In silico saturation mutagenesis and docking screening for the analysis of protein-ligand interaction: The endothelial protein C receptor case study

BMC Bioinformatics

Volumn 10, Issue SUPPL. 12, 2009, Pages

  Chiappori, Federica ^a,b   D'Ursi, Pasqualina ^a,b   Merelli, Ivan ^a   Milanesi, Luciano ^a   Rovida, Ermanna ^a  

^a CNR   (Italy)

^b Consorzio Interuniversitario Lombardo per l'Elaborazione Automatica ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINDING SITES; BINS; COMPLEXATION; GLYCOPROTEINS; LIGANDS; MUTAGENESIS;

COMPUTATIONAL PROCEDURES; EXTENSIVE EXPLORATIONS; LIGAND BINDING AFFINITY; MOLECULAR DOCKING SIMULATIONS; PAIR-WISE COMBINATIONS; PROTEIN-LIGAND COMPLEXES; PROTEIN-LIGAND INTERACTIONS; SATURATION MUTAGENESIS;

PROTEINS;

ENDOTHELIAL PROTEIN C RECEPTOR;

ARTICLE; BINDING AFFINITY; BINDING SITE; CASE STUDY; COMPUTER MODEL; CONTROLLED STUDY; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR RECOGNITION; MUTAGENESIS; MUTANT; PROTEIN LIPID INTERACTION; WILD TYPE;

EID: 70449512764     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-10-S12-S3     Document Type: Article

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