CRK9 contributes to regulation of mitosis and cytokinesis in the procyclic form of Trypanosoma brucei

BMC Cell Biology

Volumn 10, Issue , 2009, Pages 68-

  Gourguechon, Stephane ^a   Wang, Ching C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CDC2 RELATED KINASE; CDC2 RELATED KINASE 10; CDC2 RELATED KINASE 11; CDC2 RELATED KINASE 12; CDC2 RELATED KINASE 7; CDC2 RELATED KINASE 8; CDC2 RELATED KINASE 9; CYCLINE; PHENYLALANINE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL NUCLEUS; CELL SHAPE; CYTOKINESIS; DATA BASE; GENOME; IN VITRO STUDY; KINETOPLAST; KINETOSOME; MITOSIS; NONHUMAN; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN MOTIF; RNA INTERFERENCE; TRYPANOSOMA BRUCEI;

PYRONIA TITHONUS; TRYPANOSOMA BRUCEI;

ANIMALS; CDC2-CDC28 KINASES; CYCLINS; CYTOKINESIS; MITOSIS; PHENOTYPE; PROTOZOAN PROTEINS; RNA INTERFERENCE; TRYPANOSOMA BRUCEI BRUCEI;

EID: 70449369736     PISSN: None     EISSN: 14712121     Source Type: Journal    
DOI: 10.1186/1471-2121-10-68     Document Type: Article

References (47)

