-
1
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J. Clin. 59(4), 225-249 (2009).
-
(2009)
CA Cancer J. Clin.
, vol.59
, Issue.4
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
2
-
-
17544401946
-
A new American Joint Committee on Cancer staging system for cutaneous melanoma
-
Balch CM, Buzaid AC, Atkins MB et al. A new American Joint Committee on Cancer staging system for cutaneous melanoma. Cancer 88(6), 1484-1491 (2000).
-
(2000)
Cancer
, vol.88
, Issue.6
, pp. 1484-1491
-
-
Balch, C.M.1
Buzaid, A.C.2
Atkins, M.B.3
-
3
-
-
0035881074
-
Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma
-
Balch CM, Buzaid AC, Soong SJ et al. Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J. Clin. Oncol. 19(16), 3635-3648 (2001).
-
(2001)
J. Clin. Oncol.
, vol.19
, Issue.16
, pp. 3635-3648
-
-
Balch, C.M.1
Buzaid, A.C.2
Soong, S.J.3
-
4
-
-
10744230605
-
New TNM melanoma staging system: Linking biology and natural history to clinical outcomes. A new American Joint Committee on Cancer staging system for cutaneous melanoma
-
Balch CM, Buzaid AC, Soong SJ et al. New TNM melanoma staging system: linking biology and natural history to clinical outcomes. A new American Joint Committee on Cancer staging system for cutaneous melanoma. Cancer 21(1), 43-52 (2003).
-
(2003)
Cancer
, vol.21
, Issue.1
, pp. 43-52
-
-
Balch, C.M.1
Buzaid, A.C.2
Soong, S.J.3
-
5
-
-
33846805852
-
Melanoma immunology: Past, present and future
-
DOI 10.1097/CCO.0b013e32801497d7, PII 0000162220070300000010
-
Parmiani G, Castelli C, Santinami M, Rivoltini L. Melanoma immunology: past, present and future. Curr. Opin. Oncol. 19(2), 121-127 (2007). • Review on immunology of melanoma and its possible applications in terms of immunotherapy. (Pubitemid 46204351)
-
(2007)
Current Opinion in Oncology
, vol.19
, Issue.2
, pp. 121-127
-
-
Parmiani, G.1
Castelli, C.2
Santinami, M.3
Rivoltini, L.4
-
6
-
-
0035865364
-
Isolation of a new melanoma antigen, MART-2, containing a mutated epitope recognized by autologous tumor-infiltrating T lymphocytes
-
Kawakami Y, Wang X, Shofuda T et al. Isolation of a new melanoma antigen, MART-2, containing a mutated epitope recognized by autologous tumor-infiltrating T lymphocytes. J. Immunol. 166(4), 2871-2877 (2001). (Pubitemid 32173530)
-
(2001)
Journal of Immunology
, vol.166
, Issue.4
, pp. 2871-2877
-
-
Kawakami, Y.1
Wang, X.2
Shofuda, T.3
Sumimoto, H.4
Tupesis, J.P.5
Fitzgerald, E.6
Rosenberg, S.A.7
-
7
-
-
0141955112
-
Human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of mela
-
Rivoltini L, Castelli C, Carrabba M et al. Human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of mela. J. Immunol. 171(7), 3467-3474 (2003).
-
(2003)
J. Immunol.
, vol.171
, Issue.7
, pp. 3467-3474
-
-
Rivoltini, L.1
Castelli, C.2
Carrabba, M.3
-
8
-
-
34748849509
-
Vaccine therapy for melanoma: Current status and future directions
-
Review on vaccine use in melanoma
-
Terando AM, Faries MB, Morton DL. Vaccine therapy for melanoma: current status and future directions. Vaccine 25(Suppl. 2), B4-B16 (2007). • Review on vaccine use in melanoma.
-
(2007)
Vaccine
, vol.25
, Issue.SUPPL. 2
-
-
Terando, A.M.1
Faries, M.B.2
Morton, D.L.3
-
9
-
-
3843113670
-
Re-evaluating the role of dacarbazine in metastatic melanoma: What have we learned in 30 years?
-
Eggermont AM, Kirkwood JM. Re-evaluating the role of dacarbazine in metastatic melanoma: what have we learned in 30 years? Eur. J. Cancer 40(12), 1825-1836 (2004).
-
(2004)
Eur. J. Cancer
, vol.40
, Issue.12
, pp. 1825-1836
-
-
Eggermont, A.M.1
Kirkwood, J.M.2
-
10
-
-
0003077969
-
Cutaneous melanoma
-
(5th Edition). DeVita VT (Ed.). Lippincott, PA, USA
-
Balch CM, Kirkwood J, Reintgen DS. Cutaneous melanoma. In: Cancer: Principles and Practice of Oncology (5th Edition). DeVita VT (Ed.). Lippincott, PA, USA, 1947-1994 (1997).
-
(1997)
Cancer: Principles and Practice of Oncology
, pp. 1947-1994
-
-
Balch, C.M.1
Kirkwood, J.2
Reintgen, D.S.3
-
11
-
-
0033989205
-
Randomized Phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
-
Middleton MR, Grob JJ, Aaronson N et al. Randomized Phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma. J. Clin. Oncol. 18(1), 158-166 (2000).
-
(2000)
J. Clin. Oncol.
, vol.18
, Issue.1
, pp. 158-166
-
-
Middleton, M.R.1
Grob, J.J.2
Aaronson, N.3
-
12
-
-
33644811013
-
Temozolomide in combination with interferon-a versus temozolomide alone in patients with advanced metastatic melanoma: A randomized, Phase III, multicenter study from the Dermatologic Cooperative Oncology Group
-
Kaufmann R, Spieth K, Leiter U et al. Temozolomide in combination with interferon-a versus temozolomide alone in patients with advanced metastatic melanoma: a randomized, Phase III, multicenter study from the Dermatologic Cooperative Oncology Group. J. Clin. Oncol. 23(35), 9001-9007 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.35
, pp. 9001-9007
-
-
Kaufmann, R.1
Spieth, K.2
Leiter, U.3
-
13
-
-
0028608027
-
A Phase II study of the sequential administration of dacarbazine and fotemustine in the treatment of cerebral metastases from malignant melanoma
-
Chang J, Atkinson H, A'Hern R, Lorentzos A, Gore ME. A Phase II study of the sequential administration of dacarbazine and fotemustine in the treatment of cerebral metastases from malignant melanoma. Eur. J. Cancer 30A(14), 2093-2095 (1994).
-
(1994)
Eur. J. Cancer
, vol.30 A
, Issue.14
, pp. 2093-2095
-
-
Chang, J.1
Atkinson, H.2
A'Hern, R.3
Lorentzos, A.4
Gore, M.E.5
-
14
-
-
0031805725
-
Phase III trial of dacarbazine versus dacarbazine with interferon α-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon α-2b and tamoxifen in patients with metastatic malignant melanoma: An Eastern Cooperative oncology Group Study
-
Falkson CI, Ibrahim J, Kirkwood JM, Coates AS, Atkins MB, Blum RH. Phase III trial of dacarbazine versus dacarbazine with interferon α-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon α-2b and tamoxifen in patients with metastatic malignant melanoma: an Eastern Cooperative Oncology Group study. J. Clin. Oncol. 16(5), 1743-1751 (1998). (Pubitemid 28234718)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.5
, pp. 1743-1751
-
-
Falkson, C.I.1
Ibrahim, J.2
Kirkwood, J.M.3
Coates, A.S.4
Atkins, M.B.5
Blum, R.H.6
-
15
-
-
0026655673
-
Fotemustine: An overview of its clinical activity in disseminated malignant melanoma
-
Khayat D, Avril MF, Gerard B, Bertrand P, Bizzari JP, Cour V. Fotemustine: an overview of its clinical activity in disseminated malignant melanoma. Melanoma Res. 2(3), 147-151 (1992).
