Can yeast be used to study mitochondrial diseases? Biolistic tRNA mutants for the analysis of mechanisms and suppressors

Mitochondrion

Volumn 9, Issue 6, 2009, Pages 408-417

  De Luca, Cristina ^a   Zhou, YouFang ^b   Montanari, Arianna ^a   Morea, Veronica ^a   Oliva, Romina ^c   Besagni, Celine ^b   Bolotin Fukuhara, Monique ^b   Frontali, Laura ^a   Francisci, Silvia ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

^c UNIVERSITY OF NAPLES PARTHENOPE   (Italy)

Author keywords

Mitochondrial disease; Suppressors of mitochondrial defects; Yeast model

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; LEUCINE TRANSFER RNA; LEUCINE TRANSFER RNA LIGASE; LYSINE TRANSFER RNA; MITOCHONDRIAL PROTEIN; PROTEIN TUF1; TRANSFER RNA; UNCLASSIFIED DRUG; VALINE TRANSFER RNA;

ARTICLE; BIOLISTIC TRANSFORMATION; BIOLOGICAL MODEL; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRAIT; GROWTH CURVE; MOLECULAR DYNAMICS; NONHUMAN; NORTHERN BLOTTING; NUCLEIC ACID BASE SUBSTITUTION; OXYGEN CONSUMPTION; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; SUPPRESSOR GENE; YEAST;

BASE SEQUENCE; BIOLISTICS; BLOTTING, NORTHERN; HUMANS; MICROBIAL VIABILITY; MITOCHONDRIAL DISEASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHENOTYPE; POINT MUTATION; RNA, TRANSFER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUPPRESSION, GENETIC;

EID: 70449093738     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2009.07.004     Document Type: Article

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