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Volumn 180, Issue 11, 2008, Pages 7714-7720

Factor VIII hydrolysis mediated by anti-factor VIII autoantibodies in acquired hemophilia

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 ANTIBODY; IMMUNOGLOBULIN G; ALLOANTIBODY; AUTOANTIBODY; CATALYTIC ANTIBODY;

EID: 47249156490     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.11.7714     Document Type: Article
Times cited : (41)

References (42)
  • 1
    • 0033678960 scopus 로고    scopus 로고
    • Acquired factor VIII autoantibody inhibitors: Current concepts and potential therapeutic strategies for the future
    • Kessler, C. M. 2000. Acquired factor VIII autoantibody inhibitors: current concepts and potential therapeutic strategies for the future. Haematologica 85: 57-61.
    • (2000) Haematologica , vol.85 , pp. 57-61
    • Kessler, C.M.1
  • 3
    • 33847411624 scopus 로고    scopus 로고
    • Acquired hemophilia A in the United Kingdom: A 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation
    • Collins, P. W., S. Hirsch, T. P. Baglin, G. Dolan, J. Hanley, M. Makris, D. M. Keeling, R. Liesner, S. A. Brown, and C. R. Hay. 2007. Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation. Blood 109: 1870-1877.
    • (2007) Blood , vol.109 , pp. 1870-1877
    • Collins, P.W.1    Hirsch, S.2    Baglin, T.P.3    Dolan, G.4    Hanley, J.5    Makris, M.6    Keeling, D.M.7    Liesner, R.8    Brown, S.A.9    Hay, C.R.10
  • 4
    • 0026344390 scopus 로고    scopus 로고
    • Green, D.I991. Cytotoxic suppression of acquired factor VIII:C inhibitors. Am. J. Med. 91: 14S-19S.
    • Green, D.I991. Cytotoxic suppression of acquired factor VIII:C inhibitors. Am. J. Med. 91: 14S-19S.
  • 5
    • 0027405692 scopus 로고
    • Use of porcine factor VIII in the treatment of patients with acquired hemophilia
    • Morrison, A. E., C. A. Ludlam, and C. Kessler. 1993. Use of porcine factor VIII in the treatment of patients with acquired hemophilia. Blood 81: 1513-1520.
    • (1993) Blood , vol.81 , pp. 1513-1520
    • Morrison, A.E.1    Ludlam, C.A.2    Kessler, C.3
  • 6
    • 0035822038 scopus 로고    scopus 로고
    • The hemophilias: From royal genes to gene therapy
    • Mannucci, P. M., and E. G. Tuddenham. 2001. The hemophilias: from royal genes to gene therapy. N. Engl. J. Med. 344: 1773-1779.
    • (2001) N. Engl. J. Med , vol.344 , pp. 1773-1779
    • Mannucci, P.M.1    Tuddenham, E.G.2
  • 11
  • 12
    • 0029072696 scopus 로고
    • Natural catalytic antibodies: Peptide-hydrolyzing activities of Bence Jones proteins and VL fragments
    • Paul, S., L. Li, R. Kalaga, P. Wilkins-Stevens, F. J. Stevens, and A. Solomon. 1995. Natural catalytic antibodies: peptide-hydrolyzing activities of Bence Jones proteins and VL fragments. J. Biol. Chem. 270: 15257-15261.
    • (1995) J. Biol. Chem , vol.270 , pp. 15257-15261
    • Paul, S.1    Li, L.2    Kalaga, R.3    Wilkins-Stevens, P.4    Stevens, F.J.5    Solomon, A.6
  • 20
    • 0035823022 scopus 로고    scopus 로고
    • Complement-independent, peroxide-induced antibody lysis of platelets in HIV-1-related immune thrombocytopenia
    • Nardi, M., S. Tomlinson, M. A. Greco, and S. Karpatkin. 2001. Complement-independent, peroxide-induced antibody lysis of platelets in HIV-1-related immune thrombocytopenia. Cell 106: 551-561.
    • (2001) Cell , vol.106 , pp. 551-561
    • Nardi, M.1    Tomlinson, S.2    Greco, M.A.3    Karpatkin, S.4
  • 22
    • 0019501541 scopus 로고
    • A survey of 215 non-hemophilic patients with inhibitors to factor VIII
    • Green, D., and K. Lechner. 1981. A survey of 215 non-hemophilic patients with inhibitors to factor VIII. Thromb. Haemostasis 45: 200-203.