-
(1992)
Melanoma Res.
, vol.2
, Issue.3
, pp. 147-151
-
-
Khayat, D.1
Avril, M.F.2
Gerard, B.3
Bertrand, P.4
Bizzari, J.P.5
Cour, V.6
-
16
-
-
1842562211
-
Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: A Phase III study
-
Avril MF, Aamdal S, Grob JJ et al. Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a Phase III study. J. Clin. Oncol. 22(6), 1118-1125 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.6
, pp. 1118-1125
-
-
Avril, M.F.1
Aamdal, S.2
Grob, J.J.3
-
17
-
-
7244229992
-
The role of taxanes in the treatment of metastatic melanoma
-
DOI 10.1097/00008390-200410000-00013
-
Gogas H, Bafaloukos D, Bedikian AY. The role of taxanes in the treatment of metastatic melanoma. Melanoma Res. 14(5), 415-420 (2004). (Pubitemid 39431239)
-
(2004)
Melanoma Research
, vol.14
, Issue.5
, pp. 415-420
-
-
Gogas, H.1
Bafaloukos, D.2
Bedikian, A.Y.3
-
18
-
-
33745134735
-
Drug evaluation: STA-4783 - Enhancing taxane efficacy by induction of Hsp70
-
Gehrmann M. Drug evaluation: STA-4783 - enhancing taxane efficacy by induction of Hsp70. Curr. Opin. Investig. Drugs 7(6), 574-580 (2006). (Pubitemid 43891037)
-
(2006)
Current Opinion in Investigational Drugs
, vol.7
, Issue.6
, pp. 574-580
-
-
Gehrmann, M.1
-
19
-
-
0020062969
-
Cisplatin hydration with and without mannitol diuresis in refractory disseminated malignant melanoma: A southwest oncology group study
-
Al Sarraf M, Fletcher W, Oishi N et al. Cisplatin hydration with and without mannitol diuresis in refractory disseminated malignant melanoma: a southwest oncology group study. Cancer Treat. Rep. 66(1), 31-35 (1982). (Pubitemid 12254661)
-
(1982)
Cancer Treatment Reports
, vol.66
, Issue.1
, pp. 31-35
-
-
Al-Sarraf, M.1
Flectcher, W.2
Oishi, N.3
-
20
-
-
0023258489
-
WR-2721 and high-dose cisplatin: An active combination in the treatment of metastatic melanoma
-
Glover D, Glick JH, Weiler C, Fox K, Guerry D. WR-2721 and high-dose cisplatin: an active combination in the treatment of metastatic melanoma. J. Clin. Oncol. 5(4), 574-578 (1987). (Pubitemid 17062494)
-
(1987)
Journal of Clinical Oncology
, vol.5
, Issue.4
, pp. 574-578
-
-
Glover, D.1
Glick, J.H.2
Weiler, C.3
-
21
-
-
0030925810
-
The treatment of metastatic melanoma with chemotherapy and biologics
-
Atkins MB. The treatment of metastatic melanoma with chemotherapy and biologics. Curr. Opin. Oncol. 9(2), 205-213 (1997).
-
(1997)
Curr. Opin. Oncol.
, vol.9
, Issue.2
, pp. 205-213
-
-
Atkins, M.B.1
-
22
-
-
0033135342
-
A Phase III randomized trial of dacarbazine and carboplatin with and without tamoxifen in the treatment of patients with metastatic melanoma
-
Agarwala SS, Ferri W, Gooding W, Kirkwood JM. A Phase III randomized trial of dacarbazine and carboplatin with and without tamoxifen in the treatment of patients with metastatic melanoma. Cancer 85(9), 1979-1984 (1999).
-
(1999)
Cancer
, vol.85
, Issue.9
, pp. 1979-1984
-
-
Agarwala, S.S.1
Ferri, W.2
Gooding, W.3
Kirkwood, J.M.4
-
23
-
-
0028218050
-
Multicenter randomized trial of dacarbazine alone or in combination with two different doses and schedules of interferon α-2a in the treatment of advanced melanoma
-
Bajetta E, Di Leo A, Zampino MG et al. Multicenter randomized trial of dacarbazine alone or in combination with two different doses and schedules of interferon α-2a in the treatment of advanced melanoma. J. Clin. Oncol. 12(4), 806-811 (1994).
-
(1994)
J. Clin. Oncol.
, vol.12
, Issue.4
, pp. 806-811
-
-
Bajetta, E.1
Di Leo, A.2
Zampino, M.G.3
-
24
-
-
0032858487
-
Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma
-
Chapman PB, Einhorn LH, Meyers ML et al. Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma. J. Clin. Oncol. 17(9), 2745-2751 (1999).
-
(1999)
J. Clin. Oncol.
, vol.17
, Issue.9
, pp. 2745-2751
-
-
Chapman, P.B.1
Einhorn, L.H.2
Meyers, M.L.3
-
25
-
-
0342894822
-
Interferon alfa-2a and interleukin-2 with or without cisplatin in metastatic melanoma: A randomized trial of the European organization for research and treatment of cancer melanoma cooperative group
-
Keilholz U, Goey SH, Punt CJ et al. Interferon α-2a and interleukin-2 with or without cisplatin in metastatic melanoma: a randomized trial of the European Organization for Research and Treatment of Cancer Melanoma Cooperative Group. J. Clin. Oncol. 15(7), 2579-2588 (1997). (Pubitemid 27289888)
-
(1997)
Journal of Clinical Oncology
, vol.15
, Issue.7
, pp. 2579-2588
-
-
Keilholz, U.1
Goey, S.H.2
Punt, C.J.A.3
Proebstle, T.M.4
Salzmann, R.5
Scheibenbogen, C.6
Schadendorf, D.7
Lienard, D.8
Enk, A.9
Dummer, R.10
Hantich, B.11
Geueke, A.-M.12
Eggermont, A.M.M.13
-
26
-
-
0032976897
-
Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon α-2b
-
Rosenberg SA, Yang JC, Schwartzentruber DJ et al. Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon α-2b. J. Clin. Oncol. 17(3), 968-975 (1999).
-
(1999)
J. Clin. Oncol.
, vol.17
, Issue.3
, pp. 968-975
-
-
Rosenberg, S.A.1
Yang, J.C.2
Schwartzentruber, D.J.3
-
27
-
-
8944261598
-
Randomized, double-blind, placebo-controlled trial comparing the response rates of carmustine, dacarbazine, and cisplatin with and without tamoxifen in patients with metastatic melanoma
-
National Cancer Institute of Canada Clinical Trials Group
-
Rusthoven JJ, Quirt IC, Iscoe NA et al. Randomized, double-blind, placebo-controlled trial comparing the response rates of carmustine, dacarbazine, and cisplatin with and without tamoxifen in patients with metastatic melanoma. National Cancer Institute of Canada Clinical Trials Group. J. Clin. Oncol. 14(7), 2083-2090 (1996).
-
(1996)
J. Clin. Oncol.
, vol.14
, Issue.7
, pp. 2083-2090
-
-
Rusthoven, J.J.1
Quirt, I.C.2
Iscoe, N.A.3
-
28
-
-
0021876972
-
Comparison of intramuscular and intravenous recombinant α-2 interferon in melanoma and other cancers
-
Kirkwood JM, Ernstoff MS, Davis CA, Reiss M, Ferraresi R, Rudnick SA. Comparison of intramuscular and intravenous recombinant α-2 interferon in melanoma and other cancers. Ann. Intern. Med. 103(1), 32-36 (1985).
