Mutational and inhibitory analysis of a catalytic antibody. Implication for drug discovery

Molecular Immunology

Volumn 47, Issue 2-3, 2009, Pages 348-356

  Phichith, Denis ^a   Bun, Sylvie ^a   Padiolleau Lefèvre, Séverine ^a   Banh, Soun ^a   Thomas, Daniel ^a   Friboulet, Alain ^a   Avalle, Bérangère ^a  

^a UNIVERSITÉ DE TECHNOLOGIE DE COMPIÈGNE   (France)

Author keywords

Lactamase; Anti idiotype; Catalytic antibody; Cyclic peptide; Idiotypic network; scFv

Indexed keywords

BETA LACTAMASE; CATALYTIC ANTIBODY; PROLINE; SOLVENT; SYNTHETIC PEPTIDE; TRYPTOPHAN;

ANALYTIC METHOD; ARTICLE; AUTOIMMUNE DISEASE; BACTERIAL CELL; BACTERIAL STRAIN; CATALYSIS; CATALYST; CELL FRACTIONATION; ELECTROPHORESIS; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FLUORESCENCE; KINETICS; MOLECULAR CLONING; MOLECULAR MODEL; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS; SURFACE PLASMON RESONANCE;

AMINO ACID SEQUENCE; ANTIBODIES, CATALYTIC; BIOCATALYSIS; DNA MUTATIONAL ANALYSIS; DRUG DISCOVERY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENCE; IMMUNOGLOBULIN LIGHT CHAINS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; SURFACE PLASMON RESONANCE; TRANSITION TEMPERATURE;

ESCHERICHIA COLI;

EID: 70450225057     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.09.011     Document Type: Article

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