Cooperation of betulinic acid and TRAIL to induce apoptosis in tumor cells

Oncogene

Volumn 23, Issue 46, 2004, Pages 7611-7620

  Fulda, Simone ^a   Jeremias, Irmela ^b   Debatin, Klaus Michael ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b Dr von Haunersches Kinderspital ^*  (Germany)

Author keywords

Apoptosis; Betulinic acid; Cancer; Resistance; TRAIL

Indexed keywords

BETULIC ACID; CASPASE; CASPASE 8; CYTOCHROME C; DEATH RECEPTOR; PROTEIN BID; RECEPTOR; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL SPECIFICITY; CELL SURVIVAL; CELL TYPE; CLONOGENESIS; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; FEEDBACK SYSTEM; FIBROBLAST; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TUMOR CELL;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; INTRACELLULAR MEMBRANES; KIDNEY NEOPLASMS; MEDULLOBLASTOMA; MELANOMA; MEMBRANE GLYCOPROTEINS; MEMBRANE POTENTIALS; MITOCHONDRIA; NEUROBLASTOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 7044240646     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207970     Document Type: Article

References (31)

1. Algeciras-Schimnich A, Pietras EM, Barnhart BC, Legembre P, Vijayan S, Holbeck SL and Peter ME. (2003). Proc. Natl. Acad. Sci, 100, 11445-11450.
2. Ashkenazi A. (2002). Nat. Rev. Cancer, 2, 420-430.
3. Belka C, Schmid B, Marini P, Durand E, Rudner J, Faltin H, Bamberg M, Schulze-Osthoff K and Budach W. (2001). Oncogene, 20, 2190-2196.
4. Chinnaiyan AM, Prasad U, Shankar S, Hamstra DA, Shanaiah M, Chenevert TL, Ross BD and Rehemtulla A. (2000). Proc. Natl. Acad. Sci., 97, 1754-1759.
5. Debatin KM, Poncet D and Kroemer G. (2002). Oncogene, 21, 8786-8803.
6. Fulda S and Debatin KM. (2004). Cancer Res., 64, 337-346.
7. Fulda S, Friesen C and Debatin KM. (1998a). Klin. Pad., 210, 148-152.
8. Fulda S, Friesen C, Los M, Scaffidi C, Mier W, Benedict M, Nunez G, Krammer PH, Peter ME and Debatin KM. (1997). Cancer Res., 57, 4956-4964.
9. Fulda S, Meyer E and Debatin KM. (2002). Oncogene, 21, 2283-2294.
10. Fulda S, Scaffidi C, Susin SA, Krammer PH, Kroemer G, Peter ME and Debatin KM. (1998b). J. Biol. Chem., 273, 33942-33948.
11. Gliniak B and Le T. (1999). Cancer Res., 59, 6153-6158.
12. Hengartner MO. (2000). Nature, 407, 770-776.
13. Jo M, Kim TH, Seol DW, Esplen JE, Dorko K, Billiar TR and Strom SC. (2000). Nat. Med., 6, 564-567.
14. Johnstone RW, Ruefli AA and Lowe SW. (2002). Cell, 108, 153-164.
15. Keane MM, Rubinstein Y, Cuello M, Ettenberg SA, Banerjee P, Nau MM and Lipkowitz S. (2000). Breast Cancer Res. Treat., 64, 211-219.
16. Kim B and Feldman EL. (2002). J. Biol. Chem., 277, 27393-27400.
17. LeBlanc HN and Ashkenazi A. (2003). Cell Death Differ., 10, 66-75.
18. Lowe SW and Lin AW. (2000). Carcinogenesis, 21, 485-495.
19. Meng RD and El-Deiry WS. (2001). Exp. Cell Res., 262, 154-169.
20. Nagane M, Pan G, Weddle JJ, Dixit VM, Cavenee WK and Huang HJ. (2000). Cancer Res., 60, 847-853.
21. Nitsch R, Bechmann I, Deisz RA, Haas D, Lehmann TN, Wendling U and Zipp F. (2000). Lancet, 356, 827-828.
22. Peto J. (2001). Nature, 411, 390-395.
23. Pisha E, Chai H, Lee IS, Chagwedera TE, Farnsworth NR, Cordell GA, Beecher CW, Fong HH, Kinghorn AD, Brown DM and Pezzuto JM. (1995). Nat. Med., 1, 1046-1051.
24. Rohn TA, Wagenknecht B, Roth W, Naumann U, Gulbins E, Krammer PH, Walczak H and Weller M. (2001). Oncogene, 20, 4128-4137.
25. Scaffidi C, Fulda S, Debatin KM, Krammer PK and Peter ME. (1998). EMBO J., 17, 1675-1687.
26. Selzer E, Pimentel E, Wacheck V, Schlegel W, Pehamberger H, Jansen B and Kodym R. (2000). J. Invest. Dermatol., 114, 935-940.
27. Stahnke K, Eckhoff S, Mohr A, Meyer LH and Debatin KM. (2003). Leukemia, 17, 2130-2139.
28. Takimoto R and El-Deiry WS. (2000). Oncogene, 19, 1735-1743.
29. van Loo G, Saelens X, van Gurp M, MacFarlane M, Martin SJ and Vandenabeele P. (2002). Cell Death Differ., 9, 1031-1042.
30. Zhang HG, Wang J, Yang X, Hsu HC and Mountz JD. (2004). Oncogene, 23, 2009-2015.
31. Zuco V, Supino R, Righetti SC, Cleris L, Marchesi E, Gambacorti-Passerini C and Formelli F. (2002). Cancer Lett., 175, 17-25.