-
(1985)
Ann. Intern. Med.
, vol.103
, Issue.1
, pp. 32-36
-
-
Kirkwood, J.M.1
Ernstoff, M.S.2
Davis, C.A.3
Reiss, M.4
Ferraresi, R.5
Rudnick, S.A.6
-
29
-
-
0022379919
-
Melanoma: Therapeutic options with recombinant interferons
-
Kirkwood JM, Ernstoff M. Melanoma: therapeutic options with recombinant interferons. Semin. Oncol. 12(4 Suppl. 5), 7-12 (1985). (Pubitemid 16184752)
-
(1985)
Seminars in Oncology
, vol.12
, Issue.4 SUPPL. 5
, pp. 7-12
-
-
Kirkwood, J.M.1
Ernstoff, M.2
-
30
-
-
0034088027
-
High- and low-dose interferon α-2b in high-risk melanoma: First ana lysis of intergroup trial E1690/S9111/C9190
-
Kirkwood JM, Ibrahim JG, Sondak VK et al. High- and low-dose interferon α-2b in high-risk melanoma: first ana lysis of intergroup trial E1690/S9111/C9190. J. Clin. Oncol. 18(12), 2444-2458 (2000).
-
(2000)
J. Clin. Oncol.
, vol.18
, Issue.12
, pp. 2444-2458
-
-
Kirkwood, J.M.1
Ibrahim, J.G.2
Sondak, V.K.3
-
31
-
-
0035339880
-
High-dose interferon α-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: Results of intergroup trial E1694/S9512/C509801
-
Kirkwood JM, Ibrahim JG, Sosman JA et al. High-dose interferon α-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. J. Clin. Oncol. 19(9), 2370-2380 (2001).
-
(2001)
J. Clin. Oncol.
, vol.19
, Issue.9
, pp. 2370-2380
-
-
Kirkwood, J.M.1
Ibrahim, J.G.2
Sosman, J.A.3
-
32
-
-
0033024863
-
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Ana lysis of 270 patients treated between 1985 and 1993
-
Atkins MB, Lotze MT, Dutcher JP et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: ana lysis of 270 patients treated between 1985 and 1993. J. Clin. Oncol. 17(7), 2105-2116 (1999).
-
(1999)
J. Clin. Oncol.
, vol.17
, Issue.7
, pp. 2105-2116
-
-
Atkins, M.B.1
Lotze, M.T.2
Dutcher, J.P.3
-
33
-
-
0033848628
-
High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: Long-term survival update
-
Atkins MB, Kunkel L, Sznol M, Rosenberg SA. High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update. Cancer J. Sci. Am. 6(Suppl. 1), S11-S14 (2000). (Pubitemid 30117631)
-
(2000)
Cancer Journal from Scientific American
, vol.6
, Issue.SUPPL. 1
-
-
Atkins, M.B.1
Kunkel, L.2
Sznol, M.3
Rosenberg, S.A.4
-
34
-
-
0024544021
-
A phase II study of interleukin-2 and lymphokine-activated killer cells in patients with metastatic malignant melanoma
-
Dutcher JP, Creekmore S, Weiss GR et al. A Phase II study of interleukin-2 and lymphokine-activated killer cells in patients with metastatic malignant melanoma. J. Clin. Oncol. 7(4), 477-485 (1989). (Pubitemid 19098143)
-
(1989)
Journal of Clinical Oncology
, vol.7
, Issue.4
, pp. 477-485
-
-
Dutcher, J.P.1
Creekmore, S.2
Weiss, G.R.3
Margolin, K.4
Markowitz, A.B.5
Roper, M.6
Parkinson, D.7
Ciobanu, N.8
Fisher, R.I.9
Boldt, D.H.10
Doroshow, J.H.11
Rayner, A.A.12
Hawkins, M.13
Atkins, M.14
-
35
-
-
0025085675
-
Interleukin-2 therapy in patients with metastatic malignant melanoma: A Phase II study
-
Parkinson DR, Abrams JS, Wiernik PH et al. Interleukin-2 therapy in patients with metastatic malignant melanoma: a Phase II study. J. Clin. Oncol. 8(10), 1650-1656 (1990).
-
(1990)
J. Clin. Oncol.
, vol.8
, Issue.10
, pp. 1650-1656
-
-
Parkinson, D.R.1
Abrams, J.S.2
Wiernik, P.H.3
-
36
-
-
0028266553
-
Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2
-
Rosenberg SA, Yang JC, Topalian SL et al. Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2. JAMA 271(12), 907-913 (1994).
-
(1994)
JAMA
, vol.271
, Issue.12
, pp. 907-913
-
-
Rosenberg, S.A.1
Yang, J.C.2
Topalian, S.L.3
-
37
-
-
0029906912
-
Treatment of metastatic melanoma with combined chemotherapy containing cisplatin, vinblastine and dacarbazine (CVD) and biotherapy using interleukin-2 and interferon
-
Legha SS, Ring S, Bedikian A et al. Treatment of metastatic melanoma with combined chemotherapy containing cisplatin, vinblastine and dacarbazine (CVD) and biotherapy using interleukin-2 and interferon-α. Ann. Oncol. 7(8), 827-835 (1996). (Pubitemid 26345874)
-
(1996)
Annals of Oncology
, vol.7
, Issue.8
, pp. 827-835
-
-
Legha, S.S.1
Ring, S.2
Bedikian, A.3
Plager, C.4
Eton, O.5
Buzaid, A.C.6
Papadopoulos, N.7
-
38
-
-
0030937204
-
Durable complete responses in metastatic melanoma treated with interleukin-2 in combination with interferon α and chemotherapy
-
Legha SS. Durable complete responses in metastatic melanoma treated with interleukin-2 in combination with interferon α and chemotherapy. Semin. Oncol. 24(1 Suppl. 4), S39-S43 (1997).
-
(1997)
Semin. Oncol.
, vol.24
, Issue.1 SUPPL. 4
-
-
Legha, S.S.1
-
39
-
-
0031424902
-
Development and results of biochemotherapy in metastatic melanoma: The University of Texas M.D. anderson cancer center experience
-
Legha SS, Ring S, Eton O, Bedikian A, Plager C, Papadopoulos N. Development and results of biochemotherapy in metastatic melanoma: the University of Texas M.D. Anderson Cancer Center experience. Cancer J. Sci. Am. 3(Suppl. 1), S9-S15 (1997). (Pubitemid 127698055)
-
(1997)
Cancer Journal
, vol.3
, Issue.1 SUPPL.
