Effects of ectopic expression of human telomerase reverse transcriptase on immortalization of feather keratinocyte stem cells

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution

Volumn 312, Issue 8, 2009, Pages 872-884

  Xu, Yulin ^a   Yu, Minli ^a   Wu, Fabai ^a   Sun, Jianguo ^a   Wood, Chris ^a   Hattori, Masa Aki ^b   Wang, Jinfu ^a   Xi, Yongmei ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; TELOMERASE; TERT PROTEIN, HUMAN;

ANIMAL; ARTICLE; CELL LINE; CHICKEN; CYTOLOGY; ENZYMOLOGY; FEATHER; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HUMAN; IN SITU HYBRIDIZATION; KERATINOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TRANSFORMED; CHICKENS; FEATHERS; FLUORESCENT ANTIBODY TECHNIQUE; GREEN FLUORESCENT PROTEINS; HUMANS; IN SITU HYBRIDIZATION; KERATINOCYTES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS; TELOMERASE;

MUS;

EID: 70449107242     PISSN: 15525007     EISSN: 15525015     Source Type: Journal    
DOI: 10.1002/jez.b.21302     Document Type: Article

References (43)

1. Blackburn EH. 2001. Switching and signaling at the telomere. Cell 106:661-673.
2. Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu C-k, Morin GB, Harley CB, Shay JW, Lichtsteiner S, Wright WE. 1998. Extension of life-span by introduction of telomerase into normal human cells. Science 279:349-352.
3. Bosoy D, Peng Y, Mian IS, Lue NF. 2003. Conserved N-terminal Motifs of Telomerase Reverse Transcriptase required for ribonucleoprotein assembly in vivo. J Biol Chem 278:3882-3890.
4. Chen JL, Blasco MA, Greider CW. 2000. Secondary structure of vertebrate telomerase RNA. Cell 100:503-514.
5. Cong YS, Wen J, Bacchetti S. 1999.The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter. Hum Mol Genet 8:137-142.
6. Cong YS, Wright WE, Shay JW. 2002. Human telomerase and its regulation. Microbiol Mol Biol 66:407-425.
7. Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, Harley CB, Bacchetti S. 1992. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 11:1921-1929.
8. Cui W, Wylie D, Aslam S, Dinnyes A, King T, Wilmut I, Clark AJ. 2003. Telomerase-immortalized sheep fibroblasts can be reprogrammed by nuclear transfer to undergo early development. Biol Reprod 69:15-21.
9. Delany ME, Daniels LM. 2003. The chicken telomerase RNA gene: conservation of sequence, regulatory elements and synteny among viral, avian and mammalian genomes. Cytogenet Genome Res 102:309-317.
10. Delany ME, Daniels LM. 2004. The chicken telomerase reverse transcriptase (chTERT): molecular and cytogenetic characterization with a comparative analysis. Gene 339:61-69.
11. Delany ME, Krupkin AB, Miller MM. 2000. Organization of telomere sequences in birds: Evidence for arrays of extreme length and for in vivo shortening. Cytogenet Cell Genet 90:139-145.
12. Dennis JE, Caplan AI. 1996. Differentiation potential of conditionally immortalized mesenchymal progenitor cells from adult marrow of an H-2KbtsA58 transgenic mouse. J Cell Physiol 167:523-538.
13. Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O. 1995. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92:9363-9367.
14. Eyal GH, Kochav S. 1976. From cleavage to primitive streak formation: a complementary normal table and a new look at the first stages of development of the chick I. General morphology. Dev Biol 49:321-337.
15. Forsyth NR, Wright WE, Shay JW. 2002. Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again. Differentiation 69: 188-197.
16. Fuchs E, Tumbar T, Guasch G. 2004. Socializing with the neighbors: stem cells and their niche. Cell 116:769-778.
17. Georgios ML, Saretzki G, Hall J. 2005. Endogenous and ectopic expression of telomere regulating genes in chicken embryonic fibroblasts. Biochem Biophys Res Commun 335:240-246.
18. Hayflick L. 1976. The cell biology of human aging. N Engl J Med 295:1302-1308.
19. Huang GP, Pan ZJ, Huang JP, Yang JF, Guo CJ, Wang YG, Zheng Q, Chen R, Xu YL, Wang GZ, Xi YM, Shen D, Jin J, Wang JF. 2008. Proteomic analysis of human bone marrow mesenchymal stem cells transduced with human telomerase reverse transcriptase gene during proliferation. Cell Prolif 41:625-644.
