
Lapatinib plus capecitabine for HER2positive advanced breast cancer
-
Geyer CE, Forster J, Lindquist D, et al. Lapatinib plus capecitabine for HER2positive advanced breast cancer. N Engl J Med 2006: 355 (26): 2733-2743
-
(2006)
N Engl J Med
, vol.355
, Issue.26
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
-
45
-
-
56549113680
-
A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: Updated efficacy and biomarker analyses
-
Cameron D. Casey M. Press M, et al. A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses. Breast Cancer Res Treat 2008; 112 (3): 533-543
-
(2008)
Breast Cancer Res Treat
, vol.112
, Issue.3
-
-
Cameron, D.1
Casey, M.2
Press, M.3
-
46
-
-
35948951183
-
Pathologic complete response to trastuzumab-based neoadjuvant therapy is related to the level of HER-2 amplification
-
Amould L., Arveux P, Couturier J, et al. Pathologic complete response to trastuzumab-based neoadjuvant therapy is related to the level of HER-2 amplification. Clin Cancer Res 2007; 13 (21): 6404-6409
-
(2007)
Clin Cancer Res
, vol.13
, Issue.21
-
-
Amould, L.1
Arveux, P.2
Couturier, J.3
-
47
-
-
66249091930
-
The HER-2 receptor and breast cancer: Ten years of targeted anti-HER-2 therapy and personalized medicine
-
Ross JS, Slodkowska EA. Symmans WF, et al. The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine. Oncologist 2009; 14 (4): 320-368
-
(2009)
Oncologist
, vol.14
, Issue.4
-
-
Ross, J.S.1
Slodkowska, E.A.2
Symmans, W.F.3
-
48
-
-
28244432561
-
Insulin-like growth factor-I receptor/ human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells
-
Nahta R. Yuan LX, Zhang B, et al. Insulin-like growth factor-I receptor/ human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells. Cancer Res 2005; 65 (23): 11118-11128
-
(2005)
Cancer Res
, vol.65
, Issue.23
-
-
Nahta, R.1
Yuan, L.X.2
Zhang, B.3
-
49
-
-
0035915421
-
Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)
-
Lu Y, Zi X, Zhao Y, et al. Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). J Natl Cancer Inst 2001: 93 (24): 1852-1857
-
(2001)
J Natl Cancer Inst
, vol.93
, Issue.24
-
-
Lu, Y.1
Zi, X.2
Zhao, Y.3
-
50
-
-
0141956319
-
Her-2/neu-triggered intracellular tyrosine kinase activation: In vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment
-
Hudelist G, Köstler WJ, Attems J, et al. Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment. Br J Cancer 2003;89(6):983-991
-
(2003)
Br J Cancer
, vol.89
, Issue.6
-
-
Hudelist, G.1
Köstler, W.J.2
Attems, J.3
-
51
-
-
62449280788
-
Quantitation of HER2 expression or HER2: HER2 dimers and differential survival in a cohort of metastatic breast cancer patients carefully selected for trastuzumab treatment primarily by FISH
-
Desmedt C., Sperinde J, Piette F, et al. Quantitation of HER2 expression or HER2: HER2 dimers and differential survival in a cohort of metastatic breast cancer patients carefully selected for trastuzumab treatment primarily by FISH. Diagn Mol Pathol 2009; 18 (1): 22-29
-
(2009)
Diagn Mol Pathol
, vol.18
, Issue.1
-
-
Desmedt, C.1
Sperinde, J.2
Piette, F.3
-
52
-
-
49749107169
-
Fluorescence-based methods in the study of protein-protein interactions in living cells
-
Ciruela F. Fluorescence-based methods in the study of protein-protein interactions in living cells. Curr Opin Biotechnol 2008; 19 (4): 338-343
-
(2008)
Curr Opin Biotechnol
, vol.19
, Issue.4
-
-
Ciruela, F.1
-
53
-
-
0034846540
-
Imaging protein-protein interactions using fluorescence resonance energy transfer microscopy
-
DOI 10.1006/meth.2001.1189
-
Kenworthy AK. Imaging protein-protein interactions using fluorescence resonance energy transfer microscopy. Methods 2001 ; 24 (3): 289-296 (Pubitemid 32846434)
-
(2001)
Methods
, vol.24
, Issue.3
-
-
Kenworthy, A.K.1
-
54
-
-
0037674062
-
Phase II trial of ZD 1839 in recurrent or metastatic squamous cell carcinoma of the head and neck
-
Cohen EE. Rosen F, Stadler WM, et al. Phase II trial of ZD 1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 2003; 21 (10): 1980-1987
-
(2003)
J Clin Oncol
, vol.21
, Issue.10
-
-
Cohen, E.E.1
Rosen, F.2
Stadler, W.M.3
-
55
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
DOI 10.1200/JCO.20.3.719
-
Vogel CL. Cobleigh MA. Tripathy D, et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002; 20 (3): 719-726 (Pubitemid 34111379)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.3
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
Shak, S.11
Stewart, S.J.12
Press, M.13
-
56
-
-
51449112583
-
HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells
-
Kong A, Calleja V, Leboucher P, et al. HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells. PLoS ONE 2008; 3 (8): e2881
-
(2008)
PLoS ONE
, vol.3
, Issue.8
-
-
Kong, A.1
Calleja, V.2
Leboucher, P.3
-
57
-
-
62449323761
-
A novel proximity assay for the detection of proteins and protein complexes: Quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffinembedded cell lines and breast cancer tissue
-
Shi Y, Huang W, Tan Y, et al. A novel proximity assay for the detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffinembedded cell lines and breast cancer tissue. Diagn Mol Pathol 2009: 18(1): 11-21
-
(2009)
Diagn Mol Pathol
, vol.18
, Issue.1
-
-
Shi, Y.1
Huang, W.2
Tan, Y.3
-
58
-
-
0034638920
-
HER2/neu: Mechanisms of dimerization/oligomerization
-
Brennan PJ, Kumagai T, Berezov A, et al. HER2/neu: mechanisms of dimerization/oligomerization. Oncogene 2000: 19 (53): 6093-6101
-
(2000)
Oncogene
, vol.19
, Issue.53
-
-
Brennan, P.J.1
Kumagai, T.2
Berezov, A.3
-
59
-
-
0036255761
-
Protein detection using proximity-dependent DNA ligation assays
-
DOI 10.1038/nbt0502-473
-
Fredriksson S. Gullberg M, Jarvius J, et al. Protein detection using proximitydependent DNA ligation assays. Nat Biotechnol 2002; 20 (5): 473-477 (Pubitemid 34495933)
-
(2002)
Nature Biotechnology
, vol.20
, Issue.5
-
-
Fredriksson, S.1
Gullberg, M.2
Jarvius, J.3
Olsson, C.4
Pietras, K.5
Gustafsdottir, S.M.6
Ostman, A.7
Landegren, U.8
-
60
-
-
77949532395
-
The use of proximity ligation assay to identify HER2: HER3 heterodimers in early breast cancers [abstract]
-
abstract no. 2068
-
Spears M, Munro AF, Taylor KJ, et al. The use of proximity ligation assay to identify HER2: HER3 heterodimers in early breast cancers [abstract]. Cancer Research 2009: 69 (2 Suppl.): abstract no. 2068
-
(2009)
Cancer Research
, vol.69
, Issue.SUPPL.
-
-
Spears, M.1
Munro, A.F.2
Taylor, K.J.3
|