메뉴 건너뛰기




Volumn 45, Issue 12, 2009, Pages 1011-1014

Review of the molecular pathogenesis of the odontogenic keratocyst

Author keywords

Epigenetics; Genetics; Keratocystic odontogenic tumour; Odontogenic keratocyst; PTCH; Review

Indexed keywords

EPIGENETICS; GENE MUTATION; GENETIC ANALYSIS; HUMAN; ODONTOGENIC KERATOCYST; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

EID: 70449532124     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2009.08.003     Document Type: Review
Times cited : (54)

References (47)
  • 3
    • 0036227326 scopus 로고    scopus 로고
    • The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 1. Clinical and early experimental evidence of aggressive behaviour
    • Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 1. Clinical and early experimental evidence of aggressive behaviour. Oral Oncol 38 (2002) 219-226
    • (2002) Oral Oncol , vol.38 , pp. 219-226
    • Shear, M.1
  • 4
    • 0028411257 scopus 로고
    • Quantification of PCNA positive cells within odontogenic jaw cyst epithelium
    • Li T.J., Browne R.M., and Matthews J.B. Quantification of PCNA positive cells within odontogenic jaw cyst epithelium. J Oral Pathol Med 23 (1994) 184-189
    • (1994) J Oral Pathol Med , vol.23 , pp. 184-189
    • Li, T.J.1    Browne, R.M.2    Matthews, J.B.3
  • 5
    • 0029379594 scopus 로고
    • P53 protein and Ki-67 reactivity in epithelial odontogenic lesions. An immunohistochemical study
    • Slootweg P.J. P53 protein and Ki-67 reactivity in epithelial odontogenic lesions. An immunohistochemical study. J Oral Pathol Med 24 (1995) 393-397
    • (1995) J Oral Pathol Med , vol.24 , pp. 393-397
    • Slootweg, P.J.1
  • 6
    • 0029300689 scopus 로고
    • Epithelial cell proliferations in odontogenic keratocysts: a comparative immunocytochemical study of Ki67 in simple, recurrent and basal cell naevus syndrome (BCNS)-associated lesions
    • Li T.-J., Browne R.M., and Matthews J.B. Epithelial cell proliferations in odontogenic keratocysts: a comparative immunocytochemical study of Ki67 in simple, recurrent and basal cell naevus syndrome (BCNS)-associated lesions. J Oral Pathol Med 24 (1995) 221-226
    • (1995) J Oral Pathol Med , vol.24 , pp. 221-226
    • Li, T.-J.1    Browne, R.M.2    Matthews, J.B.3
  • 8
    • 0032169396 scopus 로고    scopus 로고
    • Expression of proliferating cell nuclear antigen in ameloblastomas and odontogenic cysts
    • Piattelli A., Fioroni M., Santinelli A., and Rubini C. Expression of proliferating cell nuclear antigen in ameloblastomas and odontogenic cysts. Oral Oncol 34 (1998) 408-412
    • (1998) Oral Oncol , vol.34 , pp. 408-412
    • Piattelli, A.1    Fioroni, M.2    Santinelli, A.3    Rubini, C.4
  • 9
    • 0033278117 scopus 로고    scopus 로고
    • Expression of cell cycle and apoptosis-related proteins in sporadic odontogenic keratocysts and odontogenic keratocysts associated with nevoid basal cell carcinoma syndrome
    • Lo Muzio L., Staibano S., Pannone G., Bucci P., Nocini P.F., Bucci E., et al. Expression of cell cycle and apoptosis-related proteins in sporadic odontogenic keratocysts and odontogenic keratocysts associated with nevoid basal cell carcinoma syndrome. J Dent Res 78 (1999) 1345-1353
    • (1999) J Dent Res , vol.78 , pp. 1345-1353
    • Lo Muzio, L.1    Staibano, S.2    Pannone, G.3    Bucci, P.4    Nocini, P.F.5    Bucci, E.6
  • 10
    • 0034934339 scopus 로고    scopus 로고
    • Immunohistochemical analysis of cell-cycle and apoptosis-related factor in lining epithelium of odontogenic keratocysts
    • Kimi K., Kumamoto H., Ooya K., and Motegi K. Immunohistochemical analysis of cell-cycle and apoptosis-related factor in lining epithelium of odontogenic keratocysts. J Oral Pathol Med 30 (2001) 434-442
