Differential inhibitory effects of inotilone on inflammatory mediators, inducible nitric oxide synthase and cyclooxygenase-2, in LPS-stimulated murine macrophage

Molecular Nutrition and Food Research

Volumn 53, Issue 11, 2009, Pages 1386-1395

  Kuo, Yu Ching ^a   Lai, Ching Shu ^b   Wang, Ju Ming ^c   Badmaev, Vladimir ^d   Nagabhushanam, Kalyanam ^d   Ho, Chi Tang ^a   Pan, Min Hsiung ^b  

^a RUTGERS UNIVERSITY   (United States)

^b NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d SABINSA CORPORATION   (United States)

Author keywords

CCAAT; Cyclooxygenase 2 (COX 2); Enhancer binding protein beta; Inducible NO synthase (iNOS); Inotilone; LPS

Indexed keywords

ANTIINFLAMMATORY AGENT; AUTACOID; CCAAT ENHANCER BINDING PROTEIN BETA; CYCLOOXYGENASE 2; FURAN DERIVATIVE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INOTILONE; LIPOPOLYSACCHARIDE; MACROLIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; NITRITE; PROSTAGLANDIN E2; PTGS2 PROTEIN, MOUSE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; MACROPHAGE; METABOLISM; MOUSE; PHOSPHORYLATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FURANS; I-KAPPA B PROTEINS; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROLIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION;

MURINAE;

EID: 70449567343     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200800583     Document Type: Article

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