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Volumn 298, Issue 1-2, 2009, Pages 101-110

An assessment of organ and intestinal histomorphology and cellular stress response in Atlantic salmon (Salmo salar L.) fed genetically modified Roundup Ready® soy

Author keywords

Atlantic salmon; Genetic modification; Intestine; Roundup Ready soy; Stress

Indexed keywords

AQUACULTURE PRODUCTION; DIET; ENVIRONMENTAL STRESS; GENETICALLY MODIFIED ORGANISM; HEMATOLOGY; MORPHOLOGY; SALMONID; SOYBEAN;

EID: 70450222697     PISSN: 00448486     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquaculture.2009.10.011     Document Type: Article
Times cited : (20)

References (67)
  • 2
    • 3442876969 scopus 로고    scopus 로고
    • Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets
    • Andersen C.L., Jensen J.L., and Orntoft T.F. Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. Cancer Res. 64 (2004) 5245-5250
    • (2004) Cancer Res. , vol.64 , pp. 5245-5250
    • Andersen, C.L.1    Jensen, J.L.2    Orntoft, T.F.3
  • 3
    • 0030498208 scopus 로고    scopus 로고
    • Development and regression of soybean meal induced enteritis in Atlantic salmon, Salmo salar L., distal intestine: a comparison with the intestines of fasted fish
    • Baeverfjord G., and Krogdahl Å. Development and regression of soybean meal induced enteritis in Atlantic salmon, Salmo salar L., distal intestine: a comparison with the intestines of fasted fish. J. Fish Dis. 19 (1996) 375-387
    • (1996) J. Fish Dis. , vol.19 , pp. 375-387
    • Baeverfjord, G.1    Krogdahl, Å.2
  • 4
    • 33750621545 scopus 로고    scopus 로고
    • Effects of dietary soybean meal and photoperiod cycle on osmoregulation following seawater exposure in Atlantic salmon smolts
    • Bakke-McKellep A.M., Refstie S., Stefansson S.O., Vanthanouvong V., Hemre G.-I., and Kroghdahl Å. Effects of dietary soybean meal and photoperiod cycle on osmoregulation following seawater exposure in Atlantic salmon smolts. J. Fish Biol. 69 (2006) 1396-1426
    • (2006) J. Fish Biol. , vol.69 , pp. 1396-1426
    • Bakke-McKellep, A.M.1    Refstie, S.2    Stefansson, S.O.3    Vanthanouvong, V.4    Hemre, G.-I.5    Kroghdahl, Å.6
  • 5
    • 33846325928 scopus 로고    scopus 로고
    • Effects of dietary soyabean meal, inulin and oxytetracycline on intestinal microbiota and epithelial cell stress, apoptosis and proliferation in the teleost Atlantic salmon (Salmo salar L.)
    • Bakke-McKellep A.M., Penn M.H., Salas P.M., Refstie S., Sperstad S., Landsverk T., Ringo E., and Krogdahl Å. Effects of dietary soyabean meal, inulin and oxytetracycline on intestinal microbiota and epithelial cell stress, apoptosis and proliferation in the teleost Atlantic salmon (Salmo salar L.). Br. J. Nutr. 97 (2007) 699-713
    • (2007) Br. J. Nutr. , vol.97 , pp. 699-713
    • Bakke-McKellep, A.M.1    Penn, M.H.2    Salas, P.M.3    Refstie, S.4    Sperstad, S.5    Landsverk, T.6    Ringo, E.7    Krogdahl, Å.8
  • 6
    • 0003004587 scopus 로고
    • Physiological changes in fish from stress in aquaculture with emphasis on the response and effects of corticosteroids
    • Barton B.A., and Iwama G.K. Physiological changes in fish from stress in aquaculture with emphasis on the response and effects of corticosteroids. Annu. Rev. Fish Dis. 1 (1991) 3-26
    • (1991) Annu. Rev. Fish Dis. , vol.1 , pp. 3-26
    • Barton, B.A.1    Iwama, G.K.2
  • 8
    • 36949003025 scopus 로고    scopus 로고
    • Identification of a transcriptional fingerprint of estrogen exposure in rainbow trout liver
    • Benninghoff A.D., and Williams D.E. Identification of a transcriptional fingerprint of estrogen exposure in rainbow trout liver. Toxicol. Sci. 101 (2008) 65-80
    • (2008) Toxicol. Sci. , vol.101 , pp. 65-80
    • Benninghoff, A.D.1    Williams, D.E.2
  • 10
    • 35948929057 scopus 로고    scopus 로고
    • Toxicity studies of genetically modified plants: a review of the published literature
    • Domingo J.L. Toxicity studies of genetically modified plants: a review of the published literature. Crit. Rev. Food Sci. Nutr. 47 (2007) 721-733
    • (2007) Crit. Rev. Food Sci. Nutr. , vol.47 , pp. 721-733
    • Domingo, J.L.1
  • 11
    • 70450222164 scopus 로고    scopus 로고
    • EFSA, 2006. Guidance document of the Scientific Panel on Genetically Modified Organisms for the risk assessment of genetically modified plants and derived food and feed. in: EFSA (Ed.). The EFSA Journal, pp. 1-100.
