Synthesis and Anti-Hiv activity of 4'-modified cyclopentenyl pyrimidine C-nucleosides

Nucleosides, Nucleotides and Nucleic Acids

Volumn 28, Issue 4, 2009, Pages 303-314

  Liu, Lian Jin ^a   Hong, Joon Hee ^a  

^a Chosun University   (South Korea)

Author keywords

Antiviral agents; Cyclopentenyl C nucleoside; SN2 alkylation

Indexed keywords

2 [ 4 (TERT BUTYLDIMETHYLSILANYLOXYMETHYL) 4 METHYL CYCLOPENT 2 ENYL] 3 METHOXY ACRYLIC ACID ETHYL ESTER; 2 [ 4 (TERT BUTYLDIMETHYLSILANYLOXYMETHYL) 4 METHYL CYCLOPENT 2 ENYL]MALONIC ACID DIETHYL ESTER; 2 [ 4,4 BIS(TERT BUTYLDIMETHYLSILANYLOXYMETHYL)CYCLOPENT 2 ENYL] 3 METHOXY ACRYLIC ACID ETHYL ESTER; 2 [ 4,4 BIS(TERT BUTYLDIMETHYLSILANYLOXYMETHYL)CYCLOPENT 2 ENYL]MALONIC ACID DIETHYL ESTER; 4' MODIFIED CYCLOPENTENYL PYRIMIDINE C NUCLEOSIDE; 4,4 BIS(TERT BUTYLDIMETHYLSILANYLOXYMETHYL)CYCLOPENT 2 ENYL ACETIC ACID ESTER; 5 [ 4 (HYDROXYMETHYL) 4 METHYL CYCLOPENT 2 ENYL]ISOCYTOSINE; 5 [ 4 (TERT BUTYLDIMETHYLSILANYLOXYMETHYL) 4 METHYL CYCLOPENT 2 ENYL]ISOCYTOSINE; 5 [ 4,4 BIS(HYDROXYMETHYL)CYCLOPENT 2 ENYL]ISOCYTOSINE; 5 [ 4,4 BIS(HYDROXYMETHYL)CYCLOPENT 2 ENYL]URACIL; 5 [ 4,4 BIS(TERT BUTYLDIMETHYLSILANYLOXYMETHYL)CYCLOPENT 2 ENYL]ISOCYTOSINE; 5 [ 4,4 BIS(TERT BUTYLDIMETHYLSILANYLOXYMETHYL)CYCLOPENT 2 ENYL]URACIL; [ 4 (TERT BUTYLDIMETHYLSILANYLOXYMETHYL) 4 METHYL CYCLOPENT 2 ENYL]ACETIC ACID ETHYL ESTER; ACETIC ACID DERIVATIVE; ACRYLIC ACID DERIVATIVE; ANTIVIRUS AGENT; CARBON; CYTIDINE DERIVATIVE; CYTOSINE DERIVATIVE; GANCICLOVIR; KETONE DERIVATIVE; MALONIC ACID DERIVATIVE; MESYLIC ACID DERIVATIVE; METHANESULFONIC ACID 4(TERT BUTYLDIMETHYLSILANYLOXYMETHYL) 4 METHYL CYCLOPENT 2 ENYL ESTER; METHANESULFONIC ACID 4,4 BIS(TERT BUTYLDIMETHYLSILANYLOXYMETHYL)CYCLOPENT 2 ENYL ESTER; PYRIMIDINE NUCLEOSIDE DERIVATIVE; TIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; URACIL DERIVATIVE; ZIDOVUDINE;

ALKYLATION; ANTIVIRAL ACTIVITY; ARTICLE; CELL LINE; CHEMICAL BOND; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY;

ALKYLATION; ANTI-HIV AGENTS; CELL LINE; CELL SURVIVAL; CYCLOPENTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; HIV-1; HUMANS; MICROBIAL SENSITIVITY TESTS; PYRIMIDINE NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 70449659336     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770902946058     Document Type: Article

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