-
-
Legha, S.S.1
Ring, S.2
Eton, O.3
Bedikian, A.4
Plager, C.5
Papadopoulos, N.6
-
40
-
-
0031805726
-
Development of a biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, dacarbazine, interferon alfa, and interleukin-2 for patients with metastatic melanoma
-
Legha SS, Ring S, Eton O et al. Development of a biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, dacarbazine, interferon α, and interleukin-2 for patients with metastatic melanoma. J. Clin. Oncol. 16(5), 1752-1759 (1998). (Pubitemid 28234719)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.5
, pp. 1752-1759
-
-
Legha, S.S.1
Ring, S.2
Eton, O.3
Bedikian, A.4
Buzaid, A.C.5
Plager, C.6
Papadopoulos, N.7
-
41
-
-
0037089629
-
Sequential biochemotherapy versus chemotherapy for metastatic melanoma: Results from a phase III randomized trial
-
DOI 10.1200/JCO.2002.07.044
-
Eton O, Legha SS, Bedikian AY et al. Sequential biochemotherapy versus chemotherapy for metastatic melanoma: results from a Phase III randomized trial. J. Clin. Oncol. 20(8), 2045-2052 (2002). (Pubitemid 34408794)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.8
, pp. 2045-2052
-
-
Eton, O.1
Legha, S.S.2
Bedikian, A.Y.3
Lee, J.J.4
Buzaid, A.C.5
Hodges, C.6
Ring, S.E.7
Papadopoulos, N.E.8
Plager, C.9
East, M.J.10
Zhan, F.11
Benjamin, R.S.12
-
42
-
-
53949108399
-
Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon α-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): A trial coordinated by the Eastern Cooperative Oncology Group
-
Atkins MB, Hsu J, Lee S et al. Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon α-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): a trial coordinated by the Eastern Cooperative Oncology Group. J. Clin. Oncol. 26(35), 5748-5754 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.35
, pp. 5748-5754
-
-
Atkins, M.B.1
Hsu, J.2
Lee, S.3
-
43
-
-
0038153907
-
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
-
Phan GQ, Yang JC, Sherry RM et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc. Natl Acad. Sci. USA 100(14), 8372-8377 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.14
, pp. 8372-8377
-
-
Phan, G.Q.1
Yang, J.C.2
Sherry, R.M.3
-
44
-
-
32644467549
-
Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206
-
DOI 10.1200/JCO.2005.01.109
-
Ribas A, Camacho LH, Lopez-Berestein G et al. Antitumor activity in melanoma and anti-self responses in a Phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP- 675,206. J. Clin. Oncol. 23(35), 8968-8977 (2005). (Pubitemid 46217464)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.35
, pp. 8968-8977
-
-
Ribas, A.1
Camacho, L.H.2
Lopez-Berestein, G.3
Pavlov, D.4
Bulanhagui, C.A.5
Millham, R.6
Comin-Anduix, B.7
Reuben, J.M.8
Seja, E.9
Parker, C.A.10
Sharma, A.11
Glaspy, J.A.12
Gomez-Navarro, J.13
-
45
-
-
27844458057
-
Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: A phase I/II study
-
DOI 10.1245/ASO.2005.03.536
-
Maker AV, Phan GQ, Attia P et al. Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a Phase I/II study. Ann. Surg. Oncol. 12(12), 1005-1016 (2005). (Pubitemid 41660676)
-
(2005)
Annals of Surgical Oncology
, vol.12
, Issue.12
, pp. 1005-1016
-
-
Maker, A.V.1
Phan, G.Q.2
Attia, P.3
Yang, J.C.4
Sherry, R.M.5
Topalian, S.L.6
Kammula, U.S.7
Royal, R.E.8
Haworth, L.R.9
Levy, C.10
Kleiner, D.11
Mavroukakis, S.A.12
Yellin, M.13
Rosenberg, S.A.14
-
46
-
-
20044395957
-
Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and montanide ISA 51 for patients with resected stages III and IV melanoma
-
DOI 10.1200/JCO.2005.01.128
-
Sanderson K, Scotland R, Lee P et al. Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma. J. Clin. Oncol. 23(4), 741-750 (2005). (Pubitemid 46224173)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.4
, pp. 741-750
-
-
Sanderson, K.1
Scotland, R.2
Lee, P.3
Liu, D.4
Groshen, S.5
Snively, J.6
Sian, S.7
Nichol, G.8
Davis, T.9
Keler, T.10
Yellin, M.11
Weber, J.12
-
47
-
-
0036194868
-
Immunotherapy for melanoma
-
Kim CJ, Dessureault S, Gabrilovich D, Reintgen DS, Slingluff CL Jr. Immunotherapy for melanoma. Cancer Control 9(1), 22-30 (2002).
-
(2002)
Cancer Control
, vol.9
, Issue.1
, pp. 22-30
-
-
Kim, C.J.1
Dessureault, S.2
Gabrilovich, D.3
Reintgen, D.S.4
Slingluff Jr., C.L.5
-
48
-
-
0018223396
-
Specific immunotherapy of established visceral micrometastases by BCG-tumor cell vaccine alone or as an adjunct to surgery
-
Hanna MG Jr, Peters LC. Specific immunotherapy of established visceral micrometastases by BCG-tumor cell vaccine alone or as an adjunct to surgery. Cancer 42(6), 2613-2625 (1978).
-
(1978)
Cancer
, vol.42
, Issue.6
, pp. 2613-2625
-
-
Hanna Jr., M.G.1
Peters, L.C.2
-
49
-
-
0020606837
-
Synergistic effects of active specific immunotherapy and chemotherapy in guinea pigs with disseminated cancer
-
Key ME, Brandhorst JS, Hanna MG Jr. Synergistic effects of active specific immunotherapy and chemotherapy in guinea pigs with disseminated cancer. J. Immunol. 130(6), 2987-2992 (1983).
-
(1983)
J. Immunol.
, vol.130
, Issue.6
, pp. 2987-2992
-
-
Key, M.E.1
Brandhorst, J.S.2
Hanna Jr., M.G.3
-
50
-
-
0018772239
-
Preparation of immunotherapeutic autologous tumor cell vaccines from solid tumors
-
Peters LC, Brandhorst JS, Hanna MG Jr. Preparation of immunotherapeutic autologous tumor cell vaccines from solid tumors. Cancer Res. 39(4), 1353-1360 (1979).
-
(1979)
Cancer Res.
, vol.39
, Issue.4
, pp. 1353-1360
-
-
Peters, L.C.1
Brandhorst, J.S.2
Hanna Jr., M.G.3
-
51
-
-
0033991158
-
Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance
-
Marincola FM, Jaffee EM, Hicklin DJ, Ferrone S. Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv. Immunol. 74, 181-273 (2000).
-
(2000)
Adv. Immunol.
, vol.74
, pp. 181-273
-
-
Marincola, F.M.1
Jaffee, E.M.2
Hicklin, D.J.3
Ferrone, S.4
-
53
-
-
0031941423
-
Vaccination of melanoma patients with pep
-
Nestle FO, Alijagic S, Gilliet M et al. Vaccination of melanoma patients with pep. Nat. Med. 4(3), 328-332 (1998).
-
(1998)
Nat. Med.
, vol.4
, Issue.3
, pp. 328-332
-
-
Nestle, F.O.1
Alijagic, S.2
Gilliet, M.3
-
54
-
-
0033405438
-
Vaccination with Mage-3A1 peptide-pulsed nature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma
-
DOI 10.1084/jem.190.11.1669
-
Thurner B, Haendle I, Roder C et al. Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J. Exp. Med. 190(11), 1669-1678 (1999). (Pubitemid 30002348)
-
(1999)
Journal of Experimental Medicine
, vol.190
, Issue.11
, pp. 1669-1678
-
-
Thurner, B.1
Haendle, I.2
Roder, C.3
Dieckmann, D.4
Keikavoussi, P.5
Jonuleit, H.6
Bender, A.7
Maczek, C.8
Schreiner, D.9
Von Den Driesch, P.10
Brocker, E.B.11
Steinman, R.M.12
Enk, A.13
Kampgen, E.14
Schuler, G.15
-
55
-
-
33645325115
-
Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: A randomized Phase III trial of the DC study group of the DeCOG
-
Schadendorf D, Ugurel S, Schuler- Thurner B et al. Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized Phase III trial of the DC study group of the DeCOG. Ann. Oncol. 17(4), 563-570 (2006).
-
(2006)
Ann. Oncol.