    • (1981) Thromb. Haemostasis , vol.45 , pp. 200-203
    • Green, D.1    Lechner, K.2
  • 24
    • 0014051255 scopus 로고
    • The immunologic character of acquired inhibitors of antihe-mophiliac globulin (Factor VIII) and the kinetics of their interaction with FVIII
    • Shapiro, S. 1967. The immunologic character of acquired inhibitors of antihe-mophiliac globulin (Factor VIII) and the kinetics of their interaction with FVIII. J. Clin. Invest. 46: 147-156.
    • (1967) J. Clin. Invest , vol.46 , pp. 147-156
    • Shapiro, S.1
  • 25
    • 0023274159 scopus 로고
    • Factor VIII inhibitor IgG subclass and FVIII polypeptide specificity determined by immu-noblotting
    • Fulcher, C. A., S. de Graaf Mahoney, and T. S. Zimmerman. 1987. Factor VIII inhibitor IgG subclass and FVIII polypeptide specificity determined by immu-noblotting. Blood 69: 1475-1480.
    • (1987) Blood , vol.69 , pp. 1475-1480
    • Fulcher, C.A.1    de Graaf Mahoney, S.2    Zimmerman, T.S.3
  • 26
    • 0023685204 scopus 로고
    • Immunoblot analysis shows changes in FVIII inhibitor chain specificity in FVIII inhibitor patients over time
    • Fulcher, C. A., K. Lechner, and S. de Graaf Mahoney. 1988. Immunoblot analysis shows changes in FVIII inhibitor chain specificity in FVIII inhibitor patients over time. Blood 72: 1348-1356.
    • (1988) Blood , vol.72 , pp. 1348-1356
    • Fulcher, C.A.1    Lechner, K.2    de Graaf Mahoney, S.3
  • 27
    • 0035278835 scopus 로고    scopus 로고
    • In hemophilia a and autoantibody inhibitor patients: The factor viii a2 domain and light chain are most immunogenic
    • Scandella, D., H. Nakai, M. Felch, W. Mondorf, I. Scharrer, L. Hoyer, and E. Saenko. 2001. In hemophilia a and autoantibody inhibitor patients: the factor viii a2 domain and light chain are most immunogenic. Thromb. Res. 101: 377-385.
    • (2001) Thromb. Res , vol.101 , pp. 377-385
    • Scandella, D.1    Nakai, H.2    Felch, M.3    Mondorf, W.4    Scharrer, I.5    Hoyer, L.6    Saenko, E.7
  • 28
    • 0024328077 scopus 로고
    • Molecular basis of factor VIII inhibition by human antibodies: Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid
    • Arai, M., D. Scandella, and L. W. Hoyer. 1989. Molecular basis of factor VIII inhibition by human antibodies: antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid. J. Clin. Invest. 83: 1978-1984.
    • (1989) J. Clin. Invest , vol.83 , pp. 1978-1984
    • Arai, M.1    Scandella, D.2    Hoyer, L.W.3
  • 29
    • 0029861521 scopus 로고    scopus 로고
    • Slowed release of ihrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for FVIII inhibition
    • Saenko, E. L., M. Shima, G. E. Gilbert, and D. Scandella. 1996. Slowed release of ihrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for FVIII inhibition. J. Biol. Chem. 271: 27424-27431.
    • (1996) J. Biol. Chem , vol.271 , pp. 27424-27431
    • Saenko, E.L.1    Shima, M.2    Gilbert, G.E.3    Scandella, D.4
  • 30
    • 0027457180 scopus 로고
    • A factor VIII neutralizing monoclonal antibody and a human inhibitor alloantibody recognizing epitopes in the C2 domain inhibit factor VIII binding to von Willebrand factor and to phosphatidylserine
    • Shima, M., D. Scandella, A. Yoshioka, H. Nakai, I. Tanaka, S. Kamisue, S. Terada, and H. Fukui. 1993. A factor VIII neutralizing monoclonal antibody and a human inhibitor alloantibody recognizing epitopes in the C2 domain inhibit factor VIII binding to von Willebrand factor and to phosphatidylserine. Thromb. Haemostasis 69: 240-246.
    • (1993) Thromb. Haemostasis , vol.69 , pp. 240-246
    • Shima, M.1    Scandella, D.2    Yoshioka, A.3    Nakai, H.4    Tanaka, I.5    Kamisue, S.6    Terada, S.7    Fukui, H.8
  • 31
    • 0032127414 scopus 로고    scopus 로고
    • Some human inhibitor antibodies interfere with factor VIII binding to Factor IX
    • Zhong, D., E. L. Saenko, M. Shima, M. Felch, and D. Scandella. 1998. Some human inhibitor antibodies interfere with factor VIII binding to Factor IX. Blood 92: 136-142.
