-
1
-
-
0034108013
-
Bioavailability and metabolism of the flavonol quercetin in the pig
-
Ader P., Wessmann S., and Wolffram S. Bioavailability and metabolism of the flavonol quercetin in the pig. Free Radic. Biol. Med. 28 (2000) 1056-1067
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 1056-1067
-
-
Ader, P.1
Wessmann, S.2
Wolffram, S.3
-
2
-
-
53349109650
-
Influence of green and black tea on folic acid pharmacokinetics in healthy volunteers: potential risk of diminished folic acid bioavailability
-
Alemdaroglu N.C., Dietz U., Wolffram S., Spahn-Langguth H., and Langguth P. Influence of green and black tea on folic acid pharmacokinetics in healthy volunteers: potential risk of diminished folic acid bioavailability. Biopharm. Drug Dispos. 29 (2008) 335-348
-
(2008)
Biopharm. Drug Dispos.
, vol.29
, pp. 335-348
-
-
Alemdaroglu, N.C.1
Dietz, U.2
Wolffram, S.3
Spahn-Langguth, H.4
Langguth, P.5
-
3
-
-
0033846824
-
Plasma concentrations of active simvastatin acid are increased by gemfibrozil
-
Backman J.T., Kyrklund C., Kivistö K.T., Wang J.S., and Neuvonen P.J. Plasma concentrations of active simvastatin acid are increased by gemfibrozil. Clin. Pharmacol. Ther. 68 (2000) 122-129
-
(2000)
Clin. Pharmacol. Ther.
, vol.68
, pp. 122-129
-
-
Backman, J.T.1
Kyrklund, C.2
Kivistö, K.T.3
Wang, J.S.4
Neuvonen, P.J.5
-
4
-
-
33947420519
-
Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice
-
Bailey D.G., Dresser G.K., Leake B.F., and Kim R.B. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Clin. Pharmacol. Ther. 81 (2007) 495-502
-
(2007)
Clin. Pharmacol. Ther.
, vol.81
, pp. 495-502
-
-
Bailey, D.G.1
Dresser, G.K.2
Leake, B.F.3
Kim, R.B.4
-
5
-
-
49449084484
-
Tissue distribution of quercetin in pigs after long-term dietary supplementation
-
Bieger J., Cermak R., Blank R., de Boer V.C.J., Hollman P.C.H., Kamphues J., and Wolffram S. Tissue distribution of quercetin in pigs after long-term dietary supplementation. J. Nutr. 138 (2008) 1417-1420
-
(2008)
J. Nutr.
, vol.138
, pp. 1417-1420
-
-
Bieger, J.1
Cermak, R.2
Blank, R.3
de Boer, V.C.J.4
Hollman, P.C.H.5
Kamphues, J.6
Wolffram, S.7
-
6
-
-
0031721802
-
Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance
-
Bravo L. Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nutr. Rev. 56 (1998) 317-333
-
(1998)
Nutr. Rev.
, vol.56
, pp. 317-333
-
-
Bravo, L.1
-
7
-
-
0042419922
-
The bioavailability of quercetin in pigs depends on the glycoside moiety and on dietary factors
-
Cermak R., Landgraf S., and Wolffram S. The bioavailability of quercetin in pigs depends on the glycoside moiety and on dietary factors. J. Nutr. 133 (2003) 2802-2807
-
(2003)
J. Nutr.
, vol.133
, pp. 2802-2807
-
-
Cermak, R.1
Landgraf, S.2
Wolffram, S.3
-
8
-
-
33749444911
-
The potential of flavonoids to influence drug metabolism and pharmacokinetics by local gastrointestinal mechanisms
-
Cermak R., and Wolffram S. The potential of flavonoids to influence drug metabolism and pharmacokinetics by local gastrointestinal mechanisms. Curr. Drug Metab. 7 (2006) 729-744
-
(2006)
Curr. Drug Metab.