, vol.17
, Issue.4
, pp. 563-570
-
-
Schadendorf, D.1
Ugurel, S.2
Schuler-Thurner, B.3
-
56
-
-
39749186213
-
Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: The C-100-21 Study Group
-
First Phase III clinical trial on the use of Oncophage® in metastatic melanoma patients
-
Testori A, Richards J, Whitman E et al. Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group. J. Clin. Oncol. 26(6), 955-962 (2008). •• First Phase III clinical trial on the use of Oncophage® in metastatic melanoma patients.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.6
, pp. 955-962
-
-
Testori, A.1
Richards, J.2
Whitman, E.3
-
58
-
-
0036079798
-
Technology evaluation: Allovectin-7, Vical
-
Galanis E. Technology evaluation: Allovectin-7, Vical. Curr. Opin. Mol. Ther. 4(1), 80-87 (2002).
-
(2002)
Curr. Opin. Mol. Ther.
, vol.4
, Issue.1
, pp. 80-87
-
-
Galanis, E.1
-
59
-
-
33745714225
-
Association of antigen-processing machinery and HLA antigen phenotype of melanoma cells with survival in American Joint Committee on Cancer stage III and IV melanoma patients
-
Anichini A, Mortarini R, Nonaka D et al. Association of antigen-processing machinery and HLA antigen phenotype of melanoma cells with survival in American Joint Committee on Cancer stage III and IV melanoma patients. Cancer Res. 66(12), 6405-6411 (2006).
-
(2006)
Cancer Res.
, vol.66
, Issue.12
, pp. 6405-6411
-
-
Anichini, A.1
Mortarini, R.2
Nonaka, D.3
-
60
-
-
16844365788
-
+ regulatory T cells in immunological tolerance to self and non-self
-
+ regulatory T cells in immunological tolerance to self and non-self. Nat. Immunol. 6(4), 345-352 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, Issue.4
, pp. 345-352
-
-
Sakaguchi, S.1
-
61
-
-
0037217371
-
+ suppressor lymphocytes in the circulation of patients immunized against melanoma antigens
-
+ suppressor lymphocytes in the circulation of patients immunized against melanoma antigens. J. Immunother. 26(1), 85-93 (2003).
-
(2003)
J. Immunother.
, vol.26
, Issue.1
, pp. 85-93
-
-
Javia, L.R.1
Rosenberg, S.A.2
-
62
-
-
3142737258
-
high regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
-
high regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J. Immunol. 173(2), 1444-1453 (2004).
-
(2004)
J. Immunol.
, vol.173
, Issue.2
, pp. 1444-1453
-
-
Viguier, M.1
Lemaitre, F.2
Verola, O.3
-
63
-
-
33749488765
-
Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-β-mediated suppressive activity on T lymphocytes
-
DOI 10.1158/0008-5472.CAN-06-1819
-
Valenti R, Huber V, Filipazzi P et al. Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-β-mediated suppressive activity on T lymphocytes. Cancer Res. 66(18), 9290-9298 (2006). (Pubitemid 44521151)
-
(2006)
Cancer Research
, vol.66
, Issue.18
, pp. 9290-9298
-
-
Valenti, R.1
Huber, V.2
Filipazzi, P.3
Pilla, L.4
Sovena, G.5
Villa, A.6
Corbelli, A.7
Fais, S.8
Parmiani, G.9
Rivoltini, L.10
-
64
-
-
0037141153
-
Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles
-
DOI 10.1084/jem.20011624
-
Andreola G, Rivoltini L, Castelli C et al. Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J. Exp. Med. 195(10), 1303-1316 (2002). (Pubitemid 34564332)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.10
, pp. 1303-1316
-
-
Andreola, G.1
Rivoltini, L.2
Castelli, C.3
Huber, V.4
Perego, P.5
Deho, P.6
Squarcina, P.7
Accornero, P.8
Lozupone, F.9
Lugini, L.10
Stringaro, A.11
Molinari, A.12
Arancia, G.13
Gentile, M.14
Parmiani, G.15
Fais, S.16
-
65
-
-
33847258205
-
Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients
-
DOI 10.1093/annonc/mdl158
-
Parmiani G, Castelli C, Pilla L, Santinami M, Colombo MP, Rivoltini L. Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients. Ann. Oncol. 18(2), 226-232 (2007). (Pubitemid 46323086)
-
(2007)
Annals of Oncology
, vol.18
, Issue.2
, pp. 226-232
-
-
Parmiani, G.1
Castelli, C.2
Pilla, L.3
Santinami, M.4
Colombo, M.P.5
Rivoltini, L.6
-
66
-
-
0032101221
-
Heat shock proteins come of age: Primitive functions acquire new roles in an adaptive world
-
DOI 10.1016/S1074-7613(00)80570-1
-
Srivastava PK, Menoret A, Basu S, Binder RJ, McQuade KL. Heat shock proteins come of age: primitive functions acquire new roles in an adaptive world. Immunity 8(6), 657-665 (1998). (Pubitemid 28294512)
-
(1998)
Immunity
, vol.8
, Issue.6
, pp. 657-665
-
-
Srivastava, P.K.1
Menoret, A.2
Basu, S.3
Binder, R.J.4
McQuade, K.L.5
-
67
-
-
0028301079
-
Comparison of tumor-specific immunogenicities of stress-induced proteins gp96, hsp90, and hsp70
-
Udono H, Srivastava PK. Comparison of tumor-specific immunogenicities of stress-induced proteins gp96, hsp90, and hsp70. J. Immunol. 152(11), 5398-5403 (1994). (Pubitemid 24152988)
-
(1994)
Journal of Immunology
, vol.152
, Issue.11
, pp. 5398-5403
-
-
Udono, H.1
Srivastava, P.K.2
-
68
-
-
5144225454
-
Therapeutic cancer vaccines: Using unique antigens
-
Lewis JJ. Therapeutic cancer vaccines: using unique antigens. Proc. Natl Acad. Sci. USA 101(Suppl. 2), 14653-14656 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.SUPPL. 2
, pp. 14653-14656
-
-
Lewis, J.J.1
-
69
-
-
0028979675
-
A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides
-
Suto R, Srivastava PK. A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides. Science 269(5230), 1585-1588 (1995).
-
(1995)
Science
, vol.269
, Issue.5230
, pp. 1585-1588
-
-
Suto, R.1
Srivastava, P.K.2
-
70
-
-
0035132104
-
Human heat shock protein 70 peptide complexes specifically activate antimelanoma t cells
-
Castelli C, Ciupitu AM, Rini F et al. Human heat shock protein 70 peptide complexes specifically activate antimelanoma T cells. Cancer Res. 61(1), 222-227 (2001). (Pubitemid 32095721)
-
(2001)
Cancer Research
, vol.61
, Issue.1
, pp. 222-227
-
-
Castelli, C.1
Ciupitu, A.T.2
Rini, F.3
Rivoltini, L.4
Mazzocchi, A.5
Kiessling, R.6
Parmiani, G.7
-
71
-
-
33646179699
-
Human T cell responses against melanoma
-
Boon T, Coulie PG, Van den Eynde BJ, van der Bruggen P. Human T cell responses against melanoma. Annu. Rev. Immunol. 24, 175-208 (2006).
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 175-208
-
-
Boon, T.1
Coulie, P.G.2
Van Den Eynde, B.J.3
Van Der Bruggen, P.4
-
72
-
-
0035070198
-
CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin
-
DOI 10.1016/S1074-7613(01)00111-X
-
Basu S, Binder RJ, Ramalingam T, Srivastava PK. CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin. Immunity 14(3), 303-313 (2001). (Pubitemid 32289294)
-
(2001)
Immunity
, vol.14
, Issue.3
, pp. 303-313
-
-
Basu, S.1
Binder, R.J.2
Ramalingam, T.3
Srivastava, P.K.4
-
73
-
-
0034252620
-
CD91: A receptor for heat shock protein gp96
-
Binder RJ, Han DK, Srivastava PK. CD91: a receptor for heat shock protein gp96. Nat. Immunol. 1(2), 151-155 (2000).