    • EFSA, 2006. Guidance document of the Scientific Panel on Genetically Modified Organisms for the risk assessment of genetically modified plants and derived food and feed. in: EFSA (Ed.). The EFSA Journal, pp. 1-100.
  • 12
    • 84863681578 scopus 로고    scopus 로고
    • Report of the EFSA GMO Panel Working Group on Animal Feeding Trials: safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials
    • EFSA
    • EFSA. Report of the EFSA GMO Panel Working Group on Animal Feeding Trials: safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials. Food Chem. Toxicol. 46 (2008) 1-70
    • (2008) Food Chem. Toxicol. , vol.46 , pp. 1-70
  • 13
    • 15944366903 scopus 로고    scopus 로고
    • No apparent differences in intestinal histology of channel catfish (Ictalurus punctatus) fed heat-treated and non-heat-treated raw soybean meal
    • Evans J.J., Pasnik D.J., Peres H., Lim C., and Klesius P.H. No apparent differences in intestinal histology of channel catfish (Ictalurus punctatus) fed heat-treated and non-heat-treated raw soybean meal. Aqua Nutr. 11 (2005) 123-129
    • (2005) Aqua Nutr. , vol.11 , pp. 123-129
    • Evans, J.J.1    Pasnik, D.J.2    Peres, H.3    Lim, C.4    Klesius, P.H.5
  • 14
    • 0033057848 scopus 로고    scopus 로고
    • Heat shock proteins, molecular chaperons, and the stress response: evolutionary and ecological physiology
    • Feder M.E., and Hofmann G.E. Heat shock proteins, molecular chaperons, and the stress response: evolutionary and ecological physiology. Annu. Rev. Physiol. 61 (1999) 243-282
    • (1999) Annu. Rev. Physiol. , vol.61 , pp. 243-282
    • Feder, M.E.1    Hofmann, G.E.2
  • 16
    • 33845547781 scopus 로고    scopus 로고
    • Studies on feeds from genetically modified plants (GMP)-contributions to nutritional and safety assessment
    • Flachowsky G., Aulrich K., Böhme H., and Halle I. Studies on feeds from genetically modified plants (GMP)-contributions to nutritional and safety assessment. Anim. Feed Sci. Technol. 133 (2007) 2-30
    • (2007) Anim. Feed Sci. Technol. , vol.133 , pp. 2-30
    • Flachowsky, G.1    Aulrich, K.2    Böhme, H.3    Halle, I.4
  • 17
    • 0033048638 scopus 로고    scopus 로고
    • On the path to the heat shock response: destabilization and formation of partially folded protein intermediates, a consequence of protein thiol modifications
    • Freeman M.E., Borrelli M.J., Meredith M.J., and Lepock J.R. On the path to the heat shock response: destabilization and formation of partially folded protein intermediates, a consequence of protein thiol modifications. Free Radic. Biol. Med. 26 (1999) 737-745
    • (1999) Free Radic. Biol. Med. , vol.26 , pp. 737-745
    • Freeman, M.E.1    Borrelli, M.J.2    Meredith, M.J.3    Lepock, J.R.4
  • 20
    • 38249027684 scopus 로고
    • The effect of fin-clipping on growth rate survival and sexual maturity of rainbow trout
    • Gjerde B., and Refstie T. The effect of fin-clipping on growth rate survival and sexual maturity of rainbow trout. Aquaculture 73 (1988) 383-389
    • (1988) Aquaculture , vol.73 , pp. 383-389
    • Gjerde, B.1    Refstie, T.2
  • 21
    • 0027184721 scopus 로고
    • Molecular chaperone functions of heat shock proteins
    • Hendrick J.P., and Hartl F.U. Molecular chaperone functions of heat shock proteins. Annu. Rev. Biochem. 62 (1993) 349-384
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 349-384