    • (2001) J Oral Pathol Med , vol.30 , pp. 434-442
    • Kimi, K.1    Kumamoto, H.2    Ooya, K.3    Motegi, K.4
  • 11
    • 18244402873 scopus 로고    scopus 로고
    • MIB-1 expression in odontogenic epithelial rests, epithelium of healthy oral mucosa and epithelium of selected odontogenic cysts. An immunohistochemical study
    • Saraçoglu U., Kurt B., Günhan O., and Güven O. MIB-1 expression in odontogenic epithelial rests, epithelium of healthy oral mucosa and epithelium of selected odontogenic cysts. An immunohistochemical study. Int J Oral Maxillofac Surg 34 (2005) 432-435
    • (2005) Int J Oral Maxillofac Surg , vol.34 , pp. 432-435
    • Saraçoglu, U.1    Kurt, B.2    Günhan, O.3    Güven, O.4
  • 13
    • 0033973743 scopus 로고    scopus 로고
    • Evaluation of p53, PCNA, Ki-67, MDM-2 and AgNOR in oral peripheral and central giant cell lesions
    • Souza P.E.A., Mesquita R.A., and Gomez R.S. Evaluation of p53, PCNA, Ki-67, MDM-2 and AgNOR in oral peripheral and central giant cell lesions. Oral Diseases 6 (2000) 35-39
    • (2000) Oral Diseases , vol.6 , pp. 35-39
    • Souza, P.E.A.1    Mesquita, R.A.2    Gomez, R.S.3
  • 14
    • 24644463758 scopus 로고    scopus 로고
    • The use of molecular markers as an aid in the diagnosis of glandular odontogenic cyst
    • Kaplan I., Anavi Y., Manor R., Sulkes J., and Calderon S. The use of molecular markers as an aid in the diagnosis of glandular odontogenic cyst. Oral Oncol 41 (2005) 895-902
    • (2005) Oral Oncol , vol.41 , pp. 895-902
    • Kaplan, I.1    Anavi, Y.2    Manor, R.3    Sulkes, J.4    Calderon, S.5
  • 16
    • 28844482638 scopus 로고    scopus 로고
    • Molecular evidence supporting the neoplastic nature of odontogenic keratocyst: a laser capture microdissection study of 15 cases
    • Henley J., Summerlin D.-J., Tomich C., Zhang S., and Cheng L. Molecular evidence supporting the neoplastic nature of odontogenic keratocyst: a laser capture microdissection study of 15 cases. Histopathology 47 (2005) 582-586
    • (2005) Histopathology , vol.47 , pp. 582-586
    • Henley, J.1    Summerlin, D.-J.2    Tomich, C.3    Zhang, S.4    Cheng, L.5
  • 17
    • 42149144818 scopus 로고    scopus 로고
    • Alterations of FHIT and P53 genes in keratocystic odontogenic tumour, dentigerous cyst and radicular cyst
    • Malcić A, Jukić S, Anić I, Pavelić B, Kapitanović S, Kruslin B, et al. Alterations of FHIT and P53 genes in keratocystic odontogenic tumour, dentigerous cyst and radicular cyst. J Oral Pathol Med 2008;37:294-301.
    • (2008) J Oral Pathol Med , vol.37 , pp. 294-301
    • Malcić, A.1    Jukić, S.2    Anić, I.3    Pavelić, B.4    Kapitanović, S.5    Kruslin, B.6
  • 19
    • 0029421235 scopus 로고
    • P53 immunohistochemistry of odontogenic keratocyst in relation to recurrence, basal-cell budding and basal-cell naevus syndrome
    • Lombardi T., Odell E.W., and Morgan P.R. P53 immunohistochemistry of odontogenic keratocyst in relation to recurrence, basal-cell budding and basal-cell naevus syndrome. Archs Oral Biol 40 (1995) 1081-1084
    • (1995) Archs Oral Biol , vol.40 , pp. 1081-1084
    • Lombardi, T.1    Odell, E.W.2    Morgan, P.R.3
  • 21
    • 33748676131 scopus 로고    scopus 로고
    • Expression of p53, Ki-67, and EGFR in odontogenic keratocysts before and after decompression
    • Clark P., Marker P., Bastian H.L., and Krogdahl A. Expression of p53, Ki-67, and EGFR in odontogenic keratocysts before and after decompression. J Oral Pathol Med 35 (2006) 568-572
    • (2006) J Oral Pathol Med , vol.35 , pp. 568-572
    • Clark, P.1    Marker, P.2    Bastian, H.L.3    Krogdahl, A.4
  • 22
    • 34347205193 scopus 로고    scopus 로고
    • Genetic changes in sporadic keratocystic odontogenic tumors (Odontogenic Keratocysts)