-
(2000)
Nat. Immunol.
, vol.1
, Issue.2
, pp. 151-155
-
-
Binder, R.J.1
Han, D.K.2
Srivastava, P.K.3
-
74
-
-
0037177833
-
HSP70 as endogenous stimulus of the toll/interleukin-1 receptor signal pathway
-
DOI 10.1074/jbc.M111204200
-
Vabulas RM, Ahmad-Nejad P, Ghose S, Kirschning CJ, Issels RD, Wagner H. HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway. J. Biol. Chem. 277(17), 15107-15112 (2002). (Pubitemid 34952589)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.17
, pp. 15107-15112
-
-
Vabulas, R.M.1
Ahmad-Nejad, P.2
Ghose, S.3
Kirschning, C.J.4
Issels, R.D.5
Wagner, H.6
-
75
-
-
0034113617
-
HSP70 stimulates cytokine production through a CD 14-dependant pathway, demonstrating its dual role as a chaperone and cytokine
-
DOI 10.1038/74697
-
Asea A, Kraeft SK, Kurt-Jones EA et al. HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat. Med. 6(4), 435-442 (2000). (Pubitemid 30208161)
-
(2000)
Nature Medicine
, vol.6
, Issue.4
, pp. 435-442
-
-
Asea, A.1
Kraeft, S.-K.2
Kurt-Jones, E.A.3
Stevenson, M.A.4
Chen, L.B.5
Finberg, R.W.6
Koo, G.C.7
Calderwood, S.K.8
-
76
-
-
0036569356
-
Cutting edge: CD91-independent cross-presentation of GRP94(gp96)- associated peptides
-
Berwin B, Hart JP, Pizzo SV, Nicchitta CV. Cutting edge: CD91-independent cross-presentation of GRP94(gp96)- associated peptides. J. Immunol. 168(9), 4282-4286 (2002). (Pubitemid 34441326)
-
(2002)
Journal of Immunology
, vol.168
, Issue.9
, pp. 4282-4286
-
-
Berwin, B.1
Hart, J.P.2
Pizzo, S.V.3
Nicchitta, C.V.4
-
77
-
-
16844371156
-
Immunotherapy for human cancer using heat shock protein-peptide complexes
-
Srivastava PK. Immunotherapy for human cancer using heat shock protein-peptide complexes. Curr. Oncol. Rep. 7(2), 104-108 (2005).
-
(2005)
Curr. Oncol. Rep.
, vol.7
, Issue.2
, pp. 104-108
-
-
Srivastava, P.K.1
-
78
-
-
0037087398
-
Heat shock proteins gp96 and hsp70 activate the release of nitric oxide by APCs
-
Panjwani NN, Popova L, Srivastava PK. Heat shock proteins gp96 and hsp70 activate the release of nitric oxide by APCs. J. Immunol. 168(6), 2997-3003 (2002). (Pubitemid 34211681)
-
(2002)
Journal of Immunology
, vol.168
, Issue.6
, pp. 2997-3003
-
-
Panjwani, N.N.1
Popova, L.2
Srivastava, P.K.3
-
79
-
-
0033976502
-
Heat shock proteins generate β-chemokines which function as innate adjuvants enhancing adaptive immunity
-
DOI 10.1002/1521-4141(200002)30:2<594::AID-IMMU594>3.0.CO;2-1
-
Lehner T, Bergmeier LA, Wang Y et al. Heat shock proteins generate β-chemokines which function as innate adjuvants enhancing adaptive immunity. Eur. J. Immunol. 30(2), 594-603 (2000). (Pubitemid 30098853)
-
(2000)
European Journal of Immunology
, vol.30
, Issue.2
, pp. 594-603
-
-
Lehner, T.1
Bergmeier, L.A.2
Wang, Y.3
Tao, L.4
Sing, M.5
Spallek, R.6
Van Der Zee, R.7
-
80
-
-
0033747044
-
Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway
-
Basu S, Binder RJ, Suto R, Anderson KM, Srivastava PK. Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway. Int. Immunol. 12(11), 1539-1546 (2000). (Pubitemid 30838184)
-
(2000)
International Immunology
, vol.12
, Issue.11
, pp. 1539-1546
-
-
Basu, S.1
Binder, R.J.2
Suto, R.3
Anderson, K.M.4
Srivastava, P.K.5
-
81
-
-
0033839045
-
The heat shock protein gp96 induces maturation of dendritic cells and down-regulation of its receptor
-
DOI 10.1002/1521-4141(2000)30:8<2211::AID-IMMU2211>3.0.CO;2-0
-
Singh-Jasuja H, Scherer HU, Hilf N et al. The heat shock protein gp96 induces maturation of dendritic cells and downregulation of its receptor. Eur. J. Immunol. 30(8), 2211-2215 (2000). (Pubitemid 30655760)
-
(2000)
European Journal of Immunology
, vol.30
, Issue.8
, pp. 2211-2215
-
-
Singh-Jasuja, H.1
Scherer, H.U.2
Hilf, N.3
Arnold-Schild, D.4
Rammensee, H.-G.5
Toes, R.E.M.6
Schild, H.7
-
82
-
-
38449103605
-
The heat shock protein HSP70 promotes mouse NK cell activity against tumors that express inducible NKG2D ligands
-
Elsner L, Muppala V, Gehrmann M et al. The heat shock protein HSP70 promotes mouse NK cell activity against tumors that express inducible NKG2D ligands. J. Immunol. 179(8), 5523-5533 (2007).
-
(2007)
J. Immunol.
, vol.179
, Issue.8
, pp. 5523-5533
-
-
Elsner, L.1
Muppala, V.2
Gehrmann, M.3
-
83
-
-
20944438543
-
Natural killer and NK-like T-cell activation in colorectal carcinoma patients treated with autologous tumor-derived heat shock protein 96
-
DOI 10.1158/0008-5472.CAN-04-3493
-
Pilla L, Squarcina P, Coppa J et al. Natural killer and NK-like T-cell activation in colorectal carcinoma patients treated with autologous tumor-derived heat shock protein 96. Cancer Res. 65(9), 3942-3949 (2005). (Pubitemid 40616377)
-
(2005)
Cancer Research
, vol.65
, Issue.9
, pp. 3942-3949
-
-
Pilla, L.1
Squarcina, P.2
Coppa, J.3
Mazzaferro, V.4
Huber, V.5
Pende, D.6
Maccalli, C.7
Sovena, G.8
Mariani, L.9
Castelli, C.10
Parmiani, G.11
Rivoltini, L.12
-
85
-
-
0037833596
-
Vaccination with heat shock protein-peptide complexes: From basic science to clinical applications
-
DOI 10.1586/14760584.2.3.369
-
Hoos A, Levey DL. Vaccination with heat shock protein-peptide complexes: from basic science to clinical applications. Expert Rev. Vaccines 2(3), 369-379 (2003). (Pubitemid 36713363)
-
(2003)
Expert Review of Vaccines
, vol.2
, Issue.3
, pp. 369-379
-
-
Hoos, A.1
Levey, D.L.2
-
86
-
-
4043126112
-
Heat shock protein-based cancer vaccines
-
DOI 10.1586/14760584.3.4.403
-
Oki Y, Younes A. Heat shock protein-based cancer vaccines. Expert Rev. Vaccines 3(4), 403-411 (2004). (Pubitemid 39061705)
-
(2004)
Expert Review of Vaccines
, vol.3
, Issue.4
, pp. 403-411
-
-
Oki, Y.1
Younes, A.2
-
87
-
-
0242413021
-
The challenges of bringing autologous HSP-based vaccines to commercial reality
-
Gordon NF, Clark BL. The challenges of bringing autologous HSP-based vaccines to commercial reality. Methods 32(1), 63-69 (2004).
