ADP signaling in vascular endothelial cells: ADP-dependent activation of the endothelial isoform of nitric-oxide synthase requires the expression but not the kinase activity of AMP-activated protein kinase

Journal of Biological Chemistry

Volumn 284, Issue 47, 2009, Pages 32209-32224

  Hess, Connie Ng ^a   Kou, Ruqin ^a   Johnson, Rosalyn P ^a   Li, Gordon K ^a   Michel, Thomas ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMP-ACTIVATED PROTEIN KINASE; AMPK ACTIVITY; CARDIO-VASCULAR DISEASE; CLINICAL USE; DEPHOSPHORYLATIONS; ENZYME INHIBITORS; ISOFORMS; KINASE ACTIVITY; NITRIC-OXIDE SYNTHASE; PHOSPHOINOSITIDES; RECEPTOR ANTAGONISTS; SIGNALING PATHWAYS; SMALL INTERFERING RNA (SIRNA); VASCULAR ENDOTHELIAL CELLS; WORTMANNIN;

BLOOD VESSEL PROSTHESES; CYTOLOGY; ENZYME ACTIVITY; ENZYMES; NUCLEIC ACIDS; PHOSPHORYLATION; PROTEINS; RNA; SELF ASSEMBLY; SIGNALING; SULFUR COMPOUNDS;

ENDOTHELIAL CELLS;

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ADENOSINE DIPHOSPHATE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CYCLOSPORIN A; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN KINASE C INHIBITOR; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y1 RECEPTOR; RAC1 PROTEIN; SERINE; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPHOSPHORYLATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; GENE TARGETING; IC 50; NONHUMAN; NUCLEOTIDE SEQUENCE; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; VASCULAR ENDOTHELIUM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOSINE DIPHOSPHATE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BENZIMIDAZOLES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CATTLE; CELL MOVEMENT; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; NAPHTHALIMIDES; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROTEIN ISOFORMS; SIGNAL TRANSDUCTION;

EID: 70450233529     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.032656     Document Type: Article

References (58)

