Amyloid-beta associated with chitosan nano-carrier has favorable immunogenicity and permeates the BBB

AAPS PharmSciTech

Volumn 10, Issue 3, 2009, Pages 900-905

  Zhang, Songjiang ^a,b   Wu, Lixiang ^a  

^a Central South University   (China)

^b HENAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Amyloid beta; Blood brain barrier; Immunogenicity; Nanoparticle

Indexed keywords

AMYLOID BETA PROTEIN; CHITOSAN; IMMUNOGLOBULIN G; MICROSPHERE; NANOCARRIER;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; CHEMICAL STRUCTURE; CONTROLLED STUDY; CROSS LINKING; DRUG PENETRATION; DRUG UPTAKE; EMULSION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOGENICITY; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; TRANSMISSION ELECTRON MICROSCOPY;

ALZHEIMER VACCINES; AMYLOID BETA-PROTEIN; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CHITOSAN; CROSS-LINKING REAGENTS; DRUG CARRIERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOGLOBULIN G; INJECTIONS, INTRAPERITONEAL; MALE; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE;

EID: 70449534712     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9279-1     Document Type: Article

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