Potency of HIV-1 envelope glycoprotein gp120 antibodies to inhibit the interaction of DC-SIGN with HIV-1 gp120

Virology

Volumn 329, Issue 2, 2004, Pages 465-476

  Lekkerkerker, Annemarie N ^a   Ludwig, Irene S ^a   Van Vliet, Sandra J ^a   Van Kooyk, Yvette ^a   Geijtenbeek, Teunis B H ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Antibodies; CD4; DC SIGN; Dendritic cells; gp120; HIV 1

Indexed keywords

GLYCOPROTEIN GP 120; INTERCELLULAR ADHESION MOLECULE 3; POLYCLONAL ANTIBODY; PROTEIN ANTIBODY; VIRUS ENVELOPE PROTEIN;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DENDRITIC CELL; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN PROTEIN INTERACTION;

ANIMALS; ANTIGEN-ANTIBODY REACTIONS; ANTIGENS, CD4; CELL ADHESION MOLECULES; CELLS, CULTURED; GLYCOSYLATION; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; LECTINS, C-TYPE; MICE; RECEPTORS, CELL SURFACE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 7044263030     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2004.08.028     Document Type: Article

References (53)

1. D.A. Calarese, C.N. Scanlan, M.B. Zwick, S. Deechongkit, Y. Mimura, R. Kunert, P. Zhu, M.R. Wormald, R.L. Stanfield, K.H. Roux, J.W. Kelly, P.M. Rudd, R.A. Dwek, H. Katinger, D.R. Burton, and I.A. Wilson Antibody domain exchange is an immunological solution to carbohydrate cluster recognition Science 300 2003 2065
2. P.U. Cameron, P.S. Freudenthal, J.M. Barker, S. Gezelter, K. Inaba, and R.M. Steinman Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells Science 257 1992 383 387
3. L.A. Cavacini, C.L. Emes, J. Power, A. Buchbinder, S. Zolla-Pazner, and M.R. Posner Human monoclonal antibodies to the V3 loop of HIV-1 gp120 mediate variable and distinct effects on binding and viral neutralization by a human monoclonal antibody to the CD4 binding site J. Acquired Immune Defic. Syndr. 6 1993 353 358
4. L. Cavacini, M. Duval, L. Song, R. Sangster, S.H. Xiang, J. Sodroski, and M. Posner Conformational changes in env oligomer induced by an antibody dependent on the V3 loop base AIDS 17 2003 685 689
5. A.J. Conley, M.K. Gorny, J.A. Kessler, L.J. Boots, M. Ossorio-Castro, S. Koenig, D.W. Lineberger, E.A. Emini, C. Williams, and S. Zolla-Pazner Neutralization of primary human immunodeficiency virus type 1 isolates by the broadly reactive anti-V3 monoclonal antibody, 447-52D J. Virol. 68 1994 6994 7000
6. H. Feinberg, D.A. Mitchell, K. Drickamer, and W.I. Weis Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR Science 294 2001 2163 2166
7. T.B. Geijtenbeek, D.J. Krooshoop, D.A. Bleijs, S.J. Van Vliet, G.C. van Duijnhoven, V. Grabovsky, R. Alon, C.G. Figdor, and Y. Van Kooyk DC-SIGNâ€"ICAM-2 interaction mediates dendritic cell trafficking Nat. Immunol. 1 2000 353 357
8. T.B. Geijtenbeek, D.S. Kwon, R. Torensma, S.J. Van Vliet, G.C. van Duijnhoven, J. Middel, I.L. Cornelissen, H.S. Nottet, V.N. KewalRamani, D.R. Littman, C.G. Figdor, and Y. Van Kooyk DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells Cell 100 2000 587 597
9. T.B. Geijtenbeek, R. Torensma, S.J. Van Vliet, G.C. van Duijnhoven, G.J. Adema, Y. Van Kooyk, and C.G. Figdor Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses Cell 100 2000 575 585
