cis expression of DC-SIGN allows for more efficient entry of human and simian immunodeficiency viruses via CD4 and a coreceptor

Journal of Virology

Volumn 75, Issue 24, 2001, Pages 12028-12038

  Lee, B ^a   Leslie, G ^a   Soilleux, E ^a   O'Doherty, U ^a   Baik, S ^a   Levroney, E ^a   Flummerfelt, K ^a   Swiggard, W ^a   Coleman, N ^a   Malim, M ^a   Doms, R W ^a  

^a 3825 Molecular Sciences Building ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD209 ANTIGEN; CD4 ANTIGEN; GLYCOPROTEIN GP 120; LECTIN; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOHISTOCHEMISTRY; LEUKEMIA CELL LINE; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SIMIAN IMMUNODEFICIENCY VIRUS; T LYMPHOCYTE; TARGET CELL; VIRUS INFECTION; VIRUS REPLICATION;

ANTIGENS, CD4; CELL ADHESION MOLECULES; CELL LINE; HIV; HUMANS; LECTINS; LECTINS, C-TYPE; RECEPTORS, CCR5; RECEPTORS, CELL SURFACE; RECEPTORS, CXCR4; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS REPLICATION;

EID: 0035194354     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.24.12028-12038.2001     Document Type: Article

References (41)

1. A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
2. The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses
3. Functional and antigenic chracterization of human, rhesus macaque, pigtailed macaque, and murine DC-SIGN
4. A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection
5. Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
6. A single amino acid substitution in the V1 loop of human immunodeficiency virus type 1 gp120 alters cellular tropism
7. Sequence and expression of a membrane-associated C-type lectin that exhibits CD4-independent binding of human immunodeficiency virus envelope glycoprotein gp120
8. + T-cell lines determined by the capacity to exploit low concentrations of CCR5
9. Beyond receptor expression: The influence of receptor conformation, density, and affinity in HIV-1 infection
10. The plasma membrane as a combat zone in the HIV battlefield
11. Chemokine and orphan receptors in HIV-2 and SIV tropism and pathogenesis
12. Use of GPR1, GPR15, and STRL33 as coreceptors by diverse human immunodeficiency virus type 1 and simian immunodeficiency virus envelope proteins
13. Host-derived ICAM-1 glycoproteins is incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity
14. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
15. Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses
16. CD14 expression and binding of lipopolysaccharide to alveolar macrophages and monocytes
17. HIV infection of placental macrophages: Their potential role in vertical transmission
18. HIV-1 in human alveolar macrophages from infected patients is latent in vivo but replicates after in vitro stimulation
19. Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
20. Surface CD4 is critical to in vitro HIV infection of human alveolar macrophages
21. Immunohistochemical localization of human immunodeficiency virus p24 antigen in placental tissue
22. Human immunodeficiency virus type I attachment to HeLa CD4 cells is CD4 independent and gp120 dependent and requires cell surface heparans
23. Mechanisms for adaptation of simian immunodeficiency virus to replication in alveolar macrophages
24. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
25. Cell-surface heparan sulfate proteoglycan mediates HIV-1 infection of T-cell lines
26. HIV-1 infection of lung alveolar fibroblasts and macrophages in humans
27. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophage-tropic isolates of human immunodeficiency virus type 1
28. DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus
29. DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans
30. Mediation of human immunodeficiency virus type 1 binding by interaction of cell surface heparan sulfate proteoglycans with the V3 region of envelope gp120-gp41
31. Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes
32. Human immunodeficiency virus infection: In situ polymerase chain reaction localization in human placentas after in utero and in vitro infection
33. Relationship between load of virus in alveolar macrophages from human immunodeficiency virus type 1-infected persons, production of cytokines, and clinical status
34. DC-SIGN; a related gene, DC-SIGNR; and CD23 form a cluster on 19p13
35. DC-SIGN expression analysis in the adult fetus and placenta: Implications for the vertical transmission of HIV
36. DC-SIGN: A guide to some mysteries of dendritic cells
37. Affinity and kinetic analysis of the molecular interaction of ICAM-1 and leukocyte function-associated antigen-1
38. HIV-1 attachment: Another look
39. The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse
40. Proliferation of mature and immature subpopulations of bronchoalveolar monocytes/macrophages and peripheral blood monocytes
41. Expression cloning of the STRL33/BONZO/TYMSTR ligand reveals elements of CC, CXC, and CX3C chemokines