, vol.7
, pp. 729-744
-
-
Cermak, R.1
Wolffram, S.2
-
9
-
-
0034721761
-
Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation
-
Draganov D.I., Stetson P.L., Watson C.E., Billecke S.E., and La Du B.N. Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation. J. Biol. Chem. 275 (2000) 33435-33442
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33435-33442
-
-
Draganov, D.I.1
Stetson, P.L.2
Watson, C.E.3
Billecke, S.E.4
La Du, B.N.5
-
10
-
-
27144469821
-
Flavonols, flavones, flavanones, and human health: epidemiological evidence
-
Graf B.A., Milbury P.E., and Blumberg J.B. Flavonols, flavones, flavanones, and human health: epidemiological evidence. J. Med. Food 8 (2005) 281-290
-
(2005)
J. Med. Food
, vol.8
, pp. 281-290
-
-
Graf, B.A.1
Milbury, P.E.2
Blumberg, J.B.3
-
11
-
-
0029075936
-
In vitro inhibition of midazolam and quinidine metabolism by flavonoids
-
Ha H.R., Chen J., Leuenberger P.M., Freiburghaus A.U., and Follath F. In vitro inhibition of midazolam and quinidine metabolism by flavonoids. Eur. J. Clin. Pharmacol. 48 (1995) 367-371
-
(1995)
Eur. J. Clin. Pharmacol.
, vol.48
, pp. 367-371
-
-
Ha, H.R.1
Chen, J.2
Leuenberger, P.M.3
Freiburghaus, A.U.4
Follath, F.5
-
12
-
-
0027291905
-
Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands
-
Hertog M.G.L., Hollman P.C.H., Katan M.B., and Kromhout D. Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands. Nutr. Cancer 20 (1993) 21-29
-
(1993)
Nutr. Cancer
, vol.20
, pp. 21-29
-
-
Hertog, M.G.L.1
Hollman, P.C.H.2
Katan, M.B.3
Kromhout, D.4
-
13
-
-
0031670167
-
Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations
-
Kantola T., Kivistö K.T., and Neuvonen P.J. Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. Clin. Pharmacol. Ther. 64 (1998) 177-182
-
(1998)
Clin. Pharmacol. Ther.
, vol.64
, pp. 177-182
-
-
Kantola, T.1
Kivistö, K.T.2
Neuvonen, P.J.3
-
14
-
-
0037116642
-
Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey
-
Kaufman D.W., Kelly J.P., Rosenberg L., Anderson T.E., and Mitchell A.A. Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. JAMA 287 (2002) 337-344
-
(2002)
JAMA
, vol.287
, pp. 337-344
-
-
Kaufman, D.W.1
Kelly, J.P.2
Rosenberg, L.3
Anderson, T.E.4
Mitchell, A.A.5
-
15
-
-
0035928640
-
Long-term trends in the use of complementary and alternative medical therapies in the United States
-
Kessler R.C., Davis R.B., Foster D.F., Van Rompay M.I., Walters E.E., Wilkey S.A., Kaptchuk T.J., and Eisenberg D.M. Long-term trends in the use of complementary and alternative medical therapies in the United States. Ann. Intern. Med. 135 (2001) 262-268
-
(2001)
Ann. Intern. Med.
, vol.135
, pp. 262-268
-
-
Kessler, R.C.1
Davis, R.B.2
Foster, D.F.3
Van Rompay, M.I.4
Walters, E.E.5
Wilkey, S.A.6
Kaptchuk, T.J.7
Eisenberg, D.M.8
-
16
-
-
0026464616
-
Identification of rifampicin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
-
Kolars J.C., Schmiedlin-Ren P., Schuetz J.D., Fang C., and Watkins P.B. Identification of rifampicin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J. Clin. Invest. 90 (1992) 1871-1878
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 1871-1878
-
-
Kolars, J.C.1
Schmiedlin-Ren, P.2
Schuetz, J.D.3
Fang, C.4
Watkins, P.B.5
-
17
-
-
3042696744
-
How should we assess the effects of exposure to dietary polyphenols in vitro
-
Kroon P.A., Clifford M.N., Crozier A., Day A.J., Donovan J.L., Manach C., and Williamson G. How should we assess the effects of exposure to dietary polyphenols in vitro. Am. J. Clin. Nutr. 80 (2004) 15-21
-
(2004)
Am. J. Clin. Nutr.
, vol.80
, pp. 15-21
-
-
Kroon, P.A.1
Clifford, M.N.2
Crozier, A.3
Day, A.J.4
Donovan, J.L.5
Manach, C.6
Williamson, G.7
-
18
-
-
0033637140
-
The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
-
Middleton E., Kandaswami C., and Theoharides T.C. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol. Rev. 52 (2000) 673-751
-
(2000)
Pharmacol. Rev.
