Overexpression of glycogen synthase kinase 3β sensitizes neuronal cells to ethanol toxicity

Journal of Neuroscience Research

Volumn 87, Issue 12, 2009, Pages 2793-2802

  Liu, Ying ^a   Chen, Gang ^b   Ma, Cuiling ^c   Bower, Kimberly A ^b   Xu, Mei ^b   Fan, Zhiqin ^a   Shi, Xianglin ^b   Ke, Zun Ji ^a   Luo, Jia ^a,b  

^a Chinese Academy of Sciences   (China)

^b UNIVERSITY OF KENTUCKY   (United States)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Alcohol; Apoptosis; Development; Fetal alcohol syndrome; Neurodegeneration

Indexed keywords

ALCOHOL; CASPASE 3; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; GLYCOGEN SYNTHASE KINASE 3BETA INHIBITOR; LITHIUM DERIVATIVE; MUTANT PROTEIN; PROTEIN BAX; SERINE; TDZD 8; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; CELL VIABILITY; CONTROLLED STUDY; DEPHOSPHORYLATION; DRUG PROTEIN BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBSTRATE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; WILD TYPE;

ALCOHOL-INDUCED DISORDERS, NERVOUS SYSTEM; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; FEMALE; FETAL ALCOHOL SYNDROME; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LITHIUM; MICE; MICE, INBRED C57BL; NERVE DEGENERATION; NEURONS; PREGNANCY;

EID: 70449498993     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22098     Document Type: Article

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