1. Burnstock, G. (2007) Cell. Mol. Life Sci. 64, 1471-1483
2. Dubyak, G. R., and el-Moatassim, C. (1993) Am. J. Physiol. Cell Physiol. 265, C577-C606
3. Drury, A. N., and Szent-Györgyi, A. (1929) J. Physiol. 68, 213-237
4. Erlinge, D., and Burnstock, G. (2008) Purinergic Signal. 4, 1-20
5. Yamamoto, K., Sokabe, T., Matsumoto, T., Yoshimura, K., Shibata, M., Ohura, N., Fukuda, T., Sato, T., Sekine, K., Kato, S., Isshiki, M., Fujita, T., Kobayashi, M., Kawamura, K., Masuda, H., Kamiya, A., and Ando, J. (2006) Nat. Med. 12, 133-137
6. Pillois, X., Chaulet, H., Belloc, I., Dupuch, F., Desgranges, C., and Gadeau, Ä. P. (2002) Circ. Res. 90, 678-681
7. Kaczmarek, E., Erb, L., Koziak, K., Jarzyna, R., Wink, M. R., Guckelberger, O., Blusztajn, J. K., Trinkaus-Randall, V., Weisman, G. A., and Robson, S. C. (2005) Thromb. Haemost. 93, 735-742
8. da Silva, C. G., Specht, A., Wegiel, B., Ferran, C., and Kaczmarek, E. (2009) Circulation 119, 871-879
9. Wihlborg, A. K., Wang, L., Braun, O. O., Eyjolfsson, A., Gustafsson, R., Gudbjartsson, T., and Erlinge, D. (2004) Arterioscler. Thromb. Vasc. Biol. 24, 1810-1815
10. Shen, J., and DiCorleto, P. E. (2008) Circ. Res. 102, 448-456
11. LeRoy, E. C., Ager, A., and Gordon, J. L. (1984) J. Clin. Investig. 74, 1003-1010
12. Dudzinski, D. M., and Michel, T. (2007) Cardiovasc. Res. 75, 247-260
13. Mount, P. F., Kemp, B. E., and Power, D. A. (2007) J. Mol. Cell. Cardiol. 42, 271-279
14. Fulton, D., Gratton, J. P., McCabe, T. J., Fontana, J., Fujio, Y., Walsh, K., Franke, T. F., Papapetropoulos, A., and Sessa, W. C. (1999) Nature 399, 597-601
15. Chen, Z. P., Mitchelhill, K. I., Michell, B. J., Stapleton, D., Rodriguez-Crespo, I., Witters, L. A., Power, D. A., Ortiz de Montellano, P. R., and Kemp, B. E. (1999) FEBS Lett. 443, 285-289
16. Michell, B. J., Chen, Z. p., Tiganis, T., Stapleton, D., Katsis, F., Power, D. A., Sim, A. T., and Kemp, B. E. (2001) J. Biol. Chem. 276, 17625-17628
17. Gélinas, D. S., Bernatchez, P. N., Rollin, S., Bazan, N. G., and Sirois, M. G. (2002) Br. J. Pharmacol. 137, 1021-1030
18. Butt, E., Bernhardt, M., Smolenski, A., Kotsonis, P., Fröhlich, L. G., Sickmann, A., Meyer, H. E., Lohmann, S. M., and Schmidt, H. H. (2000) J. Biol. Chem. 275, 5179-5187
19. Partovian, C., Zhuang, Z., Moodie, K., Lin, M., Ouchi, N., Sessa W. C., Walsh, K., and Simons, M. (2005) Circ. Res. 97, 482-487
20. Sud, N., Wedgwood, S., and Black, S. M. (2008) Am. J. Physiol. Lung Cell. Mol. Physiol. 294, L582-L591
21. Cale, J. M., and Bird, I. M. (2006) Biochem. J. 398, 279-288
22. Stahmann, N., Woods, A., Carling, D., and Heller, R. (2006) Mol. Cell. Biol. 26, 5933-5945
23. Hu, Y. L., Li, S., Miao, H., Tsou, T. C., del Pozo, M. A., and Chien, S. (2002) J. Vasc. Res. 39, 465-476
24. Waschke, J., Drenckhahn, D., Adamson, R. H., and Curry, F. E. (2004) Am. J. Physiol. Heart Circ. Physiol. 287, H704-H711
25. Gonzalez, E., Kou, R., and Michel, T. (2006) J. Biol. Chem. 281, 3210-3216
26. Loscalzo, J., and Welch, G. (1995) Prog. Cardiovasc. Dis. 38, 87-104
27. Ziche, M., Morbidelli, L., Masini, E., Amerini, S., Granger, H. J., Maggi, C. A., Geppetti, P., and Ledda, F. (1994) J. Clin. Investig. 94, 2036-2044
28. Michel, T., Li, G. K., and Busconi, L. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 6252-6256
29. Gonzalez, E., Nagiel, A., Lin, A. J., Golan, D. E., and Michel, T. (2004) J. Biol. Chem. 279, 40659-40669
30. Levine, Y. C., Li, G. K., and Michel, T. (2007) J. Biol. Chem. 282, 20351-20364
31. Kou, R., and Michel, T. (2007) J. Biol. Chem. 282, 32719-32729
32. Kou, R., Igarashi, J., and Michel, T. (2002) Biochemistry 41, 4982-4988
33. Busconi, L., and Michel, T. (1993) J. Biol. Chem. 268, 8410-8413
34. Robinson, L. J., and Michel, T. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 11776-11780
35. Mills, D. C., Robb, I. A., and Roberts, G. C. (1968) J. Physiol. 195, 715-729
36. Gordon, J. L. (1986) Biochem. J. 233, 309-319
37. Baurand, A., and Gachet, C. (2003) Cardiovasc. Drug Rev. 21, 67-76
38. Shimokawa, H., Flavahan, N. A., and Vanhoutte, P. M. (1991) Circulation 83, 652-660
39. Haynes, M. P., Li, L., Sinha, D., Russell, K. S., Hisamoto, K., Baron, R., Collinge, M., Sessa, W. C., and Bender, J. R. (2003) J. Biol. Chem. 278, 2118-2123
40. Kou, R., Greif, D., and Michel, T. (2002) J. Biol. Chem. 277, 29669-29673
41. Kou, R., Sartoretto, J., and Michel, T. (2009) J. Biol. Chem. 284, 14734-14743
42. Kim, E. K., Miller, I., Aja, S., Landree, L. E., Pinn, M., McFadden, J., Kuhajda, F. P., Moran, T. H., and Ronnett, G. V. (2004) J. Biol. Chem. 279, 19970-19976
43. Burnstock, G. (2002) Arterioscler. Thromb. Vasc. Biol. 22, 364-373
44. da Silva, C. G., Jarzyna, R., Specht, A., and Kaczmarek, E. (2006) Circ. Res. 98, e39-e47
45. Buvinic, S., Briones, R., and Huidobro-Toro, J. P. (2002) Br. J. Pharmacol. 136, 847-856
46. Guns, P. J., Korda, A., Crauwels, H. M., Van Assche, T., Robaye, B., Boeynaems, J. M., and Bult, H. (2005) Br. J. Pharmacol. 146, 288-295
47. Li, C., Ruan, L., Sood, S. G., Papapetropoulos, A., Fulton, D., and Venema, R. C. (2007) Vascul. Pharmacol. 47, 257-264
48. Zhang, H., Weir, B. K., Marton, L. S., Lee, K. S., and Macdonald, R. L. (1997) J. Cardiovasc. Pharmacol. 30, 767-774
49. Boo, Y. C., Sorescu, G., Boyd, N., Shiojima, I., Walsh, K., Du, J., and Jo, H. (2002) J. Biol. Chem. 277, 3388-3396
50. Armesilla, A. L., Lorenzo, E., Gómez del Arco, P., Martínez-Martínez, S., Alfranca, A., and Redondo, J. M. (1999) Mol. Cell. Biol. 19, 2032-2043
51. Reihill, J. A., Ewart, M. A., Hardie, D. G., and Salt, I. P. (2007) Biochem. Biophys. Res. Commun. 354, 1084-1088
52. Hardie, D. G. (2008) FEBS Lett. 582, 81-89
53. Woods, A., Vertommen, D., Neumann, D., Turk, R., Bayliss, J., Schlattner, U., Wallimann, T., Carling, D, and Rider, M. H. (2003) J. Biol. Chem. 278, 28434-28442
54. Hurley, R. L., Barré, L. K., Wood, S. D., Anderson, K. A., Kemp, B. E., Means, A. R., and Witters, L. A. (2006) J. Biol. Chem. 281, 36662-36672
55. Maddika, S., and Chen, J. (2009) Nat. Cell Biol. 11, 409-419
56. Jia, S., Liu, Z., Zhang, S., Liu, P., Zhang, L., Lee, S. H., Zhang, J., Signoretti, S., Loda, M., Roberts, T. M., and Zhao, J. J. (2008) Nature 454, 776-779
57. Hirsch, E., Braccini, L., Ciraolo, E., Morello, F., and Perino, A. (2009) Trends Biochem. Sci. 34, 244-248
58. Morrow, V. A., Foufelle, F., Connell, J. M., Petrie, J. R., Gould, G. W., and Salt, I. P. (2003) J. Biol. Chem. 278, 31629-31639