IL-6, but not IFN-γ, triggers apoptosis and inhibits in vivo growth of human malignant T cells on STAT3 silencing

Leukemia

Volumn 23, Issue 11, 2009, Pages 2102-2108

  Regis, G ^a,b   Icardi, L ^a   Conti, L ^a,b   Chiarle, R ^a   Piva, R ^a   Giovarelli, M ^a,b   Poli, V ^b   Novelli, F ^a,b  

^a MOLINETTE HOSPITAL   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; STAT1 PROTEIN; STAT3 PROTEIN;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; GENE SILENCING; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; RNA INTERFERENCE; T LYMPHOCYTE;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; GENES, MHC CLASS I; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-6; LYMPHOMA, T-CELL; MICE; MICE, SCID; NEOPLASM TRANSPLANTATION; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES;

EID: 70450247099     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2009.139     Document Type: Article

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