    • Heikinheimo K., Jee K.J., Morgan P.R., Nagy B., Knuutila S., and Leiva I. Genetic changes in sporadic keratocystic odontogenic tumors (Odontogenic Keratocysts). J Dent Res 86 (2007) 544-549
    • (2007) J Dent Res , vol.86 , pp. 544-549
    • Heikinheimo, K.1    Jee, K.J.2    Morgan, P.R.3    Nagy, B.4    Knuutila, S.5    Leiva, I.6
  • 23
    • 0031420294 scopus 로고    scopus 로고
    • Characterisation of human patched germ line mutations in naevoid basal cell carcinoma syndrome
    • Lench N.J., Telford E.A., High A.S., Markham A.F., Wicking C., and Wainwright B.J. Characterisation of human patched germ line mutations in naevoid basal cell carcinoma syndrome. Hum Genet 100 (1997) 497-502
    • (1997) Hum Genet , vol.100 , pp. 497-502
    • Lench, N.J.1    Telford, E.A.2    High, A.S.3    Markham, A.F.4    Wicking, C.5    Wainwright, B.J.6
  • 26
    • 33748772228 scopus 로고    scopus 로고
    • PTCH mutations in sporadic and Gorlin-syndrome-related odontogenic keratocysts
    • Gu X.M., Zhao H.S., Sun L.S., and Li T.J. PTCH mutations in sporadic and Gorlin-syndrome-related odontogenic keratocysts. J Dent Res 85 (2006) 859-863
    • (2006) J Dent Res , vol.85 , pp. 859-863
    • Gu, X.M.1    Zhao, H.S.2    Sun, L.S.3    Li, T.J.4
  • 27
    • 45849150375 scopus 로고    scopus 로고
    • PTCH1 and SMO gene alterations in keratocystic odontogenic tumors
    • Sun L.S., Li X.F., and Li T.J. PTCH1 and SMO gene alterations in keratocystic odontogenic tumors. J Dent Res 87 (2008) 575-579
    • (2008) J Dent Res , vol.87 , pp. 575-579
    • Sun, L.S.1    Li, X.F.2    Li, T.J.3
  • 31
    • 0036827968 scopus 로고    scopus 로고
    • Immunolocalization of PTCH protein in odontogenic cysts and tumors
    • Barreto D.C., Bale A.E., De Marco L., and Gomez R.S. Immunolocalization of PTCH protein in odontogenic cysts and tumors. J Dent Res 81 (2002) 757-760
    • (2002) J Dent Res , vol.81 , pp. 757-760
    • Barreto, D.C.1    Bale, A.E.2    De Marco, L.3    Gomez, R.S.4
  • 32
    • 0029936752 scopus 로고    scopus 로고
    • Regulation of gene expression by alternative promoters
    • Ayoubi T.A., and Van De Ven W.J. Regulation of gene expression by alternative promoters. FASEB J 10 (1996) 453-460
    • (1996) FASEB J , vol.10 , pp. 453-460
    • Ayoubi, T.A.1    Van De Ven, W.J.2
  • 33
    • 0037026603 scopus 로고    scopus 로고
    • Alternative first exons of PTCH1 are differentially regulated in vivo and may confer different functions to the PTCH1 protein
    • Kogerman P., Krause D., Rahnama F., Kogerman L., Undén A.B., Zaphiropoulos P.G., et al. Alternative first exons of PTCH1 are differentially regulated in vivo and may confer different functions to the PTCH1 protein. Oncogene 21 (2002) 6007-6016
    • (2002) Oncogene , vol.21 , pp. 6007-6016
    • Kogerman, P.1    Krause, D.2    Rahnama, F.3    Kogerman, L.4    Undén, A.B.5    Zaphiropoulos, P.G.6
  • 34
    • 9644253204 scopus 로고    scopus 로고
    • A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions
    • Shimokawa T., Rahnama F., and Zaphiropoulos P.G. A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions. FEBS Lett 578 (2004) 157-162
    • (2004) FEBS Lett , vol.578 , pp. 157-162
    • Shimokawa, T.1    Rahnama, F.2    Zaphiropoulos, P.G.3
  • 35
    • 1842839986 scopus 로고    scopus 로고
    • Expression of the PTCH1 tumour suppressor gene is regulated by alternative promoters and a single functional Gli-binding site
    • Agren M., Kogerman P., Kleman M.I., Wessling M., and Toftgård R. Expression of the PTCH1 tumour suppressor gene is regulated by alternative promoters and a single functional Gli-binding site. Gene 330 (2004) 101-114
    • (2004) Gene , vol.330 , pp. 101-114
