Does smoking reduce the risk of Parkinson's disease through stimulation of the ubiquitin-proteasome system?

Medical Hypotheses

Volumn 73, Issue 6, 2009, Pages 887-891

  Chapman, Mary Ann ^a  

^a Visage Communications Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINE; NICOTINIC RECEPTOR; PROTEASOME; UBIQUITIN;

ARTICLE; CELL DEATH; DISEASE ASSOCIATION; FEEDBACK SYSTEM; HUMAN; HYPOTHESIS; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN FUNCTION; RISK FACTOR; RISK REDUCTION; SMOKING; UPREGULATION;

HUMANS; MODELS, THEORETICAL; PARKINSON DISEASE; PROTEASOME ENDOPEPTIDASE COMPLEX; RISK FACTORS; SMOKING; UBIQUITIN;

ANIMALIA;

EID: 70449730925     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2009.03.053     Document Type: Article

References (36)

1. Jankovic J. Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry 79 4 (2008) 368-376
2. Smith Y., Bevan M.D., Shink E., and Bolam J.P. Microcircuitry of the direct and indirect pathways of the basal ganglia. Neuroscience 86 2 (1998) 353-387
3. Braak H., Ghebremedhin E., Rub U., Bratzke H., and Del Tredici K. Stages in the development of Parkinson's disease-related pathology. Cell Tissue Res 318 1 (2004) 121-134
4. Brooks D.J. Imaging non-dopaminergic function in Parkinson's disease. Mol Imaging Biol 9 4 (2007) 217-222
5. Litvan I., Halliday G., Hallett M., et al. The etiopathogenesis of Parkinson disease and suggestions for future research. Part I. J Neuropathol Exp Neurol 66 4 (2007) 251-257
6. Hancock D.B., Martin E.R., Mayhew G.M., et al. Pesticide exposure and risk of Parkinson's disease: a family-based case-control study. BMC Neurol 8 6 (2008) 10.1186/1471-2377-8-6
7. Tanner C.M., and Goldman S.M. Epidemiology of Parkinson's disease. Neurol Clin 14 2 (1996) 317-335
8. Fratiglioni L., and Wang H.X. Smoking and Parkinson's and Alzheimer's disease: review of the epidemiological studies. Behav Brain Res 113 1-2 (2000) 117-120
9. Ritz B., Ascherio A., Checkoway H., et al. Pooled analysis of tobacco use and risk of Parkinson disease. Arch Neurol 64 7 (2007) 990-997
10. Shimohama S. Nicotinic receptor-mediated neuroprotection in neurodegenerative disease models. Biol Pharm Bull 32 3 (2009) 332-336
11. Ward R.J., Lallemand F., de Witte P., and Dexter D.T. Neurochemical pathways involved in the protective effects of nicotine and ethanol in preventing the development of Parkinson's disease: potential targets for the development of new therapeutic agents. Prog Neurobiol 85 2 (2008) 135-147
12. Picciotto M.R., and Zoli M. Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease. Front Biosci 13 (2008) 492-504
13. Wanamaker C.P., Christianson J.C., and Green W.N. Regulation of nicotinic acetylcholine receptor assembly. Ann N Y Acad Sci 998 (2003) 66-80
14. Christianson J.C., and Green W.N. Regulation of nicotinic receptor expression by the ubiquitin-proteasome system. Embo J 23 21 (2004) 4156-4165
15. Lansbury Jr. P.T., and Brice A. Genetics of Parkinson's disease and biochemical studies of implicated gene products. Curr Opin Cell Biol 14 5 (2002) 653-660
16. Walsh H., Govind A.P., Mastro R., et al. Up-regulation of nicotinic receptors by nicotine varies with receptor subtype. J Biol Chem 283 10 (2008) 6022-6032
17. Even N., Cardona A., Soudant M., Corringer P.J., Changeux J.P., and Cloez-Tayarani I. Regional differential effects of chronic nicotine on brain alpha 4-containing and alpha 6-containing receptors. Neuroreport 19 15 (2008) 1545-1550
18. Perry D.C., Davila-Garcia M.I., Stockmeier C.A., and Kellar K.J. Increased nicotinic receptors in brains from smokers: membrane binding and autoradiography studies. J Pharmacol Exp Ther 289 3 (1999) 1545-1552
19. Mukhin A.G., Kimes A.S., Chefer S.I., et al. Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: a PET study with 2-18F-FA-85380. J Nucl Med 49 10 (2008) 1628-1635
20. Brody A.L. Functional brain imaging of tobacco use and dependence. J Psychiatr Res 40 5 (2006) 404-418
21. Ficklin M.B., Zhao S., and Feng G. Ubiquilin-1 regulates nicotine-induced up-regulation of neuronal nicotinic acetylcholine receptors. J Biol Chem 280 40 (2005) 34088-34095
22. Kane J.K., Konu O., Ma J.Z., and Li M.D. Nicotine coregulates multiple pathways involved in protein modification/degradation in rat brain. Brain Res Mol Brain Res 132 2 (2004) 181-191
23. Brody A.L., Mandelkern M.A., London E.D., et al. Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors. Arch Gen Psychiatry 63 8 (2006) 907-915
24. Szewczyk N.J., Hartman J.J., Barmada S.J., and Jacobson L.A. Genetic defects in acetylcholine signalling promote protein degradation in muscle cells of Caenorhabditis elegans. J Cell Sci 113 Pt 11 (2000) 2003-2010
25. Carolan B.J., Heguy A., Harvey B.G., Leopold P.L., Ferris B., and Crystal R.G. Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers. Cancer Res 66 22 (2006) 10729-10740
26. Chen G., Gharib T.G., Huang C.C., et al. Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors. Clin Cancer Res 8 7 (2002) 2298-2305
27. Plun-Favreau H., Gandhi S., Wood-Kaczmar A., Deas E., Yao Z., and Wood N.W. What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease?. Ann N Y Acad Sci 1147 (2008) 30-36
28. Moisoi N., Klupsch K., Fedele V., et al. Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response. Cell Death Differ 16 3 (2009) 449-464
29. Germain D. Ubiquitin-dependent and -independent mitochondrial protein quality controls: implications in ageing and neurodegenerative diseases. Mol Microbiol 70 6 (2008) 1334-1341
30. Dauer W., and Przedborski S. Parkinson's disease: mechanisms and models. Neuron 39 6 (2003) 889-909
31. McNaught K.S., Belizaire R., Isacson O., Jenner P., and Olanow C.W. Altered proteasomal function in sporadic Parkinson's disease. Exp Neurol 179 1 (2003) 38-46
32. Corti O., Hampe C., Darios F., Ibanez P., Ruberg M., and Brice A. Parkinson's disease: from causes to mechanisms. C R Biol 328 2 (2005) 131-142
33. Masliah E., Rockenstein E., Veinbergs I., et al. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science 287 5456 (2000) 1265-1269
34. Corringer P.J., Sallette J., and Changeux J.P. Nicotine enhances intracellular nicotinic receptor maturation: a novel mechanism of neural plasticity?. J Physiol Paris 99 2-3 (2006) 162-171
35. Sharma A., and Brody A.L. In vivo brain imaging of human exposure to nicotine and tobacco. Handb Exp Pharmacol 192 (2009) 145-171
36. Lim K.L. Ubiquitin-proteasome system dysfunction in Parkinson's disease: current evidence and controversies. Expert Rev Proteomics 4 6 (2007) 769-781