10. T.B. Geijtenbeek, G.C. van Duijnhoven, S.J. Van Vliet, E. Krieger, G. Vriend, C.G. Figdor, and Y. Van Kooyk Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1 J. Biol. Chem. 277 2002 11314 11320
11. T.B. Geijtenbeek, S.J. Van Vliet, E.A. Koppel, M. Sanchez-Hernandez, C.M. Vandenbroucke-Grauls, B. Appelmelk, and Y. Van Kooyk Mycobacteria target DC-SIGN to suppress dendritic cell function J. Exp. Med. 197 2003 7 17
12. M.K. Gorny, J.Y. Xu, V. Gianakakos, S. Karwowska, C. Williams, H.W. Sheppard, C.V. Hanson, and S. Zolla-Pazner Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope glycoprotein Proc. Natl. Acad. Sci. U.S.A. 88 1991 3238 3242
13. M.K. Gorny, J.Y. Xu, S. Karwowska, A. Buchbinder, and S. Zolla-Pazner Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120 J. Immunol. 150 1993 635 643
14. M.K. Gorny, J.P. Moore, A.J. Conley, S. Karwowska, J. Sodroski, C. Williams, S. Burda, L.J. Boots, and S. Zolla-Pazner Human anti-V2 monoclonal antibody that neutralizes primary but not laboratory isolates of human immunodeficiency virus type 1 J. Virol. 68 1994 8312 8320
15. M.K. Gorny, T.C. VanCott, C. Hioe, Z.R. Israel, N.L. Michael, A.J. Conley, C. Williams, J.A. Kessler, P. Chigurupati, S. Burda, and S. Zolla-Pazner Human monoclonal antibodies to the V3 loop of HIV-1 with intra- and interclade cross-reactivity J. Immunol. 159 1997 5114 5122
16. N.L. Haigwood, C.B. Barker, K.W. Higgins, P.V. Skiles, G.K. Moore, K.A. Mann, D.R. Lee, J.W. Eichberg, and K.S. Steimer Evidence for neutralizing antibodies directed against conformational epitopes of HIV-1 gp120 Vaccines 90 1990 Cold Spring Harbor Laboratories New York 313 320
17. N.L. Haigwood, J.R. Shuster, G.K. Moore, H. Lee, P.V. Skiles, K.W. Higgins, P.J. Barr, C. George-Nascimento, and K.S. Steimer Importance of hypervariable regions of HIV-1 gp120 in the generation of virus neutralizing antibodies AIDS Res. Hum. Retroviruses 6 1990 855 869
18. P.W. Hong, K.B. Flummerfelt, A. de Parseval, K. Gurney, J.H. Elder, and B. Lee Human immunodeficiency virus envelope (gp120) binding to DC-SIGN and primary dendritic cells is carbohydrate dependent but does not involve 2G12 or cyanovirin binding sites: implications for structural analyses of gp120-DC-SIGN binding J. Virol. 76 2002 12855 12865
19. M. Koch, M. Pancera, P.D. Kwong, P. Kolchinsky, C. Grundner, L. Wang, W.A. Hendrickson, J. Sodroski, and R. Wyatt Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition Virology 313 2003 387 400
20. D.S. Kwon, G. Gregorio, N. Bitton, W.A. Hendrickson, and D.R. Littman DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection Immunity 16 2002 135 144
21. P.D. Kwong, R. Wyatt, J. Robinson, R.W. Sweet, J. Sodroski, and W.A. Hendrickson Structure of an HIV gp 120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody Nature 393 1998 648 659
22. P.D. Kwong, M.L. Doyle, D.J. Casper, C. Cicala, S.A. Leavitt, S. Majeed, T.D. Steenbeke, M. Venturi, I. Chaiken, M. Fung, H. Katinger, P.W. Parren, J. Robinson, D. Van Ryk, L. Wang, D.R. Burton, E. Freire, R. Wyatt, J. Sodroski, W.A. Hendrickson, and J. Arthos HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature 420 2002 678 682