-
(2004)
Methods
, vol.32
, Issue.1
, pp. 63-69
-
-
Gordon, N.F.1
Clark, B.L.2
-
88
-
-
0035219734
-
Methods of purification of heat shock protein-peptide complexes for use as vaccines against cancers and infectious diseases
-
Srivastava PK, Jaikaria NS. Methods of purification of heat shock protein-peptide complexes for use as vaccines against cancers and infectious diseases. Methods Mol. Biol. 156, 175-186 (2001).
-
(2001)
Methods Mol. Biol.
, vol.156
, pp. 175-186
-
-
Srivastava, P.K.1
Jaikaria, N.S.2
-
89
-
-
45849103058
-
Autologous tumor-derived heat-shock-protein peptide complex-96 (HSPPC-96) in patients with metastatic melanoma
-
Abstract 3463
-
Eton O. Autologous tumor-derived heat-shock-protein peptide complex-96 (HSPPC-96) in patients with metastatic melanoma. Proc. Am. Assoc. Cancer Res. (AACR) (2000) (Abstract 3463).
-
Proc. Am. Assoc. Cancer Res. (AACR) (2000)
-
-
Eton, O.1
-
90
-
-
0037108696
-
Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: Clinical and immunologic findings
-
Key report on the rationale supporting the Phase III clinical trial
-
Belli F, Testori A, Rivoltini L et al. Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: clinical and immunologic findings. J. Clin. Oncol. 20(20), 4169-4180 (2002). • Key report on the rationale supporting the Phase III clinical trial.
-
(2002)
J. Clin. Oncol.
, vol.20
, Issue.20
, pp. 4169-4180
-
-
Belli, F.1
Testori, A.2
Rivoltini, L.3
-
91
-
-
33646348754
-
A Phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-α in metastatic melanoma patients
-
Pilla L, Patuzzo R, Rivoltini L et al. A Phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-α in metastatic melanoma patients. Cancer Immunol. Immunother. 55(8), 958-968 (2006).
-
(2006)
Cancer Immunol. Immunother.
, vol.55
, Issue.8
, pp. 958-968
-
-
Pilla, L.1
Patuzzo, R.2
Rivoltini, L.3
-
92
-
-
0034328883
-
Immunotherapy of human cancer: Lessons from mice
-
Srivastava PK. Immunotherapy of human cancer: lessons from mice. Nat. Immunol. 1(5), 363-366 (2000).
-
(2000)
Nat. Immunol.
, vol.1
, Issue.5
, pp. 363-366
-
-
Srivastava, P.K.1
-
93
-
-
10744233222
-
Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer
-
Mazzaferro V, Coppa J, Carrabba MG et al. Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer. Clin. Cancer Res 9(9), 3235-3245 (2003).
-
(2003)
Clin. Cancer Res
, vol.9
, Issue.9
, pp. 3235-3245
-
-
Mazzaferro, V.1
Coppa, J.2
Carrabba, M.G.3
-
94
-
-
4043100909
-
Autologous leukocyte-derived heat shock protein 70-peptide complex as a vaccine for chronic myelogenous leukemia in chronic phase: An updated Phase I study
-
Li Z, Qiao Y, Laska E et al. Autologous leukocyte-derived heat shock protein 70-peptide complex as a vaccine for chronic myelogenous leukemia in chronic phase: an updated Phase I study. Blood 102, 911a (2003).
-
(2003)
Blood
, vol.102
-
-
Li, Z.1
Qiao, Y.2
Laska, E.3
-
95
-
-
0037089672
-
Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: Impact of HLA class I antigen expression on outcome
-
Sosman JA, Unger JM, Liu PY et al. Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: impact of HLA class I antigen expression on outcome. J. Clin. Oncol. 20(8), 2067-2075 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, Issue.8
, pp. 2067-2075
-
-
Sosman, J.A.1
Unger, J.M.2
Liu, P.Y.3
-
96
-
-
22544445236
-
Association of CTLA4 polymorphism with regulatory T cell frequency
-
DOI 10.1002/eji.200526168
-
Atabani SF, Thio CL, Divanovic S et al. Association of CTLA4 polymorphism with regulatory T cell frequency. Eur. J. Immunol. 35(7), 2157-2162 (2005). (Pubitemid 41015054)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.7
, pp. 2157-2162
-
-
Atabani, S.F.1
Thio, C.L.2
Divanovic, S.3
Trompette, A.4
Belkaid, Y.5
Thomas, D.L.6
Karp, C.L.7
-
97
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
DOI 10.1056/NEJMoa050092
-
Curtin JA, Fridlyand J, Kageshita T et al. Distinct sets of genetic alterations in melanoma. N. Engl. J Med. 353(20), 2135-2147 (2005). (Pubitemid 41653105)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.20
, pp. 2135-2147
-
-
Curtin, J.A.1
Fridlyand, J.2
Kageshita, T.3
Patel, H.N.4
Busam, K.J.5
Kutzner, H.6
Cho, K.-H.7
Aiba, S.8
Brocker, E.-B.9
Leboit, P.E.10
Pinkel, D.11
Bastian, B.C.12
-
98
-
-
0036645090
-
Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness
-
Wang E, Miller LD, Ohnmacht GA et al. Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness. Cancer Res. 62(13), 3581-3586 (2002). (Pubitemid 34728828)
-
(2002)
Cancer Research
, vol.62
, Issue.13
, pp. 3581-3586
-
-
Wang, E.1
Miller, L.D.2
Ohnmacht, G.A.3
Mocellin, S.4
Perez-Diez, A.5
Petersen, D.6
Zhao, Y.7
Simon, R.8
Powell, J.I.9
Asaki, E.10
Alexander, H.R.11
Duray, P.H.12
Herlyn, M.13
Restifo, N.P.14
Liu, E.T.15
Rosenberg, S.A.16
Marincola, F.M.17
-
99
-
-
33750600634
-
Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: The oblimersen melanoma study group
-
DOI 10.1200/JCO.2006.06.0483
-
Bedikian AY, Millward M, Pehamberger H et al. Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group. J. Clin. Oncol. 24(29), 4738-4745 (2006). (Pubitemid 46630937)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.29
, pp. 4738-4745
-
-
Bedikian, A.Y.1
Millward, M.2
Pehamberger, H.3
Conry, R.4
Gore, M.5
Trefzer, U.6
Pavlick, A.C.7
Deconti, R.8
Hersh, E.M.9
Hersey, P.10
Kirkwood, J.M.11
Haluska, F.G.12
-
100
-
-
66149176908
-
Erlotinib and bevacizumab have synergistic activity against melanoma
-
Schicher N, Paulitschke V, Swoboda A et al. Erlotinib and bevacizumab have synergistic activity against melanoma. Clin. Cancer Res. 15(10), 3495-3502 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, Issue.10
, pp. 3495-3502
-
-
Schicher, N.1
Paulitschke, V.2
Swoboda, A.3
-
101
-
-
70449456191
-
Autologous tumor derived gp96 evokes a tumor specific immune response in recurrent glioma patients that correlates with clinical response to therapy
-
Presented at
-
Parsa A, Crane C, Wilson S et al. Autologous tumor derived gp96 evokes a tumor specific immune response in recurrent glioma patients that correlates with clinical response to therapy. Presented at: AACR-NCI-EORTC International Conference. San Francisco, CA, USA, 22-26 October 2007.