    • (1998) Blood , vol.92 , pp. 136-142
    • Zhong, D.1    Saenko, E.L.2    Shima, M.3    Felch, M.4    Scandella, D.5
  • 33
    • 0024504004 scopus 로고
    • Identification of a FVIII epitope recognized by a human hemophilic inhibitor
    • Lubahn, B. C, J. Ware, D. W. Stafford, and H. M. Reisner. 1989. Identification of a FVIII epitope recognized by a human hemophilic inhibitor. Blood 73: 497-499.
    • (1989) Blood , vol.73 , pp. 497-499
    • Lubahn, B.C.1    Ware, J.2    Stafford, D.W.3    Reisner, H.M.4
  • 34
    • 0030930805 scopus 로고    scopus 로고
    • The interplay between binding energy and catalysis in the evolution of a catalytic antibody
    • Ulrich, H., E. Mundorff, B. Santarsiero, E. Driggers, R. Stevens, and P. Schultz. 1997. The interplay between binding energy and catalysis in the evolution of a catalytic antibody. Nature 389: 271-275.
    • (1997) Nature , vol.389 , pp. 271-275
    • Ulrich, H.1    Mundorff, E.2    Santarsiero, B.3    Driggers, E.4    Stevens, R.5    Schultz, P.6
  • 35
    • 0032549776 scopus 로고    scopus 로고
    • Immuno-logical origins of binding and catalysis in a Diels-Alderase antibody
    • Romesberg, F. E., B. Spiller, P. G. Schultz, and R. C. Stevens. 1998. Immuno-logical origins of binding and catalysis in a Diels-Alderase antibody. Science 279: 1929-1933.
    • (1998) Science , vol.279 , pp. 1929-1933
    • Romesberg, F.E.1    Spiller, B.2    Schultz, P.G.3    Stevens, R.C.4
  • 36
    • 0033579299 scopus 로고    scopus 로고
    • Evolution of shape complementarity and catalytic efficiency from a primordial antibody template
    • Xu, J., Q. Deng, J. Chen, K. N. Houk, J. Bartek, D. Hilvert, and I. A. Wilson. 1999. Evolution of shape complementarity and catalytic efficiency from a primordial antibody template. Science 286: 2345-2348.
    • (1999) Science , vol.286 , pp. 2345-2348
    • Xu, J.1    Deng, Q.2    Chen, J.3    Houk, K.N.4    Bartek, J.5    Hilvert, D.6    Wilson, I.A.7
  • 38
    • 0033507846 scopus 로고    scopus 로고
    • Innate antibody catalysis
    • Gololobov, G., M. Sun, and S. Paul. 1999. Innate antibody catalysis. Mol. Immunol. 36: 1215-1222.
    • (1999) Mol. Immunol , vol.36 , pp. 1215-1222
    • Gololobov, G.1    Sun, M.2    Paul, S.3
  • 39
    • 0037805717 scopus 로고    scopus 로고
    • Broadly distributed chemical reactivity of natural antibodies expressed in coordination with specific antigen binding activity
    • Planque, S., H. Taguchi, G. Burr, G. Bhatia, S. Karle, Y. X. Zhou, Y. Nishiyama, and S. Paul. 2003. Broadly distributed chemical reactivity of natural antibodies expressed in coordination with specific antigen binding activity. J. Biol. Chem. 278: 20436-20443.
    • (2003) J. Biol. Chem , vol.278 , pp. 20436-20443
    • Planque, S.1    Taguchi, H.2    Burr, G.3    Bhatia, G.4    Karle, S.5    Zhou, Y.X.6    Nishiyama, Y.7    Paul, S.8
  • 41
    • 0032877833 scopus 로고    scopus 로고
    • A possible role of catalytic antibodies in metabolism
    • Friboulet, A., B. Avalle, H. Debat, and D. Thomas. 1999. A possible role of catalytic antibodies in metabolism. Immunol. Today 20: 474-475.
    • (1999) Immunol. Today , vol.20 , pp. 474-475
    • Friboulet, A.1    Avalle, B.2    Debat, H.3    Thomas, D.4
  • 42
    • 0028910170 scopus 로고
    • Unexpectedly high occurence of catalytic antibodies in MLR/lpr and SLJ mice immunized with a transition-state analog: Is there a linkage to autoimmunity
    • Tawfik, D. S., R. Chap, B. S. Green, M. Sela, and Z. Eshhar. 1995. Unexpectedly high occurence of catalytic antibodies in MLR/lpr and SLJ mice immunized with a transition-state analog: is there a linkage to autoimmunity. Proc. Natl. Acad. Sci. USA 92: 2145-2149.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2145-2149
    • Tawfik, D.S.1    Chap, R.2    Green, B.S.3    Sela, M.4    Eshhar, Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.