23. B. Lee, G. Leslie, E. Soilleux, U. O'Doherty, S. Baik, E. Levroney, K. Flummerfelt, W. Swiggard, N. Coleman, M. Malim, and R.W. Doms Cis expression of DC-SIGN allows for more efficient entry of human and simian immunodeficiency viruses via CD4 and a coreceptor J. Virol. 75 2001 12028 12038
24. C.K. Leonard, M.W. Spellman, L. Riddle, R.J. Harris, J.N. Thomas, and T.J. Gregory Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells J. Biol. Chem. 265 1990 10373 10382
25. J.A. Levy, A.D. Hoffman, S.M. Kramer, J.A. Landis, J.M. Shimabukuro, and L.S. Oshiro Isolation of lymphocytopathic retroviruses from San Francisco patients with AIDS Science 225 1984 840 842
26. C.L. Lin, A.K. Sewell, G.F. Gao, K.T. Whelan, R.E. Phillips, and J.M. Austyn Macrophage-tropic HIV induces and exploits dendritic cell chemotaxis J. Exp. Med. 192 2000 587 594
27. J. Lue, M. Hsu, D. Yang, P. Marx, Z. Chen, and C. Cheng-Mayer Addition of a single gp120 Glycan confers increased binding to dendritic cell-specific ICAM-3-grabbing nonintegrin and neutralization escape to human immunodeficiency virus type 1 J. Virol. 76 2002 10299 10306
28. D. McDonald, L. Wu, S.M. Bohks, V.N. KewalRamani, D. Unutmaz, and T.J. Hope Recruitment of HIV and its receptors to dendritic cell-T cell junctions Science 300 2003 1295 1297
29. J.P. Moore, and J. Sodroski Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein J. Virol. 70 1996 1863 1872
30. J.P. Moore, H. Yoshiyama, D.D. Ho, J.E. Robinson, and J. Sodroski Antigenic variation in gp120s from molecular clones of HIV-1 LAI AIDS Res. Hum. Retroviruses 9 1993 1185 1193
31. C. Nobile, A. Moris, F. Porrot, N. Sol-Foulon, and O. Schwartz Inhibition of human immunodeficiency virus type 1 env-mediated fusion by DC-SIGN J. Virol. 77 2003 5313 5323
32. S. Pohlmann, F. Baribaud, and R.W. Doms DC-SIGN and DC-SIGNR: helping hands for HIV Trends Immunol. 22 2001 643 646
33. S. Pohlmann, G.J. Leslie, T.G. Edwards, T. Macfarlan, J.D. Reeves, K. Hiebenthal-Millow, F. Kirchhoff, F. Baribaud, and R.W. Doms DC-SIGN interactions with human immunodeficiency virus: virus binding and transfer are dissociable functions J. Virol. 75 2001 10523 10526
34. M. Pope, M.G. Betjes, N. Romani, H. Hirmand, P.U. Cameron, L. Hoffman, S. Gezelter, G. Schuler, and R.M. Steinman Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1 Cell 78 1994 389 398
35. M.R. Posner, L.A. Cavacini, C.L. Emes, J. Power, and R. Byrn Neutralization of HIV-1 by F105, a human monoclonal antibody to the CD4 binding site of gp120 J. Acquired Immune Defic. Syndr. 6 1993 7 14
36. C.D. Rizzuto, R. Wyatt, N. Hernandez-Ramos, Y. Sun, P.D. Kwong, W.A. Hendrickson, and J. Sodroski A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding Science 280 1998 1949 1953
37. P. Roben, J.P. Moore, M. Thali, J. Sodroski, C.F. Barbas III, and D.R. Burton Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1 J. Virol. 68 1994 4821 4828
38. R. Sanchez-Pescador, M.D. Power, P.J. Barr, K.S. Steimer, M.M. Stempien, S.L. Brown-Shimer, W.W. Gee, A. Renard, A. Randolph, and J.A. Levy Nucleotide sequence and expression of an AIDS-associated retrovirus (ARV-2) Science 227 1985 484 492