1. Naula C, Parsons M, Mottram JC. Protein kinases as drug targets in trypanosomes and Leishmania. Biochim Biophys Acta 2005, 1754(1-2):151-159. 1452262, 16198642.
2. Parsons M, Worthey EA, Ward PN, Mottram JC. Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi. BMC Genomics 2005, 6:127. 10.1186/1471-2164-6-127, 1266030, 16164760.
3. Evans T, Rosenthal ET, Youngblom J, Distel D, Hunt T. Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell 1983, 33(2):389-396. 10.1016/0092-8674(83)90420-8, 6134587.
4. Elledge SJ. Cell cycle checkpoints: preventing an identity crisis. Science 1996, 274(5293):1664-1672. 10.1126/science.274.5293.1664, 8939848.
5. Jackman MR, Pines JN. Cyclins and the G2/M transition. Cancer Surv 1997, 29:47-73.
6. Johnson DG, Walker CL. Cyclins and cell cycle checkpoints. Annu Rev Pharmacol Toxicol 1999, 39:295-312. 10.1146/annurev.pharmtox.39.1.295, 10331086.
7. Mendenhall MD, Hodge AE. Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 1998, 62(4):1191-1243. 98944, 9841670.
8. Murray A. Cyclin ubiquitination: the destructive end of mitosis. Cell 1995, 81(2):149-152. 10.1016/0092-8674(95)90322-4, 7736567.
9. Murray AW. Cyclin-dependent kinases: regulators of the cell cycle and more. Chem Biol 1994, 1(4):191-195. 10.1016/1074-5521(94)90009-4, 9383389.
10. Nasmyth K, Hunt T. Cell cycle. Dams and sluices. Nature 1993, 366(6456):634-635. 10.1038/366634a0, 8259207.
11. Murray AW. Recycling the cell cycle: cyclins revisited. Cell 2004, 116(2):221-234. 10.1016/S0092-8674(03)01080-8, 14744433.
12. Nurse P, Thuriaux P, Nasmyth K. Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet 1976, 146(2):167-178. 10.1007/BF00268085, 958201.
13. Cross GA. African trypanosomes in the 21st century: what is their future in science and in health?. Int J Parasitol 2001, 31(5-6):427-433. 10.1016/S0020-7519(01)00141-2, 11334926.
14. Stevens JR, Gibson WC. The evolution of pathogenic trypanosomes. Cad Saude Publica 1999, 15(4):673-684. 10.1590/S0102-311X1999000400002, 10633190.
15. Simpson L. Isolation of maxicircle component of kinetoplast DNA from hemoflagellate protozoa. Proc Natl Acad Sci USA 1979, 76(4):1585-1588. 10.1073/pnas.76.4.1585, 383434, 286999.
16. Robinson DR, Sherwin T, Ploubidou A, Byard EH, Gull K. Microtubule polarity and dynamics in the control of organelle positioning, segregation, and cytokinesis in the trypanosome cell cycle. J Cell Biol 1995, 128(6):1163-1172. 10.1083/jcb.128.6.1163, 2120423, 7896879.
17. Fairlamb AH, Weislogel PO, Hoeijmakers JH, Borst P. Isolation and characterization of kinetoplast DNA from bloodstream form of Trypanosoma brucei. J Cell Biol 1978, 76(2):293-309. 10.1083/jcb.76.2.293, 2109978, 10605439.
18. Morgan GW, Denny PW, Vaughan S, Goulding D, Jeffries TR, Smith DF, Gull K, Field MC. An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei. Mol Cell Biol 2005, 25(9):3774-3783. 10.1128/MCB.25.9.3774-3783.2005, 1084284, 15831481.
19. Matthews KR, Gull K. Cycles within cycles: the interplay between differentiation and cell division in Trypanosoma brucei. Parasitol Today 1994, 10(12):473-476. 10.1016/0169-4758(94)90159-7, 15275515.
20. McKean PG. Coordination of cell cycle and cytokinesis in Trypanosoma brucei. Curr Opin Microbiol 2003, 6(6):600-607. 10.1016/j.mib.2003.10.010, 14662356.
21. Ploubidou A, Robinson DR, Docherty RC, Ogbadoyi EO, Gull K. Evidence for novel cell cycle checkpoints in trypanosomes: kinetoplast segregation and cytokinesis in the absence of mitosis. J Cell Sci 1999, 112(Pt 24):4641-4650.
22. Gull K. Host-parasite interactions and trypanosome morphogenesis: a flagellar pocketful of goodies. Curr Opin Microbiol 2003, 6(4):365-370. 10.1016/S1369-5274(03)00092-4, 12941406.
23. Mottram JC, Smith G. A family of trypanosome cdc2-related protein kinases. Gene 1995, 162(1):147-152. 10.1016/0378-1119(95)00350-F, 7557404.
24. Li Z, Wang CC. A PHO80-like cyclin and a B-type cyclin control the cell cycle of the procyclic form of Trypanosoma brucei. J Biol Chem 2003, 278(23):20652-20658. 10.1074/jbc.M301635200, 12665514.
25. Van Hellemond JJ, Neuville P, Schwarz RT, Matthews KR, Mottram JC. Isolation of Trypanosoma brucei CYC2 and CYC3 cyclin genes by rescue of a yeast G(1) cyclin mutant. Functional characterization of CYC2. J Biol Chem 2000, 275(12):8315-8323. 10.1074/jbc.275.12.8315, 10722661.
