Cytochrome c oxidase isoform IV-2 is involved in 3-nitropropionic acid-induced toxicity in striatal astrocytes

GLIA

Volumn 57, Issue 14, 2009, Pages 1480-1491

  Shilpee, Singh ^a   Magdalena, Misiak ^a   Cordian, Beyer ^a   Susanne, Arnold ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Astroglia; Mitochondria; Reactive oxygen species; Striatum

Indexed keywords

3 NITROPROPIONIC ACID; CYTOCHROME C OXIDASE; CYTOCHROME C OXIDASE IV 2; PEROXIDE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN MITOCHONDRION; CELL STRESS; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; HUNTINGTON CHOREA; IN VITRO STUDY; MOUSE; NERVE CELL NECROSIS; NEUROTOXICITY; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; UPREGULATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ASTROCYTES; CELL SURVIVAL; CELLS, CULTURED; CORPUS STRIATUM; ELECTRON TRANSPORT COMPLEX IV; HUNTINGTON DISEASE; ISOENZYMES; MICE; MICE, INBRED BALB C; MITOCHONDRIA; NECROSIS; NEUROTOXINS; NITRO COMPOUNDS; OXIDATIVE STRESS; PEROXIDES; PROPIONIC ACIDS; RNA, SMALL INTERFERING;

EID: 70450220248     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20864     Document Type: Article

References (42)

