An intrinsic 5′-deoxyribose-5-phosphate lyase activity in DNA polymerase beta from Leishmania infantum supports a role in DNA repair

DNA Repair

Volumn 5, Issue 1, 2006, Pages 89-101

  Alonso, Ana ^a   Terrados, Gloria ^b   Picher, Angel J ^b   Giraldo, Rafael ^a   Blanco, Luis ^b   Larraga, Vicente ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b CSIC   (Spain)

Author keywords

BER; DNA polymerase beta; dRP lyase activity; Leishmania

Indexed keywords

5' DEOXYRIBOSE 5 PHOSPHATE LYASE; DEOXYRIBONUCLEIC ACID DIRECTED RIBONUCLEIC ACID POLYMERASE LAMBDA; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED RNA POLYMERASE; LYASE; MAGNESIUM ION; MANGANESE; UNCLASSIFIED DRUG; URACIL; 5' DEOXYRIBOSE PHOSPHATE LYASE; 5'-DEOXYRIBOSE PHOSPHATE LYASE; MAGNESIUM; RECOMBINANT PROTEIN;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; ENZYME PURIFICATION; ESCHERICHIA COLI; EXCISION REPAIR; INFECTION; LEISHMANIA INFANTUM; MACROPHAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN POLYMERIZATION; AMINO ACID SEQUENCE; ANIMAL; CELL INCLUSION; ENZYME SPECIFICITY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY;

ESCHERICHIA COLI; LEISHMANIA INFANTUM; MAMMALIA; PROTOZOA;

AMINO ACID SEQUENCE; ANIMALS; DNA POLYMERASE BETA; DNA REPAIR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INCLUSION BODIES; LEISHMANIA INFANTUM; MAGNESIUM; MANGANESE; MOLECULAR SEQUENCE DATA; PHOSPHORUS-OXYGEN LYASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 29244446769     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2005.08.001     Document Type: Article

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