, vol.52
, pp. 673-751
-
-
Middleton, E.1
Kandaswami, C.2
Theoharides, T.C.3
-
19
-
-
0026771041
-
Inhibition of dihydropyridine metabolism in rat and human liver microsomes by flavonoids found in grapefruit juice
-
Miniscalco A., Lundahl J., Regardh C.G., Edgar B., and Eriksson U.G. Inhibition of dihydropyridine metabolism in rat and human liver microsomes by flavonoids found in grapefruit juice. J. Pharmacol. Exp. Ther. 261 (1992) 1195-1199
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.261
, pp. 1195-1199
-
-
Miniscalco, A.1
Lundahl, J.2
Regardh, C.G.3
Edgar, B.4
Eriksson, U.G.5
-
20
-
-
33644914487
-
Flavonoid-drug interactions: effects of flavonoids on ABC transporters
-
Morris M.E., and Zhang S. Flavonoid-drug interactions: effects of flavonoids on ABC transporters. Life Sci. 78 (2006) 2116-2130
-
(2006)
Life Sci.
, vol.78
, pp. 2116-2130
-
-
Morris, M.E.1
Zhang, S.2
-
21
-
-
45549091043
-
Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin
-
Neuvonen P.J., Backman J.T., and Niemi M. Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin. Clin. Pharmacokinet. 47 (2008) 463-474
-
(2008)
Clin. Pharmacokinet.
, vol.47
, pp. 463-474
-
-
Neuvonen, P.J.1
Backman, J.T.2
Niemi, M.3
-
22
-
-
33845420011
-
Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance
-
Neuvonen P.J., Niemi M., and Backman J.T. Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. Clin. Pharmacol. Ther. 80 (2006) 565-581
-
(2006)
Clin. Pharmacol. Ther.
, vol.80
, pp. 565-581
-
-
Neuvonen, P.J.1
Niemi, M.2
Backman, J.T.3
-
23
-
-
19444385262
-
Modulation of drug transport by selected flavonoids: involvement of P-gp and OCT?
-
Ofer M., Wolffram S., Koggel A., Spahn-Langguth H., and Langguth P. Modulation of drug transport by selected flavonoids: involvement of P-gp and OCT?. Eur. J. Pharm. Sci. 25 (2005) 263-271
-
(2005)
Eur. J. Pharm. Sci.
, vol.25
, pp. 263-271
-
-
Ofer, M.1
Wolffram, S.2
Koggel, A.3
Spahn-Langguth, H.4
Langguth, P.5
-
24
-
-
0030812885
-
In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450S
-
Prueksaritanont T., Gorham L.M., Ma B., Liu L., Yu X., Zhao J.J., Slaughter D.E., Arison B.H., and Vyas K.P. In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450S. Drug Metab. Dispos. 25 (1997) 1191-1199
-
(1997)
Drug Metab. Dispos.
, vol.25
, pp. 1191-1199
-
-
Prueksaritanont, T.1
Gorham, L.M.2
Ma, B.3
Liu, L.4
Yu, X.5
Zhao, J.J.6
Slaughter, D.E.7
Arison, B.H.8
Vyas, K.P.9
-
25
-
-
0038336614
-
The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6
-
Prueksaritanont T., Ma B., and Yu N. The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6. Br. J. Clin. Pharmacol. 56 (2003) 120-124
-
(2003)
Br. J. Clin. Pharmacol.
, vol.56
, pp. 120-124
-
-
Prueksaritanont, T.1
Ma, B.2
Yu, N.3
-
26
-
-
0036787498
-
Prevalence of complementary and alternative medicine use: state-specific estimates from the 2001 behavioral risk factor surveillance system
-
Rafferty A.P., McGee H.B., Miller C.E., and Reyes M. Prevalence of complementary and alternative medicine use: state-specific estimates from the 2001 behavioral risk factor surveillance system. Am. J. Public Health 92 (2002) 1598-1600
-
(2002)
Am. J. Public Health
, vol.92
, pp. 1598-1600
-
-
Rafferty, A.P.1
McGee, H.B.2
Miller, C.E.3
Reyes, M.4
-
27
-
-
0028036727
-
Selective biotransformation of taxol to 6a-hydroxytaxol by human cytochrome P450 2C8
-
Rahman A., Korzekwa K.R., Grogan J., Gonzalez F.J., and Harris J.W. Selective biotransformation of taxol to 6a-hydroxytaxol by human cytochrome P450 2C8. Cancer Res. 54 (1994) 5543-5546
-
(1994)
Cancer Res.
