DNA repair mechanisms in eukaryotes: Special focus in Entamoeba histolytica and related protozoan parasites

Infection, Genetics and Evolution

Volumn 9, Issue 6, 2009, Pages 1051-1056

  López Camarillo, César ^a   Lopez Casamichana, Mavil ^a   Weber, Christian ^b,c   Guillen, Nancy ^b,c   Orozco, Esther ^d   Marchat, Laurence A ^e  

^a UNIVERSIDAD AUTÓNOMA DE LA CIUDAD DE MÉXICO   (Mexico)

^b INSTITUT PASTEUR   (France)

^c INSERM   (France)

^d DEPARTAMENTO DE FÍSICA   (Mexico)

^e INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

cDNA microarrays; DNA damage; DNA repair machineries; Entamoeba histolytica; Genome sequence; Protozoan parasites

Indexed keywords

CYTOTOXIC AGENT; DNA; METHYLTRANSFERASE; NUCLEOTIDE; RAD52 PROTEIN;

CELL VIABILITY; DNA DAMAGE; DNA INTEGRATION; DNA MICROARRAY; DNA REPAIR; ENTAMOEBA HISTOLYTICA; EUKARYOTE; EUKARYOTIC CELL; EXCISION REPAIR; GENE SEQUENCE; GENETIC STABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; IMMUNE RESPONSE; MISMATCH REPAIR; NONHUMAN; PRIORITY JOURNAL; PROTOZOON; REVIEW; SURVIVAL;

ANIMALS; DNA; DNA DAMAGE; DNA REPAIR; ENTAMOEBA HISTOLYTICA; EUKARYOTA; GENETIC TECHNIQUES; GENOME, PROTOZOAN; HUMANS; PROTOZOAN INFECTIONS;

ENTAMOEBA HISTOLYTICA; EUKARYOTA; PROTOZOA;

EID: 70449561537     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meegid.2009.06.024     Document Type: Review

References (41)