    • Hendrick, J.P.1    Hartl, F.U.2
  • 23
    • 15744381713 scopus 로고
    • Kinetic PCR analysis: real-time monitoring of DNA amplification reactions
    • Higuchi R., Fockler C., Dollinger G., and Watson R. Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Nat. Biotech. 11 (1993) 1026-1030
    • (1993) Nat. Biotech. , vol.11 , pp. 1026-1030
    • Higuchi, R.1    Fockler, C.2    Dollinger, G.3    Watson, R.4
  • 28
    • 0031793127 scopus 로고    scopus 로고
    • Heat shock proteins 70 kDa: molecular biology, biochemistry and physiology
    • Kiang J.G., and Tsokos G.C. Heat shock proteins 70 kDa: molecular biology, biochemistry and physiology. Pharmacol. Ther. 80 (1998) 183-201
    • (1998) Pharmacol. Ther. , vol.80 , pp. 183-201
    • Kiang, J.G.1    Tsokos, G.C.2
  • 29
    • 24044493523 scopus 로고    scopus 로고
    • Fasting and refeeding cause rapid changes in intestinal tissue mass and digestive enzyme capacities of Atlantic salmon (Salmo salar L.)
    • Krogdahl Å., and Bakke-McKellep A.M. Fasting and refeeding cause rapid changes in intestinal tissue mass and digestive enzyme capacities of Atlantic salmon (Salmo salar L.). Comp. Biochem. Physiol. A Mol. Integr. Physiol. 141 (2005) 450-460
    • (2005) Comp. Biochem. Physiol. A Mol. Integr. Physiol. , vol.141 , pp. 450-460
    • Krogdahl, Å.1    Bakke-McKellep, A.M.2
  • 30
    • 0037828816 scopus 로고    scopus 로고
    • The scientific basis for risk assessment and regulation of genetically modified foods
    • Kuiper H.A., and Kleter G.A. The scientific basis for risk assessment and regulation of genetically modified foods. Trends Food Sci. Technol. 14 (2003) 277-293
    • (2003) Trends Food Sci. Technol. , vol.14 , pp. 277-293
    • Kuiper, H.A.1    Kleter, G.A.2
  • 31
  • 32
    • 0030764256 scopus 로고    scopus 로고
    • hsp47 and hsp70 gene expression is differentially regulated in a stress- and tissue specific manner in zebrafish embryos
    • Lele Z., Engel S., and Krone P.H. hsp47 and hsp70 gene expression is differentially regulated in a stress- and tissue specific manner in zebrafish embryos. Dev. Genet. 21 (1997) 123-133
    • (1997) Dev. Genet. , vol.21 , pp. 123-133
    • Lele, Z.1    Engel, S.2    Krone, P.H.3
  • 33
    • 0036704287 scopus 로고    scopus 로고
    • Ultrastructural morphometrical and immunocytochemical analyses of hepatocyte nuclei from mice fed on genetically modified soybean
    • Malatesta M., Caporaloni C., Gavaudan S., Rocchi M.B.L., Serafini S., Tiberi C., and Gazzanelli G. Ultrastructural morphometrical and immunocytochemical analyses of hepatocyte nuclei from mice fed on genetically modified soybean. Cell Struct. Funct. 27 (2002) 173-180
    • (2002) Cell Struct. Funct. , vol.27 , pp. 173-180
    • Malatesta, M.1    Caporaloni, C.2    Gavaudan, S.3    Rocchi, M.B.L.4    Serafini, S.5    Tiberi, C.6    Gazzanelli, G.7
  • 34
    • 0346789520 scopus 로고    scopus 로고
    • Fine structural analysis of pancreatic acinar cell nuclei from mice fed on genetically modified soybean
    • Malatesta M., Biggiogera M., Manuali E., Rocchi M.B., Baldelli B., and GAzzanelli G. Fine structural analysis of pancreatic acinar cell nuclei from mice fed on genetically modified soybean. Eur. J. Histochem. 47 (2003) 358-358
    • (2003) Eur. J. Histochem. , vol.47 , pp. 358-358
    • Malatesta, M.1    Biggiogera, M.2    Manuali, E.3    Rocchi, M.B.4    Baldelli, B.5    GAzzanelli, G.6