, vol.54
, pp. 5543-5546
-
-
Rahman, A.1
Korzekwa, K.R.2
Grogan, J.3
Gonzalez, F.J.4
Harris, J.W.5
-
29
-
-
0037403686
-
Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products
-
Raucy J.L. Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products. Drug Metab. Dispos. 31 (2003) 533-539
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 533-539
-
-
Raucy, J.L.1
-
30
-
-
0036223831
-
Summary of information on human CYP enzymes: human P450 metabolism data
-
Rendic S. Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab. Rev. 34 (2002) 83-448
-
(2002)
Drug Metab. Rev.
, vol.34
, pp. 83-448
-
-
Rendic, S.1
-
31
-
-
0028792438
-
Flavonoids in grapefruit juice inhibit the in vitro hepatic metabolism of 17b-estradiol
-
Schubert W., Eriksson U., Edgar B., Cullberg G., and Hedner T. Flavonoids in grapefruit juice inhibit the in vitro hepatic metabolism of 17b-estradiol. Eur. J. Drug Metab. Pharmacokinet. 20 (1995) 219-224
-
(1995)
Eur. J. Drug Metab. Pharmacokinet.
, vol.20
, pp. 219-224
-
-
Schubert, W.1
Eriksson, U.2
Edgar, B.3
Cullberg, G.4
Hedner, T.5
-
32
-
-
0028587863
-
Variable activation of lovastatin by hydrolytic enzymes in human plasma and liver
-
Tang B.K., and Kalow W. Variable activation of lovastatin by hydrolytic enzymes in human plasma and liver. Eur. J. Clin. Pharmacol. 47 (1995) 449-451
-
(1995)
Eur. J. Clin. Pharmacol.
, vol.47
, pp. 449-451
-
-
Tang, B.K.1
Kalow, W.2
-
33
-
-
43249129320
-
Pharmacokinetics of the CYP 3A substrate simvastatin following administration of delayed versus immediate release oral dosage forms
-
Tubic-Grozdanis M., Hilfinger J.M., Amidon G.L., Kim J.S., Kijek P., Staubach P., and Langguth P. Pharmacokinetics of the CYP 3A substrate simvastatin following administration of delayed versus immediate release oral dosage forms. Pharm. Res. 25 (2008) 1591-1600
-
(2008)
Pharm. Res.
, vol.25
, pp. 1591-1600
-
-
Tubic-Grozdanis, M.1
Hilfinger, J.M.2
Amidon, G.L.3
Kim, J.S.4
Kijek, P.5
Staubach, P.6
Langguth, P.7
-
34
-
-
0034773713
-
Variable plasma/liver and tissue esterase hydrolysis of simvastatin in healthy volunteers after a single oral dose
-
Vree T.B., Dammers E., Ulc I., Horkovics-Kovats S., Ryska M., and Merkx I. Variable plasma/liver and tissue esterase hydrolysis of simvastatin in healthy volunteers after a single oral dose. Clin. Drug Investig. 21 (2001) 643-652
-
(2001)
Clin. Drug Investig.
, vol.21
, pp. 643-652
-
-
Vree, T.B.1
Dammers, E.2
Ulc, I.3
Horkovics-Kovats, S.4
Ryska, M.5
Merkx, I.6
-
35
-
-
27544453625
-
Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators
-
Wang X., Wolkoff A.W., and Morris M.E. Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators. Drug Metab. Dispos. 33 (2005) 1666-1672
-
(2005)
Drug Metab. Dispos.
, vol.33
, pp. 1666-1672
-
-
Wang, X.1
Wolkoff, A.W.2
Morris, M.E.3
-
36
-
-
0036291921
-
Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors
-
Williams D., and Feely J. Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors. Clin. Pharmacokinet. 41 (2002) 343-370
-
(2002)
Clin. Pharmacokinet.
, vol.41
, pp. 343-370
-
-
Williams, D.1
Feely, J.2
|