39. Q.J. Sattentau, J.P. Moore, F. Vignaux, F. Traincard, and P. Poignard Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding J. Virol. 67 1993 7383 7393
40. C.J. Scandella, J. Kilpatrick, W. Lidster, C. Parker, J.P. Moore, G.K. Moore, K.A. Mann, P. Brown, S. Coates, and B. Chapman Nonaffinity purification of recombinant gp120 for use in AIDS vaccine development AIDS Res. Hum. Retroviruses 9 1993 1233 1244
41. C.N. Scanlan, R. Pantophlet, M.R. Wormald, S.E. Ollmann, R. Stanfield, I.A. Wilson, H. Katinger, R.A. Dwek, P.M. Rudd, and D.R. Burton The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1->2 mannose residues on the outer face of gp120 J. Virol. 76 2002 7306 7321
42. R.F. Speck, K. Wehrly, E.J. Platt, R.E. Atchison, I.F. Charo, D. Kabat, B. Chesebro, and M.A. Goldsmith Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop J. Virol. 71 1997 7136 7139
43. K.S. Steimer, J.P. Puma, M.D. Power, M.A. Powers, C. George-Nascimento, J.C. Stephans, J.A. Levy, R. Sanchez-Pescador, P.A. Luciw, and P.J. Barr Differential antibody responses of individuals infected with AIDS-associated retroviruses surveyed using the viral core antigen p25gag expressed in bacteria Virology 150 1986 283 290
44. M. Thali, J.P. Moore, C. Furman, M. Charles, D.D. Ho, J. Robinson, and J. Sodroski Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120â€"CD4 binding J. Virol. 67 1993 3978 3988
45. A. Trkola, M. Purtscher, T. Muster, C. Ballaun, A. Buchacher, N. Sullivan, K. Srinivasan, J. Sodroski, J.P. Moore, and H. Katinger Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1 J. Virol. 70 1996 1100 1108
46. Y. Van Kooyk, and T.B. Geijtenbeek DC-SIGN: escape mechanism for pathogens Nat. Rev., Immunol. 3 2003 697 709
47. X. Wei, J.M. Decker, S. Wang, H. Hui, J.C. Kappes, X. Wu, J.F. Salazar-Gonzalez, M.G. Salazar, J.M. Kilby, M.S. Saag, N.L. Komarova, M.A. Nowak, B.H. Hahn, P.D. Kwong, and G.M. Shaw Antibody neutralization and escape by HIV-1 Nature 422 2003 307 312
48. L. Wu, N.P. Gerard, R. Wyatt, H. Choe, C. Parolin, N. Ruffing, A. Borsetti, A.A. Cardoso, E. Desjardin, W. Newman, C. Gerard, and J. Sodroski CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5 Nature 384 1996 179 183
49. R. Wyatt, and J. Sodroski The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens Science 280 1998 1884 1888
50. R. Wyatt, P.D. Kwong, E. Desjardins, R.W. Sweet, J. Robinson, W.A. Hendrickson, and J.G. Sodroski The antigenic structure of the HIV gp120 envelope glycoprotein Nature 393 1998 705 711
51. S.H. Xiang, N. Doka, R.K. Choudhary, J. Sodroski, and J.E. Robinson Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodies AIDS Res. Hum. Retroviruses 18 2002 1207 1217
52. X. Zhu, C. Borchers, R.J. Bienstock, and K.B. Tomer Mass spectrometric characterization of the glycosylation pattern of HIVâ€"gp120 expressed in CHO cells Biochemistry 39 2000 11194 11204
53. S. Zolla-Pazner, J. O'Leary, S. Burda, M.K. Gorny, M. Kim, J. Mascola, and F. McCutchan Serotyping of primary human immunodeficiency virus type 1 isolates from diverse geographic locations by flow cytometry J. Virol. 69 1995 3807 3815