Stereoselective synthesis and antimicrobial activity of benzofuran-based (1E)-1-(piperidin-1-yl)-N2-arylamidrazones

European Journal of Medicinal Chemistry

Volumn 44, Issue 12, 2009, Pages 4985-4997

  Abdel Aziz, Hatem A ^a   Mekawey, Amal A I ^b  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b AL AZHAR UNIVERSITY   (Egypt)

Author keywords

Amidrazones; Antimicrobial activity; Benzofurans; Propanehydrazonoyl chlorides; Sterioselectivity; X ray crystallography

Indexed keywords

1 (PIPERIDIN 1 YL) 1 (PHENYLHYDRAZONO) 2 [(3 METHYLBENZOFURAN 2 OYL)HYDRAZONO] 4 PHENYLBUT 3 ENE; 1 (PIPERIDIN 1 YL) 1 [(4 BROMOPHENYL)HYDRAZONO] 2 [(3 METHYLBENZOFURAN 2 OYL)HYDRAZONO] 4 (4 CHLOROPHENYL)BUT 3 ENE; 1 (PIPERIDIN 1 YL) 1 [(4 NITROPHENYL)HYDRAZONO] 2 [(3 METHYLBENZOFURAN 2 OYL)HYDRAZONO]PROPANE; 1 (PIPERIDIN 1 YL) 1 [(NITROPHENYL)HYDRAZONO] 2 [(3 METHYLBENZOFURAN 2 OYL)HYDRAZONO] 4 PHENYLBUT 3 ENE; 1 (PIPERIDIN 1 YL) 1 PHENYLHYDRAZONO 2 [(3 METHYL BENZOFURAN 2 OYL)HYDRAZONO]PROPANE; 2 [[(3 METHYLBENZOFURAN 2 YL)CARBONYL]HYDRAZONO]N (4 BROMOPHENYL)PROPANEHYDRAZONOYL CHLORIDE; 2 [[(3 METHYLBENZOFURAN 2 YL)CARBONYL]HYDRAZONO]N (4 METHOXYPHENYL)PROPANEHYDRAZONYL CHLORIDE; 2 [[(3 METHYLBENZOFURAN 2 YL)CARBONYL]HYDRAZONO]N (4 NITROPHENYL)PROPANEHYDRAZONOYL CHLORIDE; 2 [[(3 METHYLBENZOFURAN 2 YL)CARBONYL]HYDRAZONO]N (4 TOLYL)PROPANEHYDRAZONOYL CHLORIDE; 2 [[(3 METHYLBENZOFURAN 2 YL)CARBONYL]HYDRAZONO]N PHENYLPROPANEHYDRAZONOYL CHLORIDE; 3 METHYL N' 1 METHYL 2 [(4 NITROPHENYL)HYRAZONO 2 (PHENYLSULFONYL)ETHYLIDENE] 1 BENZOFURAN 2 CARBOHYRAZIDE; 3 METHYL N'(3 PHENYLPROP 2 EN 1 YLIDENE) 1 BENZOFURAN 2 CARBOHYDRAZIDE; AMOXICILLIN; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; BENZOFURAN DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; CHLORIDE; GRISEOFULVIN; N HYDROXY 2 [[(3 METHYL 1 BENZOFURAN 2 YL)CARBONYL]HYDRAZONO]N'(4 NITROPHENYL)PROPANEHYDRAZONAMIDE; N'[ETHYLIDENE] 3 METHYL 1 BENZOFURAN 2 CARBOHYDRAZIDE; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; BACILLUS SUBTILIS; BACTERIAL GROWTH; CANDIDA ALBICANS; CHEMICAL INTERACTION; CHEMICAL MODIFICATION; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; FUNGUS GROWTH; GROWTH INHIBITION; HYDROGEN BOND; NONHUMAN; PSEUDOMONAS AERUGINOSA; SOLID STATE; STAPHYLOCOCCUS AUREUS; STEREOCHEMISTRY; SUBSTITUTION REACTION; X RAY ANALYSIS; X RAY DIFFRACTION;

AMIDES; ANTI-INFECTIVE AGENTS; ANTIFUNGAL AGENTS; BACTERIA; BENZOFURANS; CRYSTALLOGRAPHY, X-RAY; FUNGI; HUMANS; HYDRAZONES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PIPERIDINES; STEREOISOMERISM;

EID: 70449642410     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.09.002     Document Type: Article

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