1. Arnold S, Kadenbach B. 1997. Cell respiration is controlled by ATP, an allosteric inhibitor of cytochrome-c oxidase. Eur J Biochem 249:350-354. (Pubitemid 27432632)
2. Arnold S, Kadenbach B. 1999. The intramitochondrial ATP/ADP-ratio controls cytochrome c oxidase activity allosterically. FEBS Lett 443:105-108. (Pubitemid 29078611)
3. Arnold S, Goglia F, Kadenbach B. 1998. 3,5-Diiodothyronine binds to subunit Va of cytochrome-c oxidase and abolishes the allosteric inhibition of respiration by ATP. Eur J Biochem 252:325-330. (Pubitemid 28102010)
4. Ayala A, Venero JL, Cano J, Machado A. 2007. Mitochondrial toxins and neurodegenerative diseases. Front Biosci 12:986-1007.
5. Barres BA. 1991. New roles for glia. J Neurosci 11:3685-3694.
6. Beal MF. 2005. Mitochondria take center stage in aging and neurodegeneration. Ann Neurol 58:495-505. (Pubitemid 41377212)
7. Brouillet E, Condé F, Beal MF. 1999. Hantraye P Replicating Huntington's disease phenotype in experimental animals. Prog Neurobiol 59:427-468. (Pubitemid 29392967)
8. Browne SE, Bowling AC, MacGarvey U, Baik MJ, Berger SC, Muqit MM, Bird ED, Beal MF. 1997. Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia. Ann Neurol 41:646-653. (Pubitemid 27212659)
9. Cadenas E, Boveris A, Ragan CI, Stoppani AO. 1977. Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria. Arch Biochem Biophys 180:248-257. (Pubitemid 8115490)
10. De Keyser J, Mostert JP, Koch MW. 2008. Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders. J Neurol Sci 267:3-16. (Pubitemid 351248899)
11. de la Monte SM, Vonsattel JP, Richardson EP Jr. 1988. Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease. J Neuropathol Exp Neurol 47:516-525.
12. Dröse S, Brandt U. 2008. The mechanism of mitochondrial superoxide production by cytochrome bc1 complex. J Biol Chem 283:21649-21654.
13. Dugan LL, Bruno VMG, Amagasu SM, Giffard RG. 1995. Glia modulate the response of murine cortical neurons to excitotoxicity: Glia exacerbate AMPA neurotoxicity. J Neurosci 15:4545-4555.
14. Esfandiari A, Soifiyoudine D, Paturneau-Jouas M. 1997. Inhibition of fatty acid beta-oxidation in rat brain cultured astrocytes exposed to the neurotoxin 3-nitropropionic acid. Dev Neurosci 19:312-320. (Pubitemid 27252655)
15. Ferrante RJ, Kowall NW, Beal MF, Martin JB, Bird ED, Richardson EP Jr. 1987. Morphologic and histochemical characteristics of a spared subset of striatal neurons in Huntington's disease. J Neuropathol Exp Neurol 46:12-27.
16. Geddes JW, Bondada V, Pang Z. 2000. Mechanism of 3-nitroproprionic acid neurotoxicity. In: Sandberg PR, Nishino H, Borlongan CV, editors. Mitochondrial inhibitors and neurodegenerative disorders. Totowa, NJ: Humana Press. pp 107-120.
17. 2+ in transgenic huntington disease rats. J Biol Chem 283:30715-30724.
18. Giaume C, Kirchhoff F, Matute C, Reichenbach A, Verkhratsky A. 2007. Glia: The fulcrum of brain diseases. Cell Death Differ 14:1324-1335.
19. Grossman LI, Lomax MI. 1997. Nuclear genes for cytochrome c oxidase. Biochim Biophys Acta 1352:174-192.
20. Gu M, Gash MT, Mann VM, Javoy-Agid F, Cooper JM, Schapira AH. 1996. Mitochondrial defect in Huntington's disease caudate nucleus. Ann Neurol 39:385-389. (Pubitemid 26100764)
21. Horvat S, Beyer C, Arnold S. 2006. Effect of hypoxia on the transcription pattern of subunit isoforms and the kinetics of cytochrome c oxidase in cortical astrocytes and cerebellar neurons. J Neurochem 99:937-951. (Pubitemid 44583451)
22. Hüttemann M, Kadenbach B, Grossman LI. 2001. Mammalian subunit IV isoforms of cytochrome c oxidase. Gene (Amst) 267:111-123. (Pubitemid 32304535)
23. Jenkins BG, Rosas HD, Chen YC, Makabe T, Myers R, Mac-Donald M, Rosen BR, Beal MF, Koroshetz WJ. 1998. 1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers. Neurology 50:1357-1365. (Pubitemid 28240352)
24. Jourdain P, Bergersen LH, Bhaukaurally K, Bezzi P, Santello M, Domercq M, Matute C, Tonello F, Gundersen V, Volterra A. 2007. Glutamate exocytosis from astrocytes controls synaptic strength. Nat Neurosci 10:331-339. (Pubitemid 46310468)
25. Kadenbach B, Arnold S, Lee I, Huttemann M. 2004. The possible role of cytochrome c oxidase in stress-induced apoptosis and degenerative diseases. Biochim Biophys Acta 1655:400-408. (Pubitemid 38526204)
26. Kadenbach B, H€uttemann M, Arnold S, Lee I, Bender E. 2000. Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase. Free Radic Biol Med 29:211-221. (Pubitemid 30734904)
27. Kipp M, Karakaya S, Pawlak J, Araujo-Wright G, Arnold S, Beyer C. 2006. Estrogen and the development and protection of nigrostriatal dopaminergic neurons: Concerted action of a multitude of signals, protective molecules, and growth factors. Front Neuroendocrinol 27:376-390. (Pubitemid 44738014)
28. Koroshetz WJ, Jenkins BG, Rosen BR, Beal MF. 1997. Energy metabolism defects in Huntington's disease and effects of coenzyme Q10. Ann Neurol 41:160-165. (Pubitemid 27082096)
29. Lee I, Bender E, Arnold S, Kadenbach B. 2001. New control of mitochondrial membrane potential and ROS formation - a hypothesis. Biol Chem 382:1629-1636. (Pubitemid 34100594)
30. Maragakis NJ, Rothstein JD. 2006. Mechanisms of disease: astrocytes in neurodegenerative disease. Nat Clin Pract Neurol 2:679-689.
31. Nishino H, Shimano Y, Kumazaki M, Sakurai T. 1995. Chronically administered 3-nitropropionic acid induces striatal lesion attributed to dysfunction of the blood-brain barrier. Neurosci Lett 186:161-164.
32. Panov AV, Gutekunst CA, Leavitt BR, Hayden MR, Burke JR, Strittmatter WJ, Greenamyre JT. 2002. Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. Nat Neurosci 5:731-736.
33. Pellerin L, Bouzier-Sore AK, Aubert A, Serres S, Merle M, Costalat R, Magistretti PJ. 2007. Activity-dependent regulation of energy metabolism by astrocytes: an update. Glia 55:1251-1262. (Pubitemid 47235366)
34. Rahman B, Kussmaul L, Hamprecht B, Dringen R. 2000. Glycogen is mobilized during the disposal of peroxides by cultured astroglial cells from rat brain. Neurosci Lett 290:169-172. (Pubitemid 30645859)
35. Ramaswamy S, McBride JL, Kordower JH. 2007. Animal models of Huntington's disease. ILAR J 48:356-373.
36. Sawa A, Tomoda T, Bae BI. 2003. Mechanisms of neuronal cell death in Huntington's disease. Cytogenet Genome Res 100:287-295. (Pubitemid 37467816)
37. Sawa A, Wiegand GW, Cooper J, Margolis RL, Sharp AH, Lawler JF Jr, Greenamyre JT, Snyder SH, Ross CA. 1999. Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization. Nat Med 5:1194-1198. (Pubitemid 29474426)
38. Schapira AH. 1997. Mitochondrial function in Huntington's disease: Clues for pathogenesis and prospects for treatment. Ann Neurol 41:141-142.
39. Tabrizi SJ, Cleeter MW, Xuereb J, Taanman JW, Cooper JM, Schapira AH. 1999. Biochemical abnormalities and excitotoxicity in Huntington's disease brain. Ann Neurol 45:25-32. (Pubitemid 29036428)
40. van Beek-Harmsen BJ, van der Laarse WJ. 2005. Immunohistochemical determination of cytosolic cytochrome C concentration in cardiomyocytes. J Histochem Cytochem 53:803-807.
41. Vis JC, Verbeek MM, De Waal RM, Ten Donkelaar HJ, Kremer HP. 1999. 3-Nitropropionic acid induces a spectrum of Huntington's disease-like neuropathology in rat striatum. Neuropathol Appl Neurobiol 25:513-521.
42. Wiesinger H, Hamprecht B, Dringen R. 1997. Metabolic pathways for glucose in astrocytes. Glia 21:22-34.