26. Tu X, Wang CC. The involvement of two cdc2-related kinases (CRKs) in Trypanosoma brucei cell cycle regulation and the distinctive stage-specific phenotypes caused by CRK3 depletion. J Biol Chem 2004, 279(19):20519-20528. 10.1074/jbc.M312862200, 15010459.
27. Hammarton TC, Clark J, Douglas F, Boshart M, Mottram JC. Stage-specific differences in cell cycle control in Trypanosoma brucei revealed by RNA interference of a mitotic cyclin. J Biol Chem 2003, 278(25):22877-22886. 10.1074/jbc.M300813200, 12682070.
28. Gourguechon S, Savich JM, Wang CC. The multiple roles of cyclin E1 in controlling cell cycle progression and cellular morphology of Trypanosoma brucei. J Mol Biol 2007, 368(4):939-950. 10.1016/j.jmb.2007.02.050, 2701699, 17376478.
29. Gull K. The cell biology of parasitism in Trypanosoma brucei: insights and drug targets from genomic approaches?. Curr Pharm Des 2002, 8(4):241-256. 10.2174/1381612023396212, 11860364.
30. Sambrook J, Russell D. Molecular Cloning: A Laboratory Manual. 2001, Cold Spring Harbor, USA: CSHL press, Third.
31. Schimanski LA, Ali DW, Baker GB, Nguyen PV. Impaired hippocampal LTP in inbred mouse strains can be rescued by beta-adrenergic receptor activation. Eur J Neurosci 2007, 25(5):1589-1598. 10.1111/j.1460-9568.2007.05376.x, 17425584.
32. Tu X, Kumar P, Li Z, Wang CC. An aurora kinase homologue is involved in regulating both mitosis and cytokinesis in Trypanosoma brucei. J Biol Chem 2006, 281(14):9677-9687. 10.1074/jbc.M511504200, 16436376.
33. Kumar P, Wang CC. Dissociation of cytokinesis initiation from mitotic control in a eukaryote. Eukaryot Cell 2006, 5(1):92-102. 10.1128/EC.5.1.92-102.2006, 1360254, 16400171.
34. Woodward R, Gull K. Timing of nuclear and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma brucei. J Cell Sci 1990, 95(Pt 1):49-57.
35. Das A, Gale M, Carter V, Parsons M. The protein phosphatase inhibitor okadaic acid induces defects in cytokinesis and organellar genome segregation in Trypanosoma brucei. J Cell Sci 1994, 107(Pt 12):3477-3483.
36. Brown NR, Noble ME, Endicott JA, Garman EF, Wakatsuki S, Mitchell E, Rasmussen B, Hunt T, Johnson LN. The crystal structure of cyclin A. Structure 1995, 3(11):1235-1247. 10.1016/S0969-2126(01)00259-3, 8591034.
37. Li Z, Lee JH, Chu F, Burlingame AL, Gunzl A, Wang CC. Identification of a novel chromosomal passenger complex and its unique localization during cytokinesis in Trypanosoma brucei. PLoS One 2008, 3(6):e2354. 10.1371/journal.pone.0002354, 2396291, 18545648.
38. Tyler KM, Higgs PG, Matthews KR, Gull K. Limitation of Trypanosoma brucei parasitaemia results from density-dependent parasite differentiation and parasite killing by the host immune response. Proc Biol Sci 2001, 268(1482):2235-2243. 10.1098/rspb.2001.1794, 1088871, 11674871.
39. Tu X, Wang CC. Coupling of posterior cytoskeletal morphogenesis to the G1/S transition in the Trypanosoma brucei cell cycle. Mol Biol Cell 2005, 16(1):97-105. 10.1091/mbc.E04-05-0368, 539155, 15525678.
40. Sherr CJ. D-type cyclins. Trends Biochem Sci 1995, 20(5):187-190. 10.1016/S0968-0004(00)89005-2, 7610482.
41. Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999, 13(12):1501-1512. 10.1101/gad.13.12.1501, 10385618.
42. Diffley JF. Regulation of early events in chromosome replication. Curr Biol 2004, 14(18):R778-786. 10.1016/j.cub.2004.09.019, 15380092.
43. Boonstra J. Progression through the G1-phase of the on-going cell cycle. J Cell Biochem 2003, 90(2):244-252. 10.1002/jcb.10617, 14505341.
44. Miller ME, Cross FR. Cyclin specificity: how many wheels do you need on a unicycle?. J Cell Sci 2001, 114(Pt 10):1811-1820.
45. Yang J, Kornbluth S. All aboard the cyclin train: subcellular trafficking of cyclins and their CDK partners. Trends Cell Biol 1999, 9(6):207-210. 10.1016/S0962-8924(99)01577-9, 10354564.
46. Li Z, Wang CC. Changing roles of aurora-B kinase in two life cycle stages of Trypanosoma brucei. Eukaryot Cell 2006, 5(7):1026-1035. 10.1128/EC.00129-06, 1489291, 16835447.
47. Tu X, Mancuso J, Cande WZ, Wang CC. Distinct cytoskeletal modulation and regulation of G1-S transition in the two life stages of Trypanosoma brucei. J Cell Sci 2005, 118(Pt 19):4353-4364. 10.1242/jcs.02567, 16144864.