  • 35
  • 36
    • 85006851353 scopus 로고    scopus 로고
    • Hepatoma tissue culture (HTC) cells as a model for investigating the effects of low concentrations of herbicide on cell structure and function
    • Malatesta M., Perdoni F., Santin G., Battistelli S., Muller S., and Biggiogera M. Hepatoma tissue culture (HTC) cells as a model for investigating the effects of low concentrations of herbicide on cell structure and function. Toxicol. in Vitro 22 (2008) 1853-1860
    • (2008) Toxicol. in Vitro , vol.22 , pp. 1853-1860
    • Malatesta, M.1    Perdoni, F.2    Santin, G.3    Battistelli, S.4    Muller, S.5    Biggiogera, M.6
  • 40
    • 0026592050 scopus 로고
    • Transcriptional regulation of heat shock genes
    • Morimoto R.I., Sarge K.D., and Abravaya K. Transcriptional regulation of heat shock genes. J. Biol. Chem. 267 (1992) 21987-21990
    • (1992) J. Biol. Chem. , vol.267 , pp. 21987-21990
    • Morimoto, R.I.1    Sarge, K.D.2    Abravaya, K.3
  • 41
    • 0027246160 scopus 로고
    • Thyroid hormone deiodination in brain, liver, gill, heart and muscle of Atlantic salmon (Salmo salar) during photoperiodically-induced parr-smolt transformation, I. Outer- and inner-ring thyroxine deiodination
    • Morin P.P., Hara T.J., and Eales J.G. Thyroid hormone deiodination in brain, liver, gill, heart and muscle of Atlantic salmon (Salmo salar) during photoperiodically-induced parr-smolt transformation, I. Outer- and inner-ring thyroxine deiodination. Gen. Comp. Endocrinol. 90 (1993) 142-156
    • (1993) Gen. Comp. Endocrinol. , vol.90 , pp. 142-156
    • Morin, P.P.1    Hara, T.J.2    Eales, J.G.3
  • 42
    • 0034102446 scopus 로고    scopus 로고
    • Effects of soybean meal and salinity on intestinal transport of nutrients in Atlantic salmon (Salmo salar L.) and rainbow trout (Oncorhynchus mykiss)
    • Nordrum S., Bakke-McKellep A.M., Krogdahl Å., and Buddington R.K. Effects of soybean meal and salinity on intestinal transport of nutrients in Atlantic salmon (Salmo salar L.) and rainbow trout (Oncorhynchus mykiss). Comp. Biochem. Physiol. B Biochem. Mol. Biol. 125 (2000) 317-335
    • (2000) Comp. Biochem. Physiol. B Biochem. Mol. Biol. , vol.125 , pp. 317-335
    • Nordrum, S.1    Bakke-McKellep, A.M.2    Krogdahl, Å.3    Buddington, R.K.4
  • 43
    • 0141450636 scopus 로고    scopus 로고
    • Consensus Document on Compositional Considerations for New Varieties of Soybean: Key Food and Feed Nutrients and Anti-Nutrients
    • OECD, 2001. Consensus Document on Compositional Considerations for New Varieties of Soybean: Key Food and Feed Nutrients and Anti-Nutrients. Series on the safety of novel foods and feeds, No. 2. http://www.olis.oecd.org/olis/2001doc.nsf/LinkTo/NT00005036/$FILE /JT00117705.PDF.
    • (2001) Series on the safety of novel foods and feeds , vol.2
  • 44
    • 28344455318 scopus 로고    scopus 로고
    • Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon
    • Olsvik P., Lie K., Jordal A.-E., Nilsen T., and Hordvik I. Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon. BMC Mol. Biol. 6 (2005) 21
    • (2005) BMC Mol. Biol. , vol.6 , pp. 21
    • Olsvik, P.1    Lie, K.2    Jordal, A.-E.3    Nilsen, T.4    Hordvik, I.5
  • 45
    • 34347401798 scopus 로고    scopus 로고
    • Do anesthetics and sampling strategies affect transcription analysis of fish tissues?