20. Keppler BR, Jarstfer MB. 2004. Inhibition of telomerase activity by preventing proper assemblage. Biochemistry 43:334-343.
21. Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway DA, Klingelhutz AJ. 1998. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 396:84-88.
22. Lee BY, Han JA, Im JS, Morrone A, Johung K, Goodwin EC, Kleijer WJ, DiMaio D, Hwang ES. 2006. Senescence-associated beta-galactosidase is lysosomal beta-galactosidase. Aging Cell 5:187-195.
23. Lima L, Macieira-Coelho A. 1972. Parameters of aging in chicken embryo fibroblasts cultivated in vitro. Exp Cell Res 70:279-284.
24. Nakamura TM, Morin GB, Chapman KB, Weinrich SL, Andrews WH, Lingner J, Harley CB, Cech TR. 1997. Telomerase catalytic subunit homologs from fission yeast and human. Science 277:955-959.
25. Roger H, Sawyer LWK. 2003. Avian skin development and the evolutionary origin of feathers. J Exp Zool 298B: 57-72.
26. Sarin KY, Cheung P, Gilison D, Lee E, Tennen RI, Wang E, Artandi MK, Oro AE, Artandi SE. 2005. Conditional telomerase induction causes proliferation of hair follicle stem cells. Nature 436:1048-1052.
27. Simonsen JL, Rosada C, Serakinci N, Justesen J, Stenderup K, Rattan SI, Jensen TG, Kassem M. 2002. Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nat Biotechnol 20:592-596.
28. Swanberg SE, Delany ME. 2003. Dynamics of telomere erosion in transformed and non-transformed avian cells in vitro. Cytogenet Genome Res 102:318-325.
29. Swanberg SE, Payne WS, Hunt HD, Dodgson JB, Delany ME. 2004. Telomerase activity and differential expression of telomerase genes and c-myc in chicken cells in vitro. Dev Dyn 231:14-21.
30. Taylor HA, Delany ME. 2000. Ontogeny of telomerase in chicken: impact of down regulation on preand postnatal telomere length in vivo. Development 42:613-621.
31. Vaziri H, Dragowska W, Allsopp RC, Thomas TE, Harley CB, Lansdorp PM. 1994. Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. Proc Nati Acad Sci USA 91:9857-9860.
32. Veitonmaki N, Fuxe J, Hultdin M, Roos G, Pettersson RF, Cao Y. 2003. Immortalization of bovine capillary endothelial cells by hTERT alone involves inactivation of endogenous p16-INK4A/pRB. FASEB J 17:764-766.
33. Venkatesan RN, Price C. 1998. Telomerase expression in chickens: constitutive activity in somatic tissues and downregulation in culture. Proc Natl Acad Sci USA 95: 14763-14768.
34. Widelitz RB, Jiang TX, Noveen A, Ting-Berreth SA, Yin E, Jung HS, Chuong CM. 1997. Molecular histology in skin appendage morphogenesis. Microsc Res Tech 38:452-465.
35. Wong SCLL, Ong CP, Wong SC, Ong LL, Er CP, Gao S, Yu H, So JB. 2003. Cloning of rat telomerase catalytic subunit functional domains, reconstitution of telomerase activity and enzymatic profile of pig and chicken tissues. Life Sci 73:2749-2760.
36. Xi YM, Nada Y, Soh T, Fujihara N, Hattori MA. 2003. Establishment of feather follicle stem cells as potential vehicles for delivering exogenous genes in birds. J Reprod Dev 49:213-219.
37. Xiang H, Wang J, Mao YW, Li DWC. 2000. hTERT Can Function with Rabbit Telomerase RNA: regulation of gene expression and attenuation of apoptosis. Biochem Biophys Res Commun 278:503-510.
38. Xu YL, Sun JG, Wu FB, Wood C, Hattori MA, Wang JF, Xi YM. 2009. Investigation of the plasticity of feather keratinocyte stem cells and the regeneration potential. BMC Cell Biol, in review.
39. Yang J, Chang E, Cherry AM, Bangs CD, Oei Y, Bodnar A, Bronstein A, Chiu CP, Herron GS. 1999. Human endothelial cell life extension by telomerase expression. J Biol Chem 274:26141-26148.
40. Yu M, Wu P, Widelitz RB, Chuong CM. 2002. The morphogenesis of feathers. Nature 420:308-312.
41. Yue Z, Jiang T-X, Widelitz RB, Chuong C-M. 2005. Mapping stem cell activities in the feather follicle. Nature 438:1026-1029.
42. Zhu LH, Zhou TJ, Shi GY, Zhang GL, Li SY. 2007. Expression of bcl-2 gene in EBV-transformed human gastric epithelial cell line GES-1. Nan Fang Yi Ke Da Xue Xue Bao 27:195-197.
43. Zou Y, Yi X, Wright WE, Shay JW. 2002. Human telomerase can immortalize indian muntjac cells. Exp Cell Res 281:63-76.