Genetic disruption of the alternative splicing of drebrin gene impairs context-dependent fear learning in adulthood

Neuroscience

Volumn 165, Issue 1, 2010, Pages 138-150

  Kojima, N ^a,b   Hanamura, K ^a   Yamazaki, H ^a   Ikeda, T ^c   Itohara, S ^c   Shirao, T ^a,b  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

actin cytoskeleton; dendritic spine; fear conditioning; isoform conversion; synaptic plasticity

Indexed keywords

DREBRIN; DREBRIN A; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL BEHAVIOR; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CELL FRACTIONATION; CELLULAR DISTRIBUTION; CONDITIONING; CONTROLLED STUDY; CYTOSOL; EXON; FEAR; FEMALE; FORCED SWIMMING TEST; FREEZING; GENE DELETION; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; KNOCKOUT MOUSE; LEARNING; MAZE TEST; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNAPTOSOME; WESTERN BLOTTING; WILD TYPE;

ALTERNATIVE SPLICING; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; DIZOCILPINE MALEATE; FEAR; LEARNING; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; NEUROPEPTIDES; PROTEIN ISOFORMS;

EID: 70449632127     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.10.016     Document Type: Article

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