    • Olsvik P., Lie K., and Hevrøy E. Do anesthetics and sampling strategies affect transcription analysis of fish tissues?. BMC Mol. Biol. 8 (2007) 48
    • (2007) BMC Mol. Biol. , vol.8 , pp. 48
    • Olsvik, P.1    Lie, K.2    Hevrøy, E.3
  • 46
    • 0036007576 scopus 로고    scopus 로고
    • Effects of four anaesthetics on the innate immune response of gilthead seabream (Sparus aurata L.)
    • Ortuño J., Esteban M.A., and Meseguer J. Effects of four anaesthetics on the innate immune response of gilthead seabream (Sparus aurata L.). Fish Shellfish Immunol. 12 (2002) 49-59
    • (2002) Fish Shellfish Immunol. , vol.12 , pp. 49-59
    • Ortuño, J.1    Esteban, M.A.2    Meseguer, J.3
  • 49
    • 0041921066 scopus 로고    scopus 로고
    • In vivo studies on possible health consequences of genetically modified ingredients consisting of genetically modified plants
    • Pryme I.F., and Lembcke R. In vivo studies on possible health consequences of genetically modified ingredients consisting of genetically modified plants. Nutr. Health 17 (2003) 1-8
    • (2003) Nutr. Health , vol.17 , pp. 1-8
    • Pryme, I.F.1    Lembcke, R.2
  • 51
    • 0029656230 scopus 로고    scopus 로고
    • Fish blood parameters as a potential tool for identification of stress caused by environmental factors and chemical intoxication
    • Roche H., and Bogé G. Fish blood parameters as a potential tool for identification of stress caused by environmental factors and chemical intoxication. Mar. Environ. Res. 41 (1996) 27-43
    • (1996) Mar. Environ. Res. , vol.41 , pp. 27-43
    • Roche, H.1    Bogé, G.2
  • 52
    • 55649090808 scopus 로고    scopus 로고
    • Organs development, gene expression and health of Atlantic salmon (Salmo salar L.) fed genetically modified soybeans compared to the near-isogenic non-modified parental line
    • Sagstad A., Sanden M., Krogdahl Å., Bakke-McKellep A.M., Frøystad M., and Hemre G.-I. Organs development, gene expression and health of Atlantic salmon (Salmo salar L.) fed genetically modified soybeans compared to the near-isogenic non-modified parental line. Aqua Nutr. 14 (2008) 556-572
    • (2008) Aqua Nutr. , vol.14 , pp. 556-572
    • Sagstad, A.1    Sanden, M.2    Krogdahl, Å.3    Bakke-McKellep, A.M.4    Frøystad, M.5    Hemre, G.-I.6
  • 53
    • 0000231740 scopus 로고
    • Normal ranges of some blood chemistry parameters in adult farmed Atlantic salmon, Salmo salar
    • Sandnes K., Lie Ø., and Waagbø R. Normal ranges of some blood chemistry parameters in adult farmed Atlantic salmon, Salmo salar. J. Fish Biol. 32 (1988) 129-136
    • (1988) J. Fish Biol. , vol.32 , pp. 129-136
    • Sandnes, K.1    Lie, Ø.2    Waagbø, R.3
  • 54
    • 34247253329 scopus 로고    scopus 로고
    • New analysis of a rat feeding study with a genetically modified maize reveals signs of hepatorenal toxicity
    • Séralini G.-E., Cellier D., and de Vendomois J. New analysis of a rat feeding study with a genetically modified maize reveals signs of hepatorenal toxicity. Arch. Environ. Contam. Toxicol. 52 (2007) 596-602
    • (2007) Arch. Environ. Contam. Toxicol. , vol.52 , pp. 596-602
    • Séralini, G.-E.1    Cellier, D.2    de Vendomois, J.3
  • 55
    • 67650272420 scopus 로고    scopus 로고
    • A long term trial with Atlantic salmon (Salmo salar L.) fed genetically modified soy; focusing general health and performance before, during and after the parr-smolt transformation
    • Sissener N.H., Sanden M., Bakke A.M., Kroghdahl Å., and Hemre G.I. A long term trial with Atlantic salmon (Salmo salar L.) fed genetically modified soy; focusing general health and performance before, during and after the parr-smolt transformation. Aquaculture (2009) 108-117
    • (2009) Aquaculture , pp. 108-117
    • Sissener, N.H.1    Sanden, M.2    Bakke, A.M.3    Kroghdahl, Å.4    Hemre, G.I.5
  • 56
    • 77953022054 scopus 로고    scopus 로고
    • Proteomic profiling of liver from Atlantic salmon (Salmo salar) fed genetically modified soy compared to the near-isogenic non-GM line
    • doi:10.1007/s10126-009-9214-1
    • Sissener, N.H., Martin, S.A.M., Cash, P., Hevrøy, E.M., Sanden, M., Hemre, G.I., 2009. Proteomic profiling of liver from Atlantic salmon (Salmo salar) fed genetically modified soy compared to the near-isogenic non-GM line. Marine Biotechnol. doi:10.1007/s10126-009-9214-1.
