Elucidating the exact role of engineered CRABPII residues for the formation of a retinal protonated Schiff base

Proteins: Structure, Function and Bioinformatics

Volumn 77, Issue 4, 2009, Pages 812-822

  Vasileiou, Chrysoula ^a   Wang, Wenjing ^a   Jia, Xiaofei ^a   Sing, Kin ^a   Lee, Stephen ^a   Watson, Camille T ^a   Geiger, James H ^a   Borhan, Babak ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

B rgi Dunitz angle; Cellular retinoic acid binding protein; Ordered water network; Rhodopsin protein mimic; Schiff base

Indexed keywords

ARGININE; CELLULAR RETINOIC ACID BINDING PROTEIN 2; GLUTAMINE; IMINE; LYSINE; RETINAL; RETINOIC ACID BINDING PROTEIN; SCHIFF BASE; THREONINE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTON TRANSPORT; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; ARGININE; BASE SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN ENGINEERING; PROTONS; RECEPTORS, RETINOIC ACID; RECOMBINANT PROTEINS; RETINALDEHYDE; SCHIFF BASES; SPECTROMETRY, FLUORESCENCE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STATIC ELECTRICITY; TRYPTOPHAN; TYROSINE;

EID: 70450085594     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22495     Document Type: Article

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