-
AACR-NCI-EORTC International Conference. San Francisco, CA, USA, 22-26 October 2007
-
-
Parsa, A.1
Crane, C.2
Wilson, S.3
-
102
-
-
80052495863
-
Pilot trial of vaccination with autologous tumour-derived Gp-96 heat shock protein-peptide complex (HSPPC-96) in patients after surgery for gastric carcinoma
-
Heike M. Pilot trial of vaccination with autologous tumour-derived Gp-96 heat shock protein-peptide complex (HSPPC-96) in patients after surgery for gastric carcinoma. Proc. Am. Soc. Clin. Onc. (ASCO) (2000).
-
Proc. Am. Soc. Clin. Onc. (ASCO) (2000)
-
-
Heike, M.1
-
103
-
-
33645272083
-
Phase I trial of vaccination with autologous-tumor derived gp96 (oncophage) in patients after surgery for gastric cancer
-
Hertkorn C, Lehr A, Woelfel T et al. Phase I trial of vaccination with autologous-tumor derived gp96 (oncophage) in patients after surgery for gastric cancer. Proc. Am. Soc. Clin. Onc. (ASCO) (2002).
-
Proc. Am. Soc. Clin. Onc. (ASCO) (2002)
-
-
Hertkorn, C.1
Lehr, A.2
Woelfel, T.3
-
104
-
-
42149092508
-
Vaccination of metastatic renal cell carcinoma patients with autologous tumour-derived vitespen vaccine: Clinical findings
-
DOI 10.1038/sj.bjc.6604266, PII 6604266
-
Jonasch E, Wood C, Tamboli P et al. Vaccination of metastatic renal cell carcinoma patients with autologous tumour-derived vitespen vaccine: clinical findings. Br. J. Cancer 98(8), 1336-1341 (2008). (Pubitemid 351543568)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.8
, pp. 1336-1341
-
-
Jonasch, E.1
Wood, C.2
Tamboli, P.3
Pagliaro, L.C.4
Tu, S.M.5
Kim, J.6
Srivastava, P.7
Perez, C.8
Isakov, L.9
Tannir, N.10
-
105
-
-
33645480924
-
A multicenter randomized study of adjuvant heat shock protein peptide complex 96 (HSPPC-96) vaccine in patients with high risk of recurrence after nephrectomy for renal cell carcinoma (RCC) - A preliminary report
-
Abstract 2618
-
Wood CG, Escudier B, Gorelov S. A multicenter randomized study of adjuvant heat shock protein peptide complex 96 (HSPPC-96) vaccine in patients with high risk of recurrence after nephrectomy for renal cell carcinoma (RCC) - a preliminary report. J. Clin. Oncol. 22(14 Suppl.) (2004) (Abstract 2618).
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.14 SUPPL.
-
-
Wood, C.G.1
Escudier, B.2
Gorelov, S.3
-
106
-
-
74949109884
-
Survival update from multicenter, randomized, Phase III trial of vitespen versus observation as adjuvant therapy for renal cell carcinoma in patients at high risk of recurrence
-
Abstract 3009
-
Wood CG, Srivastava P, Lacombe L et al. Survival update from multicenter, randomized, Phase III trial of vitespen versus observation as adjuvant therapy for renal cell carcinoma in patients at high risk of recurrence. J. Clin. Oncol. 27(15 Suppl.) (2009) (Abstract 3009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.15 SUPPL.
-
-
Wood, C.G.1
Srivastava, P.2
Lacombe, L.3
-
107
-
-
34347380750
-
A Phase I pilot study of autologous heat shock protein vaccine HSPPC-96 in patients with resected pancreatic adenocarcinoma
-
Maki E, Livingston PO, Lewis JJ et al. A Phase I pilot study of autologous heat shock protein vaccine HSPPC-96 in patients with resected pancreatic adenocarcinoma. Dig. Dis. Sci. 52(8), 1964-1972 (2007).
-
(2007)
Dig. Dis. Sci.
, vol.52
, Issue.8
, pp. 1964-1972
-
-
Maki, E.1
Livingston, P.O.2
Lewis, J.J.3
-
108
-
-
84895345866
-
Effective vaccines of autologous cancer-derived heat shock protein gp70-complexes in patients with cancer malignancies (pancreatic carcinoma, colo-rectal cancer)
-
Dong J, Wei J. Effective vaccines of autologous cancer-derived heat shock protein gp70-complexes in patients with cancer malignancies (pancreatic carcinoma, colo-rectal cancer). Proc. Am. Soc. Clin. Onc. (ASCO) (2005).
-
Proc. Am. Soc. Clin. Onc. (ASCO) (2005)
-
-
Dong, J.1
Wei, J.2
-
109
-
-
70449437422
-
An autologous tumor-derived heat shock protein vaccine for high European Medicines Agency risk ovarian cancer
-
Li Z, Nash JD, Qiao Y. An autologous tumor-derived heat shock protein vaccine for high European Medicines Agency risk ovarian cancer. Proc. Am. Soc. Clin. Onc. (ASCO) (2005).
-
Proc. Am. Soc. Clin. Onc. (ASCO) (2005)
-
-
Li, Z.1
Nash, J.D.2
Qiao, Y.3
-
110
-
-
4043166052
-
Safety and efficacy of heat shock protein-peptide 96 complex (HSPPC-96) in low grade lymphoma
-
Abstract 2294
-
Younes A, Fayad LE, Pro B. Safety and efficacy of heat shock protein-peptide 96 complex (HSPPC-96) in low grade lymphoma. Proc. Am. Soc. Clin. Onc. (ASCO) 22 (2003) (Abstract 2294).
-
(2003)
Proc. Am. Soc. Clin. Onc. (ASCO)
, pp. 22
-
-
Younes, A.1
Fayad, L.E.2
Pro, B.3
-
111
-
-
1642463793
-
A phase II study of heat shock protein-peptide complex-96 vaccine therapy in patients with indolent non-Hodgkin's lymphoma
-
Younes A. A Phase II study of heat shock protein-peptide complex-96 vaccine therapy in patients with indolent non- Hodgkin's lymphoma. Clin. Lymphoma 4(3), 183-185 (2003). (Pubitemid 38128684)
-
(2003)
Clinical Lymphoma
, vol.4
, Issue.3
, pp. 183-185
-
-
Younes, A.1
-
112
-
-
33846332800
-
Experience with heat shock protein-peptide complex 96 vaccine therapy in patients with indolent non-hodgkin lymphoma
-
DOI 10.1002/cncr.22389
-
Oki Y, McLaughlin P, Fayad LE et al. Experience with heat shock protein- peptide complex 96 vaccine therapy in patients with indolent non-Hodgkin lymphoma. Cancer 109(1), 77-83 (2007). (Pubitemid 46120196)
-
(2007)
Cancer
, vol.109
, Issue.1
, pp. 77-83
-
-
Oki, Y.1
McLaughlin, P.2
Fayad, L.E.3
Pro, B.4
Mansfield, P.F.5
Clayman, G.L.6
Medeiros, L.J.7
Kwak, L.W.8
Srivastava, P.K.9
Younes, A.10
-
113
-
-
70449399950
-
-
US FDA www.fda.gov
-
-
-
-
114
-
-
70449410315
-
-
Antigenics www.antigenics.com
-
Antigenics
-
-
-
115
-
-
70449443098
-
-
European Medicines Agency www.emea.europa.eu
-
-
-
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