    • (2009) Marine Biotechnol
    • Sissener, N.H.1    Martin, S.A.M.2    Cash, P.3    Hevrøy, E.M.4    Sanden, M.5    Hemre, G.I.6
  • 57
    • 1842664385 scopus 로고    scopus 로고
    • Transgene integration in plants: poking or patching holes in promiscuous genomes?
    • Somers D.A., and Makarevitch I. Transgene integration in plants: poking or patching holes in promiscuous genomes?. Curr. Opin. Biotechnol. 15 (2004) 126-131
    • (2004) Curr. Opin. Biotechnol. , vol.15 , pp. 126-131
    • Somers, D.A.1    Makarevitch, I.2
  • 58
    • 0036837529 scopus 로고    scopus 로고
    • Effects of redox cycling compounds on glutathione content and activity of glutathione-related enzymes in rainbow trout liver
    • Stephensen E., Sturve J., and Forlin L. Effects of redox cycling compounds on glutathione content and activity of glutathione-related enzymes in rainbow trout liver. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 133 (2002) 435-442
    • (2002) Comp. Biochem. Physiol. C Toxicol. Pharmacol. , vol.133 , pp. 435-442
    • Stephensen, E.1    Sturve, J.2    Forlin, L.3
  • 60
    • 36549040052 scopus 로고    scopus 로고
    • Beta-Naphthoflavone and benzo(a)pyrene treatment affect liver intermediary metabolism and plasma cortisol levels in rainbow trout Oncorhynchus mykiss
    • Tintos A., Gesto M., Míguez J.M., and Soengas J.L. Beta-Naphthoflavone and benzo(a)pyrene treatment affect liver intermediary metabolism and plasma cortisol levels in rainbow trout Oncorhynchus mykiss. Ecotoxicol. Environ. Saf. 69 (2008) 180-186
    • (2008) Ecotoxicol. Environ. Saf. , vol.69 , pp. 180-186
    • Tintos, A.1    Gesto, M.2    Míguez, J.M.3    Soengas, J.L.4
  • 64
    • 0001499244 scopus 로고
    • Effects of soybean-containing diets on the proximal and distal intestine in Atlantic salmon (Salmo salar): a morphological study
    • Van den Ingh T.S.G.A.M., Krogdahl Å., Olli J.J., Hendriks H.G.C.J.M., and Koninkx J.G.J.F. Effects of soybean-containing diets on the proximal and distal intestine in Atlantic salmon (Salmo salar): a morphological study. Aquaculture 94 (1991) 297-305
    • (1991) Aquaculture , vol.94 , pp. 297-305
    • Van den Ingh, T.S.G.A.M.1    Krogdahl, Å.2    Olli, J.J.3    Hendriks, H.G.C.J.M.4    Koninkx, J.G.J.F.5
  • 65
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • 0034.0031-0034.0011
    • Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., and Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 3 (2002) 0034.0031-0034.0011
    • (2002) Genome Biol. , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 67
    • 0027420158 scopus 로고
    • How cells respond to stress
    • Welch W.J. How cells respond to stress. Sci. America 269 (1993) 56-64
    • (1993) Sci. America , vol.269 , pp. 56-64
    • Welch, W.J.1


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