    • Agren, M.1    Kogerman, P.2    Kleman, M.I.3    Wessling, M.4    Toftgård, R.5
  • 36
    • 15244362560 scopus 로고    scopus 로고
    • Identification and characterization of multiple isoforms of a murine and human tumour suppressor, patched, having distinct first exons
    • Nagao K., Toyoda M., Takeuchi-Inoue K., Fujii K., Yamada M., and Miyashita T. Identification and characterization of multiple isoforms of a murine and human tumour suppressor, patched, having distinct first exons. Genomics 85 (2005) 462-471
    • (2005) Genomics , vol.85 , pp. 462-471
    • Nagao, K.1    Toyoda, M.2    Takeuchi-Inoue, K.3    Fujii, K.4    Yamada, M.5    Miyashita, T.6
  • 39
    • 0042063840 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations of 9p21 gene products in benign and malignant tumors of head and neck
    • Weber A., Wittekind C., and Tannapfel A. Genetic and epigenetic alterations of 9p21 gene products in benign and malignant tumors of head and neck. Pathol Res Pract 199 (2003) 391-397
    • (2003) Pathol Res Pract , vol.199 , pp. 391-397
    • Weber, A.1    Wittekind, C.2    Tannapfel, A.3
  • 40
    • 0034305821 scopus 로고    scopus 로고
    • DNA methylation in health and disease
    • Robertson K.D., and Wolffe A.P. DNA methylation in health and disease. Nat Rev Genet 1 (2000) 11-19
    • (2000) Nat Rev Genet , vol.1 , pp. 11-19
    • Robertson, K.D.1    Wolffe, A.P.2
  • 41
    • 0037154963 scopus 로고    scopus 로고
    • Cooperation between complexes that regulate chromatin structure and transcription
    • Narlikar G.J., Fan H.Y., and Kingston R.E. Cooperation between complexes that regulate chromatin structure and transcription. Cell 108 (2002) 475-487
    • (2002) Cell , vol.108 , pp. 475-487
    • Narlikar, G.J.1    Fan, H.Y.2    Kingston, R.E.3
  • 42
    • 34548580238 scopus 로고    scopus 로고
    • The Patched gene is epigenetically regulated in ovarian dermoids and fibromas, but not in basocellular carcinomas
    • Cretnik M., Musani V., Oreskovic S., Leovic D., and Levanat S. The Patched gene is epigenetically regulated in ovarian dermoids and fibromas, but not in basocellular carcinomas. Int J Mol Med 19 (2007) 875-883
    • (2007) Int J Mol Med , vol.19 , pp. 875-883
    • Cretnik, M.1    Musani, V.2    Oreskovic, S.3    Leovic, D.4    Levanat, S.5
  • 43
    • 36549018606 scopus 로고    scopus 로고
    • Methylation of PTCH1, the Patched 1 gene, in a panel of medulloblastoma
    • Pritchard J.E., and Olson J.M. Methylation of PTCH1, the Patched 1 gene, in a panel of medulloblastoma. Cancer Genet Cytogenet 180 (2008) 47-50
    • (2008) Cancer Genet Cytogenet , vol.180 , pp. 47-50
    • Pritchard, J.E.1    Olson, J.M.2
  • 44
    • 34247365397 scopus 로고    scopus 로고
    • Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer
    • Wolf I., Bose S., Desmond J.C., Lin B.T., Williamson E.A., Karlan B.Y., et al. Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer. Breast Cancer Res Treat 105 (2007) 139-155
    • (2007) Breast Cancer Res Treat , vol.105 , pp. 139-155
    • Wolf, I.1    Bose, S.2    Desmond, J.C.3    Lin, B.T.4    Williamson, E.A.5    Karlan, B.Y.6
  • 46
    • 27244432205 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumour suppressors
    • Chen C.Z. MicroRNAs as oncogenes and tumour suppressors. N Engl J Med 353 (2005) 1768-1771
    • (2005) N Engl J Med , vol.353 , pp. 1768-1771
    • Chen, C.Z.1
  • 47
    • 51649095834 scopus 로고    scopus 로고
    • MicroRNA and oral cancer: future perspectives
    • Gomes C.C., and Gomez R.S. MicroRNA and oral cancer: future perspectives. Oral Oncol 44 (2008) 910-914
    • (2008) Oral Oncol , vol.44 , pp. 910-914
    • Gomes, C.C.1    Gomez, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.