1. Alexiadis V., Lusser A., and Kadonaga J.T. A conserved N-terminal motif in Rad54 is important for chromatin remodeling and homologous strand pairing. J. Biol. Chem. 279 (2004) 27824-27829
2. Alonso A., Terrados G., Picher A.J., Giraldo R., Blanco L., and Larraga V. An intrinsic 5′-deoxyribose-5-phosphate lyase activity in DNA polymerase beta from Leishmania infantum supports a role in DNA repair. DNA Repair 5 (2006) 89-101
3. Alsford S., Kawahara T., Isamah C., and Horn D. A sirtuin in the African trypanosome is involved in both DNA repair and telomeric gene silencing but is not required for antigenic variation. Mol. Microbiol. 63 (2007) 724-736
4. Augusto-Pinto L., Bartholomeu D.C., Teixeira S.M.R., Pena S.D.J., and Machado C.R. Molecular cloning and characterization of the DNA mismatch repair gene class 2 from the Trypanosoma cruzi. Gene 272 (2001) 323-333
5. Aylon Y., and Kupiec M. DSB repair: the yeast paradigm. DNA Repair (Amst.) 3 (2004) 797-815
6. Bell J.S., Harvey T.I., Sims A.M., and McCulloch R. Characterization of components of the mismatch repair machinery in Trypanosoma brucei. Mol. Microbiol. 51 (2004) 159-173
7. Bhattacharyya M.K., and Kumar N. Identification and molecular characterisation of DNA damaging agent induced expression of Plasmodium falciparum recombination protein PfRad51. Int. J. Parasitol. 33 (2003) 1385-1392
8. Bhattacharyya M.K., Norris D.E., and Kumar N. Molecular players of homologous recombination in protozoan parasites: implications for generating antigenic variation. Infect. Genet. Evol. 4 (2004) 91-98
9. Bethke L., Thomas S., Walker K., Lakhia R., Rangarajan R., and Wirth D. The role of DNA mismatch repair in generating genetic diversity and drug resistance in malaria parasites. Mol. Biochem. Parasitol. 155 (2007) 18-25
10. Boiteux S., and Guillet M. Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae. DNA Repair (Amst.) 3 (2004) 1-12
11. Burton P., McBride D.J., Wilkes J.M., Barry J.D., and McCulloch R. Ku heterodimer-independent end joining in Trypanosoma brucei cell extracts relies upon sequence microhomology. Eukaryotic Cell 6 (2007) 1773-1781
12. Carlton J.M., Hirt R.P., Silva J.C., Delcher A.L., Schatz M., Zhao Q., Wortman J.R., Bidwell S.L., Alsmark U.C., Besteiro S., et al. Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. Science 315 (2007) 207-212
13. Casta L.J., Buguliskis J.S., Matsumoto Y., and Taraschi T.F. Expression and biochemical characterization of the Plasmodium falciparum DNA repair enzyme, flap endonuclease-1 (PfFEN-1). Mol. Biochem. Parasitol. 157 (2008) 1-12
14. Daley J.M., Palmbos P.L., Wu D., and Wilson T.E. Non-homologous end joining in yeast. Annu. Rev. Genet. 39 (2005) 431-451
15. Fleck O., and Nielsen O. DNA repair. J. Cell Sci. 117 (2004) 515-517
16. Gallego C., Estévez A.M., Fárez E., Ruiz-Pérez L.M., and González-Pacanowska D. Overexpression of AP endonuclease protects Leishmania major cells against methotrexate induced DNA fragmentation and hydrogen peroxide. Mol. Biochem. Parasitol. 141 (2005) 191-197
17. Gardner M.J., Hall N., Fung E., et al. Genome sequence of the human parasite Plasmodium falciparum. Nature 419 (2002) 498-511
18. Gill E.E., and Fast N.M. Stripped-down DNA repair in a highly reduced parasite. BMC Mol. Biol. 8 (2007) 24
19. Hefferin M.L., and Tomkinson A.E. Mechanism of DNA double-strand break repair by non-homologous end joining. DNA Repair (Amst.) 4 (2005) 639-648
20. Krokan H.E., Standal R., and Slupphaug G. DNA glycosylases in the base excision repair of DNA. Biochem. J. 325 (1997) 1-16
21. Longhese M.P., Mantiero D., and Clerici M. The cellular response to chromosome breakage. Mol. Microbiol. 60 (2006) 1099-1108
22. Lopez-Camarillo C., García-Hernández M.L., Marchat L.A., Luna-Arias J.P., Hernandez de la Cruz O., Mendoza L., and Orozco E. Entamoeba histolytica EhDEAD1 protein is a conserved DEAD-box RNA helicase with ATPase and ATP-dependent RNA unwinding activities. Gene 14 (2008) 19-31
23. Lopez-Casamichana M., Orozco E., Marchat L.A., and Lopez-Camarillo C. Insights in DNA repair and homologous recombination in Entamoeba histolytica: in silico characterization of EhMRN complex. Proceedings of the 5th European Congress on Tropical Medicine and International Health (2007) 7-11
24. Lopez-Casamichana M., Orozco E., Marchat L.A., and Lopez-Camarillo C. Transcriptional profile of the homologous recombination machinery and characterization of the EhRAD51 recombinase in response to DNA damage in Entamoeba histolytica. BMC Mol. Biol. 9 (2008) 35
25. Lukianova O.A., and David S.S. A role for iron-sulfur clusters in DNA repair. Curr. Opin. Chem. Biol. 9 (2005) 145-151
26. Marchat L.A., Orozco E., Guillen N., Weber C., and López-Camarillo C. Putative DEAD and DExH box RNA helicases families in Entamoeba histolytica. Gene 424 (2008) 1-10
27. Marti T.M., Kunz C., and Fleck O. DNA mismatch repair and mutation avoidance pathways. J. Cell Physiol. 191 (2002) 28-41
28. Mazin A.V., Alexeev A.A., and Kowalczykowski S.C. A novel function of Rad54 protein. Stabilization of the Rad51 nucleoprotein filament. J. Biol. Chem. 278 (2004) 14029-14036
29. McCulloch R., and Barry J.D. A role for RAD51 and homologous recombination in Trypanosoma brucei antigenic variation. Genes Dev. 13 (1999) 2875-2888
30. McKean P.G., Keen J.K., Smith D.F., and Benson F.E. Identification and characterisation of a RAD 51 gene from Leishmania major. Mol. Biochem. Parasitol. 115 (2001) 209-216
31. Perez J., Gallego C., Bernier-Villamor V., Camacho A., Gonzalez-Pacanowska D., and Ruiz-Perez L.M. Apurinic/apyrimidinic endonuclease genes from the trypanosomatidae leishmania major and Trypanosoma cruzi confer resistance to oxidizing agents in DNA repair-deficient Escherichia coli. Nucleic Acids Res. 27 (1999) 771-777
32. Prakash S., and Prakash L. Nucleotide excision repair in yeast. Mutat. Res. 451 (2000) 13-24
33. Proudfoot C., and McCulloch R. Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation. Nucleic Acids Res. 33 (2005) 6906-6919
34. Proudfoot C., and McCulloch R. Trypanosoma brucei DMC1 does not act in DNA recombination, repair or antigenic variation in bloodstream stage cells. Mol. Biochem. Parasitol. 145 (2006) 245-253
35. Ramesh M.A., Malik S.B., and Logsdon Jr. J.M. A phylogenomic inventory of meiotic genes: evidence for sex in Giardia and an early eukaryotic origin of meiosis. Curr. Biol. 15 (2005) 185-191
36. Sassanfar M., Dosanjh M.K., Essigmann J.M., and Samson L. Relative efficiencies of the bacterial, yeast, and human DNA methyltransferases for the repair of O6-methylguanine and O4-methylthymine. Suggestive evidence for O4-methylthymine repair by eukaryotic methyltransferases. J. Biol. Chem. 266 (1991) 2767-2771
37. Tan K.S., Leal S.T., and Cross G.A. Trypanosoma brucei MRE11 is non-essential but influences growth, homologous recombination and DNA double-strand break repair. Mol. Biochem. Parasitol. 125 (2002) 11-21
38. Vidal A.E., Harkiolaki M., Gallego C., Castillo-Acosta V.M., Ruiz-Pérez L.M., Wilson K., and González-Pacanowska D. Crystal structure and DNA repair activities of the AP endonuclease from Leishmania major. J. Mol. Biol. 373 (2007) 827-838
39. Voss T.S., Mini T., Jenoe P., and Beck H.P. Plasmodium falciparum possesses a cell cycle-regulated short type replication protein A large subunit encoded by an unusual transcript. J. Biol. Chem. 277 (2002) 17493-17501
40. Weber C., Marchat L.A., Guillen N., and López-Camarillo C. Effects of DNA damage induced by UV irradiation on gene expression in the protozoan parasite Entamoeba histolytica. Mol. Biochem. Parasitol. 164 (2009) 165-169
41. Wolner B., and Peterson C. ATP-dependent and ATP-independent roles for the Rad54 chromatin remodeling enzyme during recombination repair of a DNA double strand break. J. Biol. Chem. 280 (2006) 10855-10860